Medicina clinica (English ed.)最新文献_第10页

Bisalbuminemia 双白蛋白血症

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2023.12.027

Antonio Rosales-Castillo

引用次数: 0

Pulmonary and mediastinal nocardiosis due to lymph node involvement 淋巴结受累导致的肺部和纵隔线虫病

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2024.07.005

Yanira Chuquimia Mendoza, Silvia García García, Javier Juan García

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Clinico-pathological evaluation of tumor budding in the oncological progression of colorectal cancer 结直肠癌肿瘤进展过程中肿瘤出芽的临床病理学评估

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2024.07.004

Pietro Giovanni Giordano , Ana Gabriela Díaz Zelaya , Yari Yuritzi Aguilera Molina , Nestor Orlando Taboada Mostajo , Yelene Ajete Ramos , Ricardo Ortega García , Esteban Peralta de Michelis , Juan Carlos Meneu Díaz

{"title":"Clinico-pathological evaluation of tumor budding in the oncological progression of colorectal cancer","authors":"Pietro Giovanni Giordano , Ana Gabriela Díaz Zelaya , Yari Yuritzi Aguilera Molina , Nestor Orlando Taboada Mostajo , Yelene Ajete Ramos , Ricardo Ortega García , Esteban Peralta de Michelis , Juan Carlos Meneu Díaz","doi":"10.1016/j.medcle.2024.07.004","DOIUrl":"10.1016/j.medcle.2024.07.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Tumor Budding (TB), defined as the presence of individual neoplastic cells or isolated groups of up to 4 cells at the front of tumor invasion, has become an adverse prognostic marker in colorectal cancer (CRC) in recent decades. The prognostic impact of TB in CRC remains not clearly defined and histological methods for its evaluation vary depending on the center. The objective of this study is to investigate the association between TB and CRC, in terms of oncological evolution and pathological stage.</p></div><div><h3>Methods</h3><p>A retrospective observational study was conducted, including patients undergoing curative oncological surgery for CRC between January 2017 and December 2022. The effects of TB on disease-free survival (DFS) and overall survival (OS) were evaluated according to the Kaplan-Meier curves.</p></div><div><h3>Results</h3><p>In 78 cases TB was described in the pathology report. TB was present in 56 patients (71.8%), divided into the following categories: low grade in 22 (39.3%), intermediate grade in 17 (30.4%) and high grade in 17 (30.4%). The proportion of patients who presented lymph node metastases, lympho-vascular and perineural invasion was significantly higher in patients with TB (26.8% vs 0%, <em>P</em> = .008; 41.1% vs 4.5%, <em>P</em> = .002; 16.1% vs 0% <em>P</em> = .054; respectively). DFS was 86.3% in low-grade TB, 75.3% in intermediate-grade TB, and 70.3% in high-grade TB. Cases with intermediate and high grade were associated with a shorter OS compared to the low grade group (93.7% and 75.4% vs 100% <em>P</em> = .012, respectively).</p></div><div><h3>Conclusion</h3><p>These results suggest that TB expression may be a useful risk factor as a prognostic factor for the detection of lymph node metastasis, local recurrence, and distant metastasis in CRC.</p></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"163 4","pages":"Pages 159-166"},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142099685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vasospasm due to ingestion of a combination of psychoactive substances: A case study 摄入多种精神活性物质导致血管痉挛：病例研究

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2024.07.002

Isabel Cristina Torres-Patiño , Mónica Fernandes-Pineda , Sebastián Ayala-Zapata

引用次数: 0

Plasmacytoma of the maxillary sinus in a patient with refractory multiple myeloma 一名难治性多发性骨髓瘤患者的上颌窦浆细胞瘤

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2023.12.028

Miguel Antonio Lasheras-Pérez, Ignacio Torres-Navarro, Javier López-Davia

引用次数: 0

Endobronchial leiomyoma in a patient of 19 years 一名 19 岁患者的支气管内膜良性肌瘤

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2024.02.013

Laura Martín-Biel, María Aguado-Agudo, Andrea Carilla-Sanromán

引用次数: 0

Medical death certificate, need for the electronic medical certificate and its benefits for public health 死亡医学证明书、电子医学证明书的必要性及其对公共卫生的益处

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2024.04.009

Rafael Teijeira Alvarez , Rafael Bañón González , Sonsoles Castro Herranz , Conchi Moreno Iribas

引用次数: 0

Classification tree obtained by artificial intelligence for the prediction of heart failure after acute coronary syndromes 人工智能预测急性冠状动脉综合征后心力衰竭的分类树

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2024.01.038

Alberto Cordero , Vicente Bertomeu-Gonzalez , José V. Segura , Javier Morales , Belén Álvarez-Álvarez , David Escribano , Moisés Rodríguez-Manero , Belén Cid-Alvarez , José M. García-Acuña , José Ramón González-Juanatey , Asunción Martínez-Mayoral

{"title":"Classification tree obtained by artificial intelligence for the prediction of heart failure after acute coronary syndromes","authors":"Alberto Cordero , Vicente Bertomeu-Gonzalez , José V. Segura , Javier Morales , Belén Álvarez-Álvarez , David Escribano , Moisés Rodríguez-Manero , Belén Cid-Alvarez , José M. García-Acuña , José Ramón González-Juanatey , Asunción Martínez-Mayoral","doi":"10.1016/j.medcle.2024.01.038","DOIUrl":"10.1016/j.medcle.2024.01.038","url":null,"abstract":"<div><h3>Background</h3><p>Coronary heart disease is the leading cause of heart failure (HF), and tools are needed to identify patients with a higher probability of developing HF after an acute coronary syndrome (ACS). Artificial intelligence (AI) has proven to be useful in identifying variables related to the development of cardiovascular complications.</p></div><div><h3>Methods</h3><p>We included all consecutive patients discharged after ACS in two Spanish centers between 2006 and 2017. Clinical data were collected and patients were followed up for a median of 53 months. Decision tree models were created by the model-based recursive partitioning algorithm.</p></div><div><h3>Results</h3><p>The cohort consisted of 7,097 patients with a median follow-up of 53 months (interquartile range 18–77). The readmission rate for HF was 13.6% (964 patients). Eight relevant variables were identified to predict HF hospitalization time: HF at index hospitalization, diabetes, atrial fibrillation, glomerular filtration rate, age, Charlson index, hemoglobin, and left ventricular ejection fraction. The decision tree model provided 15 clinical risk patterns with significantly different HF readmission rates.</p></div><div><h3>Conclusions</h3><p>The decision tree model, obtained by AI, identified 8 leading variables capable of predicting HF and generated 15 differentiated clinical patterns with respect to the probability of being hospitalized for HF. An electronic application was created and made available for free.</p></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"163 4","pages":"Pages 167-174"},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142099686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinal venous occlusion and its association with atherosclerotic vascular disease 视网膜静脉闭塞及其与动脉粥样硬化性血管疾病的关系

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2024.07.003

María Larrousse Morellón , Yéssica López Loureiro , Susana Ruiz Bilbao

引用次数: 0

Xanthogranulomatous pyelonephritis: “Bear's paw sign” 黄疽性肾盂肾炎："熊掌征

Medicina clinica (English ed.) Pub Date : 2024-08-30 DOI: 10.1016/j.medcle.2023.11.044

Gökhan Tonkaz , Mehmet Tonkaz , Duygu Erkal Tonkaz , Mutlu Ay , Rüstem Berhan Pirimoğlu

引用次数: 0