纳米载体在癌症治疗中的应用。

Iranian journal of cancer prevention Pub Date : 2016-04-24 eCollection Date: 2016-04-01 DOI:10.17795/ijcp-3966
Hadi Khodabandehloo, Hamid Zahednasab, Asghar Ashrafi Hafez
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引用次数: 73

摘要

传统的治疗药物已经显示出明显的缺陷。因此,生物技术在将治疗药物运送到作用部位并减少副作用方面取得了重要成就。聚合载体、胶束、树状大分子、脂质体、固体脂质载体、金载体、病毒载体、纳米管和结合细胞毒性治疗的磁性载体已经发展起来。为了改善治疗药物的生物分布,一些修饰载体被设计成最佳的尺寸和修饰的表面积。载体的递送可通过被动靶向和主动靶向两种方式完成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Nanocarriers Usage for Drug Delivery in Cancer Therapy.

Nanocarriers Usage for Drug Delivery in Cancer Therapy.

Conventional therapeutic agents have displayed significant shortcomings. For this reason, important achievements have effectively made in biotechnology for delivering the therapeutic agents to the site of action, and diminish side effects. Polymeric carriers, micelles, dendrimers, liposomes, solid lipid carriers, gold carriers, viral carriers, nanotubes and magnetic carriers incorporating cytotoxic therapeutics have developed. To improve biological distribution of therapeutic drugs, some modified carriers have designed in optimal size and modified surface area. Delivery of carriers to target cells could be done by passive and active targeting.

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