Amanda Wurz, Emma McLaughlin, Anna Janzen, Hannah Cripps, Longlong Huang, Heather Molina, Lauren Cowley, Julianna Dreger, S Nicole Culos-Reed, Kaitlyn Quinn, In Memory Of Lisa Currey, Maria-Hélèna Pacelli, Melissa Coombs, Sundas Shamshad
{"title":"A Protocol for a Mixed Methods, Single-Arm, Hybrid Effectiveness-Implementation Trial Evaluating a 12-week Yoga Intervention Delivered by Videoconference for Young Adults Diagnosed With Cancer.","authors":"Amanda Wurz, Emma McLaughlin, Anna Janzen, Hannah Cripps, Longlong Huang, Heather Molina, Lauren Cowley, Julianna Dreger, S Nicole Culos-Reed, Kaitlyn Quinn, In Memory Of Lisa Currey, Maria-Hélèna Pacelli, Melissa Coombs, Sundas Shamshad","doi":"10.1177/27536130241305130","DOIUrl":"10.1177/27536130241305130","url":null,"abstract":"<p><strong>Background: </strong>Cancer among young adults (18-39 years) is relatively rare, but remains a leading cause of disability, morbidity, and mortality. Identifying strategies to support young adults' health following a diagnosis of cancer is important. Yoga may enhance health and could be delivered by videoconference. However, little research exploring yoga, and no research exploring videoconference delivery of yoga has been conducted with this cohort. We worked with young adults affected by cancer and developed, piloted, and refined a yoga intervention delivered by videoconference.</p><p><strong>Objective: </strong>To evaluate our yoga intervention in a full-scale, mixed methods, single-arm, hybrid effectiveness-implementation trial.</p><p><strong>Methods: </strong>Young adults 18 years or older, diagnosed with cancer between the ages of 18-39 years of age, and at any stage along the cancer trajectory are eligible. Participants receive 2 yoga classes/week over 12-weeks by videoconference and complete assessments at baseline, post-intervention, and 6- and 12-month follow-ups. Assessments include self-reported questionnaires (ie, stress, yoga barriers, physical activity behaviour, fatigue, cognition, cancer-related symptoms, general health, health-related quality of life, self-compassion, mindfulness, group identification), physical assessments (ie, aerobic endurance, flexibility, range of motion, balance, functional mobility), and a semi-structured interview (post-intervention only; exploring perceptions of acceptability, feasibility, and experiences). Quality improvement cycles occur every 6 months. Repeated measures analysis of variance will be conducted to explore effectiveness, descriptive statistics and responder/non-responder analyses will be used to explore implementation, and qualitative interview data, analyzed using content analysis and reflexive thematic analysis, will bolster effectiveness and implementation findings.</p><p><strong>Discussion: </strong>As the first full-scale trial to evaluate yoga delivered by videoconference for this cohort, findings will make substantial contributions to young adults' supportive cancer care.</p><p><strong>Conclusion: </strong>This protocol, reporting on yoga delivered by videoconference for young adults diagnosed with cancer, will enhance transparency and reproducibility and provide a reference for forthcoming trial results.</p><p><strong>Trial registration: </strong>NCT05314803 at clinicaltrials.gov.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241305130"},"PeriodicalIF":0.0,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to \"Earworms in the Amusic Mind? Questionnaire Investigation in Congenital Amusia\".","authors":"","doi":"10.1177/27536130241302690","DOIUrl":"https://doi.org/10.1177/27536130241302690","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1177/27536130241245432.].</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241302690"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11610020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum to \"Using PROMIS Methodology to Create Self-Report Measures of Mindfulness and Related Concepts\".","authors":"","doi":"10.1177/27536130241303837","DOIUrl":"https://doi.org/10.1177/27536130241303837","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1177/27536130241290771.].</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241303837"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11610018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mary Jackson, Paula Gardiner, Jennifer Leeman, Isabel Roth
{"title":"Clinician Experiences With Integrative Group Medical Visits for Chronic Pain.","authors":"Mary Jackson, Paula Gardiner, Jennifer Leeman, Isabel Roth","doi":"10.1177/27536130241304772","DOIUrl":"10.1177/27536130241304772","url":null,"abstract":"<p><strong>Background: </strong>The well-being of healthcare teams is an important consideration when seeking to improve patient experience and quality of care. Prior studies have found that changes to working conditions are most effective in improving clinician well-being. Integrative Group Medical Visits (IGMVs) modify working conditions in ways that have potential to improve clinician experience.</p><p><strong>Objective: </strong>The objective of this study was to understand healthcare teams' experiences with IGMVs.</p><p><strong>Methods: </strong>In this qualitative study, interviews were conducted via Zoom and telephone with 21 clinicians, administrators, and staff from safety-net healthcare settings throughout the United States (U.S.) who have implemented IGMVs for patients with chronic pain. Interviews included questions about clinician experience, well-being, and satisfaction with the IGMV model. Interviews were recorded, transcribed, and coded using thematic content analysis by a team of trained qualitative researchers.</p><p><strong>Results: </strong>The authors identified five themes describing how IGMV positively affected clinician well-being: organizational supports, human-centered engagement, collaboration with an interprofessional team, provision of guideline-concordant care, and enhanced meaning and purpose for the clinicians.</p><p><strong>Conclusion: </strong>The current study was the first to use interviews from healthcare teams who have implemented IGMV to assess their experience. The themes identified warrant further investigation into IGMVs as a strategy to promote clinician well-being and mitigate aspects of burnout.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241304772"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11605745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dhanesh D Binda, Angelique C Harris, Taralyn Tan, Krisztina Fischer, Rose L Molina, Darshan Mehta
{"title":"Examining the Role of Medical School Faculty in Developing Students' Cultural Humility Skills: Insights From a Single-Center Multimethod Study.","authors":"Dhanesh D Binda, Angelique C Harris, Taralyn Tan, Krisztina Fischer, Rose L Molina, Darshan Mehta","doi":"10.1177/27536130241305087","DOIUrl":"https://doi.org/10.1177/27536130241305087","url":null,"abstract":"<p><strong>Background: </strong>While the Liaison Committee on Medical Education emphasizes the teaching of cultural competence in medical education, the concept of cultural humility, focusing on self-reflection and lifelong learning, has been proposed as a more effective approach. Although there have been numerous discussions on both topics, understanding how faculty in clinical settings help students develop cultural humility skills remains limited.</p><p><strong>Objective: </strong>Our multimethod study utilized a survey and semi-structured interviews to identify strategies that faculty at one institution use to help students develop cultural humility skills.</p><p><strong>Methods: </strong>We administered a 10-question survey to assess faculty demographics, teaching characteristics, and familiarity with cultural humility. Participants most familiar with cultural humility were invited for semi-structured interviews. Survey data were analyzed with descriptive statistics, and interview data were thematically analyzed to identify key teaching strategies.</p><p><strong>Results: </strong>In our study of 49 medical faculty members, the majority of participants were female (61%) and predominantly White (67%), covering a wide range of specialties and years of teaching. Of the participants, 74% expressed being at least somewhat familiar with cultural humility, and 10 consented to interviews. Strategies for cultural humility education included one-on-one instruction, feedback, and reflections. Thematic analysis underscored fostering learner curiosity about cultures, early patient exposure, and incorporating diverse learning perspectives as essential in developing students' cultural humility skills.</p><p><strong>Conclusion: </strong>Cultural humility is an important attribute for healthcare professionals that can enhance patient-centered care. Through focused interviews with faculty in our study and subsequent thematic analysis, our results suggest the need for longitudinal and multimodal educational strategies to cultivate cultural humility among medical students. By understanding current teaching methods, educators can design and assess more effective curricula to prepare future doctors for a culturally diverse patient population.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241305087"},"PeriodicalIF":0.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11605752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria T Chao, Ariana Thompson-Lastad, Pamela Swedlow, Sudha Prathikanti, Wendy Hartogensis, Folashade Wolfe-Modupe, Jesse Wennik
{"title":"Group-Based Integrative Pain Management in Primary Care: A Study Protocol for Multilevel Interventions to Address Health Disparities.","authors":"Maria T Chao, Ariana Thompson-Lastad, Pamela Swedlow, Sudha Prathikanti, Wendy Hartogensis, Folashade Wolfe-Modupe, Jesse Wennik","doi":"10.1177/27536130241302043","DOIUrl":"10.1177/27536130241302043","url":null,"abstract":"<p><strong>Background: </strong>Socioeconomically disadvantaged populations have a high prevalence of chronic pain, exacerbated by social isolation, intersectional stigma, and disparities in pain assessment and treatment. Effective interventions using a multilevel, biopsychosocial approach are needed to decrease the unequal burden of pain. Group-based integrative pain management in primary care safety net clinics is a promising model to improve pain care for racially and ethnically diverse low-income people.</p><p><strong>Objective: </strong>To describe a study protocol to test the impacts of 2 group-based models - group acupuncture and integrative group medical visits - on multilevel pain-related outcomes.</p><p><strong>Methods: </strong>The study uses a 2x2 factorial randomized clinical trial to test two 12 week group-based models: group acupuncture and integrative group medical visits (IGMV, with psychoeducation, mind-body approaches, and social support). English or Spanish-speaking adults with chronic pain for ≥3 months receiving care in San Francisco Department of Public Health primary care clinics are eligible for the trial. All participants will receive usual care and be randomized to group acupuncture, IGMV, both, or waitlist control. The primary outcomes are changes from baseline to 3 month follow-up in pain impact and in social support for chronic pain. Secondary outcomes include pain interference, pain intensity, depression, anxiety, quality of life, and social isolation. Data will include patient-reported outcomes, electronic health record data, and qualitative interviews, focus groups and observations to assess multilevel individual, interpersonal and organizational outcomes.</p><p><strong>Discussion: </strong>Multilevel approaches are needed to advance health equity in pain management. Our study contributes to knowledge of group-based integrative pain management in primary care safety net clinics to address multilevel barriers and disparities in pain care.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241302043"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michaela Markwart, Donna Felsenstein, Darshan H Mehta, Samreen Sethi, Erika Tsuchiyose, Melis Lydson, Gloria Y Yeh, Daniel L Hall
{"title":"Qigong and Tai Chi for ME/CFS: A Systematic Review of Randomized Controlled Trials.","authors":"Michaela Markwart, Donna Felsenstein, Darshan H Mehta, Samreen Sethi, Erika Tsuchiyose, Melis Lydson, Gloria Y Yeh, Daniel L Hall","doi":"10.1177/27536130241275607","DOIUrl":"10.1177/27536130241275607","url":null,"abstract":"<p><strong>Objective: </strong>Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic and debilitating illness with symptoms such as post-exertional malaise and cognitive dysfunction that can be challenging for patients to manage independently. Randomized controlled trials (RCTs) have examined mind-body and psychological approaches that teach patients coping skills for mitigating ME/CFS symptoms, including emerging literature on Qigong or Tai Chi instruction programs. This systematic review aims to summarize the characteristics of these trials and highlight potential areas for future optimization and refinement.</p><p><strong>Methods: </strong>Ovid MEDLINE, Embase.com, Web of Science Core Collection, Cochrane CENTRAL, PsycINFO via Ovid, and ClinicalTrials.gov were searched in April 2023 using controlled vocabulary and keywords for the following eligibility criteria: Sample (ME/CFS), Design (RCT), Behavioral Intervention (mind-body or psychological interventions). Data extraction and reporting followed Cochrane and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.</p><p><strong>Results: </strong>\"Qigong\" and \"Tai Chi\" yielded 142 and 80 abstracts, respectively. Of the 222 abstracts, full texts were available for 5 RCTs of Qigong (<i>k</i> = 5; N = 481). Notably, no trials of Tai Chi utilized a randomized control design. Among the 5 Qigong RCTs, the publication range was from 2012 to 2023. Details regarding intervention components and effects were summarized. Qigong intervention sessions (median = 12, mode = 10, 12) tended to last between 1-2 hours and occur across 5-12 weeks (median = 7, mode = 5). The Qigong interventions were all delivered in groups and incorporated at-home practice. Daily practice was a requirement (<i>k</i> = 4) or an advisement (<i>k</i> = 1). Patient-reported outcomes suggest an emerging evidence base for diffuse benefits on physical and emotional health outcomes.</p><p><strong>Conclusions: </strong>Qigong interventions are promising, yet relatively understudied, in improving ME/CFS symptom severity and frequency. Future trials must implement standardized eligibility criteria for ME/CFS history, integrate Qigong or Tai Chi with other empirically supported mind-body and psychological practices, and assess long-term resiliency outcomes relevant to ME/CFS survivorship.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241275607"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eunmi Kim, Diane Joss, Frannie Marin, Alessandra Anzolin, Richa Gawande, Alexandra Comeau, Seneca Ellis, Clare Bumpus, B Rael Cahn, Misan W D Kim, Vitaly Napadow, Zev Schuman-Olivier
{"title":"Protocol for a Pilot Study on the Neurocardiac Mechanism of an Interoceptive Compassion-Based Heart-Smile Training for Depression.","authors":"Eunmi Kim, Diane Joss, Frannie Marin, Alessandra Anzolin, Richa Gawande, Alexandra Comeau, Seneca Ellis, Clare Bumpus, B Rael Cahn, Misan W D Kim, Vitaly Napadow, Zev Schuman-Olivier","doi":"10.1177/27536130241299389","DOIUrl":"10.1177/27536130241299389","url":null,"abstract":"<p><strong>Background: </strong>Heart-Smile Training (HST) is an interoceptive compassion-based behavioral intervention that in case reports has been beneficial for depression. Interoception refers to the awareness and regulation of physiological signals from inside the body. Depressed patients often have diminished interoceptive awareness and often experience disconnection from bodily needs and sensations. In addition to interoceptive dysfunction, depression often involves negative self-evaluation and self-critical rumination. HST is a compassion-based meditation training program that explicitly cultivates interoceptive awareness of the heart area. This study aims to investigate the possible neurocardiac mechanisms engaged through HST for depression patients.</p><p><strong>Methods: </strong>We plan to enroll 50 subjects to be randomized into a 4-week HST intervention group and a waitlist group. A battery of psychological questionnaires will be administered at baseline and post-intervention timepoints, and electroencephalography (EEG) will be collected during compassion meditation guided by pre-recorded audio. The primary clinical outcome measures are on the feasibility of the intervention and research procedures, the primary mechanistic outcome measure is the post-intervention change in Heartbeat Evoked Potential (HEP) amplitude. Secondary outcome measures include changes in depression severity and EEG gamma spectral activity. Exploratory outcome measures include effects of HST on skin conductance response, heart rate variability, EEG spectral properties in other frequency bands, as well as a list of psychological questionnaires that measure depression and anxiety symptoms, emotion regulation, mindfulness, interoceptive awareness, self-compassion, gratitude, sleep quality, quality of life and social connectedness.</p><p><strong>Results: </strong>Results not yet available.</p><p><strong>Conclusion: </strong>This is the first study on the feasibility and interoceptive neurocardiac mechanism of HST. Our findings will provide frontier knowledge on the physiological working mechanism of behavioral interventions with an interoception-based meditative approach. https://clinicaltrials.gov/study/NCT05564533.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241299389"},"PeriodicalIF":0.0,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11533199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vanessa Calderón, Ashley Mogul Wyman, Gregg Miller
{"title":"Preliminary Findings From a Pilot Professional Coaching Program on the Components of Burnout in a Diverse Group of Physician Leaders.","authors":"Vanessa Calderón, Ashley Mogul Wyman, Gregg Miller","doi":"10.1177/27536130241296088","DOIUrl":"10.1177/27536130241296088","url":null,"abstract":"<p><strong>Background: </strong>Burnout impacts physicians at alarming rates; physician leaders are not immune. While burnout of physician leaders is associated with decreased leadership efficacy, physician coaching has been associated with reduced burnout.</p><p><strong>Objective: </strong>This study aimed to assess the effect of a physician-leader specific coaching program on the components of burnout.</p><p><strong>Methods: </strong>A 10-week Wellness Coaching Program for physician medical directors was conducted and burnout was measured pre and post intervention using the Maslach Burnout Inventory-General Survey (MBI-GS).</p><p><strong>Results: </strong>All subscales of the MBI-GS trended towards a decrease in the components of burnout with a statistically significant decrease in Cynicism.</p><p><strong>Conclusion: </strong>Wellness coaching programs have the potential to positively impact the threat of burnout experienced by physician leaders in today's health care workforce.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241296088"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contribution of Ethnomedical Use Data to the Marketing Authorization of Traditional Herbal Medicines in Mali.","authors":"Aboubacar Sangho, Kampadilemba Ouoba, Rasmané Semdé, Rokia Sanogo","doi":"10.1177/27536130241296823","DOIUrl":"10.1177/27536130241296823","url":null,"abstract":"<p><strong>Background: </strong>To improve the supply of health care and health care products, traditional herbal medicines that are safe, effective, and of good quality need marketing authorizations. This study aims to determine the contribution of ethnomedical evidence to the marketing of traditional herbal medicines in Mali.</p><p><strong>Methods: </strong>This was a descriptive cross-sectional study conducted from December 2023 to March 2024 supplemented by a literature review of the legislative and regulatory provisions relating to traditional medicine and the requirements for marketing authorization of traditional herbal medicines in Mali and the West African sub-region.</p><p><strong>Results: </strong>The regulatory framework for marketing authorization is governed by decree no. 04-557/P-RM of 01 December 2004 and interministerial order no. 05-2203/MS-MEP-SG of 20 September 2005 in Mali. These texts set out the specific requirements for the marketing authorization of traditional plant-based medicines, depending on the category. They consider ethnomedical evidence drawn from long experience of traditional use as proof of efficacy and tolerance for category 2 traditional medicines. As a result, marketing authorizations were issued for 15 products derived from traditional medicine and pharmacopeia, 5 of which are included in the National List of Essential Medicines and the National Therapeutic Formulary of Mali.</p><p><strong>Conclusion: </strong>The use of ethnomedical evidence provides a good opportunity to obtain marketing authorization for phytomedicines derived from traditional medicine without having to go through long and costly non-clinical and clinical studies.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"13 ","pages":"27536130241296823"},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11503757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}