Journal of dentistry (Shiraz, Iran)最新文献

{"title":"Biomimetic Scaffolds for Regeneration of Temporomandibular Joint Disc: A Narrative Review.","authors":"Hojat Rezazadeh, Nazafarin Samiraninezhad, Mostafa Rezaee","doi":"10.30476/dentjods.2023.97625.2024","DOIUrl":"10.30476/dentjods.2023.97625.2024","url":null,"abstract":"<p><p>Defects and dysfunctions of temporomandibular joint (TMJ) disc are responsible for the majority of TMJ diseases. Current treatments in this matter are usually short-term and only palliative, thus an alternative treatment that offers long-lasting repair is in great demand. In recent years great attempts have been made to prepare an ideal scaffold, which best resembles the native TMJ disc in characteristics such as mechanical, physical and biological properties. This narrative review focuses on developments of the recent ten years in fabrication of scaffolds using decellularized tissues, natural and synthetic biomaterials for regeneration of TMJ disc and compared their properties. PubMed and Google Scholar databases were searched using the following keywords (\"TMJ\" OR \"temporomandibular joint\" OR \"TMD\" OR \"temporomandibular disease\") AND (\"scaffold\" OR \"hydrogels\"). Randomized controlled trials, randomized clinical trials, case-controls, case reports, and animal studies were included. Comments, systematic reviews, meta-analyses, and non-English papers were excluded. The study concluded that hybrid scaffolds have exhibited favorable cell attachment and proliferation. Synthetic scaffolds have shown promise in providing better control over structural properties; however, additional processes are often required to provide biomimetic cell signaling. While there is still much to learn about the ideal scaffold for TMJ disc regeneration, both natural and synthetic scaffolds have shown promise in achieving the functional, structural, biological, and mechanical properties of a native TMJ disc.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"108-117"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Dental Caries Risk Assessment Using CaRisk- A Simple Mobile Based Application and WHO deft, DMFT Scores: A Cross Sectional Study.","authors":"Canty Sandra S, Aparna S, Parangimalai Diwakar Madan Kumar","doi":"10.30476/dentjods.2023.98075.2051","DOIUrl":"10.30476/dentjods.2023.98075.2051","url":null,"abstract":"<p><strong>Statement of the problem: </strong>It is essential to address caries risk at an early stage for the prevention of dental caries. Mobile application CaRisk is designed in a particular way to self-assess the dental caries risk by the individual's themselves.</p><p><strong>Purpose: </strong>The current study aimed to assess the dental caries risk among age groups 5-6 and 35-44 using self-assessment caries risk mobile application CaRisk and compare it with the deft and DMFT values.</p><p><strong>Materials and method: </strong>This cross-sectional study was conducted in Chennai, India; to evaluate the risk of dental caries in children aged 5 to 6 and adults aged 35 to 44. The scores of the mobile application CaRisk and the decayed- extracted- filled teeth (deft)/ decayed-missing-filled-teeth (DMFT) caries risk assessment were evaluated. Descriptive statistics were performed. The risk category was determined by frequency. Chi-square analysis was done to determine whether the DMFT scores and the CaRisk mobile app were associated. The correlation was performed between the CaRisk mobile application and DMFT scores.</p><p><strong>Results: </strong>Association was found between the caries risk assessment score of the mobile application CaRisk and the DMFT and deft scores of the adults and children for both the age groups 5-6 and 35-44 years respectively and it indicates that it was found to be statistically significant. Pearson's correlation was performed to assess the strength of association and R-values obtained for the age group 5-6 and 35-44 years respectively, which was statistically significant (0.892 and 0.840).</p><p><strong>Conclusion: </strong>This CaRisk mobile application scores correlate with the deft and DMFT scores and it is an effective self-diagnosis tool for assessing dental caries risk assessment. Further, it is suggested that the mobile application CaRisk should be tested among a huge population.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"138-146"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Odontogenic Tumors: A Challenge for Clinical Diagnosis and an Opportunity for AI Innovation.","authors":"Mohamad Reza Golzar Feshalami, Mehraban Shahi, Nasrin Davari Dolatabadi","doi":"10.30476/dentjods.2024.101237.2284","DOIUrl":"10.30476/dentjods.2024.101237.2284","url":null,"abstract":"","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"95-96"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial.","authors":"Mohammad Mehdi Torabi, Reyhaneh Shoorgashti, Farnaz Haji Fattahi, Simin Lesan","doi":"10.30476/dentjods.2023.97675.2032","DOIUrl":"10.30476/dentjods.2023.97675.2032","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Gag reflex is among the most common problems during dental and endoscopic procedures. Benzydamine hydrochloride is a non-steroidal anti-inflammatory medication and a local anesthetic that might be useful in reducing the gag reflex.</p><p><strong>Purpose: </strong>This study aimed to evaluate the effects of benzydamine hydrochloride mouthwash on the intensity of the gag reflex.</p><p><strong>Materials and method: </strong>In this randomized clinical trial study, 30 participants aged 21-26 with a gag trigger point index (GTPI) higher than 2 were divided into 2 groups. In the case group, 15 ml of 0.15% benzydamine hydrochloride mouthwash was gargled for 1 minute, and after 10 minutes GTPI test was conducted. In the control group, 4 puffs of 10% lidocaine spray were applied to the mucosa of the targeted area, and after 5 minutes, GTPI was measured. Participants were asked about the taste and smell of the medications.</p><p><strong>Results: </strong>GTPI was significantly reduced in both groups. In the lidocaine group, the GTPI score changed from 4.47 to 2.00 (<i>p</i>< 0.001), and that for the benzydamine group was 4.20 to 1.47 (<i>p</i>< 0.001). The variance rate of the gag reflex was -2.73 and -2.47 in the benzydamine group and lidocaine group, respectively. However, this reduction was not statistically significant between the two groups. Moreover, benzydamine mouthwash has a significantly better taste and smell than lidocaine (<i>p</i>= 0.001).</p><p><strong>Conclusion: </strong>The results of this study showed that benzydamine mouthwash could be used quite effectively in reducing the gag reflex.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"162-168"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two Palatal Roots in Maxillary First Molar, a Rare Entity: Report of Two Cases.","authors":"Vineeta Nikhil, Padmanabh Jha, Preeti Mishra, Sonal Sahu, Abhishek Bhargava","doi":"10.30476/dentjods.2023.98649.2101","DOIUrl":"10.30476/dentjods.2023.98649.2101","url":null,"abstract":"<p><p>An in-depth understanding of the anatomical variations of maxillary molars is essential for endodontic success. Unlike the maxillary second molars, the presence of a second palatal root is uncommon in the first maxillary molar. This case report describes two cases of non-surgical management of maxillary molars with extra palatal roots. Careful clinical examination, knowledge of the internal anatomy, and the use of advanced radiographic modalities like cone beam computed tomography (CBCT) can reveal the presence of variations in the internal and external anatomy of any tooth. Therefore, for nonsurgical as well as surgical management clinicians should always watch out for any deviations in a tooth and utilize all the available tools to diagnose and manage them successfully.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"178-182"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cone-Beam Computed Tomography-Based Evaluation of Root Dilaceration in Permanent Premolars: A Retrospective Study.","authors":"Bahar Asheghi, Safoora Sahebi, Zeinab Rafiee, Maryam Zangooei Booshehri, Afsane Habibi","doi":"10.30476/dentjods.2023.98244.2067","DOIUrl":"10.30476/dentjods.2023.98244.2067","url":null,"abstract":"<p><strong>Statement of the problem: </strong>As a developmental disorder characterized by an abnormal bend and angle in the longitudinal axis of the tooth root, dilaceration can cause complications in routine dental procedures such as endodontics, orthodontics, and surgical treatments.</p><p><strong>Purpose: </strong>The purpose of this study was to investigate the prevalence of dilaceration in maxillary and mandibular premolar teeth in a population of Shiraz city based on cone-beam computed tomography (CBCT).</p><p><strong>Materials and method: </strong>This is a retrospective cross-sectional study on 927 premolar teeth and 132 CBCT radiographs of patients obtained from four private radiology clinics in Shiraz (Iran). In this study, the presence, location, direction, and severity of dilaceration in premolar roots as well as its relationship with gender were investigated. Chi-square and Fisher tests were used to analyze the data.</p><p><strong>Results: </strong>The results showed that 17% of the studied 927 teeth had dilaceration. The prevalence of dilaceration was significantly higher in women than in men (20.3% vs. 13.6%, <i>p</i>= 0.005). The dilaceration rates were significantly higher in the mandibular first and second premolar teeth (31.6% and 26%, <i>p</i>= 0.002) than in the other teeth. In addition, the highest prevalence was in the distal direction with mild severity in the apical third of the root (<i>p</i>< 0.001).</p><p><strong>Conclusion: </strong>According to the results of this study, the prevalence of dilaceration was relatively high in mandibular premolar teeth especially in women.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"155-161"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Acceptable Range of Lips and Chin Position in Two Different Geographical Zones of Iran among Laypersons.","authors":"Farzaneh Golfeshan, Athar Nasseri Mojarad, Ahmad Reza Sardarian","doi":"10.30476/dentjods.2023.97251.2003","DOIUrl":"10.30476/dentjods.2023.97251.2003","url":null,"abstract":"<p><strong>Statement of the problem: </strong>The position of the chin and lips are important components in the lower third of the face and can be changed by orthodontic treatment. It seems that factors such as diversity in culture, ethnicity, and place of residence are among the factors affecting people's perception of beauty. Iran, as a vast country, contains different ethnicities and cultures, and of course, it is not exempt from this point of view.</p><p><strong>Purpose: </strong>Our purpose of conducting this study is to investigate the impact of the difference in living environment and culture on people's aesthetic perception. Orthodontists and oral surgeons can use these data to choose the best treatment plan for the patients according to their geographical zones.</p><p><strong>Material and method: </strong>A descriptive cross-sectional study was conducted to evaluate the perception of lips and chin position. A series of 25 profile images were prepared in 5 sets. Each set contained 5 profile images. Northern and Southern lay people and orthodontists were asked to evaluate the profile series of each set in 1 session and score them from 1 to 5: 1, very unattractive; 2, unattractive; 3, neither attractive nor unattractive; 4, attractive; or 5, very attractive.</p><p><strong>Results: </strong>652 participants in 3 groups, including 16 orthodontists (10 men and 6 women), 318 lay people of the North of Iran (172 men and 138 women), and 318 lay people of the South of Iran (175 men and 139 women) participated in this study. Regardless of the chin position, normal lip position and slight changes of that (in both protruded and retruded positions) were more favorable for all three groups. The images with moderately retruded lips were scored as the least attractive by all three groups and orthodontist gave the lowest score to these profiles. Southern people could better tolerate moderately retruded lips than other two groups. In the fifth series, orthodontists preferred slightly and moderately protruded lips in comparison to other two groups of laypeople.</p><p><strong>Conclusion: </strong>Regardless of the chin position, normal and slightly (-2mm to +2mm) protruded and retruded lips were more favorable in all three groups. Southern people could better tolerate moderately retruded lips than the two other groups.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"169-177"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Platelet Concentrates in Dental-Pulp Regeneration: A Systematic Review of Randomized Clinical Trials.","authors":"Zahra Kiaipour, Mahdieh Shafiee, Ghassem Ansari","doi":"10.30476/dentjods.2023.96000.1912","DOIUrl":"10.30476/dentjods.2023.96000.1912","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Treatment of immature necrotic teeth is a problematic situation. Conventional root canal therapy is challenging and leaves a weak, fragile, and undeveloped tooth for lifetime.</p><p><strong>Purpose: </strong>This review was aimed to assess the outcome of available randomized clinical trials (RCTs) on the efficacy of platelet concentrates (PC) in dentine-pulp complex regeneration.</p><p><strong>Materials and method: </strong>In this systematic review, an electronic search was conducted on MEDLINE, EMBASE, Cochrane, and Google scholar databases. A further manual search was performed on the list of related articles in order to ensure inclusion of potentially missed articles in earlier electronic search. Those proved RCTs matched with the standard criteria were included following an initial assessment of abstracts and the text independently by the reviewers.</p><p><strong>Results: </strong>From the total 602 harvested articles, only 13 met the criteria and were evaluated with 11 having parallel design and 2 split mouth. Only one study featured low risk of bias, while three had moderate risk and the rest were at high risk of bias. Six studies had used platelet rich plasma (PRP), 4 employed platelet rich fibrin (PRF), one utilized injectable platelet rich fibrin (I-PRF), and three used both PRF and PRP for their experimental groups while blood clot (BC) was used as the control group for all. The success rate was reported at 87.3% judged by the absence of pathologic signs and symptoms.</p><p><strong>Conclusion: </strong>Dentin wall thickening, root lengthening and apex closure were higher in PC groups, however, these differences were not statistically significant in reported studies. It can be concluded that PCs promote the pulp tissue revitalization and continuation of root development. However, a consensus on its potency for true pulp regeneration is yet to be reached.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"97-107"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of a Localized Stage III Periodontitis in the Esthetic Zone with Guided Tissue Regeneration Technique on a Heavy Smoker Patient with 12-Year Follow- up: A Case Report.","authors":"Fatme Mouchref Hamasni, Fady El Hajj","doi":"10.30476/dentjods.2024.100483.2224","DOIUrl":"10.30476/dentjods.2024.100483.2224","url":null,"abstract":"<p><p>This case report exhibits a heavy smoker female patient with a localized stage III periodontitis who has been under the smoking cessation program during the pre-surgical period, followed by a strict maintenance program for the past twelve years, after being treated with guided tissue regeneration techniques and restored with zirconia prosthetic crowns. A 50-year-old, heavy smoker (> 40 cigarettes per day), systemically healthy female patient presented complaining of mobility and pain in the upper right central incisor, which was temporarily splinted to the left central incisor using resin composite. After clinical and radiographic examination, significant damage of the attachment apparatus, deep periodontal lesions extending the middle portion of the root, and severe infrabony defect were noted. Following the initial hygienic phase, a guided tissue regeneration surgery using xenograft bone substitute covered by a resorbable collagen membrane was performed. After six months of healing, four zirconia crowns were cemented on the central and lateral incisors based on patient esthetic compliance. During the 12-year follow-up period, neither residual pockets nor gingival recession were observed, and perfect marginal bone stability, and esthetic and functional results were noted. This case shows the predictability of a conservative surgical technique, the guided tissue regeneration, based on appropriate treatment planning and a strict maintenance program. It also demonstrates the importance of at least a 6-month healing period after such surgeries, allowing complete tissue maturation and a re-establishment of the supra osseous gingival tissues in order to locate the prosthetic margins without interfering with the soft tissues integrity.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"183-189"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computer Assisted Bone Age Estimation Using Dimensions of Metacarpal Bones and Metacarpophalangeal Joints Based on Neural Network.","authors":"Abdolaziz Haghnegahdar, Hamid Reza Pakshir, Mojtaba Zandieh, Ilnaz Ghanbari","doi":"10.30476/dentjods.2023.95629.1882","DOIUrl":"10.30476/dentjods.2023.95629.1882","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Bone age is a more accurate assessment for biologic development than chronological age. The most common method for bone age estimation is using Pyle and Greulich Atlas. Today, computer-based techniques are becoming more favorable among investigators. However, the morphological features in Greulich and Pyle method are difficult to be converted into quantitative measures. During recent years, metacarpal bones and metacarpophalangeal joints dimensions were shown to be highly correlated with skeletal age.</p><p><strong>Purpose: </strong>In this study, we have evaluated the accuracy and reliability of a trained neural network for bone age estimation with quantitative and recently introduced related data, including chronological age, height, trunk height, weight, metacarpal bones, and metacarpophalangeal joints dimensions.</p><p><strong>Materials and method: </strong>In this cross sectional retrospective study, aneural network, using MATLAB, was utilized to determine bone age by employing quantitative features for 304 subjects. To evaluate the accuracy of age estimation software, paired t-test, and inter-class correlation was used.</p><p><strong>Results: </strong>The difference between the mean bone ages determined by the radiologists and the mean bone ages assessed by the age estimation software was not significant (<i>p</i> Value= 0.119 in male subjects and <i>p</i>= 0.922 in female subjects). The results from the software and radiologists showed a strong correlation -ICC=0.990 in male subjects and ICC=0.986 in female subjects (<i>p</i>< 0.001).</p><p><strong>Conclusion: </strong>The results have shown an acceptable accuracy in bone age estimation with training neural network and using dimensions of bones and joints.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 1","pages":"51-58"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10963864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}