Journal of mother and child最新文献

{"title":"Breastfeeding Education Across the Perinatal Period: A Descriptive Exploratory Pre-Implementation Study.","authors":"Jennifer Abbass-Dick, Adrianna Trifunovski, Aisha Hussain, Manon Lemonde, Catherine Shaw, Keri Durocher","doi":"10.34763/jmotherandchild.20263001.d-26-00019","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00019","url":null,"abstract":"<p><strong>Background: </strong>Breastfeeding is the optimal infant feeding method; however, cessation rates remain high across many developed nations. Support for mothers can be improved through breastfeeding education that spans the entire perinatal period. Due to the number of healthcare providers involved, delivery of breastfeeding education must be consistent and tailored to individual needs. Digital innovations are a potential solution to enhance accessibility and consistency in breastfeeding education delivery. How to best implement these solutions in clinical settings is not yet known.</p><p><strong>Materials and methods: </strong>We used a non-experimental, exploratory descriptive survey to collect mothers' and providers' experiences of breastfeeding education, and their perceptions of how an eHealth resource can be adapted and implemented to standardise breastfeeding education.</p><p><strong>Results: </strong>The surveys were completed by 93 providers and 78 mothers. Mothers reported receiving education from diverse providers across the perinatal period, with varying information at different time points. Information was received on many topics that changed at various times. Oral communication was ranked as the most frequent education method. Both groups reported that online videos and websites would be the most effective digital solutions to support breastfeeding education.</p><p><strong>Conclusion: </strong>Providers play a crucial role in supporting mothers through education delivery that spans the entire perinatal period. By integrating the findings, accessibility and consistency of breastfeeding education could be enhanced by implementing the eHealth resource across organisations in a health region.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"167-179"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Sleep Disturbances as an Upstream Modulator of the Immunological Biomarker Profile in Early-Onset Preeclampsia.","authors":"Roheen Raza","doi":"10.34763/jmotherandchild.20263001.d-26-00016","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00016","url":null,"abstract":"","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"187-188"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The New Landscape of Cystic Fibrosis in the Era of Highly Effective Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy.","authors":"Anna Wołkowicz, Katarzyna Walicka-Serzysko, Justyna Milczewska, Dorota Sands","doi":"10.34763/jmotherandchild.20263001.d-26-00011","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00011","url":null,"abstract":"<p><strong>Background: </strong>For many years, the management of cystic fibrosis has had a personalised character. We have now entered an era of therapy based on a patient's specific genotype. Clinical trials have confirmed the efficacy and safety of cystic fibrosis transmembrane conductance regulator modulator therapies, including ivacaftor as monotherapy and triple-drug combinations, such as elexacaftor/tezacaftor/ivacaftor and vanzacaftor/tezacaftor/deutivacaftor. These therapies result in substantial and sustained improvements in lung function, a reduction in the frequency of bronchopulmonary exacerbations, enhanced nutritional status, and an improved quality of life. These clinical outcomes have been correlated with a marked reduction of sweat chloride values.</p><p><strong>Material and methods: </strong>Early initiation of therapy is crucial to halt disease progression or even reverse disease-related complications, which have even been observed in children aged six to twelve years. Initiating treatment in even younger children before the onset of clinical symptoms offers the possibility of a much later disease manifestation or even absence of symptoms. Nevertheless, careful evaluation of these therapies' long-term effects on the respiratory system and other organs remains necessary.</p><p><strong>Results: </strong>According to current knowledge, patients continue to require regular follow-up by a multidisciplinary care team and ongoing adjustment of both modulator and symptomatic therapies to meet individual needs.</p><p><strong>Conclusion: </strong>As patient life expectancy continues to increase, comorbidities such as arterial hypertension, hypercholesterolaemia, cardiovascular disease, and malignancies will assume greater clinical importance. Selecting optimal therapeutic strategies remains a significant clinical challenge due to the numerous potential interactions between modulators and other medications.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"180-186"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohaematological Testing, Monitoring, and Treatment of Haemolytic Disease of the Newborn: Where are we in this Field after 25 Years?","authors":"Marjana Jerković Raguž, Sanja Klarić, Mirela Mabić","doi":"10.34763/jmotherandchild.20263001.d-26-00007","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00007","url":null,"abstract":"<p><strong>Context: </strong>Prevention of pregnancy-related alloimmunisation and the management of haemolytic disease of the foetus and newborn (HDFN) has significantly improved over the past decades.</p><p><strong>Aim: </strong>Considering the improved HDFN care in recent years, the goal of this 25-year analysis is to determine the epidemiological aspects of alloimmunisation during pregnancy and the presentation, diagnosis, and treatment of different types of haemolytic disease of newborns (HDN).</p><p><strong>Materials and methods: </strong>The retrospective study encompasses all pregnant women whose immunohaematological screening detected antibodies against any of the antigens in ABO, Rhesus, Kell, Duffy, Kidd, and/or other blood group systems or had newborns who developed HDN.</p><p><strong>Results: </strong>Over the 25-year study period, 830/38,898 (2.1%) of immunohaematologically tested pregnant women developed alloimmunisation, while 556 (1.42%) of their newborns developed HDN. The most common form of HDN in our study was ABO HDN at 73.2% (407/556). RhD HDN was treated in 12.9% (72/556) of the newborns. Exchange transfusions (ET) were administered to 5.76% (32/556) of newborns with HDN. ET was performed on 24 (75%) with ABO HDN, and 8 (25%) with RhD HDN. The conclusion of this 25-year study is that alloimmunisation is still present, as are its consequences for the newborn. Despite better screening of pregnant women, diagnosis, and treatment of the consequences of alloimmunisation, we must know that there is no universal cure for HDN; therefore, continuous research and new guidelines in this field are needed.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"161-166"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal Glucocorticoid Exposure and Autism Spectrum Disorder: Current Evidence, Mechanisms, and Clinical Implications.","authors":"Saim Mahmood Khan, Jawairya Muhammad Hussain, Yousif Daud Channa, Syed Zawiar Muhammad, Afnan Shaikh, Uzair Virk, Abdullah Aftab Khan, Muhammad Ali Shahzad, Surraiya Riaz Mahmood Khan","doi":"10.34763/jmotherandchild.20263001.d-26-00003","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00003","url":null,"abstract":"<p><p>Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterised by social difficulties and repetitive behaviours. Genetic and environmental factors play a key role in its aetiology. Antenatal glucocorticoids, widely used to improve outcomes in preterm infants, have raised questions about potential long-term neurodevelopmental effects. This review aims to summarise the current literature on the association between prenatal glucocorticoid exposure and neurodevelopmental outcomes, including ASD, explore proposed biological mechanisms, and discuss clinical and public health implications. A comprehensive literature search was conducted in PubMed, Web of Science and Google Scholar using relevant keywords, focusing on observational studies, meta-analyses, and clinical studies that addressed neurodevelopmental consequences of prenatal glucocorticoid exposure, with priority given to studies evaluating ASD risk. Glucocorticoids reduce neonatal respiratory complications in preterm infants. Long-term neurodevelopmental outcomes, including ASD, are uncertain: some observational studies suggest increased risk, especially in late-preterm or term infants, while randomised trials show minimal adverse effects. Potential mechanisms include epigenetic changes, HPA axis disruption, and altered hippocampal development. Glucocorticoids are essential for improving the survival of preterm infants. Current evidence does not establish a causal link with ASD, but potential long-term neurodevelopmental effects warrant cautious use, careful patient selection, and continued long-term follow-up. Further well-controlled studies using standardised neurodevelopmental assessments are needed.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"129-144"},"PeriodicalIF":0.0,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13380255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148498444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doppler Evaluation of Foetal Pulmonary Artery in Intrahepatic Cholestasis of Pregnancy: A Prospective Study.","authors":"Sana Fatima, Nidhi Gupta, Abhinav Jain, Aruna Nigam, Sumedha Sharma","doi":"10.34763/jmotherandchild.20263001.d-26-00035","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00035","url":null,"abstract":"<p><strong>Background: </strong>Intrahepatic cholestasis of pregnancy (ICP) is the most prevalent liver disease specific to pregnancy, with higher incidence of adverse pregnancy outcomes. Keeping this in mind, this study has been framed to compare the changes in foetal pulmonary artery Doppler in pregnancies complicated with ICP with normal pregnancies.</p><p><strong>Materials and methods: </strong>This prospective study included total of 100 patients as per the inclusion and exclusion criteria. These patients were divided into two groups: the case group (ICP pregnancies) and control group (normal pregnancies). The Doppler parameters were analysed in terms of acceleration time/ejection time (AT/ET) ratio and the maternal and foetal outcome were evaluated.</p><p><strong>Results: </strong>Significant differences were found in Doppler parameters between the groups, with longer acceleration times (AT), shorter ejection times (ET), and higher PATET ratios in the ICP cases, which signify altered right ventricular outflow parameters, suggesting compromised pulmonary hemodynamics in newborns of ICP-affected pregnancies. These parameters were significantly influenced by the severity of ICP. The AT and ET, which are measures of cardiac function, show weak correlations with the liver function markers (all below 0.23), suggesting minimal direct relationships between these cardiac parameters and liver dysfunction in ICP patients.</p><p><strong>Conclusion: </strong>The altered Doppler parameters reflect changes in foetal pulmonary vascular resistance and could be indicative of lung immaturity or altered hemodynamics secondary to the toxic effects of elevated maternal bile acid levels.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"145-452"},"PeriodicalIF":0.0,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13380253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148498469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Fat Mass Obesity</i> Gene Predisposing in Preeclampsia in the Madura Population: A Case-Control Study.","authors":"Eny Susanti, Zakkiyatus Zainiyah, Novita Wulandari, Mochamad Amin, Iswahyudi","doi":"10.34763/jmotherandchild.20263001.d-26-00010","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00010","url":null,"abstract":"<p><strong>Background: </strong>Preeclampsia (PE) is a common complication of pregnancy characterised by hypertension, severe headaches, and protein in the urine, usually developing after 20 weeks of pregnancy. High body mass index before pregnancy is a risk factor for PE. One gene associated with obesity is the Fat Mass Obesity (FTO) gene. This study aimed to analyse the FTO gene predisposing to PE in the Madura population.</p><p><strong>Material and methods: </strong>The research design is a case-control design. A total of 110 pregnant women participated: 55 with severe PE and 55 healthy pregnant women. The inclusion criteria for the case group were patients with a history of PE who visited Syamrabu Bangkalan Regional Hospital and the independent midwifery practice, and who were of Madurese ethnicity. Blood samples were collected for FTO gene analysis; a questionnaire was used to obtain demographic data from pregnant women; and the FTO gene was analysed by tetra-primer amplification refractory mutation system polymerase chain reaction method, followed by sequencing and statistical analysis using Statistical Package for the Social Sciences (SPSS).</p><p><strong>Results: </strong>In normotensive pregnant women, the AA homozygous genotype was less common than in the PE group (1.8% vs 12.7%). The results were statistically significant (p = 0.018) between normotensive and preeclamptic pregnant women.</p><p><strong>Conclusion: </strong>The FTO gene may be a risk factor for PE and is associated with the AA homozygous genotype; further research with large sample sizes across diverse ethnicities is needed.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"153-160"},"PeriodicalIF":0.0,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13380254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148498393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"King-Denborough Syndrome-Dysmorphic Features Suggesting Risk of Malignant Hyperthermia.","authors":"Piotr Nowakowski, Karolina Czeczko, Anna Potulska-Chromik, Justyna Żelewska, Aleksandra Jastrzębska, Anna Wójcicka, Paweł Gaj, Anna Kostera-Pruszczyk","doi":"10.34763/jmotherandchild.20263001.d-26-00012","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00012","url":null,"abstract":"<p><strong>Background: </strong>King-Denborough syndrome is a rare disorder within the spectrum of RYR1-related myopathies. It is a congenital myopathy, with characteristic dysmorphic features, and susceptibility to malignant hyperthermia. Early recognition is clinically important because the diagnosis may affect anesthetic management and perioperative safety.</p><p><strong>Case presentation: </strong>We report a 4.5-year-old boy with delayed motor development, generalized hypotonia, characteristic dysmorphic features, and mildly elevated serum creatine kinase levels. The MRI showed features of asymmetrical atrophy and fatty degeneration in the proximal muscles of the lower limbs.</p><p><strong>Results: </strong>Molecular testing identified a heterozygous RYR1 variant. In the context of the clinical phenotype and muscle imaging findings, the presentation was considered suggestive of King-Denborough syndrome within the spectrum of RYR1-related disorders.</p><p><strong>Conclusion: </strong>This case highlights the importance of another RYR1-related myopathy in children presenting with myopathic features, dysmorphism, and muscle MRI abnormalities. Recognition of this phenotype is particularly important because of the potential risk of malignant hyperthermia and the need for appropriate anesthetic precautions.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"116-122"},"PeriodicalIF":0.0,"publicationDate":"2026-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Renal Changes in Bardet-Biedl Syndrome with Particular Emphasis on Kidney Size, Function, and Blood Pressure Control.","authors":"Zofia Moskal, Agnieszka Szmigielska","doi":"10.34763/jmotherandchild.20263001.d-26-00009","DOIUrl":"10.34763/jmotherandchild.20263001.d-26-00009","url":null,"abstract":"<p><strong>Introduction: </strong>Bardet-Biedl syndrome (BBS) is a genetically heterogeneous ciliopathy characterized by obesity, retinal dystrophy, cognitive impairment, hypogonadism, and congenital renal anomalies, which represent a leading cause of morbidity and mortality in affected patients.</p><p><strong>Material and methods: </strong>We followed four patients with BBS (three boys, one girl) from birth to ten years of age. In all children, we assessed physical development, laboratory tests, including assessment of renal function, renal ultrasound examination, and blood pressure control.</p><p><strong>Results: </strong>Patients (three males) with Bardet-Biedl syndrome, demonstrated prenatal and postnatal evidence of structural and functional renal abnormalities, including kidney injury and bilateral renal dysplasia. Neonatal serum creatinine ranged from 0.70 to 1.66 mg/dL, with persistently abnormal renal morphology on follow-up imaging and variable but overall stable renal function (latest creatinine 0.68-1.03 mg/dL). Arterial hypertension occurred in one male and one female patient and was effectively controlled with angiotensin-converting enzyme inhibitor therapy. All patients exhibited multisystem involvement characteristic of ciliopathy, including polydactyly, obesity, ophthalmologic abnormalities, neurodevelopmental impairment, and hypogonadism in three of four individuals.</p><p><strong>Conclusions: </strong>The broad spectrum of renal manifestations in BBS underscoring the importance of early diagnosis and individualized nephrological monitoring.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"123-128"},"PeriodicalIF":0.0,"publicationDate":"2026-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Performance of Machine Learning Models Using Food Intake Frequency Versus Vegetable Intake Data to Predict Problematic Mealtime Behaviour in Japanese Preschool Children.","authors":"Naoki Sakane, Yaeko Kawaguchi, Junichiro Somei, Akiko Suganuma, Masayuki Domichi","doi":"10.34763/jmotherandchild.20263001.d-25-00036","DOIUrl":"10.34763/jmotherandchild.20263001.d-25-00036","url":null,"abstract":"<p><strong>Background: </strong>Selective eating often leads to nutritional imbalance and mealtime stress, making early identification essential.</p><p><strong>Objective: </strong>This study aimed to compare the predictive performance of machine learning (ML) models using two types of input data-namely, vegetable intake and food frequency questionnaire (FFQ) responses-to identify children with selective eating behaviour (cutoff score ≥1.59).</p><p><strong>Material and methods: </strong>We analysed a cross-sectional dataset of 283 children aged 3-6 years using up to 8 predictors selected from 15 food-frequency items or 15 designated vegetables, along with age and sex. Selective eating behaviour was defined as a selective eating score of ≥ 1.59. Eleven ML algorithms were trained and evaluated, resulting in 11,253 feature-model combinations. Model performance was assessed using 5-fold cross-validation based on accuracy, precision, recall, F1 score, and ROC-AUC. Permutation importance analysis was conducted to identify key predictive features.</p><p><strong>Results: </strong>Among the 11 ML algorithms tested, vegetable intake-based L1 logistic regression showed the best performance (ROC-AUC = 0.717, accuracy = 0.647, precision = 0.722, recall = 0.659, F1 = 0.808). Permutation importance further identified tomato, green onion, and taro as key contributors in the vegetable intake-based L1 logistic regression model. In contrast, the FFQ-based Naïve Bayes model showed relatively good discrimination (ROC-AUC = 0.619) despite moderate recall.</p><p><strong>Conclusion: </strong>Vegetable intake-based ML models were more effective than those using FFQ data in identifying children with selective eating behaviour. Detailed dietary assessment aids early detection.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"30 1","pages":"106-115"},"PeriodicalIF":0.0,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13263313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148240811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}