Journal of mood and anxiety disorders最新文献

{"title":"Sense of purpose and emotion regulation strategy use: A mini-review with directions for future research","authors":"Patrick L. Hill,&nbsp;Judy J. Kwak,&nbsp;Jennifer F. Beatty-Wright","doi":"10.1016/j.xjmad.2025.100133","DOIUrl":"10.1016/j.xjmad.2025.100133","url":null,"abstract":"<div><div>Individuals with a stronger sense of purpose in life consistently exhibit less anxiety and depressive symptoms, in part due to their reduced reactivity to stressful situations. However, the affective, behavioral, and cognitive mechanisms underlying these associations remain somewhat unclear. The current brief review addresses this concern with respect to how sense of purpose may be associated with emotion regulation strategy use. Although relatively nascent, the emerging literature suggests that emotion regulation strategies may be integral to living a purposeful life. Our review highlights that while some strategies, such as cognitive reappraisal, have been consistently connected to a sense of purpose, others, including situation selection, merit further attention from the research literature. The brief review concludes by highlighting directions for future research, including the observation of whether a sense of purpose relates to polyregulation, as well as how individuals employ emotion regulation strategies in their daily lives.</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"11 ","pages":"Article 100133"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144322805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practice-based research examining effectiveness of exposure-based CBT for youth in a community mental health setting","authors":"Emily M. Becker-Haimes ,&nbsp;Michal Weiss ,&nbsp;Temma Schaechter ,&nbsp;Sophia Young ,&nbsp;Amanda L. Sanchez","doi":"10.1016/j.xjmad.2025.100129","DOIUrl":"10.1016/j.xjmad.2025.100129","url":null,"abstract":"<div><div>We examined the naturalistic effectiveness of exposure-based cognitive behavioral therapy (Ex-CBT) for pediatric anxiety and obsessive-compulsive disorder in a community mental health setting. We also characterized adaptations made to Ex-CBT and whether treatment factors varied by whether youth were Medicaid recipients or not. To do so, we conducted a three-year, retrospective chart review of consecutively treated youth in an Ex-CBT treatment center embedded in a community mental health setting (<em>N</em> = 94; 72.3 % Medicaid recipients, 68.1 % female). We abstracted baseline demographic and clinical characteristics, treatment techniques delivered, and treatment process and response variables to examine whether these varied as a function of Medicaid status and identify predictors of treatment response. Medicaid youth were more racially and linguistically diverse than non-Medicaid youth; there otherwise were no differences in baseline demographic and clinical variables. Ex-CBT was delivered in more than twice as many sessions compared to typical clinical trials. Coded session data indicated a more diverse suite of techniques delivered by clinicians not typically included in Ex-CBT protocols (e.g., case management, discussion of cultural and contextual factors) alongside Ex-CBT. Techniques employed by clinicians varied by insurance status. However, response rates were comparable to those seen in clinical trials (51–70 %, depending on response definition). Receiving a higher dose of exposure predicted greater likelihood of treatment response, as did younger age and male gender; Medicaid status and racial/ethnic minority status did not predict response. Overall, data supported Ex-CBT effectiveness in this setting. Ex-CBT was adapted in ways that differed based on whether youth were Medicaid recipients or not.</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"11 ","pages":"Article 100129"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144089257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interacting immediate and long-term action regulation in suicidal behavior","authors":"Nicholas Murphy ,&nbsp;George Kypriotakis ,&nbsp;Marijn Lijffijt ,&nbsp;Sidra Iqbal ,&nbsp;Tabish Iqbal ,&nbsp;Dania Amarneh ,&nbsp;Brittany O’Brien ,&nbsp;Amanda Tamman ,&nbsp;Ynhi Thomas ,&nbsp;Nidal Moukaddam ,&nbsp;Thomas R. Kosten ,&nbsp;Lynnette A. Averill ,&nbsp;Sanjay Mathew ,&nbsp;Alan C. Swann","doi":"10.1016/j.xjmad.2025.100118","DOIUrl":"10.1016/j.xjmad.2025.100118","url":null,"abstract":"<div><h3>Background</h3><div>Suicide is a prominent cause of death across the lifespan, especially between 10 and 34 years old. Most suicides are first attempts, during crises with unpredictably fluctuating risk, arising insidiously from mechanisms related to long-term exposure to psycho-bio-social risk factors. Identifying susceptibility from interacting immediate and long-term mechanisms of action regulation could prevent suicidal crises.</div></div><div><h3>Methods</h3><div>We investigated interacting immediate and long-term regulation of action in risk for suicide. Immediate processes were assessed through affective and behavioral symptoms and a computer measure of impaired action-regulation, the Immediate Memory Task (IMT). Long-term processes included history of trauma, stress, and addictive behaviors. We used Beck Suicidal Ideation at its Worst (SSI-W) to measure global suicidal behavior. Participants were 28 survivors of medically severe suicide attempt (MSSA) within the previous 9 months compared to 23 age, sex, and diagnosis-similar psychiatric controls with previous suicidal ideation but without attempt (NA).</div></div><div><h3>Results</h3><div>MSSA was related, independent of SSI-W, to IMT impulsive responses, Internal State Scale (ISS) activation, and Lifetime Cumulative Adversity (LCA). MSSA was indirectly related, through SSI-W, to depression, aggression, alcohol-use severity and IMT stimulus discrimination. Minimization-denial of childhood trauma directly increased MSSA,but indirectly reduced apparent MSSA through reduced SSI-W reporting.</div></div><div><h3>Discussion</h3><div>MSSA combines characteristics independent of and dependent on SSI-W, reinforced by minimization/denial of childhood trauma. Stress-related hyperarousal and denial of early trauma facilitate MSSA through ISS activation, LHA, and impulsive IMT responses. These characteristics can identify individuals who, without previous suicide attempt or conventional psychiatric diagnosis, need preventive treatment of suicide risk.</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"10 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"de novo KDM5B Mutation in a Patient with Autism Spectrum Disorder and Obsessive-Compulsive Disorder: Case Report","authors":"Niki P. Sabetfakhri,&nbsp;Stephen J. Guter Jr,&nbsp;Sandra H. Reyes Pinzon,&nbsp;Olusola A. Ajilore,&nbsp;Edwin H. Cook,&nbsp;Fedra Najjar","doi":"10.1016/j.xjmad.2025.100114","DOIUrl":"10.1016/j.xjmad.2025.100114","url":null,"abstract":"<div><h3>Background</h3><div>The <em>KDM5B</em> gene encodes a lysine histone demethylase that is essential in epigenetic regulation and human development. Homozygous and compound heterozygous variants of <em>KDM5B</em> have been associated with a distinct syndrome characterized by developmental delay, intellectual disability, and dysmorphic features. However, phenotypic presentations associated with heterozygous (HET) protein-truncating variants (PTVs) have been inconsistent, ranging from moderate to severe autism spectrum disorder (ASD) and intellectual disability (ID), to some individuals being unaffected with ASD or ID.</div></div><div><h3>Case presentation</h3><div>We report a <em>de novo</em> HET PTV (NM_006618.5 c.1708 C&gt;T; p.R570X) in <em>KDM5B</em> in an 18-year-old Caucasian female patient, who presented with ASD, and then developed severe obsessive-compulsive disorder (OCD) and leading to depression and emotion dysregulation</div></div><div><h3>Conclusions</h3><div>This case suggests a potential role for HET PTVs in the <em>KDM5B</em> gene in OCD pathogenesis and marks the first report of co-occurring ASD and OCD associated with a <em>KDM5B</em> variant.</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"10 ","pages":"Article 100114"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between pre- and postpartum posttraumatic stress symptoms and maternal functioning in Black trauma-exposed women","authors":"Rebecca Lipschutz ,&nbsp;Meghna Ravi ,&nbsp;Emma C. Lathan ,&nbsp;Monica Duan ,&nbsp;Sriya Karra ,&nbsp;Shimarith Wallace ,&nbsp;Merom Arthur ,&nbsp;Abby Britt ,&nbsp;Abigail Powers ,&nbsp;Vasiliki Michopoulos","doi":"10.1016/j.xjmad.2025.100111","DOIUrl":"10.1016/j.xjmad.2025.100111","url":null,"abstract":"","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"10 ","pages":"Article 100111"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric properties and socio-demographic correlates of the Connor-Davidson Resilience Scale in three large population-based cohorts including Danish and Icelandic adults","authors":"Maria Didriksen ,&nbsp;Hilda Daníelsdottir ,&nbsp;Marín Dögg Bjarnadóttir ,&nbsp;Cassie Overstreet ,&nbsp;Karmel W. Choi ,&nbsp;Lea Arregui Nordahl Christoffersen ,&nbsp;Christina Mikkelsen ,&nbsp;Thor Aspelund ,&nbsp;Arna Hauksdóttir ,&nbsp;Edda Bjork Thordardottir ,&nbsp;Jóhanna Jakobsdóttir ,&nbsp;Gunnar Tómasson ,&nbsp;Christian Erikstrup ,&nbsp;Bitten Aagaard ,&nbsp;Mie T. Bruun ,&nbsp;Henrik Ullum ,&nbsp;Erik Sørensen ,&nbsp;Ian C. Fischer ,&nbsp;Robert H. Pietrzak ,&nbsp;Joel Gelernter ,&nbsp;Andrew J. Schork","doi":"10.1016/j.xjmad.2025.100112","DOIUrl":"10.1016/j.xjmad.2025.100112","url":null,"abstract":"<div><div>Identifying specific factors affecting psychological resilience could be instrumental in developing new therapeutic strategies for improving and maintaining mental and physical health. To achieve this, an adequate measure of psychological resilience is essential. We studied the psychometric properties of the 10-item Connor-Davidson Resilience Scale (CD-RISC-10) across three population-based cohorts. The study included adult Danish individuals in the Danish Blood Donor Study (DBDS, N = 57,031), and the Icelandic cohorts Stress-And-Gene Analysis cohort (SAGA, N = 27,236), and COVID-19 National Resilience cohort (C19-Resilience, N = 20,373). Exploratory factor analysis revealed a consistent one-factor fit across cohorts. The scale demonstrated good internal consistency (Cronbach's alpha: 0.88–0.90) and longitudinal stability (Spearman correlation coefficients in DBDS: 0.71 across 1.5 years, 0.66 across two years). Mean CD-RISC-10 scores were consistent with previously reported scores in European populations. Lower scores were observed among participants with probable major depressive disorder, and higher scores were found with increasing age. Further evidence for construct validity was revealed as CD-RISC-10 scores moderated the association between financial trouble and depressive symptoms across all cohorts. Psychometric properties of the CD-RISC-10 were similar among women and men. Our findings support the use of the CD-RISC-10 as a reliable and valid unidimensional measure of psychological resilience in Danish and Icelandic populations.</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"10 ","pages":"Article 100112"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced neural activation during positive social approach is associated with better response to approach avoidance training for social anxiety disorder","authors":"Christopher Hunt ,&nbsp;Morgan M. Caudle ,&nbsp;Martin P. Paulus ,&nbsp;Murray B. Stein ,&nbsp;Charles T. Taylor ,&nbsp;Jessica Bomyea","doi":"10.1016/j.xjmad.2025.100110","DOIUrl":"10.1016/j.xjmad.2025.100110","url":null,"abstract":"<div><h3>Introduction</h3><div>Accumulating evidence suggests that social anxiety disorder (SAD) is characterized by diminished approach of positive social stimuli. Approach-positive approach-avoidance training (AP-AAT) may reduce this bias, but its results have been mixed. AP-AAT might be more effective for patients with deficits in the neural approach processes AP-AAT targets. Here, we attempted to identify neural areas underlying reduced approach of positive social stimuli in SAD and explore whether activity in such areas predicted response to AP-AAT.</div></div><div><h3>Method</h3><div>This was a secondary analysis of an AP-AAT clinical trial involving 40 SAD participants and 22 healthy controls (HCs). A social approach-avoidance task was completed during fMRI to identify neural activation differences between SAD and HC subjects when approaching positive social cues. SAD participants were then randomized to AP-AAT (<em>n</em> = 18) or sham training (<em>n</em> = 22). Treatment response was assessed by changes in positive affect and social connection from pre-to-post treatment.</div></div><div><h3>Results</h3><div>Compared to HCs, SAD patients exhibited significantly less activation in the left paracentral lobule (PCL), right superior parietal lobule (SPL), and left lingual gyrus (LG) when approaching relative to avoiding positive social cues. Lower activation in the right SPL (b=-7.15, p = .022) and left LG (b=-6.93, p = .007) during social approach versus avoidance predicted greater improvement in positive affect (but not social connection) in the AP-AAT group relative to sham.</div></div><div><h3>Conclusions</h3><div>Lower neural activation during positive social approach at baseline predicted better AP-AAT response. AP-AAT may be particularly well-suited to SAD patients exhibiting the neural approach deficits that the treatment putatively targets.</div></div><div><h3>ClinicalTrials.gov Identifier</h3><div>NCT02136212</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"10 ","pages":"Article 100110"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial discrimination and anxiety in African American youth: Risk, resilience, and intervention","authors":"Joya N. Hampton-Anderson ,&nbsp;Briana Woods-Jaeger ,&nbsp;Troy B. Maxwell ,&nbsp;W. Edward Craighead","doi":"10.1016/j.xjmad.2025.100115","DOIUrl":"10.1016/j.xjmad.2025.100115","url":null,"abstract":"<div><div>Among African American youth, experiences of discrimination are related to having an anxiety disorder with significant impairment. Although incorporating culturally relevant treatment components (e.g., race socialization) that address experiences of discrimination might better serve minority youth, current evidence based interventions for anxiety in outpatient settings typically fail to include those culturally relevant components. This manuscript, noting the role of racial discrimination, outlines indicators of risk and resilience for diagnosis and prognosis of anxiety disorders among African American youth. Qualitative examples, provided from a sample of community stakeholders and African American youth seeking services for an anxiety disorder, describe specific associations between experiences of racial discrimination and anxiety. We conclude that identification and inclusion of culturally specific risk and protective factors in the development, implementation, and evaluation of anxiety-focused intervention programs in outpatient settings that target culturally specific protective factors will better serve African American youth experiencing anxiety disorders.</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"10 ","pages":"Article 100115"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applying large language models to stratify suicide risk using narrative clinical notes","authors":"Thomas H. McCoy ,&nbsp;Roy H. Perlis","doi":"10.1016/j.xjmad.2025.100109","DOIUrl":"10.1016/j.xjmad.2025.100109","url":null,"abstract":"<div><div>We investigated whether large language models can stratify risk for suicide following hospital discharge. We drew on a very large cohort of 458,053 adults discharged from two academic medical centers between January 4, 2005 and January 2, 2014, linked to administrative vital status data. From this sample, each of the 1995 individuals who died by suicide or accident was matched with 5 control individuals on the basis of age, sex, race and ethnicity, admitting hospital, insurance, comorbidity index, and discharge year. We applied a HIPAA-compliant large language model (gpt-4–1106-preview) to estimate risk for suicide based on narrative discharge summaries. In the resulting cohort (n = 11,970), median age was 57 (IQR 44 –76); 4536 (38 %) were women; 348 (3 %) had a primary psychiatric admission diagnosis. For the model-predicted risk, time to 90 % survival was 1588 days (IQR 1374–1905) in the lowest-risk quartile, 1432 (IQR 1157–1651) in the 2nd quartile, 661 (IQR 538–820) in the 3rd quartile, and 302 (IQR 260–362) in the top quartile (p &lt; .001). In Fine and Gray competing risk regression, predicted hazard was significantly associated with observed risk (unadjusted HR 7.66 [95 % CI 6.40–9.27]; adjusted for sociodemographic features and utilization, HR 8.86 (7.00–11.2)). Estimated risks were significantly greater scores among individuals who were Black or Hispanic (p &lt; .005 for each, versus white individuals). Overall, a large language model (LLM) was able to stratify risk for suicide and accidental death among individuals discharged from academic medical centers beyond that afforded by simple sociodemographic and clinical features medical centers.</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"10 ","pages":"Article 100109"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An examination of symptoms, function and quality of life as conjoint clinical outcome domains for treatment-resistant depression","authors":"Charles R. Conway ,&nbsp;A. John Rush ,&nbsp;Charles Gordon ,&nbsp;Sheldon H. Preskorn ,&nbsp;Harold A. Sackeim ,&nbsp;Scott T. Aaronson ,&nbsp;Roger S. McIntyre ,&nbsp;Ying-Chieh (Lisa) Lee ,&nbsp;Olivia Shy ,&nbsp;Quyen Tran ,&nbsp;Jeffrey Way ,&nbsp;Mark T. Bunker","doi":"10.1016/j.xjmad.2025.100121","DOIUrl":"10.1016/j.xjmad.2025.100121","url":null,"abstract":"<div><h3>Objective</h3><div>The treatment of depression aims to improve depressive symptoms, daily function and quality of life (QoL). These exploratory analyses of a database of convenience from the RECOVER trial evaluated how a “tripartite” metric based on these 3 outcome domains might perform in treatment-resistant depression (TRD).</div></div><div><h3>Methods</h3><div>Outcome domains included depressive symptoms (MADRS, QIDS-C, QIDS-SR), function (WPAI item-6) and QoL (Mini-Q-LES-Q) obtained at months 3, 6, 9 and 12 in outpatients with markedly TRD in the double-blind RECOVER trial that compared sham to active adjunctive vagus nerve stimulation (VNS). For each domain, clinically meaningful differences were defined <em>a priori</em>. Analyses addressed 3 questions: 1) Does each domain detect meaningful benefits undetected by the other domains? 2) Is the tripartite metric validated by an independent clinician-rated global index of improvement (CGI-I)? 3) How well does the tripartite metric detect treatment group differences in the RECOVER trial?</div></div><div><h3>Results</h3><div>Clinically meaningful reductions in depressive symptoms alone missed 25–51 % of all participants who evidenced clinically meaningful benefits in depressive symptoms, function or QoL. The tripartite metric strongly correlated with CGI-I ratings (tetrachoric r = 0.73–0.85), with stronger relationships than each component individually. The tripartite metric successfully separated active from sham adjunctive VNS in a 1-year trial of patients with markedly TRD.</div></div><div><h3>Conclusion</h3><div>Symptoms, function and QoL capture distinct, clinically significant and valid outcomes that identify persons with markedly TRD with a range of clinically meaningful benefits. Whether these results pertain to other major depressive disorder patient groups and treatments deserves study.</div></div>","PeriodicalId":73841,"journal":{"name":"Journal of mood and anxiety disorders","volume":"10 ","pages":"Article 100121"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}