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Retraction: Evidence of brucellosis infection in the Milwaukee County Poor Farm Cemetery. 更正：撤回：证据布鲁氏菌感染在密尔沃基县贫困农场公墓。
microPublication biology Pub Date : 2026-04-29 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002176
{"title":"Retraction: Evidence of brucellosis infection in the Milwaukee County Poor Farm Cemetery.","authors":"","doi":"10.17912/micropub.biology.002176","DOIUrl":"10.17912/micropub.biology.002176","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.17912/micropub.biology.001601.].</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous and Sequential Coexposures of Serratia marcescens in Caenorhabditis elegans. 秀丽隐杆线虫中粘质沙雷菌的同时和顺序共暴露。
microPublication biology Pub Date : 2026-04-21 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002064
Emily B Smith, Jennifer D Gresham, Andrew Huang, Levi T Morran
{"title":"Simultaneous and Sequential Coexposures of <i>Serratia marcescens</i> in <i>Caenorhabditis elegans</i>.","authors":"Emily B Smith, Jennifer D Gresham, Andrew Huang, Levi T Morran","doi":"10.17912/micropub.biology.002064","DOIUrl":"https://doi.org/10.17912/micropub.biology.002064","url":null,"abstract":"<p><p>Coinfections are common in nature and include hosts simultaneously or sequentially exposed to different genotypes. We investigated the potential for simultaneous and sequential exposures to impact host fitness by exposing <i>Caenorhabditis elegans</i> hosts to different bacterial strains of <i>Serratia marcescens</i> . We found that in simultaneous exposures a highly virulent strain induced high mortality regardless of coexposure. In sequential exposures, the same highly virulent strain induced high mortality if it was the first strain introduced in a coexposure. Overall, we find host outcomes after coinfections may depend on particular parasite genotype combinations and infection timing.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13147295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effectiveness of Manuka Honey in Treating Staphylococcus aureus in C. elegans. 麦卢卡蜂蜜治疗秀丽隐杆线虫金黄色葡萄球菌的疗效。
microPublication biology Pub Date : 2026-04-21 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002081
Riley Lesko, Olivia Long, Kelsey Murphy
{"title":"The Effectiveness of Manuka Honey in Treating <i>Staphylococcus aureus</i> in <i>C. elegans</i>.","authors":"Riley Lesko, Olivia Long, Kelsey Murphy","doi":"10.17912/micropub.biology.002081","DOIUrl":"https://doi.org/10.17912/micropub.biology.002081","url":null,"abstract":"<p><p>Antibiotic resistance is a severe problem stemming from the overuse of antibiotics. Manuka honey, a unique honey from New Zealand, may serve as an alternative to traditional antibiotics for treating bacterial infections. A transgenic line of <i>Caenorhabditis elegans</i> , <i>hlh-30</i> ::3xFLAG::eGFP, was utilized as a stress reporter strain to quantify changes in GFP expression associated with host response to <i>S. aureus</i> infection and honey treatment. Imaging, longevity, and developmental assays all demonstrated that manuka honey reduced the host stress response to <i>S. aureus</i> infection in <i>C. elegans</i> . These findings suggest that manuka honey may be effective against <i>S. aureus</i> infections.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13147293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of a phage RecET recombinase system improves detection of shorter DNA fragments by an Acinetobacter baylyi ADP-ISx antibiotic gene biosensor strain. 噬菌体RecET重组酶系统的表达提高了贝氏不动杆菌ADP-ISx抗生素基因生物传感器菌株对较短DNA片段的检测。
microPublication biology Pub Date : 2026-04-21 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002084
Nicholas Rhyan, Issac S Koshy, Ryan Dinh, Anthony J VanDieren, Dennis M Mishler, Jeffrey E Barrick
{"title":"Expression of a phage RecET recombinase system improves detection of shorter DNA fragments by an <i>Acinetobacter baylyi</i> ADP-ISx antibiotic gene biosensor strain.","authors":"Nicholas Rhyan, Issac S Koshy, Ryan Dinh, Anthony J VanDieren, Dennis M Mishler, Jeffrey E Barrick","doi":"10.17912/micropub.biology.002084","DOIUrl":"https://doi.org/10.17912/micropub.biology.002084","url":null,"abstract":"<p><p>Naturally competent bacteria have been engineered into sequence-specific biosensors for environmental DNA, but low recombination rates limit detection of small DNA fragments. Phage recombinases are often used to increase the efficiency of integrating DNA constructs with short homology arms into bacterial genomes. We show that expression of a RecET homolog from an <i>Acinetobacter baumannii</i> prophage improves <i>Acinetobacter baylyi</i> ADP1-ISx biosensor detection of 120- and 200-bp fragments of an antibiotic resistance gene by approximately 10- to 20-fold. This strategy can potentially enable more sensitive detection of target sequences in highly degraded DNA from environmental samples by cell-based bacterial biosensors.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13147294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum: Sequence Analysis of Two B1 Mycobacteriophages, ElvisPhasley and Mesmerelda. 勘误：两个B1分枝噬菌体的序列分析，ElvisPhasley和promeselda。
microPublication biology Pub Date : 2026-04-17 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002147
{"title":"Corrigendum: Sequence Analysis of Two B1 Mycobacteriophages, ElvisPhasley and Mesmerelda.","authors":"","doi":"10.17912/micropub.biology.002147","DOIUrl":"10.17912/micropub.biology.002147","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.17912/micropub.biology.001964.].</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13092108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyst stem cell lineage GAL4 transgenes are robustly expressed in hub cells of the Drosophila testis stem cell niche. 囊肿干细胞系GAL4基因在果蝇睾丸干细胞生态位中心细胞中得到了显著表达。
microPublication biology Pub Date : 2026-04-17 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002106
Jennifer Viveiros, Erika Matunis
{"title":"Cyst stem cell lineage GAL4 transgenes are robustly expressed in hub cells of the <i>Drosophila</i> testis stem cell niche.","authors":"Jennifer Viveiros, Erika Matunis","doi":"10.17912/micropub.biology.002106","DOIUrl":"https://doi.org/10.17912/micropub.biology.002106","url":null,"abstract":"<p><p>Manipulating gene expression in the different cell types of the <i>Drosophila melanogaster</i> testis stem cell niche is critical to understanding its biology. Here, we tested the specificity of commonly used somatic cyst stem cell (CySC) lineage GAL4 drivers by assessing their abilities to promote loss of hub cell quiescence. We found that conditional reduction of the cell cycle inhibitor Retinoblastoma (Rbf) using <i>c587-GAL4</i> , <i>tj-GAL4</i> , <i>eyaA3-GAL4</i> , or <i>zfh1-GAL4</i> is sufficient to drive quiescent hub cells into mitosis, with increased penetrance at higher temperature due to higher GAL4 activity. Concomitant inhibition of GAL4 expression in hub cells via <i>hh-GAL80</i> eliminates hub cell proliferation, supporting that hub cells autonomously require Rbf to maintain quiescence. Thus, the activity of GAL4 drivers commonly used to manipulate the CySC lineage also functionally affect hub cells.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13135205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genome Sequence of the Gordonia rubripertincta Phage Yucky (Cluster CT). 红带戈登菌噬菌体Yucky的基因组序列（簇CT）。
microPublication biology Pub Date : 2026-04-16 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.001981
Caitlin Carter, Paxton R Evitts, Cheyenne Helton, Madeline F Kaiser, Jehee F Lee, Mackenzie M Peters, Cade Riley, Mackenzie L Sanders, Chad Walker, Danielle K Watt, Pamela L Connerly, Elizabeth E Rueschhoff
{"title":"Genome Sequence of the <i>Gordonia rubripertincta</i> Phage Yucky (Cluster CT).","authors":"Caitlin Carter, Paxton R Evitts, Cheyenne Helton, Madeline F Kaiser, Jehee F Lee, Mackenzie M Peters, Cade Riley, Mackenzie L Sanders, Chad Walker, Danielle K Watt, Pamela L Connerly, Elizabeth E Rueschhoff","doi":"10.17912/micropub.biology.001981","DOIUrl":"https://doi.org/10.17912/micropub.biology.001981","url":null,"abstract":"<p><p>Novel bacteriophage Yucky infects <i>Gordonia rubripertincta</i> , a bacterium known for its bioremediation potential. Phage particles have a siphovirus morphology and form 1.2 mm ± 0.5 mm-wide plaques (n=10). The genome of Yucky is 47,803 bp in length and encodes 74 protein-coding genes. The phage was assigned to cluster CT based on gene content similarity of at least 35% to actinobacteriophages. Thirty-nine gene products have putative functions, including genes involved in lysis, such as two lysin A domain genes as well as a lysin B gene.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insights into Human Ciliopathies: Gene Silencing of ropn1l and tex9 in Schmidtea mediterranea Indicate Association with Ciliary Structure and Motility. 对人类纤毛病的认识：地中海Schmidtea地中海中ropn11和tex9的基因沉默表明与纤毛结构和运动性有关。
microPublication biology Pub Date : 2026-04-16 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002035
Rachel Pitt, Chayanika Gogoi, Angelina Calnan, Lata Patnaik, Kristen C Johnson
{"title":"Insights into Human Ciliopathies: Gene Silencing of <i>ropn1l</i> and <i>tex9</i> in <i>Schmidtea</i> <i>mediterranea</i> Indicate Association with Ciliary Structure and Motility.","authors":"Rachel Pitt, Chayanika Gogoi, Angelina Calnan, Lata Patnaik, Kristen C Johnson","doi":"10.17912/micropub.biology.002035","DOIUrl":"https://doi.org/10.17912/micropub.biology.002035","url":null,"abstract":"<p><p>Cilia are microtubule-based organelles essential for motility, sensory signaling and development. In humans, motile cilia facilitate fluid movement, and their dysfunction causes ciliopathies, including infertility. We used RNAi-mediated knockdown of two human spermatid flagellar genes in <i>Schmidtea mediterranea</i> to assess effects on ciliary function and locomotion. Knockdown of <i>Smed-ropn1l</i> and <i>Smed-tex9</i> significantly reduced planarian swim rate by 26.4% and 33.2% respectively and shortened cilia by 37.1% and 38.7% respectively. These findings highlight the critical roles of ROPN1L and TEX9 in cilia function and the use of planarians as a valuable model for studying ciliopathies. &nbsp.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13133735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal and epidermal-specific analysis of ZIP-1 function and expression in Caenorhabditis elegans. ZIP-1在秀丽隐杆线虫肠道和表皮特异性分析。
microPublication biology Pub Date : 2026-04-16 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002114
James A Tirtorahardjo, Vladimir Lažetić, Emily R Troemel
{"title":"Intestinal and epidermal-specific analysis of ZIP-1 function and expression in <i>Caenorhabditis elegans</i>.","authors":"James A Tirtorahardjo, Vladimir Lažetić, Emily R Troemel","doi":"10.17912/micropub.biology.002114","DOIUrl":"https://doi.org/10.17912/micropub.biology.002114","url":null,"abstract":"<p><p>In the nematode <i>Caenorhabditis elegans</i> , infection with intracellular intestinal pathogens, including microsporidia and the Orsay virus, activates a transcriptional immune response called the intracellular pathogen response (IPR). Upregulation of about 1/3 of IPR genes requires a bZIP transcription factor ZIP-1. Previous work has demonstrated that ZIP-1 promotes anti-viral immunity, but how ZIP-1 protein is regulated and where it controls immune defense remains unclear. Here we show that intestinal-specific rescue of ZIP-1 drives IPR gene expression and promotes resistance to viral infection. We also show that proteasome blockade increases ZIP-1::GFP protein levels independently of the <i>zip-1</i> promoter.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13133734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Joubert syndrome gene fam149b1 homolog, xbx-4 , is required for multiple sensory behaviors. Joubert综合征基因fam149b1同源物xbx-4是多种感觉行为所必需的。
microPublication biology Pub Date : 2026-04-15 eCollection Date: 2026-01-01 DOI: 10.17912/micropub.biology.002141
Kaitlin Ching, Paul W Sternberg, Maureen M Barr
{"title":"Joubert syndrome gene <i>fam149b1</i> homolog, <i>xbx-4</i> , is required for multiple sensory behaviors.","authors":"Kaitlin Ching, Paul W Sternberg, Maureen M Barr","doi":"10.17912/micropub.biology.002141","DOIUrl":"https://doi.org/10.17912/micropub.biology.002141","url":null,"abstract":"<p><p>Many cells require cilia to receive environmental signals. Mutations in the ciliary gene <i>fam149b1</i> result in the ciliopathy Joubert syndrome. The <i>C. elegans</i> homolog of <i>fam149b1</i> , <i>xbx-4</i> , is required for normal cilium structure. We found that loss of XBX-4 hinders multiple cilium-mediated behaviors. <i>xbx-4</i> mutants display mild defects in male mating and nose touch behaviors and dramatic changes in social feeding. Unexpectedly, <i>xbx-4</i> mutants increased reversal behavior in response to ethanol, a control stimulus used in olfactory assays. Variation in the magnitude of phenotypes for different neurons is consistent with known cell-specific impacts of XBX-4 loss on cilium structure.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2026 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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