Iranian journal of cancer prevention最新文献

{"title":"Evaluation of the Prevalence Rate and the Prognostic Effect of Human Papilloma Virus Infection in a Group of Patients With Oral Cavity Squamous Cell Carcinoma","authors":"N. Saghravanian, M. Zamanzadeh, Z. Meshkat, M. Afzal Aghaee, R. Salek","doi":"10.17795/ijcp-3998","DOIUrl":"https://doi.org/10.17795/ijcp-3998","url":null,"abstract":"Background Squamous cell carcinoma (SCC) is the most common malignancy of the oral cavity. A relationship between the human papilloma virus (HPV) infection and the prognosis of oral cavity SCC (OCSCC) has been discussed before. Objectives We investigated the prevalence rate of HPV status in patients with OCSCC, and its effects on clinicopathological characteristics of tumors and patients’ prognosis. Patients and Methods Sections of formalin-fixed, paraffin-embedded tissue blocks from 114 histopathologically confirmed OCSCC cases were investigated in this study. Polymerase chain reaction (PCR) was applied to evaluate the HPV status in the samples. Results Fifteen (13.16%) cases were identified as HPV positive. The detected viral subtypes in this study were the subtypes 6 and 11. The stage and especially lymph node stage was significantly higher in the HPV positive group compared to the HPV negative group (P = 0.04). Disease free survival (DFS) was remarkably lower in the HPV positive group compared to the HPV negative group (13.9 vs. 49.9 months, P = 0.02). Overall survival (OS) was also significantly inferior in the HPV positive group (15.7 vs. 49.6 months, P = 0.01). In the current study, no significant differences were observed between two groups in relation to the variables of age, gender, tumors site, tumor size, tumor grading and also the recurrence rate. Conclusions The observed higher mortality rate among the HPV positive group indicates the poorer prognosis of this group in comparison with the HPV negative patients. The incidence rate of HPV infection was low in the studied samples; however, interaction of subtypes 6 and 11 of HPV in poorer prognosis of the patients and a carcinogenic role of HPV in OCSCC cannot be ruled out.","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68178783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Complete Decongestive Therapy on Edema Volume Reduction and Pain in Women With Post Breast Surgery Lymph Edema.","authors":"Leila Angooti Oshnari, Seyed Ali Hosseini, Shahpar Haghighat, Samaneh Hossein Zadeh","doi":"10.17795/ijcp-4209","DOIUrl":"10.17795/ijcp-4209","url":null,"abstract":"<p><strong>Background: </strong>Upper extremity lymph edema is the most common side effect of breast cancer treatment that may produce significant physical and psychological morbidity. Pain is the frequent symptom of lymph edema that causes impairment of activities in daily life.</p><p><strong>Objectives: </strong>The aim of this study was assessment of the effect of complex decongestive therapy (CDT) on upper extremity lymph edema and pain in women with post breast surgery lymph edema.</p><p><strong>Patients and methods: </strong>In this quasi- experimental research with before- after design, 36 women with moderate lymph edema after breast surgery participated in the program. Edema volume was measured by water displacement method; pain values were evaluated by visual analog scale (VAS). Data were recorded before intervention and 2 and 4 weeks after it. CDT included the first phase (intensive phase) and the second phase (maintenance phase). Each phase lasted 2 weeks. After use of Shapiro Wilk test for normality, analysis of variances with GEE and repeated measurements were used to analyze the data.</p><p><strong>Results: </strong>After one month doing CDT program, significant decrease of edema was noticed (P < 0.0001), also pain decreased during 2 and 4 weeks after intervention (P < 0.0001).</p><p><strong>Conclusions: </strong>This study indicated that CDT program is effective in reducing lymph edema volume and pain in women with moderate post breast surgery lymph edema. It seems that raising patients' awareness and training healthcare professionals regarding lymph edema preventive strategies have an important role in earlier and better combating this complication.</p>","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/80/ijcp-09-02-4209.PMC4951770.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34626956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating Levels of M30 and M65 Molecules in Transitional Cell Carcinoma of the Bladder and Their Relation to Tumor Progression.","authors":"Zahra Malek-Hosseini,&nbsp;Abdolaziz Khezri,&nbsp;Zahra Amirghofran","doi":"10.17795/ijcp-4086","DOIUrl":"https://doi.org/10.17795/ijcp-4086","url":null,"abstract":"<p><strong>Background: </strong>Various markers are suggested for diagnosis and monitoring of transitional cell carcinoma of the bladder (TCC), including cytokeratins (CKs).</p><p><strong>Objectives: </strong>In the present study, the circulating CK18 (M65) and its caspase-cleaved form, ccCK18 (M30), have been investigated in a group of patients with TCC.</p><p><strong>Patients and methods: </strong>Serum samples were obtained from 60 patients before surgical resection, among which the samples of 26 patients after resection were also included. We measured the levels of soluble M30 and M65 molecules by enzyme-linked immunosorbent assay. The relation between these markers and patients' clinical characteristics was evaluated.</p><p><strong>Results: </strong>M30 and M65 in total patient sera were 148 ± 16 U/L and 318 ± 34 U/L, respectively. A correlation existed between pre-operative M30 and M65 levels (P < 0.0001, Spearman r = 0.51). M65, but not M30, showed a significant relation to tumor stage and grade. The M65 quantity in patients with T3/T4 tumor stages (350 ± 42 U/L) was higher than that of patients with T1/T2 stages (293 ± 45U/L; P < 0.038). Patients with tumor grades III/IV also showed higher levels of M65 compared to patients with tumor grades I/II (P < 0.04). The M30:M65 ratio in all patients was 0.54 ± 0.04. There was a lower M30:M65 ratio in patients with T3/T4 stage tumors and those with tumor grades III/IV (P < 0.02). The M30 (133 ± 19 U/L) and M65 levels (240 ± 21 U/L) after surgery did not significantly differ compared to their pre-operative values. However, a correlation between the pre- and post-operative M30:M65 ratio in patients ≥ 70 years was seen (P = 0.009).</p><p><strong>Conclusions: </strong>These data suggested a relationship of both M65 and the M30:M65 ratio to tumor progression which might imply their importance in TCC monitoring.</p>","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/61/ijcp-09-02-4086.PMC4951759.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34626955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Correlation of Plasma 25-Hydroxyvitamin D Deficiency With Risk of Breast Neoplasms: A Systematic Review","authors":"Reza Shekarriz-Foumani, Faezeh Khodaie","doi":"10.17795/ijcp-4469","DOIUrl":"https://doi.org/10.17795/ijcp-4469","url":null,"abstract":"Context Breast cancer has been considered as one of the most common types of cancer among the women worldwide, and patients with breast neoplasms have been reported with high prevalence of low serum 25-hydroxyvitamin D levels. Objectives Our aim was to evaluate the correlation of plasma 25-hydroxyvitamin D deficiency with breast neoplasms risk among women. Data Sources PubMed database was searched with MeSH (medical subject headings) keywords \"vitamin D AND breast neoplasms\" which was restricted by original articles written only in English and published from January 1, 2014. Study Selection To find the articles that met eligibility criteria, titles and abstracts were examined. Data Extraction This systematic review was conducted according to PRISMA (preferred reporting items for systematic reviews and meta-analyses) statement. Critical appraising of evidence was performed, using the study quality assessment tools of national institutes of health, national heart, lung and blood institute (NHLBI). Results Overall, 76 potential articles were identified and after screening, 13 articles met eligible criteria for inclusion. Definition of low vitamin D levels varied greatly among studies, making comparisons difficult, but most of them have defined deficiency as 25(OH)D < 20 ng/mL. Evidence was mainly of fair quality. Conclusions This study has provided evidence that vitamin D deficiency has been very prevalent in patients with breast neoplasms, more than comparable matched control population, and risk of breast cancer has increased with low vitamin D levels, suggesting the need for high quality studies that assessed the health consequences attributable to vitamin D deficiency employing standard definitions.","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68181172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing a WebGIS for Geo-Visualization of Cancer.","authors":"Mostafa Khoshabi, Mohammad Taleai, Ali Motlagh, Farnaz Hosseini Kamal","doi":"10.17795/ijcp-3910","DOIUrl":"10.17795/ijcp-3910","url":null,"abstract":"<p><strong>Background: </strong>Considering the hygiene facilities and sharing the data of diseases, considerable attempts to promote the public awareness have been made by various media; however, most of the provided information is based on numerical and verbal statistics, and may not provide suitable understanding for people in regard with the situation of diseases.</p><p><strong>Objectives: </strong>The main aim of this study is to design an interactive WebGIS system in which people could simply produce and observe their favorite maps of different cancers and environmental parameters. They can use this tools to produce their personalized maps and explore various aspects of the cancer.</p><p><strong>Materials and methods: </strong>A system has been developed by using WebGIS for convenience of ordinary users without any knowledge about geospatial information system (GIS) to observe the situation of the diseases and environmental conditions in terms of static and user-produced interactive maps. It has also provided the possibility of spatial comparison of the arbitrary parameters in the framework of bar and pie diagrams. This system has been designed and launched on cancer database of Iran where information of meteorological stations has been embedded as environmental parameters.</p><p><strong>Results: </strong>The innovative idea in this study has received less attention in previous works including possibility of producing web-based Choropleth map so that users could easily select the parameters and algorithms for classification and interactive coloring in the system to produce their personalized maps.</p><p><strong>Conclusions: </strong>Development of WebGIS tools and increased cooperation of people in terms of inserting the spatial labels on the map to report a disease or using their views about reasons of occurring a specific cancer in a specific region may cause turning the process of mono-direction flow of information to users to a bi-directional flow of information. As a result, cancer specialists could use the knowledge of local people and residents of different regions of the country to better analyze the situation of various kinds of cancers.</p>","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f1/72/ijcp-09-02-3910.PMC4951768.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34626953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Socioeconomic Status and Participation in Colonoscopy Screening Program in First Degree Relatives of Colorectal Cancer Patients.","authors":"Arezoo Chouhdari, Parvin Yavari, Mohammad Amin Pourhoseingholi, Mohammad-Reza Sohrabi","doi":"10.17795/ijcp-4809","DOIUrl":"10.17795/ijcp-4809","url":null,"abstract":"<p><strong>Background: </strong>Approximately 15% to 25% of colorectal cancer (CRC) cases have positive family history for disease. Colonoscopy screening test is the best way for prevention and early diagnosis. Studies have found that first degree relatives (FDRs) with low socioeconomic status are less likely to participate in colonoscopy screening program.</p><p><strong>Objectives: </strong>The aim of this study is to determine the association between socioeconomic status and participation in colonoscopy screening program in FDRs.</p><p><strong>Patients and methods: </strong>This descriptive cross-sectional, study has been conducted on 200 FDRs who were consulted for undergoing colonoscopy screening program between 2007 and 2013 in research institute for gastroenterology and liver disease of Shahid Beheshti University of Medical Sciences, Tehran, Iran. They were interviewed via phone by a valid questionnaire about socioeconomic status. For data analysis, chi-square, exact fisher and multiple logistic regression were executed by SPSS 19.</p><p><strong>Results: </strong>The results indicated 58.5% participants underwent colonoscopy screening test at least once to the time of the interview. There was not an association between participation in colonoscopy screening program and socioeconomic status to the time of the interview in binomial analysis. But statistical significance between intention to participate and educational and income level were found. We found, in logistic regression analysis, that high educational level (Diploma and University degree in this survey) was a predictor to participate in colonoscopy screening program in FDRs.</p><p><strong>Conclusions: </strong>According to this survey low socioeconomic status is an important factor to hinder participation of FDRs in colonoscopy screening program. Therefore, planned interventions for elevation knowledge and attitude in FDRs with low educational level are necessary. Also, reducing colonoscopy test costs should be a major priority for policy makers.</p>","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c7/28/ijcp-09-02-4809.PMC4951766.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34334525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal Presentation of Choriocarcinoma and Literature Review.","authors":"Zohreh Yousefi,&nbsp;Mansorhe Mottaghi,&nbsp;Alireza Rezaei,&nbsp;Sedighe Ghasemian","doi":"10.17795/ijcp-4389","DOIUrl":"https://doi.org/10.17795/ijcp-4389","url":null,"abstract":"<p><strong>Introduction: </strong>Gestational trophoblastic neoplasms have highly been malignant potential, which usually occurred in child-bearing age women. Unusual feature of this malignancy would be rare, it was important to take in mind the possibility of GTN in different manifestation. Based on the above mentioned, the aim of this presentation would be the management and outcome of a case series of choriocarcinoma patients with abnormal manifestation.</p><p><strong>Case presentation: </strong>We have presented four patients, first who initially manifestation with signs of septic shock, the second case with severe gastrointestinal hemorrhage, the third case with postpartum infection and the forth case was a postmenopausal bleeding patient.</p><p><strong>Conclusions: </strong>In case of metastatic choriocarcinoma with precise history, accurate diagnosis and appropriate treatment have led us to curable results.</p>","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.17795/ijcp-4389","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34626958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanocarriers Usage for Drug Delivery in Cancer Therapy.","authors":"Hadi Khodabandehloo,&nbsp;Hamid Zahednasab,&nbsp;Asghar Ashrafi Hafez","doi":"10.17795/ijcp-3966","DOIUrl":"https://doi.org/10.17795/ijcp-3966","url":null,"abstract":"<p><p>Conventional therapeutic agents have displayed significant shortcomings. For this reason, important achievements have effectively made in biotechnology for delivering the therapeutic agents to the site of action, and diminish side effects. Polymeric carriers, micelles, dendrimers, liposomes, solid lipid carriers, gold carriers, viral carriers, nanotubes and magnetic carriers incorporating cytotoxic therapeutics have developed. To improve biological distribution of therapeutic drugs, some modified carriers have designed in optimal size and modified surface area. Delivery of carriers to target cells could be done by passive and active targeting. </p>","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.17795/ijcp-3966","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34626954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postmenopausal Breast Cancer Risk in Relation to Antibodies Specific to Benzo[a]Pyrene, Estradiol and Progesterone.","authors":"Andrew Glushkov,&nbsp;Elena Polenok,&nbsp;Mikhail Kostyanko,&nbsp;Alexandr Antonov,&nbsp;Natalia Verzhbitskaya,&nbsp;Ilgiz Vafin,&nbsp;Svetlana Ragozhina","doi":"10.17795/ijcp-4212","DOIUrl":"https://doi.org/10.17795/ijcp-4212","url":null,"abstract":"<p><strong>Background: </strong>Antibodies might protect against low doses of environmental carcinogens by decreasing systemic uptake, activation of metabolic pathways, and redistribution of carcinogens within the organism. The features of antibody formation in relation to environmental carcinogens and sex steroids under natural conditions should be determined to identify breast cancer risk, then to develop cancer immune prevention strategies.</p><p><strong>Objectives: </strong>The purpose of this study was to investigate antibodies specifications to benzo(a)pyrene, estradiol and progesterone in postmenopausal women with invasive breast cancer.</p><p><strong>Patients and methods: </strong>A semi-quantitative non-competitive immunoassay of IgG antibodies to benzo(a)pyrene (IgG-Bp), estradiol (IgG-Es), and progesterone (IgG-Pg) has conducted. The assay has performed on 322 serum samples from patients with breast cancer and 179 serum samples from healthy postmenopausal women by using low-molecular-weight Bp, Es, and Pg conjugated with bovine serum albumin. ROC analysis has also conducted to determine the odds ratio (OR).</p><p><strong>Results: </strong>Combination of the high levels of IgG-Bp and IgG-Es without IpG-Pg was more frequent in breast cancer patients than that in healthy women, and the OR has increased to 3.8. Combination of the high levels of IgG-Pg with high levels of both IgG-Bp and IgG-Es were significantly more frequent in breast cancer patients (36.9%) than that in healthy women (5.6%), and the OR increased to 11.7. These differences have peculiarly expressed in breast cancer patients with hormone status ER+/PR- (OR = 26.7). The minimum OR (0.4) has obtained at low levels of the three antibodies.</p><p><strong>Conclusions: </strong>Immunoassay of antibodies against environmental carcinogens and sex steroid hormones could use to detect breast cancer risk. Induction of antibodies against Bp for cancer immunoprevention could lead to antibody formation against steroid hormones, thereby increasing breast cancer risk.</p>","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/1f/ijcp-09-02-4212.PMC4951760.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34626957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iranian Nurses Perceptions of Cancer Patients Quality of Life","authors":"M. Bahrami","doi":"10.17795/ijcp-4076","DOIUrl":"https://doi.org/10.17795/ijcp-4076","url":null,"abstract":"Background Cancer is the third main cause of death in Iran only after cardiovascular diseases and accidents. Objectives The main aim of this research study was to identify nurses’ understanding of cancer patients’ Quality of Life (QoL) in an Iranian context. Patients and Methods This descriptive correlational study was conducted in an educative referral oncology center affiliated to Isfahan University of Medical Sciences, Isfahan, Iran in 2013. 50 pairs of cancer patients and their nurses were conveniently recruited. The sample of nurses were selected based on consensus sampling which included more than 70 percent of eligible nurses in the hospital. Patients and nurses were requested to complete the Farsi version of the world health organization quality of life (WHOQoL-BREF) questionnaire, separately. QoL was measured across four dimensions including physical, psychological, social relationship and environmental. Results The QoL mean domain scores of patients were 10.06, 11.88, 12.76 and 11.96, respectively. The corresponding scores of nurses were 11.6, 11.23, 12.65 and 12.07. Pearson correlations between patients and nurses scores were 0.42, 0.5, 0.25 and 0.58 which revealed a fair to moderate agreement between nurses’ and patients’ scores in different domains. Paired samples t-test values indicated that physical QoL mean domain scores of patients were significantly lower than the corresponding drawings of nurses [t (49) = -3.41, P < 0.001]. Conclusions The main finding of this QoL study was that nurses generally have a moderate understanding of cancer patients’ QoL. Therefore, in order to meet different physio-psycho-social needs of patients, nurses must enhance their understanding of patients’ QoL particularly in more subjective and personal domains like social domain using a holistic approach.","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68179528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}