Medicina clinica (English ed.)最新文献

{"title":"3-Hydroxy-3-methylglutaryl coenzyme A lyase deficiency and type 2 diabetes mellitus presenting in adulthood","authors":"Óscar Porto Fuentes , Francisco Pita Gutiérrez , Álvaro Hermida Ameijeiras","doi":"10.1016/j.medcle.2025.106925","DOIUrl":"10.1016/j.medcle.2025.106925","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 10","pages":"Article 106925"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteoporosis in premenopausal women","authors":"Pilar Peris","doi":"10.1016/j.medcle.2025.106940","DOIUrl":"10.1016/j.medcle.2025.106940","url":null,"abstract":"<div><div>The development of osteoporosis and fractures in young premenopausal women is infrequent and is usually associated with secondary causes of osteoporosis. Therefore, it is recommendable to perform a clinical evaluation and a thorough laboratory study searching for possible causes of bone loss in these patients. Treatment depends on the cause of osteoporosis and the associated processes as well as the future gestational desire of the patient, all of which should be taken into account when evaluating the most adequate diagnostic and the therapeutic approach in these patients.</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 10","pages":"Article 106940"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoimmune encephalitis and sensory ganglionopathy associated to primary Sjögren’s disease","authors":"Alicia Viñas Barros ,&nbsp;Esteban Fernando Noroña Vásconez ,&nbsp;Andrea Viñas Barros","doi":"10.1016/j.medcle.2025.106932","DOIUrl":"10.1016/j.medcle.2025.106932","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 10","pages":"Article 106932"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beri-beri: A rare and reversible cause of heart failure","authors":"Daniel Arnés-García,&nbsp;Elena Zamorano-García,&nbsp;Isabel Gallego-Romero","doi":"10.1016/j.medcle.2025.106893","DOIUrl":"10.1016/j.medcle.2025.106893","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 10","pages":"Article 106893"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic otitis media","authors":"Francisco Larrosa ,&nbsp;Laura Pujol ,&nbsp;Elena Hernández-Montero","doi":"10.1016/j.medcle.2025.106915","DOIUrl":"10.1016/j.medcle.2025.106915","url":null,"abstract":"<div><div>Chronic otitis media, defined as persistent or recurrent inflammation of the middle ear mucosa, is a frequent entity in primary and secondary care. This disease causes otorrhea and hearing loss that significantly affect the quality of life of patients.</div><div>In recent years, there have been new developments in its diagnosis, prevention and treatment. In this last aspect, pharmacological treatment, surgical techniques and hearing rehabilitation through implants have shown significant advances. On the other hand, chronic otitis media complications continue to occur in emergency services and have to be kept in mind because of their potential seriousness.</div><div>The objective of this work is to offer the reader an update in chronic otitis media, so it may help improving the care of affected patients.</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 10","pages":"Article 106915"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute myocarditis in Shoshin disease","authors":"Juan Manuel Serrano Marcos,&nbsp;José Antonio Fernández-Sánchez,&nbsp;Lucia Carnero Montoro","doi":"10.1016/j.medcle.2025.106919","DOIUrl":"10.1016/j.medcle.2025.106919","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 10","pages":"Article 106919"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Independent predictors of functional loss and refractures in patients with femur fracture: Follow-up at 6 and 18 months in a Fracture Liaison Service","authors":"Teresa Casanova Querol ,&nbsp;Dacia Cerdà Gabaroi ,&nbsp;José María Santiago Bautista ,&nbsp;Joan Girós Torres ,&nbsp;Ramon Miralles Basseda ,&nbsp;Montse Martín-Baranera","doi":"10.1016/j.medcle.2024.11.017","DOIUrl":"10.1016/j.medcle.2024.11.017","url":null,"abstract":"<div><h3>Background</h3><div>In elderly patients hospitalized for a femur fracture, this study aimed to evaluate the functional evolution, and to estimate the incidence of second fractures at 6 and 18 months after hospital discharge.</div></div><div><h3>Patients and methods</h3><div>A longitudinal prospective study was designed at an Orthogeriatric Unit after implementing a Fracture Liaison Service (FLS). The variables collected included the baseline demographic and clinical characteristics of the patients, and the outcome variables on discharge, at 6 and 18 months of follow-up. Logistic regressions models were applied to identify independent predictors of functional evolution.</div></div><div><h3>Results</h3><div>478 patients were admitted. Independent predictors of functional loss at follow-up were institutionalisation, severe dependence either prior to and on discharge, delirium, protein malnutrition, prior acute myocardial infarction, GFR<!--> <!-->&lt;<!--> <!-->30<!--> <!-->ml/min/1.73<!--> <!-->m² and not receiving treatment for osteoporosis on discharge. Patients attending follow-up appointments presented improved compliance with osteoporosis treatment both at 6 and 18 months. A lower number of 2nd fractures were recorded at 18 months for patients who attended their appointments (4.8% vs 12.1%, <em>p</em> <!-->=<!--> <!-->0.01). At 6 and 18 months follow-up, a lower rate of readmission was recorded (7% vs 15.3%, <em>p</em> <!-->=<!--> <!-->0.006), (9.6% vs 25.6%, <em>p</em> <!-->&lt;<!--> <!-->0.0001), respectively.</div></div><div><h3>Conclusions</h3><div>The independent predictors of functional loss at 6 and 18 months were institutionalisation, severe dependence either prior to and on discharge, delirium, protein malnutrition, prior acute myocardial infarct, GFR<!--> <!-->&lt;<!--> <!-->30<!--> <!-->ml/min/1.73<!--> <!-->m² and not receiving treatment for osteoporosis on discharge. A lower incidence of refractures, a lower readmission rate and a better treatment compliance were observed in patients attending follow-up visits.</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 9","pages":"Pages 451-460"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-FDG PET/CT in systemic autoimmune diseases and related disorders","authors":"Ricardo Blanco ,&nbsp;Javier Loricera","doi":"10.1016/j.medcle.2025.01.006","DOIUrl":"10.1016/j.medcle.2025.01.006","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 9","pages":"Pages 487-490"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatic phenomena associated with SARS-CoV-2: Acute liver injury, autoimmune hepatitis and post-vaccination","authors":"Roberto Pertusa Mataix ,&nbsp;José Salvador García Morillo ,&nbsp;José Manuel Sousa Martín","doi":"10.1016/j.medcle.2024.12.007","DOIUrl":"10.1016/j.medcle.2024.12.007","url":null,"abstract":"<div><div>The infection with SARS-CoV-2, primarily recognized for its respiratory effects, reveals itself as a multifaceted clinical phenomenon, extending beyond the pulmonary realm. Accompanied by gastrointestinal, neurological, thromboembolic, cardiovascular, and immune-related manifestations, the complexity of the systemic repercussions of the disease becomes apparent. Genetic predisposition is a significant factor in the development of autoimmune hepatitis, as both viruses, such as SARS-CoV-2, and drugs, including vaccines, can act as triggers in genetically susceptible individuals. A profound understanding of these mechanisms is essential to effectively address the clinical complexity of SARS-CoV-2 infection.</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 9","pages":"Pages 491-498"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant pulmonary hydatid cyst","authors":"Yener Aydin,&nbsp;Ali Bilal Ulas,&nbsp;Atilla Eroglu","doi":"10.1016/j.medcle.2024.11.020","DOIUrl":"10.1016/j.medcle.2024.11.020","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 9","pages":"Page 513"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}