Le Mali medical最新文献

[Rule Of Medical Imaging In The Diagnosis Of The Right Inferior Lobar Branch Of The Pulmonary. Artery's Agenesis At Bamako: Case Report]. 肺右下叶支的医学影像学诊断规则。巴马科动脉发育不全：病例报告。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.9

A Kouma, B M Touré, M A Camara, S Sanogo, C Sylvain, O Traoré, M Dembélé, J Dembélé, I Cissé, I Guindo, A D Keïta, S Sidibé

{"title":"[Rule Of Medical Imaging In The Diagnosis Of The Right Inferior Lobar Branch Of The Pulmonary. Artery's Agenesis At Bamako: Case Report].","authors":"A Kouma, B M Touré, M A Camara, S Sanogo, C Sylvain, O Traoré, M Dembélé, J Dembélé, I Cissé, I Guindo, A D Keïta, S Sidibé","doi":"10.4314/mml.v40i4.9","DOIUrl":"10.4314/mml.v40i4.9","url":null,"abstract":"We report a case of agenesis of the right inferior lobar branch of the pulmonary artery in the Medical Imaging Department of the Mali Hospital. The patient was a 61-year-old woman residing in Bamako and admitted to the Medical Imaging Department of the Mali Hospital. On admission, she had a history of pulmonary tuberculosis, which had been treated and cured since the age of 25, and had controlled hypertension. Clinical examination revealed a deterioration in general condition, chest pain, respiratory distress, a productive cough, decreased vocal vibrations on palpation, submatousness on percussion, and crackles in both lung fields on auscultation. A standing frontal chest X-ray revealed narrowing of the right intercostal spaces with slight collapse of the ipsilateral lower lobe, elevation of the ipsilateral diaphragmatic hemidome, and a verticalized right lower lobe vascular network. Echocardiography revealed mild dilation of the cardiac chambers. An ECG revealed left ventricular hypertrophy. Based on the echocardiography and ECG findings, a pulmonary CT angiogram was requested, which revealed agenesis of the right lower lobe branch of the pulmonary artery, left hypertrophic cardiomyopathy, hypoplasia of the right lower pulmonary vein, bilateral bronchopulmonary disease, mild hypoplasia of the right lower lobe, and mild dilation of the left arterial branch. Agenesis of the right lower lobe branch of the pulmonary artery is a rare congenital malformation. Pulmonary CT angiography plays a key role in diagnosis and ensures appropriate management.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 4","pages":"44-47"},"PeriodicalIF":0.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Acute Generalised Peritonitis Due To Post-Abortal Uterine Perforation: A Case Report From Yalgado Ouedraogo University Hospital]. 流产后子宫穿孔致急性全身性腹膜炎1例（Yalgado Ouedraogo大学医院）。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.8

Hien Dieudonné, Some Zièm, Ngoufack Kengne Dorian Valdo, Toe Rolande, Ouedraogo Emmanuel, Ouedraogo Ali

引用次数: 0

[Renal Damage In Sickle Cell Disease: The Experience Of A Sickle Cell Reference Center In Sub-Saharan Africa]. 镰状细胞病的肾损害：撒哈拉以南非洲镰状细胞参考中心的经验。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.1

Maxime Keita, Abdoul Karim Dembélé, Mariam Kanta, Ismael Kamara, Aldiouma Guindo, Saharé Fongoro, Kaya Assétou Souckho, Aissata Diebkilé Tolo, Dapa Aly Diallo

{"title":"[Renal Damage In Sickle Cell Disease: The Experience Of A Sickle Cell Reference Center In Sub-Saharan Africa].","authors":"Maxime Keita, Abdoul Karim Dembélé, Mariam Kanta, Ismael Kamara, Aldiouma Guindo, Saharé Fongoro, Kaya Assétou Souckho, Aissata Diebkilé Tolo, Dapa Aly Diallo","doi":"10.4314/mml.v40i4.1","DOIUrl":"10.4314/mml.v40i4.1","url":null,"abstract":"Introduction: renal damage, often due to impaired glomerular function, is a progressive complication associated with high mortality in sickle cell disease. Few studies report on this complication in the context of organized care in sub-Saharan Africa.Objective: to describe renal damage in sickle-cell patients attending in sickle-cell referral center in sub-Saharan Africa.Patients and methods: a descriptive and analytical study with retrospective data collection was carried out from March 2010 to March 2017, at the «Centre de Recherche et de Lutte contre la Drépanocytose» of Bamako, Mali.Results: 125 sickle cell disease patients, including 70 SS, 43 SC, 10 Sβ+thalassemics and 2 Sβ°thalassemics, distributed between 67 women and 58 men with a mean age of 33.03 ± 15.53 years, were identified. Renal damage was documented by sickle cell nephropathy (84.8%), CKD (10.4%) and hematuria (4.8%); it was significantly associated with a history of hypertension, diabetes or non-steroidal antiinflammatory drugs use (p < 0.05), but was not observed in patients with fœtal hemoglobin > 20%. Five patients (4%) were on chronic kidney dialysis.Conclusion: the precocity and high frequency of renal damage in sickle-cell patients in sub-Saharan Africa call for studies to identify the risk factors for this complication in a cohort of sickle-cell patients followed up from birth.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 4","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Chest Trauma In Bouaké (Côte d'Ivoire): Epidemiological, Clinical And CT Aspects]. [胸部创伤在bouak<s:1> (Côte d'Ivoire)：流行病学，临床和CT方面]。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.3

Bouassa Davy Melaine Kouakou, Kouamé Paul Bonfils Kouassi, Soro Malick, Eklou Akoli Baudouin Bravo-Tsri, Kesse Emile Tanoh, Allou Florent Kouadio, Brou Lambert Yao, Sara Carole Sanogo, Jean Jacques Goua, Celine Yao, Issa Konaté

{"title":"[Chest Trauma In Bouaké (Côte d'Ivoire): Epidemiological, Clinical And CT Aspects].","authors":"Bouassa Davy Melaine Kouakou, Kouamé Paul Bonfils Kouassi, Soro Malick, Eklou Akoli Baudouin Bravo-Tsri, Kesse Emile Tanoh, Allou Florent Kouadio, Brou Lambert Yao, Sara Carole Sanogo, Jean Jacques Goua, Celine Yao, Issa Konaté","doi":"10.4314/mml.v40i4.3","DOIUrl":"10.4314/mml.v40i4.3","url":null,"abstract":"Aim: Contributing to the improvement of chest trauma care.Objective: Identifying post-traumatic chest CT lesions.Materials and methods: Retrospective study conducted at the Bouaké Medical Imaging Centre from January 2019 to December 2021, i.e. over a period of three years. It involved 103 patients with chest trauma in Bouaké who underwent CT scans. Epidemiological and clinical parameters and CT scan findings were analysed.Results: The average age of patients was 33 years, with extremes of 2 and 89 years. Males predominated in 78% of cases, with a sex ratio of 3.57. In 76.3% of cases, the patients were victims of road traffic accidents (RTAs). Chest injuries were closed in the majority of cases (94%). Parietal lesions were observed in 87.4% of cases. Rib fractures accounted for 87.4%. These fractures were multiple in 70% of cases. Haemothorax, pulmonary contusion and pneumomediastinum accounted for 25.2%, 28% and 7.7% of chest injuries, respectively.Conclusion: Computed tomography is the appropriate examination for the management of chest trauma, especially in the context of multiple trauma. Rigorous technique and interpretation would ensure a comprehensive study, preventing potential injuries from being overlooked.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 4","pages":"12-17"},"PeriodicalIF":0.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Rasmussen Encephalitis, Case Report And Review Of The Literature]. [拉斯穆森脑炎病例报告及文献综述]。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.7

A S Sissoko, C Sangaré, A Touré, M Sangaré, T Coulibaly, I K Bagayogo, M Dembélé, S O Djimdé, M Sacko, S Koita, M Dramé, Th Coulibaly, G Landouré, S H Diallo, Y M Maiga

引用次数: 0

[Contribution Of Ultrasound-Guided PENG Block With Phenol In The Treatment Of Chronic Degenerative Joint Pain: Preliminary Study At Bouaké University Hospital]. 超声引导下苯酚PENG阻滞治疗慢性退行性关节痛的作用：布瓦克大学医院的初步研究。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.2

Bouassa Davy Melaine Kouakou, Achié Jean-Régis Akobe, Seri Serge Landry, Yannick Thibaut Koffi, Kouamé Paul Bonfils Kouassi, Soro Malick, Brou Lambert Yao, Ettien Jacqueline Stéphanie Kouadio, Sanogo Sara Carole, Anne Cecile Neau, Issa Konaté

{"title":"[Contribution Of Ultrasound-Guided PENG Block With Phenol In The Treatment Of Chronic Degenerative Joint Pain: Preliminary Study At Bouaké University Hospital].","authors":"Bouassa Davy Melaine Kouakou, Achié Jean-Régis Akobe, Seri Serge Landry, Yannick Thibaut Koffi, Kouamé Paul Bonfils Kouassi, Soro Malick, Brou Lambert Yao, Ettien Jacqueline Stéphanie Kouadio, Sanogo Sara Carole, Anne Cecile Neau, Issa Konaté","doi":"10.4314/mml.v40i4.2","DOIUrl":"10.4314/mml.v40i4.2","url":null,"abstract":"Objective: To evaluate the short-term efficacy and safety of ultrasound-guided phenol PENG Block for the management of chronic pain of degenerative joint origin at Bouaké University Hospital.Methods: Prospective study conducted over six months (July-December 2024), including patients (>16 years old) suffering from painful degenerative joint diseases (EN > 6/10). Epidemiological, clinical and therapeutic variables were analysed. A statistical analysis using Student's t-test (p < 0.05) assessed pain reduction after phenol PENG Block.Results: Twenty-six patients were included (mean age: 43 years). The majority were women (73.1%), who were overweight (38.5%) or obese (23%). Coxarthrosis was the most common indication (42.4%). Phenol PENG block resulted in a significant reduction in pain, with a decrease in the average EN from 8 to 2 (p = 0.00). No complications were reported.Conclusion: Ultrasound optimises the accuracy and safety of PENG block, making its use essential. The development of cooperation strategies promotes better management of this technique.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 4","pages":"6-11"},"PeriodicalIF":0.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[BRCA1 Gene's Mutations And Hereditary Breast Cancer: Genetic, Biological, And Clinical Aspects]. BRCA1基因突变与遗传性乳腺癌：遗传学、生物学和临床方面。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.10

Fatoumata Korika Tounkara, Ibrahima Téguété, Fatoumata Matokoma Sidibé, Dapa Aly Diallo

{"title":"[BRCA1 Gene's Mutations And Hereditary Breast Cancer: Genetic, Biological, And Clinical Aspects].","authors":"Fatoumata Korika Tounkara, Ibrahima Téguété, Fatoumata Matokoma Sidibé, Dapa Aly Diallo","doi":"10.4314/mml.v40i4.10","DOIUrl":"10.4314/mml.v40i4.10","url":null,"abstract":"Introduction: Hereditary breast cancer accounts for approximately 5 to 10% of all breast cancer cases. Mutations in the BRCA1 gene, which plays a central role in DNA repair and cell cycle regulation, are the main cause of these familial forms and are strongly associated with aggressive subtypes, particularly triple-negative breast cancer.Methods: A narrative literature review was conducted using biomedical databases (PubMed, Scopus, Web of Science, Google Scholar) between January 2024 and June 2025. Eligible publications addressed the genetic, biological, epidemiological, and clinical aspects of BRCA1 in hereditary breast cancer.Results: BRCA1 ensures genomic stability through its roles in DNA repair, cell cycle checkpoints, and transcriptional regulation. Most mutations are truncating or missense variants, with some reported as founder mutations (e.g., c.68_69delAG, c.5266dupC, 943ins10). Women carrying germline BRCA1 mutations have an estimated lifetime risk of 56-87% of developing breast cancer, with a strong association with aggressive molecular subtypes, especially triple-negative breast cancer.Conclusion: A comprehensive understanding of BRCA1 mutations is crucial to enhance prevention, screening, and personalized management of hereditary breast cancer. In low-resource settings, the integration of genetic testing and counseling remains a major challenge and a public health priority to reduce disparities in cancer care.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 4","pages":"48-59"},"PeriodicalIF":0.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Value Of Bone Scintigraphy To Mdp-Tc 99m In The Management Of Prostate Cancer At The Institute Of Radioisotopes Of Niamey]. [骨显像检测Mdp-Tc 99m在Niamey放射性同位素研究所前列腺癌治疗中的价值]。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.4

Djibrillou Moussa Issoufou, Maman Sani Ousmane Manzo, Yahouza Boka Tounga, Seydou Hamadou Adamou, Karimoune Mossi Oumarou, Soumana Amadou

{"title":"[Value Of Bone Scintigraphy To Mdp-Tc 99m In The Management Of Prostate Cancer At The Institute Of Radioisotopes Of Niamey].","authors":"Djibrillou Moussa Issoufou, Maman Sani Ousmane Manzo, Yahouza Boka Tounga, Seydou Hamadou Adamou, Karimoune Mossi Oumarou, Soumana Amadou","doi":"10.4314/mml.v40i4.4","DOIUrl":"10.4314/mml.v40i4.4","url":null,"abstract":"Introduction: Prostate cancer is a real public health problem. Studies have shown that 95% of deaths secondary to this cancer are due to metastases. The earlier metastases are diagnosed, the better the chances of survival.Objective: Analyze the results and show the contribution of bone scintigraphy in the management of prostate cancer in Niger.Methods: This was a retrospective descriptive and analytical study over a period of 8 years from February 09, 2014 to March 13, 2022 at the Department of Nuclear Medicine of the Institute of Radioisotopes of Niamey of patients who had undergone a bone scan as part of the management of prostate cancer.Results: The frequency of requesting bone scintigraphy concerning the prostate was 7%. The average age of our patients was 67.6 years with extremes ranging from 50 to 90 years. The most represented age group was 60 to 70 years. During the period of our study, bone scintigraphy was indicated in 93% of our patients as part of an initial assessment of prostate cancer. Urologists and oncologists were the main prescribers of this examination in 43.8% and 35.4% respectively. In our study, abnormal PSA > 20 ng/ml was predominant in 69.2%. Bone scintigraphy was abnormal in 72% (n=69) of cases. Bone lesions predominated on the axial + appendicular skeleton in 75.3% (n=52) with the most spinal injuries in 54%.Conclusion: Bone scintigraphy plays a diagnostic, therapeutic and prognostic role in prostatic cancer.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 4","pages":"18-24"},"PeriodicalIF":0.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Acute Intestinal Obstruction Of The Small Bowel By Internal Hernia In Winslow's Hiatus, Concerning Two Clinical Cases And Literature Review]. 【温斯洛氏裂孔内疝致急性小肠梗阻2例临床及文献复习】。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.6

S Pamateck, A A Doumbia, I Ahamadou, S Guindo, M Konaté, B Y Sidibe, A Samaké, D Koné, Z Saye, S Doumbia, I Darar, Z Coulibaly, L Diallo, T Koné, A Maiga, Y Ouattara, S O Traoré, A Traoré, S Koïta, B T Dembélé, A Togo

引用次数: 0

[Darier-Ferrand Dermatofibrosarcoma In Point "G" University Hospital]. [drier - ferrand皮肤纤维肉瘤在G点大学医院]。

Le Mali medical Pub Date : 2026-01-19 eCollection Date: 2025-01-01 DOI: 10.4314/mml.v40i4.5

M Ganmenon, M Sissoko, S Koita, B Togola, M Doura, S Koumare, A Togo

{"title":"[Darier-Ferrand Dermatofibrosarcoma In Point \"G\" University Hospital].","authors":"M Ganmenon, M Sissoko, S Koita, B Togola, M Doura, S Koumare, A Togo","doi":"10.4314/mml.v40i4.5","DOIUrl":"10.4314/mml.v40i4.5","url":null,"abstract":"Introduction: Darier-FERRAND dermatofibrosarcoma is a slow-growing fibrous skin tumor with a very high risk of local recurrence but low metastatic potential.Objective: To determine the epidemiological, clinical, and therapeutic characteristics and analyze the treatment outcomes.Methodology: This was a retrospective, cross-sectional study from January 2018 to December 2023, including patients operated on for histologically confirmed Darier-FERRAND dermatofibrosarcoma (DFS).Results: Eight patients with DFS were included. The mean age was 49 years. The sex ratio was 7M/1F. Four were experiencing their first episode, three had undergone surgery once for the same tumor, and one patient was experiencing a second recurrence. The masses were located on the thigh in five cases, two on the trunk, and one on the left arm. The mean tumor size was 12.8 cm. The mean tumor duration was 18.1 months. The treatment decision was based on the presumptive diagnosis. Management was surgical in all patients. The surgical procedure performed in all patients was tumor excision in a healthy area with a 4 cm resection margin.Conclusion: Dermatofibrosarcoma of Darier-Ferrand type is a rare skin tumor. Its progression is very slow, with a very high risk of local recurrence if surgical excision is incomplete, hence the importance of wide surgical excision.","PeriodicalId":74061,"journal":{"name":"Le Mali medical","volume":"40 4","pages":"25-29"},"PeriodicalIF":0.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0