Journal of mood and anxiety disorders最新文献

{"title":"Recurrent negative autobiographical memories and mental health","authors":"M. Alexandra Kredlow ,&nbsp;Hayley E. Fitzgerald ,&nbsp;Joseph K. Carpenter ,&nbsp;Nadine R. Taghian ,&nbsp;Michael W. Otto ,&nbsp;Stefan G. Hofmann ,&nbsp;Elizabeth A. Phelps","doi":"10.1016/j.xjmad.2024.100074","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100074","url":null,"abstract":"<div><h3>Background</h3><p>Recurrent symptom-relevant negative autobiographical memories are common in patients with emotional disorders such as anxiety and depression, even among those without a trauma-related diagnosis. Recurrent negative autobiographical memories may also contribute to distress in non-clinical populations.</p></div><div><h3>Methods</h3><p>To examine the prevalence of recurrent negative autobiographical memories and associated psychological features, we recruited a student sample (<em>n</em> = 101) and a treatment-seeking sample of patients with emotional disorders (<em>n</em> = 123). We hypothesized that recurrent negative autobiographical memories would be associated with higher levels of psychological symptoms and rumination. We also conducted exploratory analyses of participants’ most bothersome memory.</p></div><div><h3>Results</h3><p>In each sample, individuals who endorsed recurrent negative autobiographical memories had significantly higher depression, anxiety, and stress symptoms as well as greater rumination. In the treatment-seeking sample, where memories also had to be identified by patients as symptom-relevant, those who endorsed memories also had significantly higher clinician-rated symptom severity for their primary diagnosis. The majority of participants in each sample endorsed moderate or greater re-experiencing (sample 1: 79 %, sample 2: 66 %) and avoidance symptoms (sample 1: 78 %, sample 2: 58 %) related to their most bothersome memory.</p></div><div><h3>Conclusion</h3><p>Recurrent negative autobiographical memories relate to mental health symptoms in both clinical and non-clinical samples. Further research should explore whether targeting such memories reduces distress or improves wellbeing in these populations.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"8 ","pages":"Article 100074"},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000282/pdfft?md5=2da2d86b7f7561b27bf29c0f8af5923e&pid=1-s2.0-S2950004424000282-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141291412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the relationship between emotion regulation, sleep quality, and anxiety disorder diagnosis","authors":"Bryana L. Schantz ,&nbsp;Emma R. Toner ,&nbsp;Mackenzie L. Brown ,&nbsp;Nikki Kaiser ,&nbsp;Alan Chen ,&nbsp;Samrachana Adhikari ,&nbsp;Susanne S. Hoeppner ,&nbsp;Eric Bui ,&nbsp;Naomi M. Simon ,&nbsp;Kristin L. Szuhany","doi":"10.1016/j.xjmad.2024.100072","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100072","url":null,"abstract":"<div><p>Anxiety disorders are highly comorbid with sleep disturbance and have also been associated with deficits in emotion regulation, the ability to control and express emotions. However, the extent to which specific dimensions of sleep disturbance and emotion regulation are associated with anxiety diagnosis is not well-explored. This study examined dimensions of emotion regulation and sleep disturbance that may predict greater likelihood of anxiety diagnosis using novel machine learning techniques. Participants (Mean(SD) age= 28.6(11.3) years, 62.7% female) with primary anxiety disorders (n = 257), including generalized anxiety disorder (n = 122) and social anxiety disorder (n = 135), and healthy controls (n = 89) completed the Difficulties in Emotion Regulation Scale and Pittsburgh Sleep Quality Index. A conditional inference tree was fit to classify likelihood of current anxiety diagnosis based on predictors. The best model fit included 4 split nodes and 5 terminal nodes. Worse scores on two emotion regulation subscales, strategies directed to manage negative emotions and nonacceptance of negative emotions, were the best predictors of current anxiety diagnosis (99.3% probability of diagnosis). For those with better emotion regulation, poor sleep quality and worse daytime functioning due to sleep were important predictors of anxiety diagnosis. Good emotion regulation and non-disturbed sleep predicted high likelihood of being a non-psychiatric control (88.2%). Limitations include cross-sectional design precluding designating directionality of effects of sleep and emotion regulation on anxiety onset; limited sample size; and self-reported sleep. Facets of emotion regulation and sleep disturbance may be important early targets for brief intervention for anxiety disorders.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"8 ","pages":"Article 100072"},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000269/pdfft?md5=68381e0495e02dde6359991ed2fca936&pid=1-s2.0-S2950004424000269-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multi-method assessment of emotional processes predicting longitudinal anxiety symptom trajectories in an adolescent clinical sample","authors":"Doga Cetinkaya ,&nbsp;Sydney A. DeCaro ,&nbsp;Margarid R. Turnamian ,&nbsp;Jennifer A. Poon ,&nbsp;Evan M. Kleiman ,&nbsp;Richard T. Liu","doi":"10.1016/j.xjmad.2024.100071","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100071","url":null,"abstract":"<div><h3>Objective</h3><p>Emotion recognition, reactivity, and regulation are important in the development and maintenance of anxiety disorders. Whether and how these processes differentiate between different trajectories in anxiety remain unclear. The current study examined emotional processes as prospective predictors of anxiety symptom trajectories in psychiatrically hospitalized youth.</p></div><div><h3>Method</h3><p>Participants were 180 adolescents (<em>M</em>_age = 14.89; <em>SD</em> = 1.35) from a psychiatric inpatient unit. At index hospitalization, participants completed a behavioral task assessing facial emotion recognition, and self-report measures of emotion dysregulation and reactivity. They completed a self-report measure on anxiety symptoms at baseline and 3, 6, 12, and 18 months post-discharge. Latent growth curve analysis was conducted to identify subgroups of individuals based upon their trajectory of anxiety symptoms across 18-months. ANOVAs were used to examine subgroup differences in emotional processing variables.</p></div><div><h3>Results</h3><p>Three distinct trajectories were identified, a stable moderate-to-high anxiety group, a group with moderate-to-high anxiety at baseline with symptom improvement over time, and a group characterized by relatively stable low-to-moderate anxiety throughout the study. The two initially moderate-to-high anxiety groups scored higher for emotion dysregulation and emotion reactivity at baseline compared to the low-to-moderate anxiety group. Emotion regulation difficulties relating to emotional non-acceptance were higher for the stable moderate-to-high anxiety group than for the moderate-to-high anxiety group that experience symptom improvement over time.</p></div><div><h3>Conclusions</h3><p>These findings may have clinical implications for discharge planning. Future studies should explore emotion regulation with a focus on non-acceptance of one’s emotional experiences as a potential target of intervention in individuals with elevated anxiety.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"7 ","pages":"Article 100071"},"PeriodicalIF":0.0,"publicationDate":"2024-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000257/pdfft?md5=d9e9e029584e14e32a78632201db6ad0&pid=1-s2.0-S2950004424000257-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140645954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between experiences of discrimination, anxiety, and mood symptoms in Black women: Investigating the mediating role of attentional control","authors":"Courtney C. Louis ,&nbsp;NiCole T. Buchanan ,&nbsp;Jason S. Moser","doi":"10.1016/j.xjmad.2024.100070","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100070","url":null,"abstract":"<div><p>A recent study found that attentional control is a key mechanism that accounts for the association between discriminatory experiences and health outcomes in Black women. We replicate and extend this finding by testing the mediating role of attentional control in the association between discrimination and symptoms of anxiety and depression symptoms. A total of 128 Black women completed an online survey that assessed experiences of discrimination, anxiety, depression and attentional control. Three models were conducted to examine associations between experiences of discrimination and three outcomes (worry, anxious arousal, and anhedonic depression), and whether attentional control mediated these effects. Our findings revealed that more frequent discrimination predicted less attentional control and heightened anxiety symptoms. In support of our hypotheses, we found that attentional control mediated the association between discrimination and anxious arousal and anhedonic depression. Attentional control did not mediate the association between experiences of discrimination and worry, however. Our findings dovetail with previous research suggesting that experiences of discrimination tax prefrontal regions associated with attentional control and could be a pathway that leads to somatic anxiety and depression. Our findings also amplify the need to assess experiences of discrimination in therapeutic assessment and intervention with Black women.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"7 ","pages":"Article 100070"},"PeriodicalIF":0.0,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000245/pdfft?md5=a49a327ac352df4f87be89943e064087&pid=1-s2.0-S2950004424000245-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140645951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal dynamics of positive and negative affect in adolescents: Associations with depressive disorders and risk","authors":"George Abitante ,&nbsp;David A. Cole ,&nbsp;Christian Bean ,&nbsp;Madison Politte-Corn ,&nbsp;Qimin Liu ,&nbsp;Anh Dao ,&nbsp;Lindsay Dickey ,&nbsp;Samantha Pegg ,&nbsp;Autumn Kujawa","doi":"10.1016/j.xjmad.2024.100069","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100069","url":null,"abstract":"<div><p>Alterations in dynamic affective processes are associated with dysregulated affect and depression. Although depression is often associated with heightened inertia (i.e., greater moment-to-moment correlation) and variability (i.e., larger departures from typical levels) of affect in adults, less is known about whether altered affect dynamics are present in youth at risk for depression. This study investigated the association of clinical depression and depression risk with the inertia and variability of positive and negative affect in a sample of youth at varying risk for depression. Our sample included 147 adolescents aged 14 to 17, categorized into three groups: never-depressed lower-risk, never-depressed higher-risk (based on maternal history of depression), and currently depressed adolescents. Adolescents completed ecological momentary assessments of positive and negative affect up to seven times per day for a week. Multilevel models and ANOVAs were used to examine associations of affective inertia and variability with adolescent depression and risk based on maternal history, controlling for average affect. Depressed adolescents showed more inert and diminished positive affect, and more variable and elevated negative affect compared to lower- and higher-risk youth, though associations attenuated after controlling for average affect. No differences were identified between never-depressed higher-risk and lower-risk youth. Additional longitudinal studies are needed to evaluate whether altered affect dynamics in daily life precede depression onset to understand their utility for developing preventive interventions.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"7 ","pages":"Article 100069"},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000233/pdfft?md5=647d368a471b6a45377d5a2d66f2f6c0&pid=1-s2.0-S2950004424000233-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140631645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal neural sensitivity to rewards as a candidate process of high depression risk in the FMR1 premutation: A pilot study","authors":"Roslyn Harold ,&nbsp;Bridgette Kelleher ,&nbsp;Keisha Novak ,&nbsp;Wei Siong Neo ,&nbsp;Teagan Stump ,&nbsp;Taylor Lee ,&nbsp;Tessa Garwood ,&nbsp;Elizabeth Berry-Kravis ,&nbsp;Dan Foti","doi":"10.1016/j.xjmad.2024.100068","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100068","url":null,"abstract":"<div><p>The etiological heterogeneity of depression poses a challenge for prevention and intervention efforts. One solution is to map unique etiological pathways for subgroups defined by a singular risk factor. A relevant population for this approach is women who carry the premutation of the <em>fragile X messenger ribonucleoprotein</em> 1 (<em>FMR</em>1) gene, who are at high risk for adult-onset depression. This study explores a candidate neurophysiological marker of depression risk: reduced reward sensitivity, indexed by the reward positivity (RewP). The RewP has been linked to depression risk in the general population, but is unexplored within <em>FMR</em>1 premutation carriers. 16 women with the <em>FMR</em>1 premutation and a matched control group completed a simple guessing task while the electroencephalogram was recorded. Among premutation carriers, RewP difference score (win versus loss) was reduced. These preliminary finding suggest that the <em>FMR</em>1 premutation may confer increased risk for depression in part through abnormal neural sensitivity to rewards.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"6 ","pages":"Article 100068"},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000221/pdfft?md5=27a3828560b7939a7261f4feff08f003&pid=1-s2.0-S2950004424000221-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140348331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interactions between anxiety and impulsive dimensions are differentially associated with experiential avoidance","authors":"Sonalee A. Joshi ,&nbsp;D. Angus Clark ,&nbsp;James L. Abelson ,&nbsp;Elizabeth R. Duval","doi":"10.1016/j.xjmad.2024.100067","DOIUrl":"10.1016/j.xjmad.2024.100067","url":null,"abstract":"<div><p>Anxiety and impulsivity often co-occur, but due to broad conceptualizations of impulsive behavior, it remains unclear whether anxiety could be positively associated with global impulsivity or specific facets of impulsivity. Negative urgency, or rash behavior that specifically occurs during negative emotional states, may provide common ground to examine the overlap between high anxiety and high impulsivity. Limited work has examined relationships between negative urgency and behavioral processes that are often associated with both anxiety and global impulsivity, such as experiential avoidance. In this study, we examined self-report data collected from a non-clinical sample of adult participants (n = 589) to test relationships between anxiety and experiential avoidance through both negative urgency and global impulsivity. Contrary to hypotheses, we found that negative urgency alone did not alter the relationship between anxiety and experiential avoidance. However, follow-up analyses including data-driven factors of impulsivity revealed that in combination, anxiety and both emotion-based impulsivity (i.e. negative and positive urgency) and hyperactivity were linked to greater experiential avoidance. By contrast, anxiety and non-planning were associated with lower experiential avoidance. These results provide targets for future studies to examine individual differences in profiles of co-occurring anxiety and impulsivity.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"6 ","pages":"Article 100067"},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S295000442400021X/pdfft?md5=15e7e0ab14cbfab3d3da642818d4e6b3&pid=1-s2.0-S295000442400021X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140403390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing generalized anxiety disorder screening in young adults perinatally affected by HIV: A psychometric analysis","authors":"Corey Morrison ,&nbsp;Claude A. Mellins ,&nbsp;Clayton Synder ,&nbsp;Eileen Shea ,&nbsp;Luke Kluisza ,&nbsp;Reuben Robbins ,&nbsp;Ohemaa Poku ,&nbsp;Prudence Fisher ,&nbsp;Elaine Abrams ,&nbsp;Andrew Wiznia ,&nbsp;Laura Mufson","doi":"10.1016/j.xjmad.2024.100066","DOIUrl":"10.1016/j.xjmad.2024.100066","url":null,"abstract":"<div><h3>Background</h3><p>Generalized Anxiety Disorder (GAD) is prevalent among people with HIV and is associated with adverse health outcomes. This study investigates the suitability of the Generalized Anxiety Disorder Scale-7 item (GAD-7) screening tool and its 2-item (GAD-2) version for use in young adults with perinatally-acquired HIV (YAPHIV) and young adults perinatally exposed to HIV but uninfected (YAPHEU).</p></div><div><h3>Methods</h3><p>Data come from the 7th follow-up interview (FU7) from a longitudinal study of youth with PHIV and PHEU, first recruited when 9–16 years. The GAD-7 was administered along with a diagnostic psychiatric interview (DISC-IV). Receiver Operating Characteristic analysis assessed accuracy, sensitivity, and specificity of the GAD7 and GAD-2. Subgroup analyses considered HIV status, ethnicity, and race.</p></div><div><h3>Results</h3><p>At FU7, participants (n = 204) were ages 20–29; 54% female; and the majority African-American and/or Latinx. 12% met diagnostic criteria for GAD. Recommended GAD-7 (&gt;10) and GAD-2 (&gt;3) cut-scores showed suboptimal sensitivity (0.52 and 0.48, respectively) and high specificity (0.91 and 0.90, respectively). Lowering cut-scores (GAD-7 &gt;6 and GAD-2 &gt;2) improved sensitivity (0.76 and 0.80) while sacrificing specificity (0.77 and 0.78). Stratified analyses by HIV status revealed similar accuracy in YAPHIV and YAPHEU. Race/ethnicity did not significantly affect cut-scores.</p></div><div><h3>Discussion</h3><p>Anxiety disorders are common in YAPHIV, and efficient screening is essential. While the GAD-7 and GAD-2 show promise, recommended cut-scores may not be optimal. Lowering cut-scores may enhance sensitivity without losing clinical utility. Further research is needed to refine cut-scores based on demographic characteristics and in global contexts, ensuring effective anxiety screening in this population.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"7 ","pages":"Article 100066"},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000208/pdfft?md5=b48ae3cfe7e849065df71095aa993c1a&pid=1-s2.0-S2950004424000208-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140404532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicide without warning: Results from the Army Study to Assess Risk and Resilience in Servicemembers (STARRS)","authors":"Catherine L. Dempsey ,&nbsp;Jingning Ao ,&nbsp;Matthew W. Georg ,&nbsp;Pablo A. Aliaga ,&nbsp;David A. Brent ,&nbsp;David M. Benedek ,&nbsp;Kelly L. Zuromski ,&nbsp;Matthew K. Nock ,&nbsp;Steven G. Heeringa ,&nbsp;Ronald C. Kessler ,&nbsp;Murray B. Stein ,&nbsp;Robert J. Ursano","doi":"10.1016/j.xjmad.2024.100064","DOIUrl":"10.1016/j.xjmad.2024.100064","url":null,"abstract":"<div><h3>Objectives</h3><p>The rate of suicide increased in members of the United States Army since 2011 after the Iraq and Afghanistan wars and continues to be a major concern. In order to reverse this disturbing trend, it is vital to understand the risk and protective factors for suicide death in servicemembers.</p></div><div><h3>Methods</h3><p>Data were obtained from a case-control psychological autopsy study, which compared U.S. Army suicide decedent cases (n = 135) to a probability sample of living controls (n = 255) who are also service members weighted to be representative of the Army. Interviews were conducted with next-of-kin (NOK) and supervisor (SUP) informants. Multivariable logistic regressions models were constructed using predictors significant after controlling for multiple comparisons.</p></div><div><h3>Results</h3><p>The most parsimonious multivariable model controlling for deployment status, as reported by SUP predicting suicide death consisted of four significant variables: a spouse or partner left him or her in the past month (OR = 28.5 [95% CI = 1.8, 442.7] χ² = 5.72, <em>p</em> = .0168); a smaller social network (OR = 4.2 [95% CI = 1.0, 17.3] χ² = 3.97, <em>p</em> = .0462), less likely to seek help from a mental health counselor (OR = 3.4 [95% CI = 1.2, 9.7] χ² = 5.35, <em>p</em> = .0207) and more likely to be described as incautious (OR = 3.8 [95% CI = 1.2, 11.7] χ² = 5.42, <em>p</em> = .0199). The AUC = .88 [95%CI = 0.82, 0.94] for this regression model suggests strong prediction.</p></div><div><h3>Conclusions</h3><p>Our findings suggest that recent relationship problems, especially in soldiers who are less likely to seek out support from others, may be warning signs for detection and prevention of imminent risk of suicide and according to supervisor informant surveys, had neither evidence of a mental health disorder, nor disclosed suicidal ideation or self-harm. Implications for suicide prevention are discussed.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"7 ","pages":"Article 100064"},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S295000442400018X/pdfft?md5=5d8332cbaf9f1926576b2e3d2357881d&pid=1-s2.0-S295000442400018X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smaller hippocampal volume is associated with anxiety symptoms in high-risk Black youth","authors":"Rebecca Lipschutz ,&nbsp;Abigail Powers ,&nbsp;Sean T. Minton ,&nbsp;Anais F. Stenson ,&nbsp;Timothy D. Ely ,&nbsp;Jennifer S. Stevens ,&nbsp;Tanja Jovanovic ,&nbsp;Sanne J.H. van Rooij","doi":"10.1016/j.xjmad.2024.100065","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100065","url":null,"abstract":"<div><p>Although there is an established link between smaller hippocampal volume and anxiety, the longitudinal relations between hippocampus structure and anxiety in diverse youth are not well understood. The present longitudinal study investigated hippocampal volumes related to anxiety symptoms in a sample of Black 8–14-year-old youth (N = 64), a population historically underrepresented in neuroimaging research. Smaller hippocampal volumes were associated with greater anxiety symptoms independent of age, sex, intracranial volume and trauma exposure. Exploratory longitudinal analyses showed smaller hippocampal volume as a predictor for anxiety symptoms (n = 37) and not a consequence of anxiety symptoms (n = 32), however results were inconclusive as this finding was no longer significant after correcting for baseline anxiety symptoms. Overall, this data increases our understanding of potential neurobiological mechanisms for anxiety in a high-risk sample of Black youth and suggests future directions into studying trajectories of developmental risk.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"7 ","pages":"Article 100065"},"PeriodicalIF":0.0,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000191/pdfft?md5=1f33074d0b5b457e8d37b1b1c8101dc1&pid=1-s2.0-S2950004424000191-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140141873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}