Journal of dentistry (Shiraz, Iran)最新文献

{"title":"Calcifying Odontogenic Cyst in Posterior Maxilla: A Case Report.","authors":"Farhad Ghorbani, Mohammad Amin Amiri, Mohammad Mehdi Farahmand, Saeed Afzoun, Maryam Paknahad","doi":"10.30476/dentjods.2024.102636.2375","DOIUrl":"https://doi.org/10.30476/dentjods.2024.102636.2375","url":null,"abstract":"<p><p>In the present study, we reported a 66-year-old woman with an uncommonly painful calcifying odontogenic cyst (COC) in the posterior region of the left side of the maxilla. The cyst was evaluated radiographically and histopathologically. The present case showed a multilocular cyst with a mixed internal structure. The most noticeable effects on the peripheral structures were elevated maxillary sinus floor, osteomeatal complex, and nasal obstruction. To better understand the impact of COC on the trabecular pattern of the surrounding bone, we performed fractal analysis on the panoramic images pre- and post-operatively. The expansion of COC can change the trabecular pattern, which subsequently can change the fractal dimension of the area. After histopathological confirmation of the diagnosis, the cyst was surgically removed.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"88-94"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> Relative Gene Expressions and Oral Squamous Cell Carcinoma.","authors":"Hamideh Kadeh, Tayebeh Baranzehi, Milad Mollaali, Neda Maserat, Mohammad Javad Shahraki, Dor Mohammad Kordi-Tamandani","doi":"10.30476/dentjods.2024.100237.2205","DOIUrl":"https://doi.org/10.30476/dentjods.2024.100237.2205","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Oral squamous cell carcinoma (OSCC) is the eighth leading cause of cancer-related death worldwide. <i>JAK2</i> and <i>STAT3</i> primarily influence intrinsic tumor cell behavior, and <i>CTLA4</i> impacts the interplay between the tumor and the host immune system in the context of cancers. There is scarce information regarding the involvement and roles of <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> genes in OSCC; however, the molecular mechanisms are still unclear.</p><p><strong>Purpose: </strong>This study examined the relationship between <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> gene expression levels and OSCC in a group of patients in the southeast of Iran.</p><p><strong>Materials and method: </strong>This cross-sectional study was conducted in which the relative gene expression levels of <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> were compared between 23 oral paraffin tissue blocks collected from OSCC patients and 20 fresh gingival tissues collected from healthy individuals. The Real-Time quantitative PCR (RT-qPCR) assay was employed to assess relative gene expression levels. SPSS 27 was employed to perform statistical analyses.</p><p><strong>Results: </strong>Significant differences were found between OSCC patients and healthy individuals concerning gene expression levels of <i>JAK2</i> (2.4-fold, <i>p</i>< 0.0001), <i>STAT3</i> (2.32-fold, <i>p</i>< 0.0001), and <i>CTLA4</i> (4.09-fold, <i>p</i>< 0.0001). Additionally, there were significant positive correlations among <i>JAK2-STAT3</i> (ρ= 0.667, <i>p</i>< 0.001), <i>JAK2-CTLA4</i> (ρ= 0.771, <i>p</i>< 0.001), and <i>STAT3-CTLA4</i> (ρ= 0.635, <i>p</i>= 0.001) co-expressions. Moreover, gender, age groups, and tumor locations did not significantly correlate with the expression levels of these genes (<i>p</i>> 0.05). Nevertheless, significant differences occurred between histopathological grades and the gene expression levels of <i>JAK2</i> (<i>p</i>< 0.001), <i>STAT3</i> (<i>p</i>= 0.001), and <i>CTLA4</i> (<i>p</i>< 0.001).</p><p><strong>Conclusion: </strong>The overexpression of <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> can be considered triggers for OSCC development. It may be beneficial to conduct future research on OSCC by considering downstream genes involved in the <i>JAK2</i>/<i>STAT3</i>/<i>CTLA4</i> axis.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"25-32"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress Distribution and Tooth Displacement Analysis of Maxillary Molar Distalization by Different Designs of Jig in a Finite Element Study.","authors":"Hooman Zarif Najafi, Hamid Reza Pakshir, Faezeh Bahraini","doi":"10.30476/dentjods.2024.100556.2230","DOIUrl":"https://doi.org/10.30476/dentjods.2024.100556.2230","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Despite the prevalence of CLII malocclusion, still the best mechanotherapy for non-extraction treatment is not verified.</p><p><strong>Purpose: </strong>The aim of the present study was to evaluate the stress distribution and tooth displacement during maxillary molar distalization with the aid of two different constructions of jigs in three different lever arm heights.</p><p><strong>Materials and method: </strong>In this finite element study, models were meticulously constructed to represent the maxillary arch teeth (excluding the third molar), periodontal ligament, alveolar bone, maxillary brackets, main archwire, molar bands, jigs, and mini screws. These models were imported into Ansys software for simulation and analysis. Two different jig configurations with three different lever arm height were created. A 150-gram force was applied to simulate tooth movement, facilitate observation, and analyze its effects on oral components.</p><p><strong>Results: </strong>In various experimental configurations involving tow jigs with differing lever arm heights, the central incisor exhibited displacement characterized by lingual and distal crown tipping, along with evidence of intrusion. Concurrently, the first molar displayed lingual and distal tipping, as well as extrusion, across six distinct modalities.</p><p><strong>Conclusion: </strong>In the main, posterior teeth showed distal and lingual tipping and extrusion and anterior teeth demonstrated intrusion mesial and lingual tipping in all models. It seems the differences were due to different lever arm heights. Two types of jig had no significant effect on stress distribution and tooth movement.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"33-47"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the Effectiveness of GLUMA and 940 nm Laser for Improving Crown Retention with Self-Adhesive Cement.","authors":"Pantea Amiri, Ghazale Tekie, Arash Azizi, Shirin Lawaf","doi":"10.30476/dentjods.2024.99630.2165","DOIUrl":"https://doi.org/10.30476/dentjods.2024.99630.2165","url":null,"abstract":"<p><strong>Statement of the problem: </strong>The retention of dental crowns plays a pivotal role in their long-term success and maintenance. According to the ongoing controversy about the effect of GLUMA desensitizer and diode laser on the retention of full metal crowns, this study seeks to investigate the effectiveness of two different methods in enhancing the bond strength of full-metal crowns.</p><p><strong>Purpose: </strong>This study was developed to compare the effect of 940nm diode laser and GLUMA desensitizer on the bond strength of full-metal crowns cemented by self-adhesive resin cement (RelyX U200).</p><p><strong>Materials and method: </strong></p><p><strong>Results: </strong>Crown retention in the 940 nm diode laser group (166.86±34.25 N) was significantly lower than the GLUMA desensitizer group (318.59±56.31 N) (<i>p</i>< 0.05), but there was no significant difference with the control group (138.17±40.81). Crown retention in the GLUMA desensitizer group was significantly higher than the other groups (<i>p</i>< 0.05).</p><p><strong>Conclusion: </strong>Results of this study showed that GLUMA desensitizer had a positive effect, and 940nm diode laser had no effect on the retention of crowns cemented by self-adhesive resin cement.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"61-68"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Technique to Retrieve Cement Retained Implant Supported Prosthesis with Digital Imaging: A Technical Report.","authors":"Kapil Raju, Fathima Banu Raza, Anand Kumar V","doi":"10.30476/dentjods.2024.101241.2285","DOIUrl":"https://doi.org/10.30476/dentjods.2024.101241.2285","url":null,"abstract":"<p><p>Retrievability of cement-retained implant-supported prosthesis in the event of abutment screw loosening is a challenging task, and the most common arbitrary drilling technique to retrieve the prosthesis can cause extensive irreversible damage. A 37-year-old male patient reported a chief complaint of a mobile implant-supported prosthesis in the left upper back tooth region. Past dental history revealed that the patient had underwent replacement of missing 27 using cement-retained implant-supported prosthesis 4 years ago using digital impression technique and Computer Aided Designing-Computer Aided Manufacturing (CAD-CAM) milling. This case report describes a novel technique to locate the screw access channel and fabrication of three-dimensional (3D) printed guide template that retrieved the cement-retained prosthesis utilizing the stored digital imaging data. The technique involves designing of the virtual model, screw access channel locator, and prosthesis using CAD technology with the digital impression made during prosthesis fabrication.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"95-98"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic Resistance to <i>Pseudomonas Aeruginosa</i> in the Saliva of Candidates of Bone Marrow Transplantation.","authors":"Maryam Zahed, Mojtaba Safvat, Abdollah Bazargani, Janan Ghapanchi, Zahra Ranjbar","doi":"10.30476/dentjods.2024.100492.2225","DOIUrl":"https://doi.org/10.30476/dentjods.2024.100492.2225","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Opportunistic infections such as <i>Pseudomonas aeruginosa</i>, colonized from the oral cavity, are common in candidates of bone marrow transplantation. Therefore, it is important to prescribe appropriate antibiotics for this group of debilitated patients.</p><p><strong>Purpose: </strong>In this study, we aimed to investigate the antibiotic resistance to <i>Pseudomonas aeruginosa</i> encountered in candidates of bone marrow transplantation referred to Imam Reza Clinic, Namazi Hospital, and Amir Hospital, Shiraz, Iran.</p><p><strong>Materials and method: </strong>This cross-sectional study was performed on 30 patients with leukemia and lymphoma. To identify Pseudomonas species, saliva samples were collected and cultured in a blood agar medium. Considering the present therapies, we examined the antibiotic sensitivity of Penicillin, Oxacillin, Gentamicin, Tetracycline, Cefepime, Ciprofloxacin, Imipenem, Ceftazidime, Cefotaxime, Erythromycin, Trimethoprim, Sulfamethoxazole, and Vancomycin. Statistical analysis was performed using chi-square test (χ²) and SPSS software. The <i>p</i> Value< 0.05 was considered significant.</p><p><strong>Results: </strong>In 10 patients out of 30 for whom <i>Pseudomonas aeruginosa</i> was found positive (33.33%), all cultures were resistant to Penicillin and Oxacillin (100%), followed by Trimethoprim and Sulfamethoxazole (80%). The best performance was seen by Vancomycin (20%). No correlation was found in terms of age, gender, and type of disease (lymphoma or leukemia) for antibiotic resistance (<i>p</i>> 0.05).</p><p><strong>Conclusion: </strong>It seems that Penicillin, Oxacillin, Tetracycline, Sulfamethoxazole have significant resistance to Pseudomonas aeruginosa. Further research on Gentamicin, Ceftazidime, Ciprofloxacin, and especially Vancomycin is recommended for effective antibiotic prescriptions against <i>Pseudomonas aeruginosa</i>.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"17-24"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prevalence of Temporomandibular Disorder in Iran: A Literature Review.","authors":"Sajad Ghorbanizadeh, Kamran Azadbakht, Hamid Badrian, Nakisa Torabinia","doi":"10.30476/dentjods.2024.101406.2297","DOIUrl":"https://doi.org/10.30476/dentjods.2024.101406.2297","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Temporomandibular joint disorder (TMD) will appear if there is a problem with the temporomandibular joint, bones, related muscles, or ligaments. This complication causes severe joint pain near the ears, head, neck, and jaws. TMD has been reported to affect 40 to 70% of adults.</p><p><strong>Purpose: </strong>Based on previous studies, the present review aimed to determine the prevalence of TMD among the Iranian population.</p><p><strong>Materials and method: </strong>This review and meta-analysis was performed according to the PRISMA guidelines. All relevant studies published during 2000-2023 were retrieved by a systematic search in available international databases, including Web of Science, Science Direct, Scopus, PubMed, and Google Scholar, and domestic Persian databases, including SID, Magiran, and Iran Medex. Finally, 22 completely related studies were selected to investigate the main objective. The Comprehensive Meta-analysis (CMA) software was used for data analysis in this systematic review.</p><p><strong>Results: </strong>Initially, 212 articles were retrieved, of which 116 were duplicate studies. Further, 39 studies were excluded after evaluation of the title and abstract, and 35 studies were excluded after considering the inclusion and exclusion criteria. Finally, 22 articles were included in the meta-analysis. The pooled prevalence of TMD in Iran was 0.56 (0.44-0.68).</p><p><strong>Conclusion: </strong>In general, the prevalence of TMD in the Iranian population is relatively high. Therefore, it is necessary to develop strategies to educate people, especially those at risk. Furthermore, due to the presence of TMD in children and students in some parts of the country, it is necessary to perform essential examinations in preschools to prevent the development of this disorder in later life.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Sleep Quality and Periodontal Status: A Case-Control Study.","authors":"Fatemeh Kamalian Mehrizi, Ameneh Hosseini Yekani, Fahimeh Rashidi Maybodi","doi":"10.30476/dentjods.2024.101184.2278","DOIUrl":"https://doi.org/10.30476/dentjods.2024.101184.2278","url":null,"abstract":"<p><strong>Statement of the problem: </strong>In the literature, the relationship between sleep quality and periodontal diseases has been mentioned, but still there is a lack of consensus and a valid conclusion in the results obtained.</p><p><strong>Purpose: </strong>This study aimed to compare the sleep quality of patients with periodontitis and their healthy counterparts. The correlation between sleep quality score and age, gender, occupation, brushing pattern, and the severity of periodontal disease was also investigated.</p><p><strong>Materials and method: </strong>This case-control study was conducted on 106 patients with periodontitis and 106 controls with healthy periodontium referring to the Periodontology Department of Yazd Dental School from December 2021 to April 2022. The sleep quality of the two groups was assessed by the Pittsburgh Sleep Quality Index (PSQI). Data were analyzed by ANOVA, t-test, and linear regression to assess possible correlations between the sleep quality score and demographic variables, tooth brushing pattern, and presence of periodontitis and its severity (alpha=0.05).</p><p><strong>Results: </strong>Totally, 149 females (70.3%) and 63 males (29.7%) with the mean age of 34.17±8.29 years, participated in this study. The sleep quality score had no significant correlation with age, gender, occupation, or tooth brushing pattern (<i>p</i>> 0.05). However, the sleep quality had a significant correlation with periodontitis (OR= 1.15, CI 95%: 1.02-1.29, <i>p</i>= 0.01). The sleep quality score had no significant correlation with the severity of periodontal disease (<i>p</i>= 0.225).</p><p><strong>Conclusion: </strong>Sleep quality of patients with periodontitis was significantly lower than that of healthy controls.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"69-75"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanoparticles Induced Biomimetic Remineralization of Acid-Etched Dentin.","authors":"Devalla Venu Babu, Srinidhi V Ballullaya, Pushpa S, Neha Taufin, Pilli Sai Naveen","doi":"10.30476/dentjods.2024.98928.2117","DOIUrl":"10.30476/dentjods.2024.98928.2117","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Dentin bonding with etch-and-rinse adhesives involves demineralizing the 5-8µm of the surface dentin to create micro space for resin infiltration. The presence of continuous fluid movement in dentin tubules and positive pulpal pressure prevents complete water replacement by resin monomers. This results in areas of demineralized dentin, which contain collagen fibers without resin infiltration. The exposed collage fibers are subjected to enzymatic degradation leading to less durable hybrid layer.</p><p><strong>Purpose: </strong>The aim of this study was to evaluate the remineralizing effect of the nanoparticles on the resin dentin bonding interface.</p><p><strong>Materials and method: </strong>The three experimental remineralizing nanoparticles were characterized for their morphology, size, and composition. A total of 48 extracted non-carious human third molar teeth were sectioned at 2 mm below the cemento enamel junction. Class I cavity was prepared and the tooth samples were placed in an intra pulpal pressure simulation device. After etching of the prepared cavity, the samples were randomly divided into four groups (n=10) as follows: (1) control group(c) (n=10) (2) Nano-hydroxyapatite (nHAP) (n=10) (3) Chitosan-nanohydroxyapatite (Chi-nHAP) (n=10) (4) Mesoporous silica-hydrox-yapatite (MS-nHAP) (n=10). After 30 days remineralization period, the samples were evaluated for micro tensile bond strength, hybrid layer morphology, and mineral composition of the hybrid layer. The results were analyzed statistically by one-way ANOVA and Tukey's multiple post hoc tests.</p><p><strong>Results: </strong>Scanning electron microscopic observation of nanoparticles revealed irregular particle shapes with calcium phosphate ratio of 1.60. The zeta analyzer showed a mean diameter of 161.0 nm, 323.0nm, 185.0nm for nHAP, Chi-nHAP, and MS-nHAP respectively. Post hoc Bonferroni test revealed significantly higher bond strength for nHAP, Chi-nHAP, and MS-nHAP when compared to control group. MS-nHAP resulted in the uniform deposition of apatite crystal on the surface without any evidence of dentinal tubules openings and had higher mineral to matrix ratio compared to other groups.</p><p><strong>Conclusion: </strong>MS-nHAP nanoparticles can be considered as a reliable source of calcium and phosphate for biomimetic remineralization of hybrid layer. Application of nanoparticle remineralization precursors before application of dentin bonding agents results in remeralization of exposed collagen fibers thereby improving the clinical longevity of hybrid layer.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 4","pages":"359-368"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effect of Applying Chitosan, Neem, Tulsi, Aloe vera, and Chlorhexidine Solutions on the Shear Bond Strength of Composite to Dentin.","authors":"Farahnaz Sharafeddin, Fatemeh Aghaei","doi":"10.30476/dentjods.2023.98834.2112","DOIUrl":"10.30476/dentjods.2023.98834.2112","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Dentin adhesion is challenging and needs modifications. Newly introduced nature-derived materials may be a useful solution in improving dentin adhesion. The use of natural antimicrobial agents for pretreating prepared dentin surfaces before restoration has become of interest.</p><p><strong>Purpose: </strong>The present study investigated the effect of natural compounds on the shear bond strength (SBS) of resin composite adhesively bonded to dentin.</p><p><strong>Materials and method: </strong>Sixty extracted human molar teeth were randomly divided into six groups (n= 10); Group I: two-step etch and rinse adhesive system, Adper Single Bond 2 (SB₂) (experimental control), Group II: 2.5% Chitosan+etch+SB₂, Group III: 15% Neem (<i>Azadirachta indica</i>)+etch+SB₂, Group IV: 15% Tulsi (<i>Ocimum sanctum</i>)+etch+SB₂, Group V: 2% Aloe vera+etch+SB₂, and group VI: 2% Chlorhexidine (CHX)+etch+SB₂. Resin composite (Z350, 3M ESPE USA) was placed over the prepared dentin surfaces and was light cured. Data analysis was performed using One-way ANOVA and post hoc Tukey's test (<i>p</i>< 0.05).</p><p><strong>Results: </strong>Neem specimens showed the highest mean SBS, statistically greater than the control (<i>p</i>= 0.042). Other experimental groups showed no significant differences in SBS comparison to the control. The mean SBS values of 2.5% Chitosan, 15% Neem, 15% Tulsi, and 2% Aloe vera were significantly higher than 2% CHX (<i>p</i>= 0.046, <i>p</i>= 0.001, <i>p</i>= 0.010 and <i>p</i>= 0.002 respectively).</p><p><strong>Conclusion: </strong>Dentin pretreatment with Neem may improve the bond strength of a two-step etch and rinse adhesive system. The application of Chitosan, Tulsi, Aloe vera, and CHX did not demonstrate significantly different SBS values from that of the Control, although CHX was lower.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 4","pages":"334-341"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}