Global advances in integrative medicine and health最新文献

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Advancing Music Health Research Through Quality Reporting: Introduction to Reporting Guidelines for Music-Based Interventions. 通过质量报告推进音乐健康研究:介绍以音乐为基础的干预报告指南。
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-30 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251384180
Sheri L Robb, Emmeline Edwards
{"title":"Advancing Music Health Research Through Quality Reporting: Introduction to Reporting Guidelines for Music-Based Interventions.","authors":"Sheri L Robb, Emmeline Edwards","doi":"10.1177/27536130251384180","DOIUrl":"10.1177/27536130251384180","url":null,"abstract":"","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251384180"},"PeriodicalIF":1.3,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12579187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reporting Guidelines for Music-Based Interventions: An Update and Validation Study: Secondary publication. 基于音乐的干预报告指南:更新和验证研究:二次出版。
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-30 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251384199
Sheri L Robb, Stacey Springs, Emmeline Edwards, Tasha L Golden, Julene K Johnson, Debra S Burns, Melita Belgrave, Joke Bradt, Christian Gold, Assal Habibi, John R Iversen, Miriam Lense, Jessica A MacLean, Susan M Perkins
{"title":"Reporting Guidelines for Music-Based Interventions: An Update and Validation Study: Secondary publication.","authors":"Sheri L Robb, Stacey Springs, Emmeline Edwards, Tasha L Golden, Julene K Johnson, Debra S Burns, Melita Belgrave, Joke Bradt, Christian Gold, Assal Habibi, John R Iversen, Miriam Lense, Jessica A MacLean, Susan M Perkins","doi":"10.1177/27536130251384199","DOIUrl":"10.1177/27536130251384199","url":null,"abstract":"<p><strong>Background: </strong>Detailed intervention reporting is essential to interpretation, replication, and translation of music-based interventions (MBIs). The 2011 <i>Reporting Guidelines for Music-Based Interventions</i> were developed to improve transparency and reporting quality of published research; however, problems with reporting quality persist. This represents a significant barrier to advances in MBI scientific research and translation of findings to practice.</p><p><strong>Methods: </strong>The purpose of this study was to update and validate the 2011 reporting guidelines using rigorous Delphi approach that involved an interdisciplinary group of MBI researchers; and to develop an explanation and elaboration guidance statement to support dissemination and usage. We followed the methodological framework for developing reporting guidelines recommended by the EQUATOR Network and guidance recommendations for developing health research reporting guidelines. Our three-stage process included: (1) an initial field scan, (2) a consensus process using Delphi surveys (2 rounds) and Expert Panel meetings, and (3) development and dissemination of an explanation and elaboration document.</p><p><strong>Results: </strong>First-Round survey findings revealed that the original checklist items were capturing content that investigators deemed essential to MBI reporting; however, it also revealed problems with item wording and terminology. Subsequent Expert Panel meetings and the Second-Round survey centered on reaching consensus for item language. The revised RG-MBI checklist has a total of 12-items that pertain to 8 different components of MBI interventions including name, theory/scientific rationale, content, interventionist, individual/group, setting, delivery schedule, and treatment fidelity.</p><p><strong>Conclusion: </strong>We recommend that authors, journal editors, and reviewers use the RG-MBI guidelines, in conjunction with methods-based guidelines (eg, CONSORT) to accelerate and improve the scientific rigor of MBI research.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251384199"},"PeriodicalIF":1.3,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12579170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of an Integrated Heartfulness Meditation and Yoga Protocol in Hypertensive Patients: A Randomized Controlled Study. 正念冥想和瑜伽结合治疗高血压的疗效:一项随机对照研究。
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-27 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251388378
Mansee K Thakur, Pooja S Singh, Veronique Nicolai, Mitesh Thakker, Mangesh Pandey, Vidhya S Vijayan
{"title":"Efficacy of an Integrated Heartfulness Meditation and Yoga Protocol in Hypertensive Patients: A Randomized Controlled Study.","authors":"Mansee K Thakur, Pooja S Singh, Veronique Nicolai, Mitesh Thakker, Mangesh Pandey, Vidhya S Vijayan","doi":"10.1177/27536130251388378","DOIUrl":"10.1177/27536130251388378","url":null,"abstract":"<p><strong>Introduction: </strong>Hypertension is increasingly recognized as a biopsychosocial condition influenced by psychological distress and systemic inflammation. The potential of integrative mind-body approaches such as Heartfulness meditation and yoga to offer non-pharmacological benefits through neuroendocrine and immunomodulatory pathways is a source of hope and optimism in the field.</p><p><strong>Objective: </strong>To evaluate the effects of a 12-week Integrated Approach of Heartfulness-based Yogic Practices and Meditation (IAHFNM & YP) on psychological distress, inflammatory cytokines and stress biomarkers in individuals with prehypertension or Stage 1 hypertension.</p><p><strong>Methods: </strong>In this randomized controlled trial participants were allocated to either the intervention group (IAHFNM and YP) or the standard care group. Psychological distress was assessed using the Brief Symptom Inventory-18 (BSI-18). Blood samples were analyzed for cytokines (IL-6, IL-1β, TNF-α, IL-10, IL-18) and neuroendocrine stress markers (copeptin and corticotropin).</p><p><strong>Results: </strong>The intervention group showed significant reductions in psychological distress, including anxiety, depression and somatization, as reflected by a marked decline in the Global Severity Index (<i>P < .001</i>). This reassures us about the study's effectiveness. Inflammatory biomarkers IL-6, IL-1β, and TNF-α significantly decreased (<i>P < .05</i>), while anti-inflammatory IL-10 levels increased (<i>P < .001</i>). Stress-related biomarkers copeptin and corticotropin also showed significant reductions (<i>P < .001</i>), suggesting downregulation of the hypothalamic-pituitary-adrenal (HPA) axis. Although correlations between psychological scores and biomarkers were modest (R<sup>2</sup> < 0.12), corticotropin showed the strongest association with BSI-18 scores (r = 0.389).</p><p><strong>Conclusion: </strong>The findings demonstrate the efficacy of Heartfulness in improving psychological well-being and modulating inflammatory and neuroendocrine markers in prehypertension and hypertension. These results support integrating mind-body practices into hypertension management. However, small sample size, limited duration, and reliance on self-reported adherence may affect generalizability. Future studies with larger cohorts, objective adherence measures, and extended follow-up are recommended to establish sustainability and underlying mechanisms.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251388378"},"PeriodicalIF":1.3,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12575978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CHARacterizing Pediatric Integrative Medicine Within a Large Academic Medical Center (CHARM). 一个大型学术医疗中心(CHARM)的儿科中西医结合特征。
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-25 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251392583
Varun Natarajan, Samuel N Rodgers-Melnick, David W Miller
{"title":"CHARacterizing Pediatric Integrative Medicine Within a Large Academic Medical Center (CHARM).","authors":"Varun Natarajan, Samuel N Rodgers-Melnick, David W Miller","doi":"10.1177/27536130251392583","DOIUrl":"10.1177/27536130251392583","url":null,"abstract":"<p><strong>Background: </strong>Pediatric patients with chronic illnesses face a multitude of health challenges that are often inadequately addressed by conventional, siloed medical systems. Pediatric integrative medicine (PIM), blending complementary therapies with conventional medicine, offers an interdisciplinary and comprehensive approach to addressing these complex challenges. Despite growing demand for PIM, lifestyle-oriented care, and multimodal biopsychosocial interventions, few studies have described the clinical delivery of PIM within a large academic medical center.</p><p><strong>Objectives: </strong>To describe the demographics, clinical characteristics, and interventions utilized within a physician-led, PIM clinic at a large, pediatric academic medical center.</p><p><strong>Methods: </strong>A retrospective review was conducted of 2677 outpatient PIM physician office visits (March 2020-September 2023) among 657 pediatric patients (birth-25 years). Data on demographics, diagnoses, interventions, and supplements were extracted from the electronic health record and summarized using descriptive statistics.</p><p><strong>Results: </strong>Patients (mean age 12.24 ± 5.20 years) were predominantly female (56%) and White (68%). Common conditions included anxiety (59.2%), fatigue (44.4%), headache (43.1%), abdominal pain (33.6%), constipation (33.0%), nausea (31.7%), vitamin D deficiency (30.1%), myofascial pain (29.5%), and depression (26.8%). Key intervention recommendations included dietary changes (61.8%), myofascial self-care interventions (33.8%), massage therapy (21.0%), acupuncture (19.2%), pacing (18.4%), sleep hygiene (18.3%), and exercise (18.1%). Common supplements recommended included probiotics (49.9%), vitamin D (42.6%), multivitamins (41.9%), fish oil (39.4%), magnesium (32.0%), Chinese herbs (29.7%), and melatonin (22.8%).</p><p><strong>Conclusion: </strong>PIM can provide whole-person, integrative care within a large academic medical center for pediatric populations with complex presentations. Its self-governed structure within an academic medical center facilitates broad service integration, addressing demands for comprehensive care. Future practice-based research with standardized documentation and outcome measures is needed to understand PIM's clinical effectiveness.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251392583"},"PeriodicalIF":1.3,"publicationDate":"2025-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12572647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Randomized Trial Testing a Novel Mind and Body Intervention for Depression: Cognitive Behavioral Therapy (CBT) and Whole-Body Hyperthermia (WBH). 一项随机试验测试一种新的心理和身体干预抑郁症:认知行为疗法(CBT)和全身热疗(WBH)。
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-22 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251387714
Ashley E Mason, Wendy Hartogensis, Anoushka Chowdhary, Chelsea J Siwik, Leena S Pandya, Erika Jung, Osnat Lupesko-Persky, Erin Hartley, Lindsey Hopkins, Stefanie Roberts, Jenna Borovinsky, J Craig Nelson, Christopher A Lowry, Rhonda P Patrick, Patricia J Moran, Charles L Raison, Frederick M Hecht
{"title":"A Randomized Trial Testing a Novel Mind and Body Intervention for Depression: Cognitive Behavioral Therapy (CBT) and Whole-Body Hyperthermia (WBH).","authors":"Ashley E Mason, Wendy Hartogensis, Anoushka Chowdhary, Chelsea J Siwik, Leena S Pandya, Erika Jung, Osnat Lupesko-Persky, Erin Hartley, Lindsey Hopkins, Stefanie Roberts, Jenna Borovinsky, J Craig Nelson, Christopher A Lowry, Rhonda P Patrick, Patricia J Moran, Charles L Raison, Frederick M Hecht","doi":"10.1177/27536130251387714","DOIUrl":"10.1177/27536130251387714","url":null,"abstract":"<p><strong>Objective: </strong>To assess the acceptability of a randomized single-blind trial of cognitive behavioral therapy (CBT) and whole-body hyperthermia (WBH) treatment for major depressive disorder (MDD).</p><p><strong>Methods: </strong>All participants (N = 30) with MDD received CBT for depression and were randomized to also receive either: (1) WBH that raised core body temperature using an infrared sauna device, or (2) sham WBH of a similar duration that did not significantly raise core body temperature.</p><p><strong>Results: </strong>Study acceptability was the primary outcome: of participants who completed the final assessment (n = 29; 96.7%), 22 (75.9%) reported that they would recommend participation to a friend or family member with MDD. Twenty-five (86.2%) participants reported that they would be <i>likely</i> or <i>extremely likely</i> to enroll in this study, given the experience they had in the study. All participants randomized to WBH correctly believed they received WBH, and 6 (43%) of participants randomized to sham WBH correctly believed they received sham WBH. Both arms achieved clinically meaningful and statistically significant reductions in depression symptoms. The average decreases in the Beck Depression Inventory-II (BDI-II) were -19.07 (SE = 2.69, <i>P</i> < 0.0001) in the WBH arm (80.0% no longer meeting DSM-5 criteria, 60.0% achieving 50% or greater reduction in BDI-II) and -21.10 (SE = 2.41, <i>P</i><0.0001) in the sham WBH arm (92.9% no longer meeting DSM-5 criteria, 78.6% achieving 50% or greater reduction in BDI-II).</p><p><strong>Conclusions: </strong>Study procedures were acceptable. Participants in the WBH and sham WBH groups had substantial reductions in depressive symptoms that were greater than typically seen with CBT alone. The sham WBH arm was not fully credible and may have exerted antidepressant effects, thus raising concerns about its use in future trials. Further research to test whether adding WBH to CBT results in additional antidepressant effects is warranted.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251387714"},"PeriodicalIF":1.3,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12553885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mindfulness-Based Finger Exercise for Health and Well-Being: Theory, Evidence, and Implications. 基于正念的手指运动对健康和幸福:理论、证据和影响。
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-18 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251386846
Jianghong Liu, Haoer Shi, Yi Yang
{"title":"Mindfulness-Based Finger Exercise for Health and Well-Being: Theory, Evidence, and Implications.","authors":"Jianghong Liu, Haoer Shi, Yi Yang","doi":"10.1177/27536130251386846","DOIUrl":"10.1177/27536130251386846","url":null,"abstract":"<p><strong>Background: </strong>Finger exercise is a mind-body practice rooted in Traditional Chinese Medicine (TCM), grounded in meridian and acupoint theory. It consists of coordinated finger and hand movements, massage, and pressure techniques that stimulate the flow of <i>Qi</i> and improve circulation, strengthen hand-brain connectivity, and cultivate mindfulness. Finger exercise is intended to promote physical health, enhance cognitive function, and support mental well-being.</p><p><strong>Objective: </strong>To introduce the concept of finger exercise, synthesize emerging evidence on its effects on general, physical, cognitive, and mental well-being, and explore potential mechanisms and implications for research and practice. A preliminary framework was developed based on initial evidence.</p><p><strong>Methods: </strong>We conducted a literature search of randominzed controlled trials across three English and two Chinese databases using search terms such as \"finger exercise\" combined with keywords related to health, cognition, depression, anxiety, and sleep. A total of 12 studies published in English or Chinese (with English abstracts) were included in this review.</p><p><strong>Results: </strong>The reviewed studies reported varied intervention protocols incorporating TCM principles, brain-hand coordination, pressure techniques, and mindfulness-based strategies. Preliminary evidence suggests that finger exercise may improve general functioning (eg, ADL/IADL), physical indicators (eg, fatigue, sleep), cognitive performance, and mental health (eg, depression, anxiety). Potential mechanisms include enhanced <i>Qi</i> flow, neuroplasticity, neurotransmitter modulation, reduced inflammation, and improved mindfulness.</p><p><strong>Conclusion: </strong>Mindfulness-based finger exercise shows promise as a low-cost, safe, and easily implemented non-pharmacological intervention that can be done standing or seated and is also suitable for individuals with disabilities or mobility limitations. It has a potential to be integrated into community centers, nursing homes, hospitals, and rehabilitation programs. Further research should confirm its benefits and clarify mechanisms.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251386846"},"PeriodicalIF":1.3,"publicationDate":"2025-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12547132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized Controlled Trial of Acoustic Neuromodulation to Enhance Well-Being in Healthcare Workers. 听神经调节提高医护人员幸福感的随机对照试验。
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-17 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251388984
Catherine L Tegeler, Heidi Munger Clary, Hossam A Shaltout, Gregory B Russell, Suzanne C Danhauer, Charles H Tegeler
{"title":"Randomized Controlled Trial of Acoustic Neuromodulation to Enhance Well-Being in Healthcare Workers.","authors":"Catherine L Tegeler, Heidi Munger Clary, Hossam A Shaltout, Gregory B Russell, Suzanne C Danhauer, Charles H Tegeler","doi":"10.1177/27536130251388984","DOIUrl":"10.1177/27536130251388984","url":null,"abstract":"<p><strong>Background: </strong>Increased stress in healthcare workers (HCW) is a global crisis and few brief, scalable interventions exist to support HCW with stress, anxiety, and insomnia. Individual interventions impacting these multiple symptoms are needed.</p><p><strong>Objective: </strong>To determine whether a noninvasive brainwave echoing acoustic neuromodulation intervention reduces perceived stress among HCW compared to waitlist control.</p><p><strong>Methods: </strong>This was a parallel randomized controlled trial of acoustic neuromodulation vs waitlist control conducted at a large academic health system. Adult HCW with Perceived Stress Scale (PSS) ≥14 were included. Exclusions were factors that would compromise intervention delivery or current engagement with similar interventions. The intervention was a limited dose paradigm of Cereset Research™ Standard Operating Procedures, a noninvasive, closed-loop, brainwave echoing acoustic neuromodulation neurotechnology, composed of four, 36-minute acoustic neuromodulation sessions over 2 weeks. The primary outcome was change in PSS at 6-8 weeks. Secondary outcomes were anxiety (Generalized Anxiety Disorder-7) and insomnia (Insomnia Severity Index). Exploratory outcomes included validated measures of depression, fatigue, and subjective cognition. Group-level changes in outcomes were evaluated using linear mixed models.</p><p><strong>Results: </strong>Of 144 participants (72 per group), 134 completed primary outcome assessment (67 per group). Participants had mean age 44.7 years [SD 11.6] and were 86.1% female (N = 124). Intention-to-treat analyses demonstrated mean PSS score reduction of 7.8 (SD 5.9) in the intervention group vs 1.2 (SD 4.1) among controls (difference between groups 6.6 points, 95% CI 4.9-8.2, <i>P</i> < 0.0001). Secondary and exploratory measures also demonstrated significant group-level improvements in intervention vs control, and there were no serious adverse events.</p><p><strong>Conclusions: </strong>In HCW with elevated stress, acoustic neuromodulation resulted in clinically meaningful improvements in perceived stress, anxiety, and insomnia. The intervention is safe, scalable, and may merit adoption by health systems to complement organization-level approaches for enhancing HCW well-being. Trial Registration: ClinicalTrials.gov, NCT04682197.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251388984"},"PeriodicalIF":1.3,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12541175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145356989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of Hospitalized Patients Referred for Complementary and Integrative Health Services at a Large Metropolitan Academic Medical Center. 大型大都市学术医疗中心补充和综合医疗服务住院患者的特点
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-17 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251388991
Emma M Millon, Andrea Shang, Kathleen A DeMarco
{"title":"Characteristics of Hospitalized Patients Referred for Complementary and Integrative Health Services at a Large Metropolitan Academic Medical Center.","authors":"Emma M Millon, Andrea Shang, Kathleen A DeMarco","doi":"10.1177/27536130251388991","DOIUrl":"10.1177/27536130251388991","url":null,"abstract":"<p><strong>Background: </strong>Complementary and integrative health (CIH) services enhance physiological and psychological wellbeing, while potentially reducing medical costs. Despite these benefits, use of inpatient CIH services remains poorly characterized, impeding efforts to develop equitable and effective healthcare.</p><p><strong>Objective: </strong>This retrospective case-control study examined characteristics of patients likely to receive CIH referrals and consults.</p><p><strong>Method: </strong>Electronic health records were analyzed from patients hospitalized at a large metropolitan academic medical center from September 2022 to February 2024.</p><p><strong>Results: </strong>Referred patients (n = 3491) were less frequently male, Asian American, non-English-speaking, and more medically complex compared to non-referred patients (n = 6982, <i>P</i> values <0.001). Among those referred, 72% received at least one CIH consult, with lower odds of completing a consult for male patients.</p><p><strong>Conclusion: </strong>Disparities underscore the need for equitable CIH services access in healthcare systems. Future research will test how to broaden services to male patients, those with non-English language preference, and less medical complexity, to ensure greater benefit from holistic healthcare.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251388991"},"PeriodicalIF":1.3,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12541185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145355766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ameliorative Effects of Triphala Supplementation on Oxidative Stress and Inflammation in Individuals with Post-COVID-19 Condition: A Preliminary Randomized Controlled Trial. 补充Triphala对covid -19后个体氧化应激和炎症的改善作用:一项初步随机对照试验
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251385551
Suwipa Intakhiao, Nattaphol Prakobkaew, Surachat Buddhisa, Orachorn Boonla, Yothin Teethaisong, Sukrisd Koowattanatianchai, Piyapong Prasertsri
{"title":"Ameliorative Effects of Triphala Supplementation on Oxidative Stress and Inflammation in Individuals with Post-COVID-19 Condition: A Preliminary Randomized Controlled Trial.","authors":"Suwipa Intakhiao, Nattaphol Prakobkaew, Surachat Buddhisa, Orachorn Boonla, Yothin Teethaisong, Sukrisd Koowattanatianchai, Piyapong Prasertsri","doi":"10.1177/27536130251385551","DOIUrl":"10.1177/27536130251385551","url":null,"abstract":"<p><strong>Background: </strong>Triphala, a classical polyherbal formulation in Ayurvedic medicine, has traditionally been used for its diverse therapeutic properties, particularly its antioxidant, anti-inflammatory, and immunomodulatory effects.</p><p><strong>Objective: </strong>This study aimed to evaluate changes in oxidative stress, antioxidant activity, and systemic inflammation following Triphala supplementation in individuals with post-COVID-19 condition.</p><p><strong>Methods: </strong>Seventy-four participants (aged 18-53 years) with a history of COVID-19 were enrolled in a preliminary randomized, double-blind, placebo-controlled trial. Participants were randomly assigned to receive either placebo (n = 37) or Triphala (1000 mg/day; n = 37) capsules, taken 5 days per week for 8 weeks. Biomarkers assessed included malondialdehyde (MDA), protein carbonyl, superoxide dismutase (SOD), interferon-gamma (IFN-γ), and tumor necrosis factor-alpha (TNF-α), measured before and after supplementation.</p><p><strong>Results: </strong>In the Triphala group, MDA (<i>P</i> = 0.026), protein carbonyl (<i>P</i> = 0.017), IFN-γ (<i>P</i> = 0.038), and TNF-α (<i>P</i> < 0.001) levels significantly decreased, while SOD activity increased (<i>P</i> = 0.008). In the placebo group, only SOD activity showed a significant increase (<i>P</i> < 0.001). However, no statistically significant differences were observed between the two groups in any of the primary outcomes.</p><p><strong>Conclusion: </strong>Triphala supplementation may help reduce oxidative stress and systemic inflammation in individuals with post-COVID-19 condition. Future studies with higher doses or longer treatment durations are recommended to confirm and extend these findings.</p>","PeriodicalId":73159,"journal":{"name":"Global advances in integrative medicine and health","volume":"14 ","pages":"27536130251385551"},"PeriodicalIF":1.3,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12536147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Making a Planetary Health Case for Whole Person Health. 为整个人的健康做一个全球健康案例。
IF 1.3
Global advances in integrative medicine and health Pub Date : 2025-10-14 eCollection Date: 2025-01-01 DOI: 10.1177/27536130251388470
Christine Vatovec
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