Hygiene and environmental health advances最新文献

{"title":"Access to hygiene facilities and experiences of hygiene-related disease: A pilot study of unsheltered individuals in Tucson, Arizona","authors":"Bianca Nava ,&nbsp;Amanda M. Wilson","doi":"10.1016/j.heha.2024.100100","DOIUrl":"10.1016/j.heha.2024.100100","url":null,"abstract":"<div><p>Unsheltered individuals have limited access to restroom facilities. With this, many unsheltered individuals are forced to urinate, defecate, and engage in other hygiene practices outdoors. They may also lack access to necessary hygiene toiletries or wait to urinate or defecate until they are able to gain access to a facility. These challenges can lead to health issues, like urinary tract infections (UTIs), diarrhea, rashes, etc. The study objective was to understand the relationship between lack of access to basic hygiene facilities and health effects among unsheltered individuals. A verbal survey (English and Spanish) was used to explore the relationship between hygiene and unsheltered status. In Fall 2022, a researcher accompanied the homeless outreach team from El Rio Health, a Federally Qualified Health Center in Tucson, Arizona to verbally consent and recruit participants. Thirty consenting unsheltered adults ranging in ages from 29 to 68 years old participated in the study. Access to water was the greatest reported hygiene barrier, followed by access to soap, concerns for privacy, and concerns for safety. Eleven of thirty participants experienced a UTI at least once since becoming unsheltered and nine of thirty experienced a yeast infection at least once, with female participants having a statistically significant (<em>p</em> &lt; 0.05) higher rate of occurrence than male participants. In addition, 19/30 of participants experienced a rash at least once and 17/30 of participants experienced diarrhea at least once. However, 20/30 of participants did not seek medical care for their health-related issues. Low healthcare utilization when there is a high need for care highlights the importance of community outreach and care for those experiencing homelessness. Next steps include replicating the project on a larger scale to determine generalizability.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"11 ","pages":"Article 100100"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000138/pdfft?md5=7cbe95cd1cd86d51fda5035869986736&pid=1-s2.0-S2773049224000138-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex and age characteristics of thunderstorm asthma emergency department visits","authors":"M. Luke Smith ,&nbsp;Richard F. MacLehose ,&nbsp;Chris H. Wendt ,&nbsp;Jesse D. Berman","doi":"10.1016/j.heha.2024.100099","DOIUrl":"10.1016/j.heha.2024.100099","url":null,"abstract":"<div><p>Severe asthma has been shown to occur in the combined presence of high pollen and thunderstorm conditions, also known as ‘thunderstorm asthma.’ First studied as severe epidemic events, recent longitudinal work studied less dramatic but more frequent occurrences. We explore thunderstorm asthma-related emergency department visits in the Minneapolis-St. Paul metropolitan area and evaluated risk differences by sex and age. We define a thunderstorm asthma exposure event as the daily occurrence of 2 or more lightning strikes during high pollen periods, and use daily counts of asthma-related emergency department visits to estimate relative and absolute risk of severe asthma during thunderstorm asthma events for the full population and for sex and age subgroups. The overall population had a 1.06 (95 % CI: 1.02, 1.09) times higher risk of asthma-related ED visits during thunderstorm asthma events compared to days without thunderstorm asthma events. Children under 18 show no higher risk (RR 1.02; 95 % CI: 0.97 1.08), but adults 18–44 years (RR 1.08; 95 % CI: 1.02, 1.13) and 45 and up (RR 1.08; 95 % CI 1.02, 1.15) show higher relative risk. Absolute risk measures show similar patterns to the age and sex results, but age-sex subgroups show more variation in absolute vs relative risk. Our results support an association between ED visits and thunderstorm asthma and provide evidence of varying risks by sex across the life course. These differences in risk have implications for clinical treatment of this allergic type of asthma and for future research into this poorly recognized environmental exposure.</p><p>Plain Language Summary: Recent research has highlighted the existence of Thunderstorm asthma events, a phenomenon in which pollen grains rupture in the conditions that occur with a thunderstorm, releasing sub-pollen particles that are capable of triggering severe asthma in susceptible populations. Where severe asthma is a disease that usually impacts children, we find in this study that asthma ED visits associated with thunderstorm asthma events more frequently impact adults, particularly males 18–44 and females 45 and up.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"11 ","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000126/pdfft?md5=2069b0fa0173b6a2621c5feba8aca92e&pid=1-s2.0-S2773049224000126-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141846378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative multivariate analysis for high-touch surface disinfection using optimized ultraviolet-C LEDs configuration","authors":"Jahanzeb Sheikh ,&nbsp;Tan Tian Swee ,&nbsp;Syafiqah Saidin ,&nbsp;Sameen Ahmed Malik ,&nbsp;José Javier Serrano Olmedo ,&nbsp;Lee Suan Chua ,&nbsp;Matthias Tiong Foh Thye ,&nbsp;Leong Kah Meng ,&nbsp;Ma Kun","doi":"10.1016/j.heha.2024.100101","DOIUrl":"10.1016/j.heha.2024.100101","url":null,"abstract":"<div><p>UV light-emitting diodes (LEDs) have been regarded as feasible alternatives for traditional UV lamps since the early 2000s, owing to their improved safety features, environmental advantages, and efficiency. Because of the inherent challenges associated with lower intensity of LEDs over extended distances, our findings demonstrated the optimized disinfection efficiency using various LED setups. This study evaluated the antimicrobial effectiveness of single, six, and eight-LED configurations against <em>Staphylococcus aureus</em> (<em>S. aureus</em>), specifically emphasizing attaining the utmost disinfection efficiency within an extended range of up to 60 cm. With an 8-LED configuration, the study achieved a substantial reduction of 6.10×10⁴ CFU/mL from an initial level of 5.20×10⁹ CFU/mL, corresponding to 4.9-log₁₀ inactivation, requiring a dose of 264 µJ-cm⁻². 2.9-log₁₀ inactivation was achieved using a 6-LED, yielding lower yet comparable efficiency requiring 192 µJ-cm⁻² of dose. However, with 60 µJ-cm⁻² of dose, a single LED could only reduce the bacterial burden from the initial level to merely 0.2-log₁₀ inactivation, corresponding to 2.9 × 10⁹ CFU/mL, under similar exposure settings. In conclusion, UV-LEDs show promise for disinfection, with LED configuration and distance significantly impacting their efficiency, holding perspective for various applications, particularly within healthcare facilities.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"11 ","pages":"Article 100101"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277304922400014X/pdfft?md5=4ada6873c8640341da8ccf8af922dfad&pid=1-s2.0-S277304922400014X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141960337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between prolonged dual use of cigarettes and E-cigarettes and psychosocial factors among U.S. Smokers: Secondary data analysis from the 2013 to 2019 PATH study","authors":"Rui Chen ,&nbsp;Angela Aherrera ,&nbsp;Miranda R. Jones ,&nbsp;Elizabeth A. Stuart ,&nbsp;Meghan F. Davis ,&nbsp;Ana M. Rule","doi":"10.1016/j.heha.2024.100103","DOIUrl":"10.1016/j.heha.2024.100103","url":null,"abstract":"<div><h3>Objective</h3><p>Dual use of combustible cigarettes and e-cigarettes is common among U.S. tobacco users, yet misperceptions about the harm of dual use persist, often oversimplifying its multifaceted exposure and health impacts. To address this gap, we evaluated the association of prolonged dual use (consecutive use for more than 1 year) with psychosocial factors, including perceptions of absolute and relative harm of e-cigarettes, social norms, and intentions to quit smoking, among U.S. adult smokers over time.</p></div><div><h3>Methods</h3><p>Using the data from Waves 1 to 5 (2013–2019) from the Population Assessment of Tobacco and Health (PATH) Study, we characterized dual use and prolonged dual use by sociodemographics and psychosocial factors among U.S. adult smokers. We examined the association between dual use, including prolonged dual use, and psychosocial factors over time using logistic regression.</p></div><div><h3>Results</h3><p>Dual use of smokers decreased from 19.8 % in 2013 to 16.4 % in 2019, and prolonged dual use among dual users decreased from 40.0 % in 2013 to 27.4 % in 2019. Prolonged dual users, independent of frequency of use, presented significantly higher cigarette dependence than temporary dual users. The perception of absolute e-cigarette harm (perceiving e-cigarettes as very or extremely harmful) was negatively associated with prolonged dual use. No significant association was found between prolonged dual use and perception of relative e-cigarette harm (perceiving e-cigarettes are less harmful that cigarettes) as well with intentions to quit smoking and beliefs that most people disapprove of e-cigarette use.</p></div><div><h3>Conclusion</h3><p>: Increased perceptions of absolute harm of e-cigarettes, rather than relative harm, appear to decrease prolonged dual use. Public health strategies should consider further emphasis in educating users of the absolute harm, as opposed to endorsing e-cigarette use as a harm reduction alternative, in their tobacco cessation efforts to further discourage dual use.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"11 ","pages":"Article 100103"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000163/pdfft?md5=12e5d20389317eb976e7821e55a0355f&pid=1-s2.0-S2773049224000163-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141848153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In the wake of a surge in naegleria fowleri infections: Overcoming challenges and implementing protective measures in Pakistan","authors":"Juvairia Yousuf,&nbsp;Laiba Afaq,&nbsp;Uzma Aslam,&nbsp;Nabahat Shafi,&nbsp;Zainab Syyeda Rahmat","doi":"10.1016/j.heha.2024.100095","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100095","url":null,"abstract":"","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100095"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000084/pdfft?md5=7f3e86ea42590709e3aef105dfa2b95c&pid=1-s2.0-S2773049224000084-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140950313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex toys for pleasure, but there are risks: In silico toxicity studies of leached Micro/Nanoplastics and phthalates","authors":"Christian Ebere Enyoh,&nbsp;Qingyue Wang","doi":"10.1016/j.heha.2024.100092","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100092","url":null,"abstract":"<div><p>The widespread use of sex toys has sparked concerns about potential health risks associated with the leaching of micro/nanoplastics (M/NPs) and phthalates. In this <em>in silico</em> toxicity analysis, we investigated the immunotoxicity potential of compounds mechanically produced from sex toys. The research focuses on understanding their interactions with critical human cytochrome P450 enzymes (CYP34A and CYP2D6), which are central to drug metabolism and immune function. Four types of M/NPs (polyethylene terephthalate - PET, polyvinyl chloride - PVC, polydimethylsiloxane - PDMS, polyisoprene) and eight phthalates (Diethyl phthalate - DEP, Bis(4-methyl-2-pentyl) phthalate, Bis(2-methoxyethyl) phthalate, Benzyl butyl phthalate - BBP, Dibutyl Phthalate - DBP, Diethylhexyl phthalate - DEHP, Dinonyl phthalate - DNP, Di-n-octyl phthalate - DnOP) from sex toys were analyzed. Molecular dynamics and docking simulations were conducted to assess the binding affinity of these compounds to the enzymes. PET exhibited the highest toxicity, with a binding affinity of -8.3 kcal/mol and -8.9 kcal/mol for CYP3A4 and CYP2D6, respectively, surpassing control values (-7.8 kcal/mol and -6.3 kcal/mol). BBP showed considerable toxicity, binding strongly to CYP3A4 (-7.8 kcal/mol) and CYP2D6 (-9.1 kcal/mol). PDMS and DEP were the lowest toxic compounds in both groups. Molecular interactions revealed hydrogen bonds, pi interactions, and unfavorable donor-donor effects between compounds and specific amino acid residues within the enzymes. While these <em>in silico</em> findings provide insights, they underscore the need for comprehensive chemical analyses and absorption studies to validate health risks. This research emphasizes the necessity of evaluating the toxicity of M/NPs and phthalates from sex toys, promoting further investigations to protect individuals' health during product use.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100092"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000059/pdfft?md5=a2252bdaaf9513a516dfe261d09dc81e&pid=1-s2.0-S2773049224000059-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140555786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coal-fired PM2.5 induces endothelial cell injury and the expression of atherosclerosis-related adhesion molecules: Involvement of the p38 and JNK signaling pathways","authors":"Yanping Zhang ,&nbsp;Hanyun Zheng ,&nbsp;Siqi Wang ,&nbsp;Xuetao Wei ,&nbsp;Qin Li ,&nbsp;Feifei Wang","doi":"10.1016/j.heha.2024.100093","DOIUrl":"10.1016/j.heha.2024.100093","url":null,"abstract":"<div><p>It has been reported that PM_2.5 causes endothelial cell injury and promotes atherosclerosis. However, the exact mechanism through which coal-fired PM_2.5 induces endothelial cell injury, and the involvement of the p38 and JNK signaling pathways in this process remain unclear. In this study, EA.hy926 cells were exposed to coal-fired PM_2.5 at concentrations of 25, 50, and 100 μg/mL, and the toxic effects were observed. The phosphorylation of the JNK and p38 signaling pathways was investigated through western blot analysis. Additionally, the expression of adhesion molecules (ICAM-1 and E-selectin) was assessed using ELISA and flow cytometry. Changes in cellular toxicity and adhesion molecules were evaluated after pretreatment with the p38 inhibitor SB203580 (10 μM) and the JNK inhibitor SP600125 (25 μM). We observed that exposure to coal-fired PM_2.5 led to a decrease in cell survival rate and proliferation while promoting apoptosis. Exposure to coal-fired PM_2.5 promoted the expression of ICAM-1 and E-selectin, as well as the phosphorylation of p38 and JNK in EA.hy926 cells. After using p38 and JNK inhibitors, there was an observed increase in cell survival rate and proliferation, accompanied by a decrease in apoptosis. The levels of ICAM-1 and E-selectin showed no significant changes with the addition of p38 and JNK inhibitors. Our results indicated that coal-fired PM_2.5 caused cellular toxicity and increased the levels of ICAM-1 and E-selectin. The p38 and JNK signaling pathways might play a role in the reduction of cell viability, while the regulation of ICAM-1 and E-selectin might not be influenced by these pathways.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100093"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000060/pdfft?md5=c729f6fa76ea09161f111e6d024e74cd&pid=1-s2.0-S2773049224000060-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140761194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between metal exposure and body mass index of preschool children of Shaanxi, China","authors":"Yan Zhao ,&nbsp;Zhaoyang Li ,&nbsp;Xinyue Wen ,&nbsp;Hongqiu Li ,&nbsp;Huifang He ,&nbsp;Jing Han","doi":"10.1016/j.heha.2024.100094","DOIUrl":"10.1016/j.heha.2024.100094","url":null,"abstract":"<div><p>There are few studies on the association between polymetallic exposure and obesity in preschool children, and the conclusions are inconsistent. The study aimed to explore the association between urine metals and body mass index (BMI). For 342 preschool children in the industrial park of Shaanxi, China, uniformly trained investigators collected basic information of preschoolers and measured height and weight. Morning urine were collected, and BMI were calculated. We measured concentrations of 22 urine metals by quadrupole inductively coupled plasma-mass spectrometry (ICP-MS).</p><p>The least absolute shrinkage and selective operator (LASSO) regression model was used to screen urine metals larger impact on BMI. In the polymetallic exposure model, generalized linear regression was used to explore the relationship between the selected urine metals and BMI. The overall relationship between urine metals and BMI was analyzed using restricted cubic spline (RCS). The interaction method was used to explore the influence of metal-metal interaction on BMI. After adjustment for covariates, ln-transformed urinary copper (Cu) levels and urinary molybdenum (Mo) levels were negatively associated with BMI, (Cu, β=−1.219, 95% CI: −2.047, −0.391, <em>P</em>&lt;0.05; Mo, β=−0.797, 95% CI: −1.508, −0.087, <em>P</em>&lt;0.05). Polymetallic model showed similar results. Both ln-transformed urinary Cu levels and urinary Mo levels were negatively correlated with BMI (Cu: β=−1.556, 95% CI: −2.488, −0.624, <em>P</em>&lt;0.05; Mo: β=−0.915, 95% CI: −1.817, −0.013, <em>P</em>&lt;0.05). The results of RCS visually demonstrate that Cu and BMI are non-linearly correlated (<em>P</em> _total &lt; 0.001, <em>P</em> _nonliearity = 0.005), Mo and BMI are linearly correlated (<em>P</em> _total &lt; 0.05, <em>P</em> _nonliearity = 0.099) Urinary Cu was negatively correlated with BMI nonlinearly in preschool children, and there was a borderline interaction between urinary Mo and Cu levels.</p><p>Further researches are needed to validate these associations and reveal underlying mechanisms</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100094"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000072/pdfft?md5=d82dff54982235e51c7423cc0d6bc773&pid=1-s2.0-S2773049224000072-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141048416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salmonella Typhimurium outbreak caused by contaminated chocolate highlights the importance of food hygiene and a socially responsible food chain","authors":"Hannu Korkeala ,&nbsp;Tarja Koskela ,&nbsp;Katri Jalava","doi":"10.1016/j.heha.2024.100096","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100096","url":null,"abstract":"<div><p>Recent global salmonella outbreak was linked to chocolate products but potential role of cocoa beans has been neglected. Chocolate related salmonella outbreaks have occurred mostly during low cocoa price levels. Food business operators should ensure hygiene at all production stages. These outbreaks highlight corporate social responsibility while demonstrating the need of multi-professional approaches.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100096"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000096/pdfft?md5=e8ae9bc974fc0de81c6175b100e0fae3&pid=1-s2.0-S2773049224000096-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140952408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise attenuates the association between pyrethroid exposure and sleep disorders in male adults","authors":"Jing Shao ,&nbsp;Jing Yang ,&nbsp;Jia Lv ,&nbsp;Tao Wang ,&nbsp;Huiru Chen ,&nbsp;Xinyu Zhang ,&nbsp;Jingjing Li ,&nbsp;Min Wang ,&nbsp;Lihua Xu ,&nbsp;Yichao Huang ,&nbsp;Xiuhong Meng","doi":"10.1016/j.heha.2024.100091","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100091","url":null,"abstract":"<div><h3>Background</h3><p>Pyrethroids are widely used in agriculture and household pest management as one of the top three insecticides globally, yet the neurobehavioral impacts of human exposure to these chemicals have attracted increasing concern.</p></div><div><h3>Objective</h3><p>The purpose of this study was to examine the associations between pyrethroid exposure and sleep disorders and whether exercise could attenuate these associations.</p></div><div><h3>Methods</h3><p>We analyzed cross-sectional data from the 2007-2014 National Health and Nutrition Examination Survey to study the association between pyrethroid pesticide exposure and sleep disorders. The exposure level of pyrethroid metabolites in urine samples was measured. Physician diagnosis of sleep disorders was used to determine sleep disorders. Exercise level was judged by self-reported physical activity from the interviews.</p></div><div><h3>Results</h3><p>Of the 5947 participants, sleep disorders had a weighted prevalence of 9.0 %, representing an approximation of 186,140,757 patients nationwide. We found a sex-specific association between high levels of 3-PBA and elevated risk of sleep disorders diagnosis in men (OR: 1.87; 95 % CI: 1.150–3.042; <em>P</em> = 0.01). In addition, less physical activity was associated with higher rates of sleep disorders as pyrethroid exposure levels increased (OR: 1.98; 95 % CI: 1.152–3.388; <em>P</em> = 0.02).</p></div><div><h3>Conclusion</h3><p>This study further confirmed that pyrethroid exposure is associated with an elevated risk of sleep disorders in men. More importantly, we reported for the first time that vigorous physical activity attenuates the correlation between pyrethroid exposure and sleep disorders.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100091"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000047/pdfft?md5=ca407c61ebfb2d5f28868cc8f2ac11d2&pid=1-s2.0-S2773049224000047-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140555783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}