Lennard Geiss , Beate Beck , Mark Stemmler , Thomas Hillemacher , Katharina M. Hösl
{"title":"Heart rate variability during inpatient treatment of depression","authors":"Lennard Geiss , Beate Beck , Mark Stemmler , Thomas Hillemacher , Katharina M. Hösl","doi":"10.1016/j.xjmad.2024.100059","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100059","url":null,"abstract":"<div><h3>Background</h3><p>Major depressive disorder (MDD) is linked to reduced heart rate variability, an index of cardiovascular autonomic modulation (CAM). However, treatment effects on CAM are poorly known. Our objective was to assess if initiation of inpatient treatment has a beneficial effect on CAM in MDD patients.</p></div><div><h3>Methods</h3><p>In 30 MDD inpatients, we recorded RR-intervals (RRI), continuous blood pressure (BPsys, BPdia), skin conductance levels (SCL), respiration frequency (RESP) and current medication within 24 h (T1) and 3 weeks after hospital admission (T2) during resting state and metronomic breathing. The same parameters were recorded once at baseline in 30 controls without mental disorders. We computed indices of sympathetic modulation, parasympathetic modulation and parameters reflecting total CAM. Physiological parameters were compared using MANCOVAS. Symptoms of depression were assessed using Hamilton rating scale for depression (HAM-D) and Beck Depression Inventory (BDI), we used rmANOVAs to compare t1 and t2 questionnaire data.</p></div><div><h3>Results</h3><p>BDI and HAM-D scores were lower at T2 than T1 (both p < 0.01). RRI was lower in T1 patients than in controls (p = 0.021), while BPdia (p = 0.038) and RESP (p = 0.014) were higher in T1 patients than controls. MDD patients showed lower parameters of parasympathetic modulation and total CAM than controls during resting state (parasympathetic p = 0.003; total CAM p = 0.017) and metronomic breathing (parasympathetic p = 0.040; total CAM p = 0.007). Analysis unveiled lower parameters of parasympathetic modulation in T1 patients compared to T2 patients during baseline (p = 0.046). No differences between T1 and T2 patients during metronomic breathing were found.</p></div><div><h3>Conclusion</h3><p>MDD patients showed lower CAM than controls. Contrary to our assumption, we found a decline of parasympathetic modulation in MDD patients over the observation span despite symptomatic improvement. The decline is presumably due to the initiation of psychopharmacotherapy and changes in premedication.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"6 ","pages":"Article 100059"},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000130/pdfft?md5=87a73fd161efebc0e39ace845c9013c8&pid=1-s2.0-S2950004424000130-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139999619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danielle Moskow Diamond , David Rosenfield , Nikki Kaiser , Amanda W. Baker , Elizabeth A. Hoge , Sat Bir S. Khalsa , Stefan G. Hofmann , Naomi M. Simon
{"title":"Changes in mindfulness facets across yoga, CBT and stress education in individuals with generalized anxiety disorder","authors":"Danielle Moskow Diamond , David Rosenfield , Nikki Kaiser , Amanda W. Baker , Elizabeth A. Hoge , Sat Bir S. Khalsa , Stefan G. Hofmann , Naomi M. Simon","doi":"10.1016/j.xjmad.2024.100058","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100058","url":null,"abstract":"<div><p>Improving mindfulness is an important treatment target for generalized anxiety disorder (GAD). However, less is known about how different treatments impact specific aspects of mindfulness. In a clinical trial (Simon et al., 2021), 226 individuals with GAD were randomized to 12 weeks of Kundalini Yoga (KY), cognitive behavioral therapy (CBT) or stress education (SE). To examine whether specific facets of mindfulness, as measured by the Five Facet Mindfulness Questionnaire (FFMQ) change more than others across treatment and between treatments, we ran a multi-variate multilevel growth curve model (MMLM). Results indicated that while the Non-judge, Act with Awareness, and Non-react facets increased significantly during treatment, the Observe and Describe facets did not. Improvement in the Acting with Awareness facet during treatment was significantly greater for KY than CBT. These findings reveal the need to better understand how behavioral treatments can influence specific components of mindfulness for those with anxiety.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"6 ","pages":"Article 100058"},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000129/pdfft?md5=2f4896c334a1686806e2ca7faaac57fe&pid=1-s2.0-S2950004424000129-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140041461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eva Asselmann , Frank Rückert , Hanna Kische , Monique Zenker , Lars Pieper , Katja Beesdo-Baum
{"title":"Cognitive, behavioral, and affective mechanisms underlying the efficacy of Applied Relaxation in reducing psychopathological symptoms: A randomized controlled trial","authors":"Eva Asselmann , Frank Rückert , Hanna Kische , Monique Zenker , Lars Pieper , Katja Beesdo-Baum","doi":"10.1016/j.xjmad.2024.100055","DOIUrl":"10.1016/j.xjmad.2024.100055","url":null,"abstract":"<div><h3>Background</h3><p>This study examined the cognitive, behavioral, and affective mechanisms underlying the efficacy of Applied Relaxation (AR) in reducing psychopathological symptoms. AR is a cognitive-behavioral technique that allows for rapid relaxation at the first sign of stress or tension in daily life.</p></div><div><h3>Methods</h3><p>A randomized controlled trial was conducted in 277 adults (18–55 years) with elevated symptoms of depression, anxiety, or stress but without a 12-month DSM-5 mental disorder at study entry. Participants were randomized to an intervention group receiving AR training (10 weeks, N = 139) and an assessment-only control group (N = 138). Mental health outcomes (depressive, anxiety, and stress symptoms) and potential cognitive (self-efficacy, perceived control), behavioral (coping behaviors) and affective (positive and negative affect) mediators of the intervention efficacy were assessed at baseline and post-assessment in both groups.</p></div><div><h3>Results</h3><p>Structural equation models indicated that baseline to post reductions in psychopathological symptoms due to AR partially passed through less avoidance-oriented and less other dysfunctional coping (proportion of total effect mediated; ratio of indirect to total effect: resignation: 55.0%, rumination: 27.9%, escape: 27.4%, aggression: 21.3%), less negative affect (46.3%), more positive affect (41.8%), lower external control beliefs (14.5%), and higher self-efficacy (13.3%).</p></div><div><h3>Conclusions</h3><p>Our results suggest that improvements in cognitive, behavioral, and affective mediator variables partially explain the intervention efficacy of AR in improving mental health.</p></div><div><h3>Trial registration and data statement</h3><p>The study protocol has been pre-registered on ClinicalTrials.gov (NCT03311529). The study protocol, minimum dataset, and analysis codes are available at OpARA - Open Access Repository and Archive. Supplementary materials (e.g., the course manual and additional training materials) are available on request from the last author ([email protected]).</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"6 ","pages":"Article 100055"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000099/pdfft?md5=cb07cef1960460dede381e82364672ab&pid=1-s2.0-S2950004424000099-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139965644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaylee E. Null , Jessica M. Duda , Diego A. Pizzagalli
{"title":"Social support mediates the effects of childhood unpredictability on anhedonia: A retrospective investigation in an online adult community sample","authors":"Kaylee E. Null , Jessica M. Duda , Diego A. Pizzagalli","doi":"10.1016/j.xjmad.2024.100057","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100057","url":null,"abstract":"<div><p>Increasingly, research is highlighting the implications of exposure to unpredictable environments during childhood (i.e., “childhood unpredictability”) on outcomes in adulthood. Converging evidence from preclinical and clinical studies has implicated childhood unpredictability in disrupted reward processing and anhedonia. From the stress generation literature, altered social support has emerged as a possible mechanism by which this effect may occur. In the current study, our goal was to understand whether the pathway from childhood unpredictability to anhedonia occurs through reduced perceptions of social support. Toward this end, we recruited an online community sample of adults in the US (<em>N</em> = 242) to complete surveys assessing childhood unpredictability, depressive symptoms, anhedonia, and social support, as well as a novel online version of the Probabilistic Reward Task. We found that childhood unpredictability was associated with increased depressive symptoms and anhedonia (but not objective measure of anhedonia), and reduced perceptions of social support in adulthood. Mediation analyses revealed a significant indirect effect of perceived social support on the association between childhood unpredictability and anhedonia, controlling for age, sex, and non-anhedonic depressive symptoms. Unexpectedly, measures of reward responsiveness from the behavioral task were not related to childhood unpredictability. The current findings replicate previous reports linking childhood unpredictability and self-reported anhedonia, and extend them to incorporate the potential mediating pathway of reduced social support. Implications for treatment for anhedonia are discussed.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"6 ","pages":"Article 100057"},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000117/pdfft?md5=13a70927f42aadd0e8274e9946cf7a7f&pid=1-s2.0-S2950004424000117-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139935899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jill C. Fodstad , Lauren B. Jones , Micah Iticovici , Rachel M. Russell , Molly Bullington , Emily Meudt
{"title":"The state of anxiety treatments for adolescents and adults down syndrome: Results from a scoping rapid review","authors":"Jill C. Fodstad , Lauren B. Jones , Micah Iticovici , Rachel M. Russell , Molly Bullington , Emily Meudt","doi":"10.1016/j.xjmad.2024.100056","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100056","url":null,"abstract":"<div><p>Adolescents and adults with Down syndrome are noted to display symptoms consistent with various anxiety disorders. While evidenced-based practices, including psychotherapies and psychopharmacology, exist and effectively treat anxiety in neurotypical populations, less is known about anxiety treatments for persons with Down syndrome. A scoping rapid review was conducted in April 2023 to determine what treatments are being used to target anxiety in adolescents and adults with Down syndrome, the quality of those treatments, and their alignment with current evidence-based practices. A total of eleven articles, primarily single case or case series, published between 1981 and 2022 were identified targeting adolescents and adults with Down syndrome diagnosed with specific phobias, selective mutism, generalized anxiety disorder, agoraphobia with panic, and non-specific anxiety symptoms. Interventions used most often aligned with evidence-based anxiety treatment guidelines and included psychotherapy, complementary and alternative medicine, and psychopharmacology. While most studies reported positive treatment responses showing reductions in anxiety symptoms post-treatment, the quality and generalizability of the studies was primarily poor. More rigorous research evaluating the effects of treatment for anxiety symptoms in the DS population are needed to develop guidelines to address anxiety disorders in this vulnerable population.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"6 ","pages":"Article 100056"},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000105/pdfft?md5=8273d53d779be8156ecce4dbea1b4080&pid=1-s2.0-S2950004424000105-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139935900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Crystal C. Wang , Mariel Emrich , Hal Rives , Annell Ovalles , Drew Wright , Katarzyna Wyka , JoAnn Difede
{"title":"Music interventions for posttraumatic stress disorder: A systematic review","authors":"Crystal C. Wang , Mariel Emrich , Hal Rives , Annell Ovalles , Drew Wright , Katarzyna Wyka , JoAnn Difede","doi":"10.1016/j.xjmad.2024.100053","DOIUrl":"10.1016/j.xjmad.2024.100053","url":null,"abstract":"<div><p>There is growing literature supporting the efficacy of music interventions for a range of conditions, including anxiety, stress, and pain. Alongside this, research on neurobiological processes involved in the experience of music has illuminated potential mechanisms for music’s role in mental health treatments. Music has the potential to act on the circuitry of the brain involved in the autonomic dysregulation associated with posttraumatic stress disorder (PTSD). We conducted a systematic review to identify studies examining the effects of music interventions on PTSD symptoms in adults. Five databases were searched which resulted in 2454 articles, with 1478 screened on title and abstract, and 288 screened at full text. 14 studies met inclusion criteria for the review. Study samples ranged from 6 to 330 participants who endorsed PTSD symptoms consequent to various traumas. Most studies were feasibility studies (<em>n</em> = 9), which employed the traditional music therapy format of therapist-led interventions (<em>n</em> = 11). While effective, these require active participation and are resource-intensive. Studies that used passive listening also showed a benefit of the music intervention (<em>n</em> = 5). All but one study reported a decrease in PTSD symptoms (<em>n</em> = 13). Although these findings should be interpreted considering the limitations of the studies (including small sample sizes and lack of rigorous control groups), these results demonstrate the promise of music interventions. Thus, as interest in music medicine grows rapidly amidst the increasing public health burden of PTSD, additional studies of the effect of music on PTSD symptoms are warranted. Studies that employ brief, self-directed, passive-listening music interventions that are delivered in inexpensive, scalable, and flexible formats may be especially promising.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"6 ","pages":"Article 100053"},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000075/pdfft?md5=48791924f6aef4a1a8f2f8449da22bba&pid=1-s2.0-S2950004424000075-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139829323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suzanne H. So , Anson Kai Chun Chau , Brandon A. Gaudiano , Lyn Ellett , Tania M. Lincoln , Eric M.J. Morris , Jessica L. Kingston
{"title":"The relationship between risk perception, anxiety and paranoia – A predictive model in a community sample","authors":"Suzanne H. So , Anson Kai Chun Chau , Brandon A. Gaudiano , Lyn Ellett , Tania M. Lincoln , Eric M.J. Morris , Jessica L. Kingston","doi":"10.1016/j.xjmad.2024.100052","DOIUrl":"10.1016/j.xjmad.2024.100052","url":null,"abstract":"<div><h3>Background</h3><p>Biases in risk perception (e.g. excessive attribution of likelihood of negative events happening to oneself, or perceived harm of neutral events) have been suggested as risk factors for psychopathologies such as generalised anxiety and persecutory ideation, although this line of research is limited by small samples and a lack of a suitable risk perception scale.</p></div><div><h3>Methods</h3><p>Using the Risk Perception Questionnaire, four risk perception dimensions (likelihood, harm, controllability, and intentionality) of negative and neutral events were tested in association with anxiety and paranoia. In view of common co-occurrence between the two symptom variables, their associations with risk perception were tested by using partial correlations (at baseline) and comparisons of cross-lagged path models (over 3 months).</p></div><div><h3>Results</h3><p>A representative community-based sample of 445 adults were included. At baseline, after controlling for correlations between levels of anxiety and paranoia, anxiety was uniquely correlated with three risk perception dimensions for negative events (likelihood, harm, and intentionality), whereas paranoia was uniquely correlated with all risk perception dimensions for both negative and neutral events. The best-fitted cross-lagged path model revealed that, after controlling for auto-regressions within variables, baseline level of anxiety predicted perceived harm of negative events at 3 months, whereas baseline levels of perceived intentionality of neutral events and likelihood of negative events predicted level of paranoia at 3 months.</p></div><div><h3>Conclusions</h3><p>While risk perception of negative events is shared between anxiety and paranoia, risk perception of neutral events is uniquely characteristic of paranoia. Implications on maintenance of sub-clinical symptoms are discussed.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"5 ","pages":"Article 100052"},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000063/pdfft?md5=0077f63d286e2309cc26f2714a960730&pid=1-s2.0-S2950004424000063-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139635711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lindsay Dickey, Anh Dao, Samantha Pegg, Autumn Kujawa
{"title":"Neural markers of emotion regulation difficulties in adolescent depression and risk for depression","authors":"Lindsay Dickey, Anh Dao, Samantha Pegg, Autumn Kujawa","doi":"10.1016/j.xjmad.2024.100051","DOIUrl":"10.1016/j.xjmad.2024.100051","url":null,"abstract":"<div><p>Depressed individuals tend to use maladaptive emotion regulation strategies more frequently than non-depressed individuals while using adaptive strategies (e.g., reappraisal) less frequently. Objective neural markers of emotion regulation ability could aid in identifying youth at greatest risk for depression and functional impairment more broadly. We used electroencephalography to examine emotion regulation in adolescents (aged 14–17; <em>N</em> = 201) with current depression (<em>n</em> = 94) and without any history of depression (<em>n</em> = 107) at high (<em>n</em> = 54) and low (<em>n</em> = 53) risk for depression based on a maternal history of depression. Results revealed group differences in event-related potential markers of emotion regulation using multiple scoring approaches. Never-depressed adolescents had significant reductions in mean-activity and principal component analysis-identified late positive potential responses to dysphoric stimuli under reappraisal instructions compared to passive viewing. There was no significant difference in neural responses between conditions among depressed adolescents. The magnitude of the reappraisal effects appeared slightly stronger for low-risk adolescents relative to high-risk. Exploratory analyses further demonstrated that the association between neural markers of emotion regulation and overall functioning was moderated by age, such that impaired emotion regulation abilities predicted poorer functioning among older adolescents. Findings support the sensitivity of the late positive potential to emotion regulation impairments in depression and psychopathology more broadly.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"5 ","pages":"Article 100051"},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000051/pdfft?md5=bc3c3e55c79b2ef6790c95827a2eb9e8&pid=1-s2.0-S2950004424000051-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139631800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anhedonia influences threat avoidance and relief: A conceptual replication","authors":"Lu Leng , Tom Beckers , Bram Vervliet","doi":"10.1016/j.xjmad.2024.100050","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100050","url":null,"abstract":"<div><p>Active threat avoidance is an adaptive coping strategy but can evolve into maladaptive behavior patterns when it is disproportionate to an actual threat. While excessive and persistent avoidance, as often seen in anxiety-related disorders, have been investigated extensively, it is presently unclear under what circumstances insufficient avoidance might occur in the presence of a genuine threat. We hypothesized that anhedonia, the reduced ability to experience pleasure, might undermine the relief experience after successful threat avoidance and thus reduce future active avoidance responses. Using an established avoidance learning paradigm, we examined the relationship between anhedonia, relief, and active avoidance responses. Forty participants learned that two threat cues signaled electrical stimulation and they could click a button during cue presentations to prevent electrical stimulation from occurring. While clicking the button worked for one threat cue, it did not work for the other one. After several repetitions, button effectiveness was reversed. Another safety cue that never signaled electrical stimulation was presented intermixed with the two threat cues. Every time there was an omission of electrical stimulation, self-reported relief was measured. We found that participants who scored higher on anhedonia experienced weaker relief during all outcome omissions. Behaviorally, at the early stage of each phase, participants who scored higher on anhedonia executed fewer avoidance actions, specifically for the threat cue that signaled avoidable electrical stimulation. Relief induced by threat omission is a pleasant experience, which trait anhedonia seems to impair. This attenuation of relief might reduce the reinforcement of future adaptive avoidance behaviors.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"5 ","pages":"Article 100050"},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S295000442400004X/pdfft?md5=7d8ac5d3359251d0d97bcecbb2753d53&pid=1-s2.0-S295000442400004X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139549803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abigail Powers , Emma C. Lathan , Elizabeth McAfee , Yara Mekawi , H. Drew Dixon , Estefania Lopez , Shifa Ali , Rebecca Hinrichs , Bekh Bradley , Sierra Carter , Nadine J. Kaslow
{"title":"Feasibility and acceptability of a virtual mindfulness intervention for Black adults with PTSD and depression: Randomized controlled trial","authors":"Abigail Powers , Emma C. Lathan , Elizabeth McAfee , Yara Mekawi , H. Drew Dixon , Estefania Lopez , Shifa Ali , Rebecca Hinrichs , Bekh Bradley , Sierra Carter , Nadine J. Kaslow","doi":"10.1016/j.xjmad.2024.100048","DOIUrl":"https://doi.org/10.1016/j.xjmad.2024.100048","url":null,"abstract":"<div><p>Mindfulness-based cognitive therapy (MBCT) offers promise as a group-based intervention to alleviate posttraumatic stress disorder (PTSD) and depression symptoms in traumatized Black adults. Given the high level of barriers that exist for low-income Black adults, virtual delivery of MBCT may be helpful. This pilot randomized controlled trial assessed feasibility and acceptability of an adapted 8-week virtual MBCT group intervention for Black adults screening positive for PTSD and depression. Forty-six participants (89.3% women) recruited from an urban safety net hospital were randomized to MBCT or waitlist control (WLC). Overall feasibility was fair (70%); however, completion rates were higher for WLC than MBCT (90% vs. 54%). Group acceptability was high across quantitative and qualitative measures for study completers. Perceived barriers to psychological treatment were high (>9). While showing potential via improved coping skills and positive health changes, this intervention's success hinges on mitigating engagement barriers for future delivery; additional studies are warranted.</p></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"5 ","pages":"Article 100048"},"PeriodicalIF":0.0,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950004424000026/pdfft?md5=d8251ec0c87ea7abc5e4896b8dd7af11&pid=1-s2.0-S2950004424000026-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139473298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}