Frontiers in pain research (Lausanne, Switzerland)最新文献

{"title":"Editorial: Non-biomedical perspectives on pain and its prevention and management - volume II.","authors":"Mark I Johnson, Kate Thompson, Antonio Bonacaro, Emmanouil Georgiadis","doi":"10.3389/fpain.2026.1924013","DOIUrl":"https://doi.org/10.3389/fpain.2026.1924013","url":null,"abstract":"","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1924013"},"PeriodicalIF":2.5,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13481233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Ultrasound-guided dual-target low-temperature plasma ablation for refractory cervicogenic orofacial pain-a report of two cases.","authors":"Juan Liu, Jianxun Li, Yifan Wang, Xianting Chen, Baishan Wu","doi":"10.3389/fpain.2026.1685344","DOIUrl":"https://doi.org/10.3389/fpain.2026.1685344","url":null,"abstract":"<p><strong>Background: </strong>Cervicogenic orofacial pain (COFP) is frequently misdiagnosed or undiagnosed, particularly in patients with refractory orofacial pain. When conventional treatments for conditions such as trigeminal neuralgia, dental pathologies, or oncologic pain fail to provide relief, a cervical spondylotic etiology should be considered. We present two cases of COFP secondary to cervical spondylosis successfully managed with minimally invasive intervention.</p><p><strong>Case presentation: </strong>Both patients present with 3-year histories of unilateral, persistent orofacial pain and dental discomfort. Despite multimodal therapeutic interventions, no significant improvement was observed. Physical examination of the neck and cervical spine MRI both confirmed the diagnosis of cervical spondylosis. After receiving ultrasound-guided low-temperature plasma ablation targeting the C2 dorsal root ganglion and the periarterial region of the vertebral artery V3 segment, both patients experienced immediate and substantial relief from refractory dental and facial pain. Postoperatively, the visual analog scale scores for both patients decreased from 8 to 1. The Jaw Functional Limitation Scale-8 scores improved from 65 to 11 in Patient 1 and from 60 to 8 in Patient 2. Similarly, the Oral Health Impact Profile scores decreased from 45 to 6 in Patient 1 and from 48 to 8 in Patient 2. No recurrence or complications were observed during the 8-month follow-up period.</p><p><strong>Conclusions: </strong>COFP often manifests with subtle symptoms overlapping trigeminal neuralgia and dental disorders, leading to diagnostic delays. Comprehensive neuroanatomical differential diagnosis is critical. Precision-guided minimally invasive cervical interventions can provide effective symptom control, as demonstrated by this dual-target low-temperature plasma ablation approach.</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1685344"},"PeriodicalIF":2.5,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13478172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Warming-dredging acupuncture for cancer-related pain: a systematic review and meta-analysis.","authors":"Jianlong Tu, Qiumei Wu, Jing Wu, Lunling Gan, Jing Xu, Xiaoting Xu","doi":"10.3389/fpain.2026.1870255","DOIUrl":"https://doi.org/10.3389/fpain.2026.1870255","url":null,"abstract":"<p><strong>Background/objectives: </strong>Cancer-related pain (CRP) affects up to 60% of patients during malignancy progression, with many experiencing insufficient relief from pharmacological treatments alone. Warming-dredging acupuncture (WDA) integrates thermal and mechanical stimulation to achieve synergistic analgesic effects. This study aims to evaluate the efficacy, safety, and opioid-sparing potential of WDA in managing CRP.</p><p><strong>Materials and methods: </strong>We searched PubMed/MEDLINE, Embase, CENTRAL, Web of Science, CNKI, VIP, Wanfang Data, SinoMed, and the clinical trial registries (ClinicalTrials.gov and the Chinese Clinical Trial Registry) through March 9, 2026. Only randomized controlled trials (RCTs) were included. We used RevMan 5.4 and Stata 19.0 to analyze data, the RoB 2 tool to assess the risk of bias, and the GRADE system to assess the certainty of the evidence, following the PRISMA 2020 guidelines. The protocol was prospectively registered (PROSPERO: CRD420261335674).</p><p><strong>Results: </strong>Seventeen RCTs involving 1278 participants were included. WDA significantly enhanced pain relief rates (RR = 1.26; 95% CI: 1.19-1.33) and reduced pain scores (MD = -1.05; 95% CI: -1.49 to -0.61) compared to controls. WDA also showed a lower risk of adverse events (RR = 0.35; 95% CI: 0.26-0.46), and evidence suggested a possible reduction trend in analgesic consumption. GRADE certainty ranged from moderate to very low.</p><p><strong>Conclusions: </strong>Warming-dredging acupuncture combined with routine pain management may offer a promising adjunct for multimodal cancer pain management, but the certainty of evidence varied across outcomes.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD420261335674 identifier CRD420261335674.</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1870255"},"PeriodicalIF":2.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13469348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148762854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain in people with dementia is a significant contributor to increased professional caregiver burden: results of an observation study.","authors":"Kreshnik Hoti, Ipsit Vahia, Paola Chivers, Jeffery Hughes","doi":"10.3389/fpain.2026.1868192","DOIUrl":"https://doi.org/10.3389/fpain.2026.1868192","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the association between the presence of neuropsychological symptoms, professional caregiver burden and pain intensity.</p><p><strong>Methods: </strong>Eleven neuropsychiatric symptoms reportedly associated with caregiver burden which are included within the PainChek® pain assessment tool were identified: aggressiveness, inappropriate behavior, distressed, verbally offensive, confusion, restlessness, pacing and wandering, crying, screaming, altered sleep and resisting care. A caregiver burden score based on binary scoring of the presence of these indicators was calculated (summative score range from 0 to 11). Generalized estimating equations were used to evaluate the relationships between (1) pain score and sum of caregiver indicators present and (2) pain (high/low) and caregiver burden indicator presence.</p><p><strong>Results: </strong>The results of 2,125,022 PainChek® assessments completed on 89,230 residents (Average age 84.8 ± 7.7 years, females 62.2%) were evaluated. The binary pain model reported a significant increased risk of high (i.e., moderate or severe) pain (<i>p</i> < 0.001) for all caregiver burden indicators except pacing and wandering (<i>p</i> = 0.494). Being distressed was associated with the highest risk (OR = 12.0) of high pain, followed by altered sleep (OR = 6.0). Age (<i>p</i> = 0.004) and sex (<i>p</i> < 0.001) were both significant confounders, with high pain less likely with increasing age and if a patient was female.</p><p><strong>Conclusions: </strong>Pain associated neuropsychiatric symptoms can contribute to professional caregiver burden and are exacerbated by high pain, emphasizing the need to minimize pain in people living with dementia.</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1868192"},"PeriodicalIF":2.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13468922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148763054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary evidence for central nervous system mechanisms underlying chronic pain perception, modulation, and chronification in adults: a scoping review.","authors":"Annette Willgens","doi":"10.3389/fpain.2026.1806025","DOIUrl":"https://doi.org/10.3389/fpain.2026.1806025","url":null,"abstract":"<p><p>This scoping review used the Joanna Briggs Institute guidelines and the PRISMA extension for Scoping Reviews to support transparent reporting. The eligibility criteria, search strategy, and synthesis were guided by the Population-Concept-Context framework ( 1).</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1806025"},"PeriodicalIF":2.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13469269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Single-access epidural adhesiolysis and catheter-delivered pulsed radiofrequency for refractory failed back surgery syndrome.","authors":"Rafael Nascimento","doi":"10.3389/fpain.2026.1907035","DOIUrl":"https://doi.org/10.3389/fpain.2026.1907035","url":null,"abstract":"<p><p>Failed back surgery syndrome (FBSS) frequently involves mixed mechanical, inflammatory, and neuropathic mechanisms and remains challenging to treat, particularly when systemic anti-inflammatory therapy is limited. We report a 55-year-old woman with chronic refractory left lumbosciatica after endoscopic lumbar discectomy and L3-L4 arthrodesis, with established coronary artery disease and prior myocardial infarction limiting the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Lumbar magnetic resonance imaging demonstrated prior L3-L4 arthrodesis, multilevel degenerative disc disease, and an L4-L5 diffuse disc protrusion causing dural-sac compression, degenerative central canal narrowing, and bilateral foraminal narrowing; lower-limb electroneuromyography did not show active large-fiber radiculopathy. A single-session, single-access caudal procedure was performed using a radiopaque steerable epidural catheter-electrode system, allowing both catheter-directed adhesiolysis and sequential epidural pulsed radiofrequency (PRF) delivery through the catheter tip adjacent to the left S1, L5, L4, and L3 dorsal root ganglion/nerve-root regions. At 5 days, the patient reported approximately 60% improvement in the radiating lower-limb pain. At 8 weeks, she reported approximately 70% improvement in the radicular pain component, while overall pain intensity decreased from NRS 9/10 to 5/10, with residual axial low back pain. A transient sacral neuritis with gluteal paresthesia was the only adverse event and resolved with conservative treatment. This case illustrates a combined interventional strategy for selected patients with refractory FBSS, while the single-case, multicomponent design precludes attribution of benefit to any individual element.</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1907035"},"PeriodicalIF":2.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13469078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148766151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients' experiences of chronic pain and sleep as a vicious circle: a qualitative explorative study from a pain rehabilitation setting.","authors":"Andrea Hållstam, Charlotte Angelhoff, Linda Gellerstedt","doi":"10.3389/fpain.2026.1869706","DOIUrl":"https://doi.org/10.3389/fpain.2026.1869706","url":null,"abstract":"<p><strong>Objective: </strong>Chronic pain and sleep disturbances are common, interrelated conditions that substantially affect quality of life. Patients participating in interdisciplinary chronic pain rehabilitation programs frequently report sleep problems, yet patients' own experiences of sleep within this context remain insufficiently explored. The aim of this study was to describe experiences of sleep and pain among patients with diverse chronic pain conditions who have undergone an interdisciplinary pain rehabilitation program.</p><p><strong>Methods: </strong>An explorative qualitative descriptive design was applied. Data were collected through focus group interviews and individual interviews with patients participating in an interdisciplinary pain rehabilitation program. The data were analysed using reflexive thematic analysis. Reporting followed the Consolidated Criteria for Reporting Qualitative Research (COREQ).</p><p><strong>Results: </strong>The bidirectional relationship between pain and sleep was a central aspect of participants' daily lives. The overarching theme, <i>A vicious circle with two inseparable conditions</i>, reflects how participants experienced pain and sleep disturbances as closely intertwined and difficult to distinguish. Three interconnected themes further described these experiences: <i>Struggling with the interplay between pain and sleep; Striving for balance and meaning in daily life;</i> and <i>Needing understanding, support, and self</i>-<i>compassion</i>. Participants described fragmented sleep, persistent fatigue, and continuous disruption of rest by pain, alongside ongoing efforts to manage everyday life under these conditions. An emotional burden was evident, characterized by self-doubt and questioning the legitimacy of their suffering.</p><p><strong>Conclusion: </strong>The findings illustrate how chronic pain and sleep disturbances coexist in a mutually reinforcing vicious cycle that significantly impacts quality of life. By elucidating the practical, emotional, and social dimensions of these experiences, the study contributes to an extended understanding of chronic pain from a patient perspective. The results underscore the importance of integrating sleep hygiene practices, sleep ergonomics, and holistic, patient-centred approaches within interdisciplinary chronic pain rehabilitation programs.</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1869706"},"PeriodicalIF":2.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13468928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148763617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nerve decompressive surgery of the lower limbs for diabetic peripheral neuropathy: a systematic review and meta-analysis.","authors":"Yufen Zhao, Jiaying Chen, Zirui Li, Yanji Zhang, Mingyuan Tang, Yunxue Zhong, Yang Jian, Chengliang Deng, Zairong Wei","doi":"10.3389/fpain.2026.1879398","DOIUrl":"https://doi.org/10.3389/fpain.2026.1879398","url":null,"abstract":"<p><strong>Objective: </strong>There is no consensus on the efficacy and safety of nerve decompressive surgery of lower limbs (NDSLL) for diabetic peripheral neuropathy (DPN). This systematic review aims to evaluate the efficacy and safety of NDSLL compared with no surgery in DPN by analyzing relevant evidence from randomized controlled trials (RCTs).</p><p><strong>Methods: </strong>Using PubMed, Embase, Cochrane Library, ClinicalTrials.org and Chictr.org.cn, a systemic literature review was performed in accordance with the Preferred Reporting Items for Systemic Reviews and Meta-Analyses statement (CRD42021295459).</p><p><strong>Results: </strong>Screening filtered 793 studies to 7 trials containing 207 patients. Only two of the eight registered RCTs have been published (25% publication rate), indicating substantial publication bias. Risk of bias was high across most trials, with particular concerns regarding: lack of participant and personnel blinding; absence of sham surgery controls in 6/7 trials; incomplete outcome data; and selective reporting. These methodological flaws likely contribute to overestimation of treatment effects. Compared to no surgery, NDSLL was associated with VAS reduction at postoperative month (POM) 6 (WMD: -2.77, 95% CI: -3.84 to -1.69) and POM 12 (WMD: -2.41, 95% CI: -4.52 to -0.29). However, wide confidence intervals-particularly at 12 months-and high bias risk limit confidence in these estimates. No RCT evidence supported improvement in quality of life, nerve conduction velocity, balance, ulcer healing, or sensation. Among 113 NDSLL patients, 27 (23.9%) experienced wound-related complications (infection, dehiscence, edema, hematoma); no complications were reported in no-surgery groups.</p><p><strong>Conclusions: </strong>NDSLL may offer pain relief in selected DPN patients, but the current evidence is derived from a small number of high-bias RCTs with substantial publication bias, considerable methodological heterogeneity, and a notable complication rate. The true treatment effect may be substantially smaller than pooled estimates suggest. The absence of demonstrable benefit on quality of life, nerve function, balance, ulcer healing, or sensation constrains clinical utility. NDSLL should remain an investigational procedure pending adequately powered, sham-controlled, multicenter RCTs with standardized outcome measures. More high-quality research is urgently needed before NDSLL can be recommended as standard treatment.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD42021295459, PROSPERO CRD42021295459.</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1879398"},"PeriodicalIF":2.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13469247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148766023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in rehabilitation for bone and joint pain: a critical narrative review of evidence, gaps, and future directions.","authors":"Jie Zhuang, Jinyan Wang, Yinhu Hu, Juan Jin, Jing Shi, Lei Song, Zekai Hu","doi":"10.3389/fpain.2026.1858635","DOIUrl":"10.3389/fpain.2026.1858635","url":null,"abstract":"<p><p>Chronic bone and joint pain is highly prevalent, and rehabilitation is a core component of care. This critical narrative review uses a transparent, structured evidence-mapping approach to examine rehabilitation studies published from January 2021 to April 2026, integrate findings across intervention classes, and identify evidence gaps. Across the included evidence base, exercise therapy supports pain and functional outcomes in selected musculoskeletal conditions, although optimal dose and phenotype-specific matching remain uncertain. Manual therapy and physical modalities may provide short-term adjunctive symptom relief, but their effects are conditional on technique, context, and protocol. Digital rehabilitation and virtual-reality-based approaches can improve access and engagement, but functional and long-term benefits are heterogeneous. Low-load blood-flow-restriction training is promising where high external loads are not tolerated; safety, dose, and longer-term effectiveness require further study. Rather than implying a universal precision-rehabilitation model, we present phenotype-informed treatment matching as a research agenda. Key limitations include heterogeneity of populations, interventions, outcome measures, and follow-up, the selective nature of narrative synthesis, publication bias, and the absence of pooled quantitative estimates. Exercise remains a foundation of care, with adjuncts selected according to presentation, patient priorities, feasibility, and response to reassessment.</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1858635"},"PeriodicalIF":2.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13468789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148762234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing optimal postoperative pain management: a systematic scoping review.","authors":"Raeesah Fakier, Romy Parker, Mitchell Sarkies, Katleho Limakatso","doi":"10.3389/fpain.2026.1870836","DOIUrl":"10.3389/fpain.2026.1870836","url":null,"abstract":"<p><p>Effective postoperative pain management is a critical component of surgical care, directly influencing patient recovery, satisfaction, and long-term outcomes. Despite recent advances in pain management, postoperative pain remains poorly managed worldwide, suggesting that postoperative pain outcomes are influenced by several factors beyond the inherent efficacy of available treatments. The aim of this scoping review was to map the factors influencing postoperative pain management and to generate interventions that support optimal, evidence-based pain management after surgery. Articles published until September 2025 were identified through a systematic search of the following electronic databases: PubMed (MEDLINE) via EBSCOhost, CINAHL (Cumulative Index to Nursing & Allied Health Literature) via EBSCOhost, and PsycINFO via EBSCOhost. Two reviewers independently conducted the screening of articles and data extraction. Barriers and enablers were synthesized using the Theoretical Domains Framework. Intervention strategies were generated by mapping the identified barriers onto the Capability, Opportunity, Motivation-Behavior model. Patient empowerment and active engagement in pain management, strong clinician-patient rapport, and structured, team-based and policy-driven support were identified as key enablers for optimizing postoperative pain management. On the other hand, a lack of knowledge and misconception about postoperative pain, capability gaps in assessing and managing pain, interprofessional and communication challenges, organizational and policy deficiencies, and resource and workforce constraints were key barriers to optimal postoperative pain management. Despite advancements in treatment options, the findings suggest that optimal pain management requires a multifaceted approach that addresses both individual and systemic challenges. These insights contribute to a deeper understanding of the barriers and enablers of effective pain management and highlight the need for targeted interventions across various levels of healthcare delivery.</p>","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"7 ","pages":"1870836"},"PeriodicalIF":2.5,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13463247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148726062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}