ISRN cardiology最新文献_第4页

Intracoronary adenosine versus intravenous adenosine during primary PCI for ST-elevation myocardial infarction: which one offers better outcomes in terms of microvascular obstruction? 在st段抬高型心肌梗死的初次PCI治疗中，冠状动脉内腺苷与静脉内腺苷:哪一种治疗微血管阻塞的效果更好?

ISRN cardiology Pub Date : 2013-03-27 Print Date: 2013-01-01 DOI: 10.1155/2013/248476

Gemina Doolub, Erica Dall'armellina

{"title":"Intracoronary adenosine versus intravenous adenosine during primary PCI for ST-elevation myocardial infarction: which one offers better outcomes in terms of microvascular obstruction?","authors":"Gemina Doolub, Erica Dall'armellina","doi":"10.1155/2013/248476","DOIUrl":"https://doi.org/10.1155/2013/248476","url":null,"abstract":"Aims. Previous studies have suggested that intravenous administration of adenosine improves myocardial reperfusion and reduces infarct size in ST-elevation myocardial infarction (STEMI) patients. Intracoronary administration of adenosine has shown conflicting results. Methods. In this retrospective, single-centre, blinded clinical study, we assessed whether selective intracoronary administration of adenosine distal to the occlusion site immediately before initial balloon inflation reduces microvascular obstruction (MVO) as assessed with cardiac magnetic resonance imaging (MRI). Using contrast-enhanced sequences, microvascular obstruction (MVO) was calculated. We found 81 patients presenting with STEMI within 12 h from symptom onset who were eligible for the study. In 80/81 (100%) patients receiving the study drug, MRI was performed on Day 1 after primary angioplasty. Results. The prevalence of MVO was reduced in the patients treated with intracoronary adenosine, (45%) compared to 85% of patients who were administered intravenous adenosine (P = 0.0043). We found that the size of MVO in patients receiving intracoronary adenosine was significantly reduced compared to 0.91 g in the intravenous-treated group (P = 0.027). There was no statistically significant difference in TIMI flow and clinical outcomes after primary PCI. Conclusion. We found significant evidence that selective high-dose intracoronary administration of adenosine distal to the occlusion site of the culprit lesion in STEMI patients results in a decrease in microvascular obstruction.","PeriodicalId":73519,"journal":{"name":"ISRN cardiology","volume":"2013 ","pages":"248476"},"PeriodicalIF":0.0,"publicationDate":"2013-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31376566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

QRS Complex Enlargement as a Predictor of Ventricular Arrhythmias in Patients Affected by Surgically Treated Tetralogy of Fallot: A Comprehensive Literature Review and Historical Overview. QRS复合体增大作为手术治疗法洛四联症患者室性心律失常的预测因子:综合文献回顾和历史回顾。

ISRN cardiology Pub Date : 2013-01-01 Epub Date: 2013-02-20 DOI: 10.1155/2013/782508

Pier Paolo Bassareo, Giuseppe Mercuro

引用次数: 19

Diagnosis and treatment of asymptomatic left ventricular systolic dysfunction after myocardial infarction. 心肌梗死后无症状左室收缩功能障碍的诊断与治疗。

ISRN cardiology Pub Date : 2013-01-01 Epub Date: 2013-03-12 DOI: 10.1155/2013/731285

Laura Ajello, Giuseppe Coppola, Egle Corrado, Eluisa La Franca, Antonino Rotolo, Pasquale Assennato

引用次数: 8

Pathobiology of obstructive sleep apnea-related dyslipidemia: focus on the liver. 阻塞性睡眠呼吸暂停相关血脂异常的病理生物学:以肝脏为重点。

ISRN cardiology Pub Date : 2013-01-01 Epub Date: 2013-01-02 DOI: 10.1155/2013/687069

Aibek E Mirrakhimov, Alaa M Ali

引用次数: 17

Amiodarone-induced cirrhosis of liver: what predicts mortality? 胺碘酮诱导的肝硬化:什么预测死亡率?

ISRN cardiology Pub Date : 2013-01-01 Epub Date: 2013-03-14 DOI: 10.1155/2013/617943

Nasir Hussain, Anirban Bhattacharyya, Suartcha Prueksaritanond

{"title":"Amiodarone-induced cirrhosis of liver: what predicts mortality?","authors":"Nasir Hussain, Anirban Bhattacharyya, Suartcha Prueksaritanond","doi":"10.1155/2013/617943","DOIUrl":"https://doi.org/10.1155/2013/617943","url":null,"abstract":"Introduction. Amiodarone has been used for more than 5 decades for the treatment of various tachyarrhythmias and previously for the treatment of refractory angina. There are multiple well-established side effects of amiodarone. However, amiodarone-induced cirrhosis (AIC) of liver is an underrecognized complication. Methods. A systematic search of Medline from January 1970 to November 2012 by using the following terms, amiodarone and cirrhosis, identified 37 reported cases of which 30 were used in this analysis. Patients were divided into 2 subsets, survivors versus nonsurvivors, at 5 months. Results. Aspartate aminotransferase was significantly lower (P = 0.03) in patients who survived at 5-months (mean 103.33 IU/L) compared to nonsurvivors (mean 216.88 IU/L). There was no statistical difference in the levels of prothrombin time, total bilirubin, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transpeptidase, cumulative dose, and latency period between the two groups. The prevalence of DM, HTN, HLD, CAD, and CHF was similar in the two groups. None of the above-mentioned variables could be identified as a predictor of survival at 5 months. Conclusion. AIC carries a mortality risk of 60% at 5 months once the diagnosis is established. Further prospective studies are needed to identify predictors of AIC and of mortality or survival in cases of AIC.","PeriodicalId":73519,"journal":{"name":"ISRN cardiology","volume":"2013 ","pages":"617943"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/617943","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31351283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 31

Clinical evaluation of a mobile heart rhythm telemonitoring system. 一种移动式心律远程监测系统的临床评价。

ISRN cardiology Pub Date : 2012-01-01 DOI: 10.5402/2012/192670

Hristo Mateev, Iana Simova, Tzvetana Katova, Nikolay Dimitrov

{"title":"Clinical evaluation of a mobile heart rhythm telemonitoring system.","authors":"Hristo Mateev, Iana Simova, Tzvetana Katova, Nikolay Dimitrov","doi":"10.5402/2012/192670","DOIUrl":"https://doi.org/10.5402/2012/192670","url":null,"abstract":"Purpose. To evaluate the clinical applicability of a telemonitoring system: telemetric system for collection and distant surveillance of medical information (TEMEO). Methods. We evaluated 60 patients, applying simultaneously standard Holter ECG and telemonitoring. Two different comparisons were performed: (1) TEMEO ECG with standard 12-lead ECG; (2) TEMEO Holter with standard ECG Holter. Results. We found a very high coincidence rate (99.3%) between TEMEO derived ECGs and standard ECGs. Intraclass correlation coefficient analysis revealed high and significant correlation coefficients regarding average, maximal, and minimal heart rate, % of time in tachycardia, single supraventricular ectopic beats (SVEB), and single and couplets of ventricular ectopic beats (VEB) between Holter ECG and TEMEO derived parameters. Couplets of SVEB were recorded as different by the two monitoring systems, however, with a borderline statistical significance. Conclusions. TEMEO derived ECGs have a very high coincidence rate with standard ECGs. TEMEO patient monitoring provides results that are similar to those derived from a standard Holter ECG.","PeriodicalId":73519,"journal":{"name":"ISRN cardiology","volume":"2012 ","pages":"192670"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/192670","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9380958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Primary prevention of heart failure. 心力衰竭的初级预防。

ISRN cardiology Pub Date : 2012-01-01 DOI: 10.5402/2012/982417

Javed Butler

引用次数: 28

Primary cardiac tumours: a single-center 41-year experience. 原发性心脏肿瘤:单中心41年的经验。

ISRN cardiology Pub Date : 2012-01-01 Epub Date: 2012-06-27 DOI: 10.5402/2012/906109

Christina Maria Steger, Thomas Hager, Elfriede Ruttmann

引用次数: 47

High-Bandpass Filters in Electrocardiography: Source of Error in the Interpretation of the ST Segment. 心电图中的高带通滤波器:ST段解释的误差来源。

ISRN cardiology Pub Date : 2012-01-01 Epub Date: 2012-06-21 DOI: 10.5402/2012/706217

F Buendía-Fuentes, M A Arnau-Vives, A Arnau-Vives, Y Jiménez-Jiménez, J Rueda-Soriano, E Zorio-Grima, A Osa-Sáez, L V Martínez-Dolz, L Almenar-Bonet, M A Palencia-Pérez

{"title":"High-Bandpass Filters in Electrocardiography: Source of Error in the Interpretation of the ST Segment.","authors":"F Buendía-Fuentes, M A Arnau-Vives, A Arnau-Vives, Y Jiménez-Jiménez, J Rueda-Soriano, E Zorio-Grima, A Osa-Sáez, L V Martínez-Dolz, L Almenar-Bonet, M A Palencia-Pérez","doi":"10.5402/2012/706217","DOIUrl":"https://doi.org/10.5402/2012/706217","url":null,"abstract":"Introduction. Artifactual variations in the ST segment may lead to confusion with acute coronary syndromes. Objective. To evaluate how the technical characteristics of the recording mode may distort the ST segment. Material and Method. We made a series of electrocardiograms using different filter configurations in 45 asymptomatic patients. A spectral analysis of the electrocardiograms was made by discrete Fourier transforms, and an accurate recomposition of the ECG signal was obtained from the addition of successive harmonics. Digital high-pass filters of 0.05 and 0.5 Hz were used, and the resulting shapes were compared with the originals. Results. In 42 patients (93%) clinically significant alterations in ST segment level were detected. These changes were only seen in \"real time mode\" with high-pass filter of 0.5 Hz. Conclusions. Interpretation of the ST segment in \"real time mode\" should only be carried out using high-pass filters of 0.05 Hz.","PeriodicalId":73519,"journal":{"name":"ISRN cardiology","volume":" ","pages":"706217"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/706217","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30750404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 56

Computational cardiology: the heart of the matter. 计算心脏病学:问题的核心。

ISRN cardiology Pub Date : 2012-01-01 DOI: 10.5402/2012/269680

Natalia A Trayanova

引用次数: 31