{"title":"Personal protective equipment and micro-nano plastics: A review of an unavoidable interrelation for a global well-being hazard","authors":"Shaheen Akhtar , Kumar Pranay , Kanchan Kumari","doi":"10.1016/j.heha.2023.100055","DOIUrl":"10.1016/j.heha.2023.100055","url":null,"abstract":"<div><p>The usage and the demand for personal protective equipments (PPEs) for our day-to-day survival in this pandemic period of COVID-19 have seen a steep rise which has consequently led to improper disposal and littering. Fragmentation of these PPE units has eventually given way to micro-nano plastics (MNPs) emission in the various environmental matrices and exposure of living organisms to these MNPs has proven to be severely toxic. Numerous factors contribute to the toxicity imparted by these MNPs that mainly include their shape, size, functional groups and their chemical diversity. Even though multiple studies on the impacts of MNPs toxicity are available for other organisms, human cell line studies for various plastic polymers, other than the most common ones namely polyethylene (PE), polystyrene (PS) and polypropylene (PP), are still at their nascent stage and need to be explored more. In this article, we cover a concise review of the literature on the impact of these MNPs in biotic and human systems focusing on the constituents of the PPE units and the additives that are essentially used for their manufacturing. This review will subsequently identify the need to gather scientific evidence at the smaller level to help combat this microplastic pollution and induce a more in-depth understanding of its adverse effect on our existence.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100055"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9352838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Judy S. LaKind , Carol J. Burns , Giffe T. Johnson , Sabine S. Lange
{"title":"Epidemiology for risk assessment: The US Environmental Protection Agency quality considerations and the Matrix","authors":"Judy S. LaKind , Carol J. Burns , Giffe T. Johnson , Sabine S. Lange","doi":"10.1016/j.heha.2023.100059","DOIUrl":"https://doi.org/10.1016/j.heha.2023.100059","url":null,"abstract":"<div><p>Epidemiology research plays an important role in regulatory risk assessments. However, regulatory approaches to evaluating study utility and quality for risk assessment purposes can vary, even within a single agency. The goal of the current review is to compare different guidelines within the US Environmental Protection Agency (US EPA) for evaluating epidemiology research with respect to quality. This review highlights the elements of epidemiology design and reporting that are most useful for risk assessment and regulatory decision making. General guidance documents from the US EPA that assess pesticides (Office of Pesticide Programs Framework), air pollutants (Integrated Science Assessment Preamble), and environmental chemicals (Integrated Risk Information System Handbook) were included. Chemical-specific examples of the use of these guidance documents were selected to provide additional information on each methodology. All three evaluation approaches require professional judgment, and none include a quantitative scoring approach. All indicate numerous aspects that enhance the value of a study for risk assessment. However, the methods and the level of detail vary. More clarity within US EPA documents would aid researchers. The elements of the Matrix tool, designed to facilitate translation of epidemiology studies to risk assessment, build on the US EPA epidemiology guidelines and may further enhance the value of such studies.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100059"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49899211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peerzada Gh Jeelani , Syed Muzammil Munawar , S. Khaleel Basha , Gopi Krishna P , Bruce Joshua Sinclair , A Dharshini Jenifer , Nupur Ojha , Abdel-Tawab Mossa , Ramalingam Chidambaram
{"title":"Exploring possible strategies for treating SARS-CoV-2 in sewage wastewater: A review of current research and future directions","authors":"Peerzada Gh Jeelani , Syed Muzammil Munawar , S. Khaleel Basha , Gopi Krishna P , Bruce Joshua Sinclair , A Dharshini Jenifer , Nupur Ojha , Abdel-Tawab Mossa , Ramalingam Chidambaram","doi":"10.1016/j.heha.2023.100056","DOIUrl":"10.1016/j.heha.2023.100056","url":null,"abstract":"<div><p>The advent of acute respiratory coronavirus disease (COVID-19) is convoyed by the shedding of the virus in stool. Although inhalation from person-to-person and aerosol/droplet transmission are the main modes of SARS-Coronavirus-2 (SARS-CoV-2) transmission, currently available evidence indicates the presence of viral RNA in the sewerage wastewater, which highlights the need for more effective corona virus treatment options. In the existing COVID-19 pandemic, a substantial percentage of cases shed SARS-CoV-2 viral RNA in their faeces. Hence the treating this sewerage wastewater with proper surveillance is essential to contain this deadly pathogen from further transmission. Since, the viral disinfectants will not be very effective on sewerage waste as organic matter, and suspended solids in water can protect viruses that adsorb to these particles. More effective methods and measures are needed to prevent this virus from spreading. This review will explore some potential methods to treat the SARS-CoV-2 infected sewerage wastewater, current research and future directions.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100056"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9397133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Blood Total Mercury with Dyslipidemia in a sample of U.S. Adolescents: Results from the National Health and Nutrition Examination Survey Database, 2011–2018","authors":"Chibuzor Abasilim, Victoria Persky, Mary E. Turyk","doi":"10.1016/j.heha.2023.100047","DOIUrl":"10.1016/j.heha.2023.100047","url":null,"abstract":"<div><h3>Background</h3><p>Abnormal lipid profiles in adolescents predict metabolic and cardiovascular diseases in adulthood. While seafood consumption is the primary source of mercury exposure, it also provides beneficial nutrients such as omega-3 fatty acids (O3FA). Prior studies indicate that blood total mercury (TBHg) has endocrine disrupting effects and may be associated with abnormal lipid profiles in adolescents. However, the impact of beneficial nutrients on this relationship has not been examined. Our study investigated the relationship of TBHg with dyslipidemia and lipid profiles and potential confounding and modification of these relationships by sex, body mass index (BMI), selenium and O3FA from seafood consumption.</p></div><div><h3>Methods</h3><p>We examined 1,390 National Health and Nutrition Examination Survey participants 12-19 years of age from the 2011-2018 cycles. Using logistic and linear regression adjusted for survey design variables and stratified by sex <em>a priori</em>, we estimated the associations of TBHg and methylmercury with dyslipidemia, and with total cholesterol (TC), high (HDL-C) and low-density lipoprotein cholesterol (LDL-C) and triglycerides.</p></div><div><h3>Results</h3><p>The geometric mean of TBHg in this adolescent population was 0.44 µg/L. After controlling for sociodemographic covariates, BMI, serum selenium, age at menarche (females only) and average daily intake of O3FA; TBHg was significantly associated with higher TC levels (β=3.34, 95% CI: 0.19, 6.50; p<0.05) in females but not males. Methyl Hg was also associated with increased TC, as well as decreased HDL-C in females but not males. We did not find significant associations of Hg exposure with dyslipidemia, LDL-C or triglycerides levels in either male or female adolescents. However, we observed evidence of effect modification by BMI and serum selenium for associations of TBHg with TC levels in male and female adolescents, respectively.</p></div><div><h3>Conclusion</h3><p>Our findings of elevated TC levels in females but not males necessitates further research to better understand the underlying mechanisms driving these sex-specific associations.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100047"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43023281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Antioxidants on oxidative damage, and hematological and psychological parameters in cement-exposed workers","authors":"Faezeh Darabi , Majid Keshavarzi , Narges Khanjani , Saeed Yousefinejad , Zahra Zamanian","doi":"10.1016/j.heha.2023.100060","DOIUrl":"10.1016/j.heha.2023.100060","url":null,"abstract":"<div><p>Some studies suggest that exposure to cement dust can cause oxidative stress, and have adverse effects on liver function, and hematological and psychological parameters. This study aimed to assess the effect of antioxidant vitamin supplementation on indices of oxidative stress, biochemical indicators, and psychological factors among cement plant workers. A total of 80 subjects (workers and non-exposed office employees) were divided into two groups. The intervention group that took vitamin E (400 IU)+ C (500 mg) and the control group that took placebo, for 60 days. The levels of malondialdehyde (MDA), total antioxidant capacity (TAC), superoxide dismutase (SOD) and catalase (CAT) were measured in plasma, and hematological parameters were also recorded before and after the intervention. A significant decrease in the mean level of MDA, SOD and CAT, alkaline phosphatase (ALP), alanine transaminase (ALT) and aspartate transaminase (AST) were detected. On the other hand, a significant increase in the level of TAC was observed in the workers, after the intervention. Depression and anxiety also decreased significantly after the intervention. Vitamin E and C were probably effective in reducing oxidative stress and improving mental health and liver function especially among the workers.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100060"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48035749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katharine Conaway, Sarah Lebu, Kylie Heilferty, Aaron Salzberg, Musa Manga
{"title":"On-site sanitation system emptying practices and influential factors in Asian low- and middle-income countries: A systematic review","authors":"Katharine Conaway, Sarah Lebu, Kylie Heilferty, Aaron Salzberg, Musa Manga","doi":"10.1016/j.heha.2023.100050","DOIUrl":"10.1016/j.heha.2023.100050","url":null,"abstract":"<div><p>Different fecal sludge (FS) emptying practices have been documented worldwide, but little is known about how the type of on-site sanitation system (OSS) and other factors associated with emptying and transport influence how OSSs are emptied, nor about how FS is released to the environment during emptying. This systematic literature review assessed our current knowledge on OSS fecal sludge management practices and their impacts on pathogen releases into the environment including (i) the prevalence and frequency of emptying, (ii) the types of OSS emptying practices, (iii) other factors influencing these practices, and (iv) the return pathways into the environment during emptying and transport. The analysis included 58 peer-reviewed studies examining emptying in low- and middle-income countries in Asia published between 2001 and May 2021. Mechanical emptying was the most discussed emptying method (n=39), followed by manual emptying (n=22). The most discussed emptying factor was cost (n=19), followed by OSS accessibility (n=17). Discussion on FS releases was focused on deliberate disposal into the environment, with little on unintentional spills and leaks. Remaining gaps in the literature include the quantity, pathogenicity, and fate of FS spills during emptying, the effect of OSS type on emptying, and the effectiveness of emptying interventions. More research is needed on emptying to fully understand its impact on public health and how best to facilitate safe fecal sludge management.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100050"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47501117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lead poisoning in refugee children living in the United States: A systematic review of case studies","authors":"Joanna Balza , Iwalola Awoyinka , Caitlin Kaeppler , Rachel Cusatis , Kathryn E. Flynn","doi":"10.1016/j.heha.2023.100057","DOIUrl":"10.1016/j.heha.2023.100057","url":null,"abstract":"<div><h3>Background</h3><p>Exposure to the heavy metal lead (Pb) has serious adverse health effects, particularly in children. Refugee children resettled in the United States are disparately impacted by lead. Research indicates that both pre-migration and post-migration factors play a role in this disparity. A review of case studies of lead poisoning in refugee children was performed to identify specific and unique factors influencing these outcomes.</p></div><div><h3>Methods</h3><p>Following PRISMA-P guidelines, a search was performed in collaboration with a reference librarian, incorporating keywords and subject headings related to the topic, in 7 databases: Academic Search Premier, APA PsychINFO, CINAHL, Cochrane Library, Ovid MEDLINE, Scopus, and Web of Science Core Collection.</p></div><div><h3>Results</h3><p>321 non-duplicate articles resulted from the search. After two reviewers screened the titles for eligibility against PICOS criteria, 50 studies remained. 40 studies were eliminated after an abstract review, and 7 remained after a full-text review. One additional article that did not appear in the results was identified and included. Articles discussed single case studies or case series; overall 11 cases covering 13 children with elevated blood lead level were discussed. The studies identified sources of lead poisoning in refugee children including deteriorating lead paint, imported cosmetics or medications, tobacco, traditional herbs/spices, jewelry, and traditional or religious objects.</p></div><div><h3>Conclusions</h3><p>Refugee families in the US face common environmental sources of lead exposure (e.g., lead paint) and also culturally specific exposures related to the use of imported or traditional herbs, medications, and cosmetics. Prevention efforts in refugee communities should include information related to these hazards, presented with appropriate consideration for language and culture.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100057"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46398546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valentina Marra , Silvia Valentini , Annalisa Abballe, Silvia De Luca, Fabiola Ferri, Anna Rita Fulgenzi, Nicola Iacovella, Anna Maria Ingelido, Elena De Felip
{"title":"Organochlorinated pesticides in Italian women of reproductive age: Serum levels and determinants of exposure","authors":"Valentina Marra , Silvia Valentini , Annalisa Abballe, Silvia De Luca, Fabiola Ferri, Anna Rita Fulgenzi, Nicola Iacovella, Anna Maria Ingelido, Elena De Felip","doi":"10.1016/j.heha.2023.100053","DOIUrl":"10.1016/j.heha.2023.100053","url":null,"abstract":"<div><h3>Background</h3><p>HCB, β-HCH, DDE are the organochlorinated pesticides most frequently detected for their extreme persistence and their effects on the reproductive system.</p></div><div><h3>Objectives</h3><p>The aim of the present study was to acquire information on the exposure of young Italian women to the most widespread organochlorinated pesticides.</p></div><div><h3>Methods</h3><p>549 women (20–40 years) were enrolled in six Italian regions from 2011-2013. Areas at different (presumed) exposure to persistent organic pollutants were included in all regions, such as rural, urban and industrial areas at possible incremental exposure.</p></div><div><h3>Results</h3><p>Median concentration values were 18.2 ng/g lipid base (lb) for HCB, 6.6 ng/g lb for β-HCH and 112.9 ng/g lb for DDE. Results showed higher HCB, β-HCH and DDE levels in older women compared to the 20–29 age group. Higher levels of all the three pollutants were observed in the rural areas with respect to the urban and the industrial areas. For all of the compounds, we observed a different distribution between the Italian regions. This variability is difficult to fully understand, differences in diet and lifestyle may play a role, as well as a local use of these chemicals in the past.</p></div><div><h3>Conclusions</h3><p>This study produces a large dataset of pesticide concentrations in Italian women.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100053"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44208937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of environmental volatile organic compounds with depression in adults: NHANES 2013-2018","authors":"Yin Zhuang , Xiaochen Zhang , Xiangying Sun , Zhaofeng Liu , Qiurun Yu , Chao Dong , Quanquan Guan , Qiujin Xu","doi":"10.1016/j.heha.2023.100058","DOIUrl":"10.1016/j.heha.2023.100058","url":null,"abstract":"<div><p>Volatile organic compounds (VOCs) exposure has been found to be associated with neurological dysfunction, with depression often being one of the classic symptoms of the disease, and indoor environments are more likely to be enriched with concentrations of VOCs. This cross-sectional study measured VOCs levels in whole blood, and estimated level of depression with the Patient Health Questionnaire in adults from NHANES 2013–2018. We found benzene (β = 0.40, 95%CI: 0.19, 0.61) and ethylbenzene (β = 0.22, 95%CI: 0.05, 0.39) were associated with depression adjusted for covariates in general linear regression models (GLM), and remained the consistent trend in quantile regression models. In indoor subgroup with higher VOCs level, benzene (β = 0.71, 95%CI: 0.21, 1.22), ethylbenzene (β = 0.47, 95%CI: 0.15, 0.78), and m-/p-xylene (β = 0.41, 95%CI: 0.15, 0.68) showed significant association with depression adjusted for covariates including cotinine in GLMs. Weighted quantile sum (WQS) model was used to assess the contribution of each VOC in mixed exposure. Results from WQS analyses revealed significantly positive associations between the mixed exposure and depression (β = 1.70, 95%CI: 1.18, 2.47), in which, benzene and ethylbenzene contributed 56% and 26%. We found statistically association between mixed exposure and depression before cotinine adjustment (β = 3.53, 95%CI: 2.78, 4.47). Our founding indicated a positive association between benzene and ethylbenzene exposure and depression, also with the most important effect in the mixture. Additionally, indoor VOCs sources of environmental pollution still cannot be ignored given the higher exposure level and health risk.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100058"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47311210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Economical synthesis of oxygen to combat the COVID-19 pandemic","authors":"Nidhi Bhat , Vinutha Moses , Chetan N","doi":"10.1016/j.heha.2023.100048","DOIUrl":"10.1016/j.heha.2023.100048","url":null,"abstract":"<div><p>The whole world has been affected by the COVID-19 pandemic and oxygen demand is greater than ever, but the supply is expectedly short. People in need of this oxygen are not able to receive it, especially those who cannot afford it. In addition to these issues, the oxygen from production plants is not getting delivered to hospitals on a timely basis due to insufficient availability of tankers and cylinders. It is therefore crucial to enable access of oxygen beds and cylinders to the public by developing economical methods for medical oxygen generation. Conventional methods like oxygen concentrators, the Pressure Swing Adsorption (PSA) Technique and Air Separation Units (ASUs) are either too expensive, energy intensive or feasible only on a small scale. This indicates the need to exploit methods that have not been utilized fully yet, such as Integrated Energy Systems (IES). However, reducing the cost of a process is not enough. It needs to be scaled up to have a real impact on the situation at hand. Ion Transport Membranes (ITM) are promising in this aspect as they can produce large volumes of extremely high-purity oxygen at low costs. All these methods along with their economic aspects have been discussed and then compared to identify the most feasible one.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"6 ","pages":"Article 100048"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10854204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}