Le Mali medical最新文献_第4页

[Evaluation Of Dosage Errors During Mass Treatment Campaigns Targeting Lymphatic Filariasis And Onchocerciasis In The Health Districts Of Bougouni And Kolondièba, Mali]. [在马里布古尼和科隆迪孔特巴卫生区针对淋巴丝虫病和盘尾丝虫病的大规模治疗运动中剂量错误的评估]。

Le Mali medical Pub Date : 2025-05-13 eCollection Date: 2025-05-01 DOI: 10.4314/mml.v40i1.4

Mahamoud Mahamadou Koureichi, Idrissa Sangare, Moussa Sangaré, Abdoul Fatao Diabaté, Ilo Dicko, Lamine Diarra, Oumar Coulibaly, Fatoumata Traoré, Binta Sall, Djadié Tanapo, Sékou Thera, Abdoul Karim Koné, Karim Dembélé, Michel Emmanuel Coulibaly, Lamine Soumaoro, Siaka Yamoussa Coulibaly, Salif Sériba Doumbia, Modibo Keita, Abdallah Amadou Diallo, Aboubacar Alassane Oumar, Housseini Dolo, Yaya Ibrahim Coulibaly

{"title":"[Evaluation Of Dosage Errors During Mass Treatment Campaigns Targeting Lymphatic Filariasis And Onchocerciasis In The Health Districts Of Bougouni And Kolondièba, Mali].","authors":"Mahamoud Mahamadou Koureichi, Idrissa Sangare, Moussa Sangaré, Abdoul Fatao Diabaté, Ilo Dicko, Lamine Diarra, Oumar Coulibaly, Fatoumata Traoré, Binta Sall, Djadié Tanapo, Sékou Thera, Abdoul Karim Koné, Karim Dembélé, Michel Emmanuel Coulibaly, Lamine Soumaoro, Siaka Yamoussa Coulibaly, Salif Sériba Doumbia, Modibo Keita, Abdallah Amadou Diallo, Aboubacar Alassane Oumar, Housseini Dolo, Yaya Ibrahim Coulibaly","doi":"10.4314/mml.v40i1.4","DOIUrl":"10.4314/mml.v40i1.4","url":null,"abstract":"The aim of this study was to assess dosing errors when administering ivermectin (IVM) according to height, using a measuring cup with reference to the manufacturer's recommended dosage according to weight. For this purpose, a secondary analysis of the database of a community trial conducted in the health districts of Bougouni and Kolondièba was carried out. This made it possible to assess the proportions of participants who received underestimated doses, and to identify the factors associated with underestimation of IVM dose when using the toise. In all, 8.6% of participants (258/3011) received an underestimated dose. Of these, the most represented age group was the under-10s, with 63.18% (163/258), and the over-20s, with 25.19% (65/258). There was a significant correlation between missing dose quantities and height (r=17.1%, p=0.00593), as well as age (r=14.2%, p=0.02227). Participants under 10 years of age were 2.62 times (OR= 2.62; 95% CI: 1.58 - 4.43) more likely to be under-dosed than those aged 10 and over. Having a height of 120 cm or more made a participant 22.5 times (OR= 22.5; 95% CI: 13.5 - 38.4) more likely to be underdosed compared to those with a height ranging from 90 to 119 cm. These results suggest that it is crucial to make adequate adjustments to ensure a favorable response in CT participants in areas receiving MVI.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 1","pages":"21-30"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12378588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Locations Of Tuberculosis In HIV-infected Patients Hospitalized In The Infectious Diseases Department Of The Sylvanus OLYMPIO University Hospital Center In Lomé]. [在洛洛伊市希尔瓦努斯奥林匹奥大学医院中心传染病科住院的hiv感染患者的结核病地点]。

Le Mali medical Pub Date : 2025-05-13 eCollection Date: 2025-05-01 DOI: 10.4314/mml.v40i1.2

Lidaw Déassoua Bawe, Awèréou Kotossso, Bawoubadi Abaltou, Akouda Akessiwe Patassi, Majesté Ihou Watéba

{"title":"[Locations Of Tuberculosis In HIV-infected Patients Hospitalized In The Infectious Diseases Department Of The Sylvanus OLYMPIO University Hospital Center In Lomé].","authors":"Lidaw Déassoua Bawe, Awèréou Kotossso, Bawoubadi Abaltou, Akouda Akessiwe Patassi, Majesté Ihou Watéba","doi":"10.4314/mml.v40i1.2","DOIUrl":"10.4314/mml.v40i1.2","url":null,"abstract":"Introduction: Tuberculosis (TB) still remains a major public health problem in developing countries, particularly among patients infected with the human immunodeficiency virus (HIV). The main objective was to describe the different locations of tuberculosis in HIV-infected and immunocompromised patients.Methods: This was a 24-month retrospective and descriptive study, from January 1, 2020 to December 31, 2021 in the Infectious and Tropical Diseases department of the Sylvanus OLYMPIO University Hospital Center in Lomé, focusing on co-infected patients TB/HIV hospitalized.Results: Two hundred and eighty-nine patients were hospitalized in the department during the study period, including 211 patients infected with HIV, representing a frequency of HIV infection of 73%. There were 46 TB/HIV co-infected patients, representing a frequency of 21.8%. Their average age was 43.08 years with a male predominance (n=27). Four patients had a history of tuberculosis, including 1 patient in whom anti-tuberculosis treatment was not completed. There were 31 cases of pulmonary tuberculosis and 24 cases of extrapulmonary tuberculosis. Nine patients presented with multifocal tuberculosis. The average CD4 count was 151.2 cells/µl with extremes of 2 cells/µl to 495 cells/µl. Forty-five patients received first-line anti-tuberculosis treatment and 1 patient was treated with the second line.Conclusion: Pulmonary localization of tuberculosis predominates in TB/HIV co-infected patients.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 1","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12378591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Childhood Constipation In A General Pediatrics Unit In Bamako]. [巴马科普通儿科中的儿童便秘问题]。

Le Mali medical Pub Date : 2024-01-01

K Sacko, D Konaté, F Traoré, B Maiga, K Traoré, H Konaré, F L Diakité, G Bah, A Dembelé, E Cissé, A Touré, A Doumbia, P Togo, A K Doumbia, O Coulibaly, M Traoré, L Maiga, I Ahmadou, Y A Coulibaly, H Diall, A Sangaré, A A Diakité, F T Dicko, M Sylla, B Togo

{"title":"[Childhood Constipation In A General Pediatrics Unit In Bamako].","authors":"K Sacko, D Konaté, F Traoré, B Maiga, K Traoré, H Konaré, F L Diakité, G Bah, A Dembelé, E Cissé, A Touré, A Doumbia, P Togo, A K Doumbia, O Coulibaly, M Traoré, L Maiga, I Ahmadou, Y A Coulibaly, H Diall, A Sangaré, A A Diakité, F T Dicko, M Sylla, B Togo","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Constipation is a symptom that corresponds to an anomaly of the stools or their elimination: they are too bulky or too hard, too rare, or their elimination is painful, even incomplete.Objective: was to determine the frequency, the contributing factors, the signs and the therapeutic methods of constipation in children in the pediatric department of the CHU Gabriel Touré.Patients and method: This was a descriptive cross-sectional study with prospective collection from April 1, 2019 to January 31, 2020. All patients aged 0 to 15 who consulted in the pediatric department for constipation and responding to the Rome IV criteria.Result: We registered 75 patients. The hospital frequency of 0.23%. The age group from one month to two years represented 61.3% of the patients, the average age was 27.7 +/- 43 months. The male gender predominated with 58.7%. Constipation alone was the most common reason for consultation with 62.6%. One stool per week was found in 77.3% of patients. Pain on defecation was found in 65.3% of patients. Constipation was functional in 69.3% of patients. Hirschsprung disease was the cause of organic constipation in 65.2% of patients. Laxatives were prescribed in 64% of patients at the consultation.Conclusion: Constipation is a frequent pathology that affects children at all ages. It is of functional origin in most case.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 1","pages":"5-10"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142712081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Epidemiological, Clinical And Therapeutic Aspects Of Childhood Asthma In The Department Of Pediatrics Of The Gabriel Touré University Hospital]. [加布里埃尔-杜尔大学医院儿科的儿童哮喘流行病学、临床和治疗方面]。

Le Mali medical Pub Date : 2024-01-01

K Sacko, L N Sidibé, K Traoré, D Konaté, B Maiga, A Dembélé, A Touré, F Traoré, H Konaré, O Coulibaly, M E Cissé, O Coulibaly, P Togo, A K Doumbia, L Maiga, A Doumbia, A Ouattara, M Traoré, Mohamed Diarra, Y A Coulibaly, T Simaga, O Coulibaly, I Ahamadou, A Sangaré, F L Diakité, A A Diakité, F Dicko, B Togo, M Sylla

{"title":"[Epidemiological, Clinical And Therapeutic Aspects Of Childhood Asthma In The Department Of Pediatrics Of The Gabriel Touré University Hospital].","authors":"K Sacko, L N Sidibé, K Traoré, D Konaté, B Maiga, A Dembélé, A Touré, F Traoré, H Konaré, O Coulibaly, M E Cissé, O Coulibaly, P Togo, A K Doumbia, L Maiga, A Doumbia, A Ouattara, M Traoré, Mohamed Diarra, Y A Coulibaly, T Simaga, O Coulibaly, I Ahamadou, A Sangaré, F L Diakité, A A Diakité, F Dicko, B Togo, M Sylla","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Asthma is the most common chronic disease of children. It is a leading cause of emergency room visits, hospitalization and school absenteeism. Asthma is a real public health problem. The prevalence of this disease is increasing worldwide.Patients and method: We had conducted a prospective study, among children with asthma over a period of one year, from January 2018 to December 2018.Results: We counted 105 asthmatic patients for a total of 14344 consultations, or a frequency of 0,73%. The sex ratio was 1,9, the age group 2-5 years was the most frequent, (52%), the age of the first attack was generally between 1 and 2 years, ( 75,24%). We observed that almost 22% of the attacks occurred in December (21,90%). Smoke and humidity were the main triggers. All the patients had benefited from nebulization with B 2 mimetics.Conclusion: Education of asthmatic children, their families and the establishment of standard management protocols could significantly reduce asthma-related morbidity in our countries.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 1","pages":"49-53"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142712102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Reproductive Risk Factors For Breast Cancer: A Case-Control Study]. [乳腺癌的生殖风险因素：病例对照研究]。

Le Mali medical Pub Date : 2024-01-01

M B Kané, I Téguété, F K Tounkara, S Fané, My Djiré, F M Sidibé, Y Traoré, A Togo

引用次数: 0

[Factors Associated With Neonatal Mortality In Diamare, Cameroon]. [喀麦隆迪亚玛雷新生儿死亡率的相关因素]。

Le Mali medical Pub Date : 2024-01-01

André Arsène Bita Fouda, Carnegie Christhie Dongmo Mefogouang, Angèle Pondy, Bika Claude, Noufack Zambou Gertrude, Pierre Manuel Bita Ongolo, Solange Renée Abouem, Jules Léon Owona Manga, Dieudonné Adiogo

{"title":"[Factors Associated With Neonatal Mortality In Diamare, Cameroon].","authors":"André Arsène Bita Fouda, Carnegie Christhie Dongmo Mefogouang, Angèle Pondy, Bika Claude, Noufack Zambou Gertrude, Pierre Manuel Bita Ongolo, Solange Renée Abouem, Jules Léon Owona Manga, Dieudonné Adiogo","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To estimate the neonatal mortality rate, causes and factors associated to newborn deaths in Diamaré in Cameroon.Patients and methods: It was an analytical and retrospective cross-sectional study. The period of the study was from January 1st 2018 to December 31st 2019 in 11 health facilities in Diamaré. The Chi 2 test was used to analyze factors associated to neonatal mortality.Results: A total of 208neonatal deaths out of 29,209 live births were recorded, representing a neonatal death rate of 71 per 100,000 live births. The study showed that neonatal mortality mainly occurred in the early neonatal period 178 cases (85.6%). Neonatal mortality was predominant among girls 121 cases (58.2%). The main reasons for admission linked to neonatal deaths were respiratory distress 44 (21.4%), prematurity 37 (18.0%) and fever 32 (15.5%). The factors associated with neonatal deaths were asphyxia (p=0.007) and neonatal infection (p=0.042) occurring during the ultra-early and late periods respectively.Conclusion: The neonatal mortality rate was high in Diamaré. These deaths were associated with asphyxia and neonatal infection.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 3","pages":"52-56"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Social Environment Of Female Drug Users Treated At The Abidjan Addictology And Mental Hygiene Service From January 2019 To December 2022]. [2019年1月至2022年12月在阿比让戒毒和精神卫生服务机构接受治疗的女性吸毒者的社会环境]。

Le Mali medical Pub Date : 2024-01-01

Etobo Innocent Ahounou, Brahim Samuel Traoré, Rita Ahou Aka, Estelle Kévine Gahy, Mathenin Bamba, Jean-Marie Yéo-Tenena

{"title":"[Social Environment Of Female Drug Users Treated At The Abidjan Addictology And Mental Hygiene Service From January 2019 To December 2022].","authors":"Etobo Innocent Ahounou, Brahim Samuel Traoré, Rita Ahou Aka, Estelle Kévine Gahy, Mathenin Bamba, Jean-Marie Yéo-Tenena","doi":"","DOIUrl":"","url":null,"abstract":"Context: Women's drug use is a taboo subject that remains poorly documented in our context, and the social environment plays an important role in this behaviour. The aim of this study was to investigate the social environment of female drug users treated at the Abidjan Addictology and Mental Hygiene Service (SAHM).Materials and methods: We conducted a descriptive cross-sectional study of 35 female drug users screened by urine toxicology analysis and followed up from January 2019 to December 2022 at the SAHM in Abidjan. They were recruited using non-probability, exhaustive sampling.Results: Female drug users were aged 15-20 years in 48.58% of cases and were pupils or students (51.43%). The respondents were poly-substance users (80%), dominated by cannabis (74.28%), benzodiazepines (34.28%) and cocaine (29.85%), which were used for self-therapeutic purposes (45.72%). The social environment was dominated by a poor family atmosphere (48.57%), the influence of peers (91.42%), the presence of smoking rooms close to home (57.14%) and the availability of psychoactive substances nearby (82.86%) and at affordable prices (74.28%).Conclusion: Knowledge of the social environment of female drug users is important for implementing awareness-raising and prevention measures tailored to the target population in order to combat the stigmatisation they may suffer.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 3","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142712008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Breast Cancer In Women: Prognostic Factors And Survival In The General Surgery Department At The Gabriel Touré University Hospital, Bamako]. [妇女乳腺癌：巴马科加布里埃尔-图雷大学医院普通外科的预后因素和存活率]。

Le Mali medical Pub Date : 2024-01-01

T Koné, Z Saye, A Maïga, B Y Sidibé, Amadou Traoré, I Diakité, Madiassa Konaté, H Doumbia, A Dramé, A Traoré, B T Dembélé, L Kanté, A Togo

{"title":"[Breast Cancer In Women: Prognostic Factors And Survival In The General Surgery Department At The Gabriel Touré University Hospital, Bamako].","authors":"T Koné, Z Saye, A Maïga, B Y Sidibé, Amadou Traoré, I Diakité, Madiassa Konaté, H Doumbia, A Dramé, A Traoré, B T Dembélé, L Kanté, A Togo","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: The aim of this work was to study the prognostic factors of breast cancer and their correlation with survival in women in the General Surgery Department of the Gabriel Touré CHU in Bamako.Materials and methods: This was a cohort study from January 2020 to December 2022, a period of 36 months.Results: A total of 67 patients were registered. The mean age was 47.6 ±13.3 years; the mean time to consultation was 12.7 ±11.6 months. A breast mass was palpable in 82% of cases; its mean size was 7.18 cm±3,97. It was a non-specific infiltrating ductal carcinoma in 95.52% of cases. SBR grade 3 was found in 32.84%. Advanced stages (III and IV) accounted for 77.61% of cancers. The majority of cancers (50.74%) were triple-negative subtypes. Mastectomy with axillary dissection was performed in 95.52% of patients, with significant lymph node involvement in 35.82% of cases. Targeted therapy was performed in 7.46% of cases. Post-operative follow-up was straightforward in 89.09% of cases. Overall survival was 26.30 months with a median survival of 23.86 months. SBR3 grade and triple-negative subtype were the prognostic factors that significantly influenced survival.Conclusion: Efficient management of breast cancer requires proper assessment of prognostic factors. Biomolecular factors SBR-EE and triple-negative had a strong correlation with survival.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 2","pages":"23-27"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142712068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Knowledge And Practice Attitude Of Mothers Regarding Routine Immunization, Comparative Study]. [母亲对常规免疫接种的认识和实践态度，比较研究]。

Le Mali medical Pub Date : 2024-01-01

B M Traoré, I S Goïta, M Traoré, L Cissé, K Sanogo, A Boly

{"title":"[Knowledge And Practice Attitude Of Mothers Regarding Routine Immunization, Comparative Study].","authors":"B M Traoré, I S Goïta, M Traoré, L Cissé, K Sanogo, A Boly","doi":"","DOIUrl":"","url":null,"abstract":"Background: Routine immunization is a key strategy in the prevention of vaccine-preventable diseases. The objective of the study was to assess the knowledge and attitudes of mothers regarding the practice of vaccination in rural and urban areas.Methods: This is a comparative descriptive cross-sectional study that took place in two health areas (urban and rural) over a period of three (3) months from October to December 2022. It involved mothers or guardians of children who came for routine vaccination.Results: The mean age of the women was 28.76±6.85 years in urban areas and 26.51±7.37 years in rural areas. About 72.00% and 43.00% of the women in urban and rural areas, respectively, had given a good definition of vaccination. 88.00% of women in urban areas knew at least one EPI target disease, compared to 55.00% in rural areas. Only 31.00% of women in urban areas knew the vaccination schedule, compared to 12.00% in urban areas. Majority of women in urban (97.00%) and rural (67.00%) areas found it necessary to make up for missed immunization appointments in next sessions. Majority of them considered it necessary to send their children to the health center in the event of post-immunization symptoms (urban: 80.00%, rural: 53.00%).Conclusion: A good knowledge and practice of vaccination would allow to protect children against vaccine preventable diseases.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 1","pages":"34-39"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142712111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Breast Cancer With Synchronous Metastases At The Gabriel Toure University Hospital: Frequency And Prognosis]. [加布里埃尔-图雷大学医院同步转移的乳腺癌：频率与预后]。

Le Mali medical Pub Date : 2024-01-01

B Diawara, I Téguété, F K Tounkara, F M Sidibé, S Sanogo, A Bocoum, N Mounkoro

{"title":"[Breast Cancer With Synchronous Metastases At The Gabriel Toure University Hospital: Frequency And Prognosis].","authors":"B Diawara, I Téguété, F K Tounkara, F M Sidibé, S Sanogo, A Bocoum, N Mounkoro","doi":"","DOIUrl":"","url":null,"abstract":"Breast cancer is a public health issue worldwide. One of the main causes of death due to this disease is metastasis, which is understudied in our context. Thus, the objectives of this work were to: (1) estimate the frequency of synchronous metastatic breast cancer; (2) determine the overall survival rate; and (3) identify the main factors associated with metastatic breast cancer death in Malian women.Patients and methods: We conducted a retrospective cohort study at Gabriel Touré Teaching hospital on breast cancer cases diagnosed during the period from January 1st, 2018 to August 31st, 2021. We included all pathologically confirmed of breast cancer with synchronous metastases. Descriptive statistics were used to analyze sociodemographic and clinical data. Identification of factors associated with metastatic breast cancer death was performed using univariate and multivariate Cox regression models to produce adjusted hazard ratios (AHR) with their 95% confidence intervals.Results: During the study period, a total of 231 cases of breast cancer were diagnosed in our department; among them, 60 cases were synchronous metastatic breast cancer (26%). The mean age of these cases was 45.3 ±12.1 years old. The most common histological form was non-specific infiltrating carcinoma, 55 cases (91.7%). The main metastatic sites were lung alone, 26 cases (43.3%), liver alone, 12 cases (20.0%) and 16 cases (26.6%) had more than one metastatic sites. The overall 2-year survival was less than 20%. Factor associated with the risk of death was lung metastases; AHR = 4.22 [95% CI: 1.13 - 15.79].Conclusion: Synchronous metastatic breast cancer was very common in our setting and a poor prognosis was observed in patients with lung metastasis.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"39 2","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0