Andrea Ruberti , Luis Ortega-Paz , Salvatore Brugaletta , on behalf of the CV COVID-19 Registry Investigators
{"title":"Which patients need thromboprophylaxis for venous thromboembolism prevention after hospitalization due to COVID-19? A sub-analysis from the CV COVID-19 registry","authors":"Andrea Ruberti , Luis Ortega-Paz , Salvatore Brugaletta , on behalf of the CV COVID-19 Registry Investigators","doi":"10.1016/j.medcle.2024.10.022","DOIUrl":"10.1016/j.medcle.2024.10.022","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 7","pages":"Pages 380-381"},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143769080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carmen Sánchez-Bacaicoa , Sergio Rico-Martin , Clara Costo-Muriel , Eduardo Ortega-Collazos , Marta Sánchez-Lozano , Marisol Sánchez-Bacaicoa , Javier Galán-González , Julián F. Calderón-García , Juan Francisco Sánchez Muñoz-Torrero
{"title":"Carotid Plaque-Burden scale and outcomes: A real-life study","authors":"Carmen Sánchez-Bacaicoa , Sergio Rico-Martin , Clara Costo-Muriel , Eduardo Ortega-Collazos , Marta Sánchez-Lozano , Marisol Sánchez-Bacaicoa , Javier Galán-González , Julián F. Calderón-García , Juan Francisco Sánchez Muñoz-Torrero","doi":"10.1016/j.medcle.2024.10.020","DOIUrl":"10.1016/j.medcle.2024.10.020","url":null,"abstract":"<div><h3>Background</h3><div>The value of carotid ultrasound in real-world practice remains controversial. We investigated the outcomes of people with vascular risk factors according to an easy carotid-plaque burden scale (CPB-scale). Predictive yield of the addition CPB-scale to ESC-SCORE2 (CPB-SCORE2 table) was assessed.</div></div><div><h3>Methods</h3><div>A cohort of participants without preexisting cardiovascular disease (CVD) was evaluated for clinical outcomes according to the number of plaques by segment. The usefulness of the CPB-SCORE2 table was investigated.</div></div><div><h3>Results</h3><div>A total of 1004 patients were followed for a mean of 12.5 years for major adverse cardiovascular events (MACEs) and death. The CPB-scale was independently associated with MACEs; compared to those in the low-risk group, the corresponding adjusted hazard ratios (95% confidence intervals) for MACEs among the intermediate and high-risk groups were 13.1 (4.87–35.5) and 19.4 (7.27–51.9), respectively. Similarly, the risk of death was greater for participants stratified as high-risk than for those in the low-risk group (adjusted HR 3.36 [1.58–7.15]). According to our CPB-SCORE2 table, 149 of 178 (84%) CV events were detected in the high-risk group and exhibited greater sensitivity than did the SCORE2 Table, 84%; vs. 62%; but slightly less specificity, 62%; vs. 68%. Our table shows the improved performance of SCORE2; <em>c</em>-statistics: 0.74 vs. 0.68; <em>p</em> <!--><<!--> <!-->0.001 for net reclassification index and integrated discrimination index.</div></div><div><h3>Conclusions</h3><div>A simple prognostic CPB-scale was strongly associated with the long-term risk of developing a first MACE and all-cause death. Adding the CPB-scale to the SCORE2 may improve risk prediction with easy applicability in clinical practice.</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 7","pages":"Pages 325-333"},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Decisions at the end of life in health professionals","authors":"Yanira Aranda Rubio , Beatriz Corrales González","doi":"10.1016/j.medcle.2024.11.013","DOIUrl":"10.1016/j.medcle.2024.11.013","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 9","pages":"Pages 504-505"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Manuel Aragón González, Nieves Romero Rodríguez, José Francisco Díaz Fernández
{"title":"Acute coronary syndrome due to coronary aneurysm thrombosis as a late complication of Kawasaki disease","authors":"Juan Manuel Aragón González, Nieves Romero Rodríguez, José Francisco Díaz Fernández","doi":"10.1016/j.medcle.2024.11.015","DOIUrl":"10.1016/j.medcle.2024.11.015","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 9","pages":"Pages 509-510"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David González Falcón , Leticia Gómez-Sánchez , Marta Gómez-Sánchez , Emiliano Rodríguez-Sánchez , Olaya Tamayo-Morales , Cristina Lugones-Sánchez , Susana González-Sánchez , Moises Diaz , Manuel A. Gómez-Marcos , on behalf of the EVA Study Investigators
{"title":"Evolution of arterial stiffness and association with cardiovascular risk factors in the Spanish population. Follow-up to the study EVA","authors":"David González Falcón , Leticia Gómez-Sánchez , Marta Gómez-Sánchez , Emiliano Rodríguez-Sánchez , Olaya Tamayo-Morales , Cristina Lugones-Sánchez , Susana González-Sánchez , Moises Diaz , Manuel A. Gómez-Marcos , on behalf of the EVA Study Investigators","doi":"10.1016/j.medcle.2025.03.004","DOIUrl":"10.1016/j.medcle.2025.03.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>To analyse the increase of arterial stiffness over a five-year period and its relationship with cardiovascular risk factors and sex-based differences in a Spanish population without cardiovascular disease.</div></div><div><h3>Methods</h3><div>Longitudinal study. Analysis of the increase in arterial stiffness measures evaluated with <em>SphygmoCor</em> and <em>Vasera</em> of 480 subjects followed for 5 years of the 501 subjects included in the baseline evaluation, selected through random sampling stratified by age and sex, mean age of 55.9 years, 50.3% women.</div></div><div><h3>Results</h3><div>Increases per year: carotid-femoral pulse wave velocity (cf-PWV), 0.22 (SD 0.36) m/sec, brachial-ankle pulse wave velocity (ba-PWV), 0.18 (SD 0.30) m/sec, Cardio-Ankle Vascular Index (CAVI), 0.04 (SD 0.18) and Central Augmentation Index (CAI), 0.38 (SD 2.66). Multiple regression, increases in cf-PWV and ba-PWV showed an association with mean arterial pressure in global (β = 0.02; β = −0.02) and in men (β = 0.02; β = −0.03). In women, increases in ba-PWV and CAVI showed a negative association with BMI (β = −0.06; β = −0.03).</div></div><div><h3>Conclusions</h3><div>The four measures of RA increase over five years globally and by sex. These increases differ according to the measure used, age, sex and associated CRF. Hypertensive people has greater increases in ba-PWV in global and by sex. The average blood pressure is associated with increases in cf-PWV and ba-PWV in global and in men. BMI is negatively associated with increases in ba-PWV and CAVI in women.</div><div>Study registered at ClinicalTrials.gov. (<span><span>NCT02623894</span><svg><path></path></svg></span>).</div></div>","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 9","pages":"Pages 461-469"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patricia de Miguel Mancebo, Leire Villalonga Lopez-Uribarri, David Ruiz-Clavijo García
{"title":"Intestinal intussusception secondary to colon lipoma: A rare cause of gastrointestinal bleeding","authors":"Patricia de Miguel Mancebo, Leire Villalonga Lopez-Uribarri, David Ruiz-Clavijo García","doi":"10.1016/j.medcle.2024.10.032","DOIUrl":"10.1016/j.medcle.2024.10.032","url":null,"abstract":"","PeriodicalId":74154,"journal":{"name":"Medicina clinica (English ed.)","volume":"164 9","pages":"Page 512"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}