Global pediatrics最新文献

{"title":"Socio-economic burden of sickle cell disease on families attending sickle cell clinic in Kano state, northwestern Nigeria","authors":"I.I. Beli ,&nbsp;L.A. Ali ,&nbsp;C.C. Onuoha ,&nbsp;M. Jasseh ,&nbsp;M. Zentar ,&nbsp;N. Belakoul ,&nbsp;Y. Layadi ,&nbsp;J.A. Deblui ,&nbsp;M. Fathi ,&nbsp;A.H. Sani ,&nbsp;A.G. Adamu ,&nbsp;M.A. Mbahi ,&nbsp;T. Laachfoubi ,&nbsp;M. Umar","doi":"10.1016/j.gpeds.2024.100193","DOIUrl":"10.1016/j.gpeds.2024.100193","url":null,"abstract":"<div><p>This study aimed to assess the socio-economic impact of sickle cell disease (SCD) on families of patients receiving care at the SCD clinic of Aminu Kano Teaching Hospital (AKTH) in Kano, Northwest Nigeria. The research adopted a descriptive cross-sectional approach, involving the participation of 273 individuals selected through a multi-stage sampling method. Data was gathered using semi-structured interviews and subjected to analysis using SPSS software. The study achieved a 100 % response rate, with 84 % of the participants being females. The average age of the participants was 35.1 ± 8.6 years, and a significant proportion (79.9 %) reported a monthly income of thirty thousand naira or less. The findings of the study revealed that SCD had a notable social impact, affecting 93.5 % of participants occasionally and 5.8 % most of the time. Furthermore, a substantial financial burden was experienced by 54.2 % of respondents most of the time and 45.1 % occasionally. The research also highlighted the significant influence of SCD on guardians' employment status, income levels, time spent in hospitals, medical expenditures, and overall quality of life. These findings underscore the considerable social and financial challenges faced by guardians of SCD patients. Study results supports prioritizing affordable healthcare access for families affected by SCD to alleviate the burdens they face.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100193"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000617/pdfft?md5=c25cbc96f5e4dbf45eae3ddbb8b6ef31&pid=1-s2.0-S2667009724000617-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141276291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covid lockdown and repaying the immunity debt in children","authors":"Peng Han ,&nbsp;Kunling Shen","doi":"10.1016/j.gpeds.2024.100195","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100195","url":null,"abstract":"<div><p>Non-pharmaceutical interventions (NPIs) implemented during the SARS-CoV-2 pandemic have been proven effective. While reducing SARS-CoV-2 transmission, NPIs also reduced children's exposure to other pathogens, leading to a decline in the incidence of many viral and bacterial infections. The reduction in contact with viruses and bacteria could result in insufficient immune stimulation of pathogens in the population, leading to an increase in susceptible populations and a decline in herd immunity, which form the immunity debt during the SARS-CoV-2 pandemic. Immunity debt can impact the pattern of seasonal pathogens, increase the incidence and severity of invasive infections, and potentially raise the risk of allergic diseases in children. Immunization, continuing to implement NPIs, pathogen monitoring, and health education are important measures to repay immunity debt. Besides, trained immunity, referring to the memory immunity produced by the innate immune system upon re-stimulation, can be employed as a non-specific measure to prevent the spread of pathogens. The protective effect of trained immunity can be used as a temporary preventive measure for emerging infectious diseases and create conditions for vaccine development.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100195"},"PeriodicalIF":0.0,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000630/pdfft?md5=476c9da9b0c328eb8aeb152f93d26eaa&pid=1-s2.0-S2667009724000630-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141292324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The adverse effects of vaping in young people","authors":"Judith Meehan ,&nbsp;Mairead Heffron ,&nbsp;Helen Mc Avoy ,&nbsp;Ciara Reynolds ,&nbsp;Louise Kyne ,&nbsp;Des W Cox","doi":"10.1016/j.gpeds.2024.100190","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100190","url":null,"abstract":"<div><p>Vapes or e-cigarettes are battery operated devices that heat a liquid until it becomes a vapour, which is inhaled. Typically, e-liquids contain nicotine, different flavourings, and propylene glycol. Vaping devices are either disposable vapes or rechargeable. Vapes were initially developed as stop smoking aid but they have now become a recreational product popular among teenagers.</p><p>Vaping has increased at an alarming rate among teenagers and young adults in Ireland. The European Schools Project for Alcohol and Other Drugs (ESPAD) survey 2019 showed that almost 4 in 10 Irish 16-year-olds had tried vaping and 15 % currently use them. More worrying is the dramatic rise in the use of disposable vapes in recent years. An Action on Smoking and Health (ASH) UK survey data revealed a 9-fold increase from 2021 to 2023 in their use (7.7 % to 69 %) among 11–17-year-old vapers.</p><p>A combination of clever marketing by vaping companies, a strong social media presence, attractive flavours and easy accessibility has contributed to the increasing use of vapes by young people.</p><p>Exposure of children and adolescents to nicotine in vaping solutions can lead to long-term negative impacts on brain development, as well as addiction. Many teenagers who vape experience poor concentration, anxiety, mood disorders and sleep disturbance. A paper from NEJM in 2022 reported a case series where chronic vaping resulted in small airway fibrosis of the airways. A systematic review conducted in 2021 concluded that teenager vapers were three to five times more likely to take up tobacco smoking when compared with non-vapers.</p><p>Strong legislation is required to ban the sale of disposable vapes to teenagers along with controls on marketing online. Healthcare Professionals should ask and counsel their patients about vaping. Increased public awareness and education for Health care professionals on teenage vaping needs to be addressed.</p><p>Vaping has become a global public health issue that must be addressed urgently.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100190"},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000587/pdfft?md5=ad73dbc1bf98177f7550da76206ee5d9&pid=1-s2.0-S2667009724000587-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141243710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary Incontinence in childhood","authors":"L. Szabó","doi":"10.1016/j.gpeds.2024.100187","DOIUrl":"10.1016/j.gpeds.2024.100187","url":null,"abstract":"<div><p>In childhood, all forms of adult urinary incontinence occur, only the underlying causes and their distribution may be different.</p><p>Patients and Methods</p><p>5725 children (aged 0–18 years) underwent urodynamic examination in the Velkey László Child Health Center, Miskolc, and in the Heim Pál National Pediatric Institute, Budapest between 1986 and 2023.</p><p>Results: 675 children had urinary incontinence. 471/1335 children with nocturnal enuresis had non-monosymptomatic enuresis with urge incontinence. 115 children have dysfunctional voiding.</p><p>Videourodynamic study showed overactive bladder dysfunction in 31 %, neurogenic bladder dysfunction in 7 %, urine outflow obstruction in 3 %, and vaginal reflux in 2 % children.</p><p>Conclusion: The disorder of urinary retention and emptying occurs as a result of the disorder of the coordinated functioning of the bladder emptying muscle, the detrusor and the closing muscle group, the sphincter. Urge incontinence, overactive bladder function is the most common form of UI in childhood. Anamnesis and uroflow examination are sufficient to establish an accurate diagnosis. Unfortunately, anticholinergic medication is still the accepted treatment for children, with many side effects.</p><p>Incontinence after urination is most often caused by vaginal reflux, which can be easily detected with a video urodynamic examination.</p><p>Nocturnal enuresis is one of the most common problems in early childhood. Simple explanation, the bladder fills up at night, either because there is a lot of urine output at night, or because the bladder capacity is small. The next step is that the child does not wake up with a full bladder. He sleeps so deeply that he does not respond to the urge to urinate during sleep, and he wets the bed or wakes up and becomes a nocturnal urinates.</p><p>Most childhood urinary incontinence can be successfully treated and resolved in childhood.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100187"},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000551/pdfft?md5=8c26ae920c3bef33d027eb1955ac7042&pid=1-s2.0-S2667009724000551-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in undergraduate and postgraduate education- bedside, simulation and E-learning","authors":"Edna Roche","doi":"10.1016/j.gpeds.2024.100188","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100188","url":null,"abstract":"<div><p>Clinical bedside teaching the cornerstone of medical education in the 19^th century has been shaped and developed by changes in healthcare delivery and work practices. Developing skilled clinicians to work and thrive in these complex environments requires innovative and adaptive strategies. In this rapidly changing environment compounded by a shorter duration of training, there is an increasing focus on the student learner, team-based working and the development of professionalism. The continuum of medical education from undergraduate through postgraduate to continued professional development has been greatly enhanced by the adoption of new strategies and technologies. Simulation is long established in medical education and its benefits well recognised. Technological developments including Artificial Intelligence have supported and enhanced the quality of simulation in medical education. There is a broad range of simulation available with varying degrees of fidelity, as required, culminating in immersive virtual reality. The challenges for medical educators of the Covid-19 pandemic, with closure or restricted access to clinical patients, wards and classrooms, resulted in rapid restructuring of teaching programs and for many to move “on-line”. This resulted in widespread rapid adoption of technologically driven medical education, with E-learning, blended learning and innovative strategies to increase student engagement. The seismic changes in medical education necessitated by the Covid-19 pandemic coupled with the upskilling of medical educators and technological advances, should result in an exciting period of continued innovation in medical education, a second “Golden Era” and enhance medical education for many years to come.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100188"},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000563/pdfft?md5=9e15185daaf2f4d24b3f8134d56e9c95&pid=1-s2.0-S2667009724000563-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141095285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the growing burden of obesity, diabetes and asthma in children and adolescents: The role of primary health care and the WHO Pocket book in Europe for a healthy future","authors":"Sophie Jullien,&nbsp;Susanne Carai,&nbsp;Martin W. Weber","doi":"10.1016/j.gpeds.2024.100186","DOIUrl":"10.1016/j.gpeds.2024.100186","url":null,"abstract":"<div><p>The burden of obesity, diabetes mellitus and asthma remains a significant public health issue worldwide. These conditions are associated with premature deaths and a reduced quality of life. Primary health care plays a key role in the prevention, detection, and management of noncommunicable diseases in childhood, including diabetes and asthma. Health promotion is crucial for a healthy life from early childhood, preventing from obesity, a sedentary lifestyle, exposure to tobacco smoke, and other risk factors associated to noncommunicable diseases. Asthma and type 1 diabetes mainly begin in childhood; thus, recognition and early detection at the primary health care level are essential. In the long term, management of children with chronic diseases requires regular follow-up and cooperation with a specialized team. Care coordination by the primary health care provider is key for optimal control of the disease and development of the child or adolescent in the physical, emotional, and social spheres. Over-referral for diagnosis and follow-up is associated with unnecessary specialist overload, patient anxiety, and financial burden for the families and the health system. Clear criteria and referral pathways with efficient communication between the professional team members are essential to empower primary health care providers, avoid unnecessary referrals, and optimize the care and quality of life of children and adolescents with chronic diseases.</p><p>The WHO Pocket book of primary health care for children and adolescents was recently developed to address knowledge gaps and improve the diagnosis and management of children and adolescents at the outpatient level. It dedicates an entire chapter to health promotion and disease prevention with counselling messages addressed to children, adolescents and their families; provides guidance for the diagnosis and management of asthma, diabetes and other chronic diseases; and includes additional considerations for adolescents living with chronic conditions.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100186"},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266700972400054X/pdfft?md5=7e2b25d0a1ebbb30afb4bc26bdfc309a&pid=1-s2.0-S266700972400054X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141034535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transitioning from thoracotomy to thoracoscopy for esophageal atresia in an LMIC setting","authors":"Dr Hansraj Mangray ,&nbsp;Dr Sanele Madziba ,&nbsp;Dr Yashlin Govender ,&nbsp;Dr Trudy Martin ,&nbsp;Dr Chantal Rajah ,&nbsp;Dr Pieter H Mare ,&nbsp;Prof Damian L Clarke","doi":"10.1016/j.gpeds.2024.100185","DOIUrl":"10.1016/j.gpeds.2024.100185","url":null,"abstract":"<div><h3>Introduction</h3><p>Although the benefits of thoracoscopic esophageal atresia repair (TEAR) are well documented, there has been resistance to the uptake of this approach in low- and middle-income countries. This study reviews a single unit's experience introducing TEAR in a South African state sector tertiary hospital.</p></div><div><h3>Method</h3><p>We describe how we set up MIS for esophageal atresia (EA) at our centre. All neonates with EA managed at our institution from January 2016 to January 2022 were included. Excluded patients included those who were not operated on or if data was missing. We compared the different approaches for managing type C EA in our setting. We analyzed the data using the Mann-Whitney U test.</p></div><div><h3>Results</h3><p>Sixty-five patients were managed with EA over the study duration. There were 54 patients who had type C EA. Thirty-nine patients underwent thoracotomy to repair the defect, and eighteen underwent TEAR, of which sixteen were completed thoracoscopically. There was a statistically significant difference in weight (p-value 0.035), gestational age (p-value 0.002), and age at operation (p-value 0.004) between the groups treated by TEAR and OEAR (open esophageal atresia repair). There was a small median difference in the operative time between TEAR and OEAR of 20 min. The mortality in the OEAR group was higher (20.5 %) compared to the TEAR group (5.5 %), with a p-value of 0.094.</p></div><div><h3>Conclusion</h3><p>A dedicated quality improvement program focused on introducing MIS for EA can produce results comparable to the open procedure in an LMIC setting.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100185"},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000538/pdfft?md5=bae4d2ad4fcfe34f7f4351c46a64385e&pid=1-s2.0-S2667009724000538-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141035482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum regarding missing Ethical Statements in Previously Published Articles","authors":"","doi":"10.1016/j.gpeds.2024.100183","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100183","url":null,"abstract":"","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"8 ","pages":"Article 100183"},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000514/pdfft?md5=8d2eddd438dea0c9b075e6cb60797340&pid=1-s2.0-S2667009724000514-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140914025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving rates of adolescent suicide risk screening in a primary pediatric clinic, a quality improvement project","authors":"Janet Lee ,&nbsp;Gabriela Araujo ,&nbsp;Emma Price","doi":"10.1016/j.gpeds.2024.100184","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100184","url":null,"abstract":"<div><p>In recent years, adolescents have experienced rising rates of suicidal ideation. Though pediatricians in our clinic were screening for depression, suicide risk screens were not completed. We designed a quality improvement (QI) project with the goal to increase the rate of suicide risk screening by 20 %, and improve clinicians’ attitudes toward the electronic health record (EHR) for mental health screening by 20 %. Baseline analyses included chart review and a provider survey. Suicide risk screen tools were built with decision-support into the EHR. After provider education was completed, the EHR-based interventions were implemented. Post-intervention, suicide risk screening completion increased from 8.8 % to 95 %. Provider attitudes towards the EHR also improved. This QI project demonstrates that implementing EHR tools that are provider-informed can help to improve suicide risk screening rates, streamline workflows, and help improve clinicians’ attitudes towards the EHR.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100184"},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000526/pdfft?md5=5c2ac3a3cf63bd5208ad99d7585cd694&pid=1-s2.0-S2667009724000526-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140948707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Neurodevelopmental outcome of a child with UPD(16)mat: A case report”","authors":"Maria Novelli ,&nbsp;Valeria Mammarella ,&nbsp;Francesca Calandriello ,&nbsp;Sara Temofonte ,&nbsp;Marina Goldoni ,&nbsp;Ilaria Macchiarulo ,&nbsp;Paolo Versacci ,&nbsp;Antonio Pizzuti ,&nbsp;Jessica Petrilli ,&nbsp;Carlo Di Brina ,&nbsp;Barbara Caravale","doi":"10.1016/j.gpeds.2024.100179","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100179","url":null,"abstract":"<div><h3>Objective</h3><p>UPD(16)mat is a rare genetic condition characterized by intrauterine growth deficiency and multiple congenital malformations. To the best of our knowledge, neurodevelopmental disorders have never been described in association with UPD(16)mat, nor a comprehensive neuropsychological profile of a UPD(16)mat child has never been delineated. We present a young patient diagnosed with UPD(16)mat, and provide clinical description, comprehensive neurodevelopmental, neuropsychological and neurological assessment.</p></div><div><h3>Method</h3><p>Neuropsychological examination included global neurodevelopment and intelligence scales, as well as specific trials for gross-motor, fine-motor and perceptual motor abilities, and language skills.</p></div><div><h3>Results</h3><p>The patient shows multiple congenital anomalies, including oesophageal atresia, mild bone alterations, hypospadias, persistent left superior vena cava. The neurodevelopmental evaluation demonstrates a speech disorder, signs of gross and fine motor skills difficulties, balance and visuo-motor deficit.</p></div><div><h3>Conclusion</h3><p>Evidence from this study indicates that UPD(16)mat may present neuropsychological and/or minor neurological abnormalities. Monitoring both the early and late neurodevelopmental outcomes during childhood is recommended for the chance of an early intervention.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100179"},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000472/pdfft?md5=e8ef4729a354631ed3fd25c295dc4c44&pid=1-s2.0-S2667009724000472-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140901199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}