Medicina clinica (English ed.)最新文献_第3页

Predictive value of the combined use of NT-proBNP and CA125 biomarkers in a cohort of 138 patients with heart failure with reduced ejection fraction NT-proBNP和CA125生物标志物联合应用对138例射血分数降低的心力衰竭患者的预测价值

Medicina clinica (English ed.) Pub Date : 2026-03-01 Epub Date: 2026-03-19 DOI: 10.1016/j.medcle.2026.107277

Nouha Yacub Briceño , Alberto Jesús Torres Zamudio , Jorge Perea Armijo , José López-Aguilera

引用次数: 0

Ross syndrome: A case report 罗斯综合症：一份病例报告

Medicina clinica (English ed.) Pub Date : 2026-03-01 Epub Date: 2026-03-19 DOI: 10.1016/j.medcle.2026.107345

Emma Romeo-Iglesias , Martina Espasandín-Arias , Sandra Martínez-Fernández

引用次数: 0

Chronic diarrhea and infiltrative duodenal lesions caused by Chromobacterium violaceum in a kidney transplant recipient 肾移植受者紫色色杆菌致慢性腹泻及浸润性十二指肠病变1例

Medicina clinica (English ed.) Pub Date : 2026-03-01 Epub Date: 2026-04-01 DOI: 10.1016/j.medcle.2026.107294

Julya de Assis Sousa Morais , Diogo Buarque Cordeiro Cabral , Euclides Dias Martins Filho

引用次数: 0

Hypokalemic periodic paralysis type 1 with respiratory involvement: A case report and critical review of the diagnostic and therapeutic approach 伴呼吸系统受累的1型低钾血症性周期性麻痹：一例报告及诊断和治疗方法的重要回顾

Medicina clinica (English ed.) Pub Date : 2026-03-01 Epub Date: 2026-04-01 DOI: 10.1016/j.medcle.2026.107339

Rocío Fernández Gavira, Roberto Pertusa Mataix, José Salvador García Morillo

引用次数: 0

Should neuramindase be included in future flu vaccines? 未来的流感疫苗中是否应该包括神经氨酸酶？

Medicina clinica (English ed.) Pub Date : 2026-03-01 Epub Date: 2026-03-20 DOI: 10.1016/j.medcle.2026.107305

Jordi Reina

引用次数: 0

Chronic cough as a disease: A mechanism-based framework for diagnosis and management 慢性咳嗽作为一种疾病：基于机制的诊断和管理框架

Medicina clinica (English ed.) Pub Date : 2026-02-01 Epub Date: 2026-03-13 DOI: 10.1016/j.medcle.2026.107289

Miguel Jiménez-Gómez

{"title":"Chronic cough as a disease: A mechanism-based framework for diagnosis and management","authors":"Miguel Jiménez-Gómez","doi":"10.1016/j.medcle.2026.107289","DOIUrl":"10.1016/j.medcle.2026.107289","url":null,"abstract":"<div><div>Chronic cough (CC) has traditionally been attributed to asthma, rhinosinusitis, and gastroesophageal reflux disease. Yet in many patients, symptoms persist despite targeted treatment, revealing a mismatch between clinical need and current strategies.</div><div>A new paradigm has emerged: refractory and unexplained CC are increasingly recognized as manifestations of cough hypersensitivity syndrome. Diagnosis should follow a lean pathway emphasizing focused history, exclusion of red flags, essential baseline tests, and addressing treatable traits. Recognition of hypersensitivity features (allotussia, hypertussia, laryngeal paresthesia) is supported by validated tools such as the CHQ and TOPIC. Severity assessment requires integrating objective cough counts with robust patient-reported outcomes (MCSQ, CSD, LCQ, CQLQ), which capture clinical burden and guide referral.</div><div>Management should be mechanism-based: early access to multimodal speech therapy, judicious neuromodulators, and emerging peripherally targeted therapies such as P2X3 antagonists.</div><div>Establishing CC as a disease entity is essential to align research, regulation, and care with patient suffering.</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"166 2","pages":"Article 107289"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coral dermatitis 珊瑚皮炎

Medicina clinica (English ed.) Pub Date : 2026-02-01 Epub Date: 2026-03-13 DOI: 10.1016/j.medcle.2026.107266

Pablo Balado-Simó, Lluís Corbella-Bagot

引用次数: 0

Appropriateness criteria in the request for carotid ultrasonography. A multicentre study 颈动脉超声检查要求的适当标准。多中心研究

Medicina clinica (English ed.) Pub Date : 2026-02-01 Epub Date: 2026-03-05 DOI: 10.1016/j.medcle.2026.107346

Pedro Armario , Sergi Bellmunt , José Luis del Cura Rodriguez , Carlos Jiménez Zapater , Ignasi J. Gich , Pere Roure , Eva Fernandez Canabal , Carolina Requeijo , on behalf of the members of the MAPAC Research Network

{"title":"Appropriateness criteria in the request for carotid ultrasonography. A multicentre study","authors":"Pedro Armario , Sergi Bellmunt , José Luis del Cura Rodriguez , Carlos Jiménez Zapater , Ignasi J. Gich , Pere Roure , Eva Fernandez Canabal , Carolina Requeijo , on behalf of the members of the MAPAC Research Network","doi":"10.1016/j.medcle.2026.107346","DOIUrl":"10.1016/j.medcle.2026.107346","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study was to analyse appropriateness criteria in the request for carotid ultrasonography and to evaluate its association with the finding of a significative carotid stenosis.</div></div><div><h3>Patients and methods</h3><div>This was an observational, prospective, analytical, multicentre study. Consecutive adult patients (>18 years of age) who were scheduled for carotid ultrasound were included. Carotid ultrasound requests were made by the various departments of the participating hospitals and by primary care. Urgent indications were excluded. The reasons for the request and the results of the examinations were recorded. Appropriateness criteria of carotid ultrasonography were determined taking into account recommendations from the literature and clinical practice guidelines. A bivariate and multivariate analysis were performed to determine patient factors related to the appropriateness of requests.</div></div><div><h3>Results</h3><div>A total of 268 patients were included, with a mean age of 69.1 (SD 12) years, 34.3% women. Most requests were classified as adequate (65.3%; 95% CI 59.3–71.0), while the percentage of inadequate requests, according to previously established criteria, was 31.7% (95% CI 26.2–37.7). The prevalence of significant stenosis in inappropriate requests was very low (1.2%). In the bivariate analysis, the factors associated with significant carotid stenosis (≥50%) were age, high blood pressure, and dyslipidaemia. When all three variables were included in the multivariate model, only dyslipidaemia was significant: OR 5.47 (95% CI 2.7–11.0).</div></div><div><h3>Conclusions</h3><div>32% of carotid ultrasonography requests were inappropriate, with a very low prevalence.</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"166 2","pages":"Article 107346"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Streptococcus pyogenes meningitis 化脓性链球菌脑膜炎

Medicina clinica (English ed.) Pub Date : 2026-02-01 Epub Date: 2026-03-13 DOI: 10.1016/j.medcle.2026.107299

José Pedro Vinhal, Nuno Prucha Leite, Elsa Sousa

引用次数: 0

Role of ultrasonography in pediatric infectious diseases 超声检查在小儿感染性疾病中的作用

Medicina clinica (English ed.) Pub Date : 2026-02-01 Epub Date: 2026-03-04 DOI: 10.1016/j.medcle.2026.107323

Ecatherine Rodríguez Urteaga , Susana Viver Gómez

{"title":"Role of ultrasonography in pediatric infectious diseases","authors":"Ecatherine Rodríguez Urteaga , Susana Viver Gómez","doi":"10.1016/j.medcle.2026.107323","DOIUrl":"10.1016/j.medcle.2026.107323","url":null,"abstract":"<div><div>Infectious diseases remain a leading cause of pediatric consultations despite significant advances in their prevention and treatment. Clinical ultrasound has emerged as a valuable diagnostic tool in the pediatric setting due to its non-ionizing nature, the absence of need for sedation, its feasibility at the point of care, and its safety, reproducibility, and current availability.</div><div>In this article, we review pediatric infectious conditions in which clinical ultrasound contributes significantly to diagnosis, follow-up, and clinical decision-making. This is a narrative review based on both the available evidence and clinical experience regarding the role of ultrasound in pediatric infectious pathology.</div><div>Ultrasound is useful in the vast majority of pediatric infectious diseases, including respiratory infections (pneumonia, bronchiolitis), cutaneous and musculoskeletal infections (cellulitis, myositis, abscesses, osteomyelitis, arthritis), abdominal infections (appendicitis, mesenteric adenitis, intra-abdominal abscesses), urinary tract infections (pyelonephritis, renal abscess), cervical infections (adenitis, deep neck abscesses, parotitis), and genital infections (epididymitis, orchitis, scrotal abscesses). It allows the identification of characteristic findings in each condition, with good clinical and radiological correlation. Ultrasound also aids in drainage procedures, helps avoid unnecessary invasive interventions, and facilitates the monitoring of patient progress.</div><div>Point-of-care ultrasound (POCUS) has become a key tool in the diagnosis, management, and follow-up of pediatric infections.</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"166 2","pages":"Article 107323"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0