Food safety (Tokyo, Japan)最新文献

{"title":"Subject fields in Food Safety during 10 years.","authors":"Yasushi Yamazoe, Shigeki Yamamoto, Midori Yoshida, Toru Kawanishi, Susumu Kumagai","doi":"10.14252/foodsafetyfscj.D-21-00007","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-21-00007","url":null,"abstract":"Food Safety was started in November 2013 as a scientific journal issued by Food Safety Commission of Japan. (FSCJ) to promote domestic and global communications on food-related sciences. This journal was published quarterly and switched only to electronic publication since the year of 2014. All the issued are listed in J-Stage (https://www. jstage.jst.go.jp/browse/foodsafetyfscj/-char/en) and also the published issues of 2016 or later are listed in PubMed Central. This journal is aiming to cover wide varieties of scientific interests on foods, particularly 1) pathogenesis and toxicity of biological, chemical and physical factors in foods and the related, 2) risk factors in food-chain, 3) controls and epidemiology of food-mediated diseases and 4) foods and food-related items produced through genetic sciences and innovative sciences like nano-materials. Possible changes in trends of subject categories were expected in Food Safety, although relatively short-periods of the publication. A survey was thus conducted to understand interests of the authors and readers on this journal. The survey was divided into two periods before and after a year of 2016. Data were categorized into arbitrarily determined nine-fields. AMR (Antimicrobial-resistant bacteria) is only added in the second period because of the recent introduction. Fields listed are 1) contaminants in foods, 2) food additives, 3) microorganisms and viruses, 4) natural-toxins and mycotoxins, 5) novel foods and genetically modified foods, 6) pharmacology including drug metabolism, 7) prion, 8) risk communication, and 9) toxicology (in alphabetical order). As the results, studies on contaminants in foods and prion shared high rates of the publications, followed by reports on microorganisms and viruses and natural-toxins and mycotoxins, in the first period. Actual numbers of the publications of contaminants in foods and prion were decreased in the second period, probably reflections of calming down of social concerns on BSE and pesticide uses. Reports on microorganisms and viruses and natural-toxins and mycotoxins were in turn increased to share the highest published fields. These increases may be associated with the regulatory alterations. Present survey results indicate no obvious changes in publication fields of Food Safety, although certain extents of fluctuations in the publication ratios are detected. For the ease of readers, individual publication list is noted as follows: List of publication in the first period from No. 1 to 581–58). List of publication in the second period from No. 59 to 15759–160). ©2021 Food Safety Commission, Cabinet Office, Government of Japan doi: 10.14252/foodsafetyfscj.D-21-00007 Food Safety 2021; Vol. 9, No. 2, 25–31","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"9 2","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254849/pdf/foodsafetyfscj-9-25.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial-resistant Bacteria Arising from the Use of Colistin Sulfate in the Livestock (2nd edition) (Antimicrobial-resistant Bacteria).","authors":"","doi":"10.14252/foodsafetyfscj.D-21-00003","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-21-00003","url":null,"abstract":"<p><p>The Food Safety Commission of Japan (FSCJ) updated a risk assessment on antimicrobial-resistant bacteria arising from the use of a veterinary medicinal product, colistin sulfate, in cattle and pigs, according to the \"Assessment Guideline for the Effect of Food on Human Health Regarding Antimicrobial-Resistant Bacteria Selected by Antimicrobial Use in Food-producing Animals\" (FSCJ, September 30, 2004). Both <i>Escherichia coli</i> (<i>E. coli</i>) and <i>Salmonella enterica</i> subsp<i>. enterica</i> (<i>Salmonella</i>) were potential antimicrobial-resistant bacteria. In cases of occurrences of human infectious diseases due to the bacteria in foods derived from livestock, these resistant bacteria could be responsible for reduction or loss of the antibiotic treatment efficacy. FSCJ thus conducted a risk assessment of <i>E. coli</i> and <i>Salmonella</i> as identified hazards. FSCJ judged to be low on the occurrence probability and extent of selection of drug-resistant <i>E. coli</i> and <i>Salmonella</i>, due to the use of colistin sulfate in cattle and pigs, unless otherwise the use of colistin increases. The chance and extent of human exposure to the resistant bacteria were evaluated low via livestock products including pigs and cattle, as long as proper cooking practice is implemented. The degree of possible reduction or loss of clinical effectiveness against <i>E. coli</i> and <i>Salmonella</i> was evaluated as moderate. The overall estimation of the risk regarding reduction or loss of clinical effectiveness of antimicrobials in humans was low. It is necessary to keep up with the latest scientific findings and information.</p>","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"9 1","pages":"22-24"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25536252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering Key Interactions of Ligands with CYP3A4-Template* system.","authors":"Yasushi Yamazoe,&nbsp;Takashi Yamada,&nbsp;Akihiko Hirose,&nbsp;Norie Murayama","doi":"10.14252/foodsafetyfscj.D-20-00023","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-20-00023","url":null,"abstract":"<p><p>Cytochrome P450 (CYP)-mediated metabolisms are often associated with biological and toxicological events of chemicals. A major hepatic enzyme, CYP3A4, showed clear distinctions on their catalyses even among ligands having resemble structures. To better understand mechanisms of their distinct catalyses, possible associations of ligand interactions at specific parts of CYP3A4 residues were investigated using CYP3A4-Template system developed (DMPK 2019 and 2020). A placement was available selectively for CYP3A4-mediated R-thalidomide 5-oxidation on Template, but not for the 5'-oxidation and the S-isomer oxidations. Similar placements were generated for pomalidomide (4-amino-thalidomide), but not for a poor ligand, lenalidomide (3-deoxy-pomalidomide). The latter ligand took placements lacking IJK-Interaction or sticking the 4-amino part beyond the facial-side wall on Template. A placement was available for the <i>tert</i>-butyl oxidation of terfenadine, but not for an analog, ebastine. Their interactions with upper-Cavity-2 residue were expected to differ at their sites of oxygen substituents. Some phenolic antioxidants behave distinctly toward biological oxidations <i>in vitro</i> and <i>in vivo</i>. Butylated hydroxytoluene is oxidized to the peroxy-derivative <i>in vitro</i>, but solely to the oxidized metabolites at the benzyl and <i>tert</i>-butyl methyl positions <i>in vivo</i>. Involvement of CYP3A4 were suggested for all the three reactions from the placements on Template. Tocopherols were also applied on Template for the oxidations for chroman and side-chain terminals. The primary placement was suggested to undergo the futile-recycling through formation of the peroxide intermediate subsequently to lead the substantial lack of the CYP3A4-mediated oxidation. These data suggest the effectiveness of CYP3A4-Template assessment to understand the causal basis of poor oxidations and also to verify the <i>in vivo</i> contribution of CYP3A4-mediated peroxidative reactions.</p>","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"9 1","pages":"10-21"},"PeriodicalIF":0.0,"publicationDate":"2021-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25536251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probabilistic Estimation of Dietary Intake of Methylmercury from Fish in Japan.","authors":"Takahiro Watanabe,&nbsp;Rieko Matsuda,&nbsp;Chikako Uneyama","doi":"10.14252/foodsafetyfscj.D-20-00018","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-20-00018","url":null,"abstract":"Abstract Dietary intake of methylmercury from fish was estimated via Monte Carlo simulation using data for methylmercury concentrations in 210 fish samples and data regarding fish consumption extracted from the Japanese National Health and Nutrition Survey. The fish analyzed were classified into 5 groups according to categories used in the survey. The distribution of consumption of fish from each group was used without fitting to statistical distributions. A log-normal distribution was fitted to the distribution of methylmercury concentration in each fish group. Two random numbers that followed these distributions were generated, and a trial value was calculated by multiplying these random numbers. The trial value was divided by the body weight (50 kg) to arrive at an estimate of dietary methylmercury intake. A total of 100,000 Monte Carlo simulation iterations were performed. The estimated mean daily intake of methylmercury was 0.093 µg/kg body weight (bw)/day. This value is well below the tolerable daily intake of 0.292 µg/kg bw/day calculated from the tolerable weekly intake (2.0 µg/kg bw/week) established by the Food Safety Commission of Japan. The probability that the daily intake of methylmercury exceeds the tolerable daily intake was 7.6%. As there are no data regarding fish consumption for consecutive days, estimation of the weekly intake of methylmercury is a subject for future studies.","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"9 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2021-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25536250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous Estimation of Annual Committed Effective Dose of Radioactive Cesium by Market Basket Study in Japan from 2013 to 2019 after Fukushima Daiichi Nuclear Power Plant Accident.","authors":"Hiromi Nabeshi,&nbsp;Tomoaki Tsutsumi,&nbsp;Masataka Imamura,&nbsp;Yoshinori Uekusa,&nbsp;Akiko Hachisuka,&nbsp;Rieko Matsuda,&nbsp;Reiko Teshima,&nbsp;Hiroshi Akiyama","doi":"10.14252/foodsafetyfscj.D-20-00017","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-20-00017","url":null,"abstract":"<p><p>Radionuclide contamination in foods has been a great concern after the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident. To estimate time trends of daily intake and annual committed effective dose of radionuclides after the accident, radioactive cesium (r-Cs; ¹³⁴Cs and ¹³⁷Cs) and potassium-40 (⁴⁰K) in market basket (MB) samples prepared at 6-month intervals in periods from September 2013 to March 2019 in 15 regions of Japan were analyzed using γ-ray spectrometry. The annual committed effective dose of r-Cs, calculated at non-detected radionuclide levels assumed to be half the limit of detection (LOD), appeared to decrease gradually in 11 regions close to the FDNPP that were more likely to be affected by the accident. Differences in doses among the 15 regions were large just after the accident, but gradually decreased. In particular, ¹³⁴Cs has not been detected in any MB sample in any region since September 2018, and annual committed effective dose from ¹³⁴Cs in all regions was mostly constant at around 0.3 μSv/year (given the respective LODs). The maximum annual committed effective dose of r-Cs in this study was decreased from 2.7 μSv/year in September 2013 to 1.0 μSv/year in March 2019. In contrast, the range of annual committed effective dose of ⁴⁰K varied from approximately 150 to 200 μSv/year during that time frame and did not change much throughout the period of this study. Although annual committed effective doses of r-Cs in regions close to the FDNPP appeared to be higher than in regions far from the FDNPP, doses in all regions are remaining at a much lower levels than the intervention exemption level, 1 mSv/year, in foods in Japan.</p>","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"8 4","pages":"97-114"},"PeriodicalIF":0.0,"publicationDate":"2020-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38791796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attempt of Bayesian Estimation from Left-censored Data Using the Markov Chain Monte Carlo Method: Exploring Cr(VI) Concentrations in Mineral Water Products.","authors":"Yoshinari Suzuki, Noriko Tanaka, Hiroshi Akiyama","doi":"10.14252/foodsafetyfscj.D-20-00007","DOIUrl":"10.14252/foodsafetyfscj.D-20-00007","url":null,"abstract":"<p><p>Hexavalent chromium (Cr(VI)) is toxic, carcinogenic, and mutagenic substances. Oral exposure to Cr(VI) is thought to be primarily from drinking water. However, under the certain reporting limit (~0.1 µg/L), percentage of Cr(VI) concentration in mineral water products under the reporting limit were estimated higher than 50%. Data whose values are below certain limits and thus cannot be accurately determined are known as left-censored. The high censored percentage leads to estimation of Cr(VI) exposure uncertain. It is well known that conventional substitution method often used in food analytical science cause severe bias. To estimate appropriate summary statistics on Cr(VI) concentration in mineral water products, parameter estimation using the Markov chain Monte Carlo (MCMC) method under assumption of a lognormal distribution was performed. Stan, a probabilistic programming language, was used for MCMC. We evaluated the accuracy, coverage probability, and reliability of estimates with MCMC by comparison with other estimation methods (discard nondetects, substituting half of reporting limit, Kaplan-Meier, regression on order statistics, and maximum likelihood estimation) using 1000 randomly generated data subsets (<i>n</i> = 150) with the obtained parameters. The evaluation shows that MCMC is the best estimation method in this context with greater accuracy, coverage probability, and reliability over a censored percentage of 10-90%. The mean concentration, which was estimated with MCMC, was 0.289×10^-3 mg/L and this value was sufficiently lower than the regulated value of 0.05 mg/L stipulated by the Food Sanitation Act.</p>","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"8 4","pages":"67-89"},"PeriodicalIF":0.0,"publicationDate":"2020-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38789894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deoxynivalenol and Nivalenol (2nd edition) [Assuring the Maximum Level of Deoxynivalenol in Wheat] (Natural Toxins and Mycotoxins).","authors":"","doi":"10.14252/foodsafetyfscj.D-20-00031","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-20-00031","url":null,"abstract":"<p><p>Food Safety Commission of Japan (FSCJ) was requested by the Ministry of Health, Labour and Welfare (MHLW) to conduct a risk assessment of deoxynivalenol (DON) to assure the maximal level for DON in foods. Previously, FSCJ had conducted a self-tasking risk assessment of DON and nivalenol (NIV) in 2010. In the current 2nd edition, only the assessment of DON has been revised. Grains contaminated with DON may be also contaminated with its derivatives, namely, 3-acetyldeoxynivalenol (3-Ac-DON), 15-acetyldeoxynivalenol (15-Ac-DON) and deoxynivalenol-3-glucoside (DON-3-glucoside). However, these substances orally ingested are rapidly biotransformed into DON. Therefore, FSCJ identified the total DON (sum of DON and its derivatives) to be assessed. The toxicity of DON was assessed based on the data of absorption-distribution-metabolism-excretion (ADME), acute toxicity, sub-acute toxicity, chronic toxicity, carcinogenicity, reproductive/developmental toxicity, genotoxicity, and immunotoxicity. DON was considered to have no significant genotoxic activity <i>in vivo</i>. The no-observed-adverse-effect level (NOAEL), based on the two-year chronic toxicity study in mice, was set at 0.1 mg DON/kg bw/day. By applying an uncertainty factor (UF) of 100, the TDI for DON was determined as 1 µg /kg bw/day. The average estimated exposure levels of total DON were 0.09 µg /kg bw/day and 0.22 µg/kg bw/day in the whole population and the 1-6 years group, respectively, by the Monte-Carlo method. The average exposure level in Japan was thus judged to be below the TDI, although a chance to exceed the TDI remains possible in the 1-6 years group depending on eating habits and DON contamination. For NIV, the genotoxic property was not able to be assessed due to the limited availability of the experimental data. No carcinogenic effect was observed in a two-year chronic toxicity study in mice, and the International Agency for Research on Cancer (IARC) also classifies <i>Fusarium</i> spp toxins including NIV to be in group 3. FSCJ thus judged that TDI can be set for NIV. Based on various toxicity studies, the TDI of NIV was determined at 0.4 µg/kg bw/day by taking into account of LOAEL 0.4 mg NIV/kg bw/day in a subacute toxicity study in rats with 90-day oral administration and UF of 1,000. The exposure level of NIV in Japan was estimated to be below the TDI. FSCJ judged it's unlikely that NIV intake leads to adverse health effects in general population.</p>","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"8 4","pages":"115-117"},"PeriodicalIF":0.0,"publicationDate":"2020-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38791797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the Risk Perception of Food Safety between 2004 and 2018.","authors":"Aiko Abe,&nbsp;Kazuo Koyama,&nbsp;Chie Uehara,&nbsp;Azusa Hirakawa,&nbsp;Itsuko Horiguchi","doi":"10.14252/foodsafetyfscj.D-20-00015","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-20-00015","url":null,"abstract":"<p><p>To afford the future agenda of risk communication through an evaluation of the past, we examined the changes in risk perception in the food safety sector over the 15 years (2004-2018) since the establishment of the Food Safety Commission of Japan (FSCJ) in 2003 by analyzing the data of the food safety monitor survey. Hazards such as contaminants including cadmium, methylmercury and arsenic, and pesticide residues caused high levels of concern among the public in 2004. In contrast, hazards such as food poisoning by harmful microorganisms and so-called \"Health foods\" have been ranked high among concerns since 2008 and 2014, respectively. Scoring of concern levels showed that concern related to food additives and pesticide residues intentionally added to foods and controlled has gradually decreased in a time-dependent manner. These concern scores were considerably lower in male monitors than in female ones; the scores were also lower for individuals with professional experience in the food sector than without the experience. The concern scores for contaminants were lower for males with professional experience. The concern scores related to food poisoning and health foods were not decreased and were remained high in recent years. These scores did not show clear dependence on job experience or gender of the monitors. A gap between food specialists and other attributes in the basic recognition of risk seems to make it difficult to communicate effectively and constructively among various interested individuals. To improve the quality of risk communication in the food safety field, it will be necessary to provide scientific knowledge and information regarding food safety management mechanisms for individuals without professional experience in the food sector, taking into account the changes in information media and influence on risk perception.</p>","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"8 4","pages":"90-96"},"PeriodicalIF":0.0,"publicationDate":"2020-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38789895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Management Knowledges about Oysters for Raw Consumption and Norovirus.","authors":"Kazuo Koyama, Azusa Hirakawa, Chie Uehara, Itsuko Horiguchi","doi":"10.14252/foodsafetyfscj.D-20-00014","DOIUrl":"10.14252/foodsafetyfscj.D-20-00014","url":null,"abstract":"<p><p>This study used questionnaires to evaluate knowledge levels of risk management of raw-consumption of oysters and of norovirus as health hazards among monitors signed up for Food Safety Commission of Japan (FSCJ) having work experiences in food fields. The mean scores of monitors on norovirus knowledge were relatively high (79%), but on oyster raw-consumption were low (64%). Scores varied depending on occupational experiences; highest among administrative officials, high among researchers in food companies, and low among medical workers and educators. The higher scores with more practical experiences for risk management of oyster raw-consumption and norovirus were observed among the monitors. These monitors were expected better to recognize the risks, wheres only few monitors among the opinion-leaders replied correctly to all the questions. These results suggest the need of improvement on the management system for oyster raw-consumption, from the current complicated to the more precise and reinforced for consumers. To efficiently manage the risk associated with the consumption of raw oysters, the government should provide more relevant information of risk management to persons having interest, particularly influencers, in order to disseminate information and to improve knowledge among cooks and consumers.</p>","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"8 3","pages":"59-63"},"PeriodicalIF":0.0,"publicationDate":"2020-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38545999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cattle Meat and Offal Imported from the United States of America, Canada and Ireland to Japan (Prions).","authors":"","doi":"10.14252/foodsafetyfscj.D-20-00019","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-20-00019","url":null,"abstract":"<p><p>Food Safety Commission of Japan (FSCJ) was requested by the Ministry of Health, Labour and Welfare (MHLW) to conduct a risk assessment of cattle meat and offal imported from the United States of America (U.S.A.), Canada and Ireland. FSCJ assessed potential influences on bovine spongiform encephalopathy (BSE) risks to human health in cases of the alteration of cattle age to be allowed to import of cattle meat and offal from the three countries, from the current under 30 months of age to no age limitation, in line with the international standards for mitigating BSE risks. FSCJ judges that the control measures regarding \"risks related to slaughtering and meat processing\" are appropriately implemented in the three countries. FSCJ concludes that potential variations of BSE risks to human health by removing the age limit on cattle meat and offal excluding specified risk material (SRMs) imported from the three countries in line with the international standards is negligible.</p>","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"8 3","pages":"64-65"},"PeriodicalIF":0.0,"publicationDate":"2020-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38546000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}