ISRN cardiology最新文献_第10页

Comparison of 12-month outcomes with zotarolimus- and Paclitaxel-eluting stents: a meta-analysis. 佐他莫司和紫杉醇洗脱支架12个月疗效比较:荟萃分析

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-05-26 DOI: 10.5402/2011/675638

Rohit S Loomba, Suraj Chandrasekar, Neil Malhotra, Rohit R Arora

{"title":"Comparison of 12-month outcomes with zotarolimus- and Paclitaxel-eluting stents: a meta-analysis.","authors":"Rohit S Loomba, Suraj Chandrasekar, Neil Malhotra, Rohit R Arora","doi":"10.5402/2011/675638","DOIUrl":"https://doi.org/10.5402/2011/675638","url":null,"abstract":"Revascularization after myocardial infarction is often achieved via percutaneous coronary intervention, which often entails stenting. Drug-eluting stents have shown benefits over bare metal stents in this setting, and a variety of drug-eluting stents are now available, including sirolimus-, paclitaxel-, and zotarolimus-eluting stents. There are studies that have compared the various drug-eluting stents and this meta-analysis pools data comparing 12-month clinical outcomes of zotarolimus- and paclitaxel-eluting stents. End points studied were myocardial infarction, major adverse cardiac events, cardiac death, all-cause death, stent thrombosis, target vessel revascularization, and target lesion revascularization.There was a statistically significant reduction in risk of myocardial infarction (odds ratio, 0.250, confidence interval, 0.160 to 0.392) and statistically insignificant reductions in major adverse cardiac events (odds ratio, 0.813, confidence interval, 0.656 to 1.007), cardiac death (odds ratio, 0.817, confidence interval, 0.359 to 1.857), all cause death (odds ratio, 0.820, confidence interval, 0.443 to 1.516), and target lesion revascularization (odds ratio, 0.936, confidence interval 0.702 to 1.247). There was a statistically significant increase in target vessel revascularization (odds ratio, 1.336, confidence interval, 1.003 to 1.778) and a statistically insignificant increase in stent thrombosis (odds ratio, 1.174, confidence interval, 0.604 to 2.280). These findings are similar to the individual studies although other studies have noted increased late loss with zotarolimus-eluting stents and this current data associated with late loss should be kept in mind when makimg clinical decisions regarding sent selection.","PeriodicalId":73519,"journal":{"name":"ISRN cardiology","volume":"2011 ","pages":"675638"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30470822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of PPARα Intron 7 Polymorphism with Coronary Artery Disease: A Cross-Sectional Study. PPARα内含子7多态性与冠状动脉疾病的相关性:一项横断面研究

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-04-07 DOI: 10.5402/2011/816025

Sreeja Purushothaman, V K Ajitkumar, R Renuka Nair

引用次数: 11

Estimation of absolute cardiovascular risk in individuals with diabetes mellitus: rationale and approaches. 估计糖尿病患者的绝对心血管风险:基本原理和方法。

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-11-23 DOI: 10.5402/2011/242656

Justin B Echouffo-Tcheugui, Modele O Ogunniyi, André P Kengne

{"title":"Estimation of absolute cardiovascular risk in individuals with diabetes mellitus: rationale and approaches.","authors":"Justin B Echouffo-Tcheugui, Modele O Ogunniyi, André P Kengne","doi":"10.5402/2011/242656","DOIUrl":"https://doi.org/10.5402/2011/242656","url":null,"abstract":"Purpose. To examine the usefulness of cardiovascular risk estimation models in people with diabetes. Methods. Review of published studies that compare the discriminative power of major cardiovascular risk factors single or in combination in individuals with and without diabetes, for major cardiovascular outcomes. Results. In individuals with and without diabetes, major risk factors affect cardiovascular risk similarly, with no evidence of any significant interaction. Accounting for diabetes-specific parameters, cardiopreventative therapies can significantly improve risk estimation in diabetes. General and diabetes-specific cardiovascular risk models have a useful discriminative power, but tend to overestimate risk in individuals with diabetes. Their impact on care delivery, adherence to therapies, and patients' outcome remain poorly understood. Conclusions. The high-risk status conferred by diabetes does not preclude the estimation of absolute cardiovascular risk estimation using global risk tools in individuals with diabetes, as this is useful for the initiation and intensification of preventive measures.","PeriodicalId":73519,"journal":{"name":"ISRN cardiology","volume":"2011 ","pages":"242656"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30472046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Genetic Polymorphisms as Risk Stratification Tool in Primary Preventive ICD Therapy. 遗传多态性作为初级预防ICD治疗的风险分层工具。

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-04-18 DOI: 10.5402/2011/457247

Roman Laszlo, Mathias C Busch, Jüergen Schreieck

引用次数: 1

Surgical treatment in active infective endocarditis: results of a four-year experience. 活动性感染性心内膜炎的手术治疗:四年经验的结果。

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-05-18 DOI: 10.5402/2011/492543

Carlo Rostagno, Enrico Carone, Alessandra Rossi, Gian Franco Gensini, Pier Luigi Stefano

引用次数: 9

Coronary artery perforation and regrowth of a side branch occluded by a polytetrafluoroethylene-covered stent implantation. 冠状动脉穿孔和侧支再生闭塞聚四氟乙烯支架植入。

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-04-26 DOI: 10.5402/2011/212851

Shams Y-Hassan, Christer Sylvén, Loghman Henareh

引用次数: 0

Relationship between Younger Age, Autoimmunity, Cardiometabolic Risk, Oxidative Stress, HAART, and Ischemic Stroke in Africans with HIV/AIDS. 非洲艾滋病毒/艾滋病患者的年龄、自身免疫、心脏代谢风险、氧化应激、HAART 和缺血性中风之间的关系。

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-05-23 DOI: 10.5402/2011/897908

Benjamin Longo-Mbenza, Murielle Longokolo Mashi, Michel Lelo Tshikwela, Etienne Mokondjimobe, Thierry Gombet, Bertrand Ellenga-Mbolla, Augustin Nge Okwe, Nelly Kangola Kabangu, Simon Mbungu Fuele

{"title":"Relationship between Younger Age, Autoimmunity, Cardiometabolic Risk, Oxidative Stress, HAART, and Ischemic Stroke in Africans with HIV/AIDS.","authors":"Benjamin Longo-Mbenza, Murielle Longokolo Mashi, Michel Lelo Tshikwela, Etienne Mokondjimobe, Thierry Gombet, Bertrand Ellenga-Mbolla, Augustin Nge Okwe, Nelly Kangola Kabangu, Simon Mbungu Fuele","doi":"10.5402/2011/897908","DOIUrl":"10.5402/2011/897908","url":null,"abstract":"Background and Purpose. It now appears clear that both HIV/AIDS and antiretroviral therapy (HAART) use are associated with higher risk of cardiovascular disease such as stroke. In this study, we evaluated the prevalence, the risk factors, and the cardiometabolic comorbidities of stroke in HIV/AIDS Central African patients. Methods. This hospital-based cross-sectional study collected clinical, laboratory, and imaging data of black Central African heterosexual, intravenous drug nonuser, and HIV/AIDS patients. Results. There were 54 men and 62 women, with a female to male ratio of 1.2 : 1. All were defined by hypercoagulability and oxidative stress. Hemorrhagic stroke was reported in 1 patient, ischemic stroke in 17 patients, and all stroke subtypes in 18 patients (15%). Younger age <45 years (P = .003), autoimmunity (P < .0001), and metabolic syndrome defined by IDF criteria (P < .0001) were associated with ischemic stroke. Conclusions. Clustering of several cardiometabolic factors, autoimmunity, oxidative stress, and lifestyle changes may explain accelerated atherosclerosis and high risk of stroke in these young black Africans with HIV/AIDS. Prevention and intervention programs are needed.","PeriodicalId":73519,"journal":{"name":"ISRN cardiology","volume":"2011 ","pages":"897908"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30471291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of some common food constituents on cardiovascular disease. 一些常见食物成分对心血管疾病的影响。

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-06-16 DOI: 10.5402/2011/397136

Yaling Yang, Sze Wa Chan, Miao Hu, Richard Walden, Brian Tomlinson

引用次数: 35

Short-term effects of ketamine and isoflurane on left ventricular ejection fraction in an experimental Swine model. 氯胺酮和异氟醚对实验性猪左心室射血分数的短期影响。

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-06-27 DOI: 10.5402/2011/582658

Benjamin Wessler, Christopher Madias, Natesa Pandian, Mark S Link

{"title":"Short-term effects of ketamine and isoflurane on left ventricular ejection fraction in an experimental Swine model.","authors":"Benjamin Wessler, Christopher Madias, Natesa Pandian, Mark S Link","doi":"10.5402/2011/582658","DOIUrl":"https://doi.org/10.5402/2011/582658","url":null,"abstract":"Background. General anesthesia is an essential element of experimental medical procedures. Ketamine and isoflurane are agents commonly used to induce and maintain anesthesia in animals. The cardiovascular effects of these anesthetic agents are diverse, and the response of global myocardial function is unknown. Methods. In a series of 15 swine, echocardiography measurements of left ventricular ejection fraction (LVEF) were obtained before the animals received anesthesia (baseline), after an intramuscular injection of ketamine (postketamine) and after inhaled isoflurane (postisoflurane). Results. The mean LVEF of an unanesthetized swine was 47 ± 3%. There was a significant decrease in the mean LVEF after administration of ketamine to 41 + 6.5% (P = 0.003). The addition of inhaled isoflurane did not result in further decrease in mean LVEF (mean LVEF 38 ± 7.2%, P = 0.22). Eight of the swine had an increase in their LVEF with sympathetic stimulation. Conclusions. In our experimental model the administration of ketamine was associated with decreased LV function. The decrease may be largely secondary to a blunting of sympathetic tone. The addition of isoflurane to ketamine did not significantly change LV function. A significant number of animals had returned to preanesthesia LV function with sympathetic stimulation.","PeriodicalId":73519,"journal":{"name":"ISRN cardiology","volume":"2011 ","pages":"582658"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2011/582658","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30470818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Survival after drowning with cardiac arrest and mild hypothermia. 溺水后心脏骤停和轻度体温过低的存活。

ISRN cardiology Pub Date : 2011-01-01 Epub Date: 2011-04-26 DOI: 10.5402/2011/895625

S S Rudolph, S Barnung

引用次数: 8