Food safety (Tokyo, Japan)最新文献

Importance of Global Genomic Data Sharing to Prevent Illnesses Linked to Commercially Distributed Foods. 全球基因组数据共享对预防与商业分销食品有关的疾病的重要性。

Food safety (Tokyo, Japan) Pub Date : 2025-09-26 eCollection Date: 2025-09-01 DOI: 10.14252/foodsafetyfscj.D-25-00003

Matthew E Wise, Christine C Lee, Laura Gieraltowski, Thai-An Nguyen, Megin Nichols, Morgan N Schroeder, Heather A Carleton

{"title":"Importance of Global Genomic Data Sharing to Prevent Illnesses Linked to Commercially Distributed Foods.","authors":"Matthew E Wise, Christine C Lee, Laura Gieraltowski, Thai-An Nguyen, Megin Nichols, Morgan N Schroeder, Heather A Carleton","doi":"10.14252/foodsafetyfscj.D-25-00003","DOIUrl":"10.14252/foodsafetyfscj.D-25-00003","url":null,"abstract":"Changes in food production and distribution, including global distribution of foods, have affected the types of foodborne disease outbreaks that occur. As a result, outbreaks are frequently identified that cause illnesses affecting people across wide geographic regions. Pathogen subtyping is the most effective way to detect these outbreaks, by grouping together cases of foodborne illness that likely share a common source. Over the last decade, the use of whole genome sequencing-based subtyping methods for foodborne bacteria has rapidly expanded. These methods not only provide a much higher resolution view of the bacterial genome, but also open the door to improved sharing of genomic data internationally. We describe four recent outbreak investigations linked to globally distributed foods and other products in which international genomic data sharing played a key role in the investigation: a listeriosis outbreak linked to enoki mushrooms and three different salmonellosis outbreaks linked to onions, sesame paste, and small turtles. Although there are technical and cost barriers to expanding the use of whole genome sequencing and other high-resolution subtyping methods, advancements and accessibility in using these technologies are creating novel opportunities for widespread global implementation so that international collaborations can detect, investigate, and stop outbreaks and reduce the impact of foodborne illnesses globally.","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"13 3","pages":"56-61"},"PeriodicalIF":0.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Targeting Mitochondria to Inhibit Aflatoxin Production: Mechanistic Insight. 靶向线粒体抑制黄曲霉毒素的产生：机制的洞察。

Food safety (Tokyo, Japan) Pub Date : 2025-09-26 eCollection Date: 2025-09-01 DOI: 10.14252/foodsafetyfscj.D-25-00001

Tomohiro Furukawa, Masayo Kushiro, Hiroyuki Nakagawa, Shohei Sakuda

引用次数: 0

Characteristics of Outbreaks Caused by Clostridium Perfringens in Japan. 日本产气荚膜梭菌爆发的特点。

Food safety (Tokyo, Japan) Pub Date : 2025-09-26 eCollection Date: 2025-09-01 DOI: 10.14252/foodsafetyfscj.D-24-00020

Takahiro Ohnishi

引用次数: 0

Anisakis Contamination in Fillets of Chub Mackerel and Blue Mackerel Sold in Japan. 在日本出售的鲐鱼及青花鱼鱼片含异尖藻。

Food safety (Tokyo, Japan) Pub Date : 2025-09-26 eCollection Date: 2025-09-01 DOI: 10.14252/foodsafetyfscj.D-25-00022

Takahiro Ohnishi, Reiko Teshima, Hiromu Sugiyama

引用次数: 0

On the Symposium "Concept of Integrated Approaches to Testing and Assessment (IATA) Using New Approach Methods (NAMs) -Learning from the Study of Thyroid Hormone System and Developmental Neurotoxicity-". 在“使用新方法（NAMs）的综合测试和评估方法（IATA）的概念-从甲状腺激素系统和发育神经毒性研究中学习-”研讨会上。

Food safety (Tokyo, Japan) Pub Date : 2025-09-26 eCollection Date: 2025-09-01 DOI: 10.14252/foodsafetyfscj.D-25-00024

Shigeki Yamamoto, Satoshi Asano, Tomotaka Sobue, Masahiro Tohkin

{"title":"On the Symposium \"Concept of Integrated Approaches to Testing and Assessment (IATA) Using New Approach Methods (NAMs) -Learning from the Study of Thyroid Hormone System and Developmental Neurotoxicity-\".","authors":"Shigeki Yamamoto, Satoshi Asano, Tomotaka Sobue, Masahiro Tohkin","doi":"10.14252/foodsafetyfscj.D-25-00024","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-25-00024","url":null,"abstract":"Food Safety Commission of Japan (FSCJ) hosted a symposium entitled \"Concept of Integrated Approaches to Testing and Assessment (IATA) Using New Approach Methods (NAMs) -Learning from the Study of Thyroid Hormone System and Developmental Neurotoxicity-\" to deepen our understanding on the application of NAMs through practical examples. The symposium took place at FSCJ meeting room (Akasaka, Minato-ku, Tokyo) on December 5th, 2024, attracting a total of 21 on-site attendees as well as 153 online participants. FSCJ Chairperson Dr. YAMAMOTO gave an opening remark. In the presentation 1, Dr. AKAHORI Yumi from the Chemicals Evaluation and Research Institute, Japan (CERI), who also serves as a member of FSCJ's Working Group on Assessment Methodology Development, presented a lecture titled \"International Activities Related to NAMs.\" In the presentation 2, Dr. Mary Gilbert from the US EPA gave a lecture titled \"Thyroid Disruption and Neurodevelopment in an Adverse Outcome Framework Translating NAMs- Filling in Gaps.\" In the Q&A session, participants discussed about the concept and definition of NAMs. In concluding the seminar, Dr. ASANO remarked that, given the active efforts to leverage NAMs abroad led by Europe and the US, FSCJ will continue to discuss various NAMs which would be accumulated internationally and their potential applications.","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"13 3","pages":"65-67"},"PeriodicalIF":0.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serine Utilization by Campylobacter Jejuni and Campylobacter Coli. 空肠弯曲菌和大肠弯曲菌对丝氨酸的利用。

Food safety (Tokyo, Japan) Pub Date : 2025-09-12 eCollection Date: 2025-09-01 DOI: 10.14252/foodsafetyfscj.D-25-00004

Ayako Watanabe-Yanai, Taketoshi Iwata, Yukino Tamamura-Andoh, Nobuo Arai, Anna Momoki, Masahiro Kusumoto

{"title":"Serine Utilization by Campylobacter Jejuni and Campylobacter Coli.","authors":"Ayako Watanabe-Yanai, Taketoshi Iwata, Yukino Tamamura-Andoh, Nobuo Arai, Anna Momoki, Masahiro Kusumoto","doi":"10.14252/foodsafetyfscj.D-25-00004","DOIUrl":"10.14252/foodsafetyfscj.D-25-00004","url":null,"abstract":"The intestinal pathogens Campylobacter jejuni and Campylobacter coli are the most common causes of foodborne bacterial gastroenteritis in humans. In Japan and globally, more than 90% of Campylobacter species isolated from patients with Campylobacter food poisoning are C. jejuni, whereas C. coli accounts for only a small percentage. This difference in isolation rates is considered to be due to differences in the ability of C. jejuni and C. coli to proliferate within the host. However, only a few studies have compared the growth of these two pathogens. To investigate the effect of C. jejuni on the proliferative ability of C. coli and vice versa, co-culture experiments were conducted. Similar strains were selected on the basis of their amino acid requirements for comparative purposes. C. jejuni grew on amino acid-rich media, indicating that its growth was not affected by the presence of C. coli. By contrast, the growth of C. coli was inhibited by C. jejuni. This suggests that the higher detection rate of C. jejuni may be due to its superior growth capacity rather than its initial abundance. Further research on C. coli is required to better understand its role and behavior in the host and in different environments.","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"13 3","pages":"38-42"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cashew Nut Shell Liquid (CNSL) (Feeds, Fertilizers, etc.). 腰果壳液（CNSL）（饲料、肥料等）。

Food safety (Tokyo, Japan) Pub Date : 2025-06-28 eCollection Date: 2025-06-01 DOI: 10.14252/foodsafetyfscj.D-25-00020

引用次数: 0

Anacardic Acid (Exempted Substances*¹) (Feeds, Fertilizers, etc.). 无心酸（豁免物质*1）（饲料、肥料等）。

Food safety (Tokyo, Japan) Pub Date : 2025-06-27 eCollection Date: 2025-06-01 DOI: 10.14252/foodsafetyfscj.D-25-00019

{"title":"Anacardic Acid (Exempted Substances*1) (Feeds, Fertilizers, etc.).","authors":"","doi":"10.14252/foodsafetyfscj.D-25-00019","DOIUrl":"https://doi.org/10.14252/foodsafetyfscj.D-25-00019","url":null,"abstract":"Food Safety Commission of Japan (FSCJ) conducted a risk assessment of anacardic acid (CAS No. 11034-77-8) in response to the request from the Ministry of Health, Labour and Welfare (MHLW) in line with the application for a new designation of cashew nutshell liquid (CNSL) as a feed additive. Anacardic acid, a major substance of CNSL, is an alkyl phenol suppressing methane production in the first rumen of cattle. Submitted documents for the feed additive designation was used for the current evaluation. The data used in the assessment include fate in animals (cattle and others), tissue residues (cattle), genotoxicity, acute toxicity (mice), and subacute toxicity (mice). FSCJ determined the non-observed-adverse-effect level (NOAEL) of 600 mg/kg bw per day for the females and 1,000 mg/kg bw per day (the maximum dose) for the males. Although chronic toxicity and carcinogenicity studies for anacardic acid have not conducted, possible concerns of chronic effects would be anticipated from the results of the subacute toxicity study, and also considering the low residue of anacardic acid and the long-term food experience of cashew nuts containing the anacardic acid. In Japan, CNSL containing anacardic acid has been applied as a feed ingredient to livestock since 2012. No safety issue has been reported on livestock or their products due to this feed ingredient. FSCJ concluded that anacardic acid would not harm human health through the residues in food as long as used ordinally as a feed additive.","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"13 2","pages":"34-35"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12214203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pentoxazone (Second Edition) (Pesticides). 戊氧唑酮（第二版）（农药）。

Food safety (Tokyo, Japan) Pub Date : 2025-06-27 eCollection Date: 2025-06-01 DOI: 10.14252/foodsafetyfscj.D-25-00014

引用次数: 0

Detection of Single Cell Contamination of Salmonella in Foods by SALX System and NIHSJ-01 and Estimation of LOD₉₅. SALX系统和NIHSJ-01检测食品中沙门氏菌单细胞污染及LOD95的估计

Food safety (Tokyo, Japan) Pub Date : 2025-06-27 eCollection Date: 2025-06-01 DOI: 10.14252/foodsafetyfscj.D-25-00008

Hideaki Matsuoka, Takatoshi Moriyama, Natsuko Koshimizu, Norimasa Takatani, Tomonori Yoshida, Yoshiomi Shimabara, Tomoe Hirai, Kazuhide Nakajima, Shizunobu Igimi, Mikako Saito

{"title":"Detection of Single Cell Contamination of Salmonella in Foods by SALX System and NIHSJ-01 and Estimation of LOD95.","authors":"Hideaki Matsuoka, Takatoshi Moriyama, Natsuko Koshimizu, Norimasa Takatani, Tomonori Yoshida, Yoshiomi Shimabara, Tomoe Hirai, Kazuhide Nakajima, Shizunobu Igimi, Mikako Saito","doi":"10.14252/foodsafetyfscj.D-25-00008","DOIUrl":"10.14252/foodsafetyfscj.D-25-00008","url":null,"abstract":"A novel idea of statistical analytical procedure for the level of detection (LOD) was demonstrated by its successful application to qualitative test methods for Salmonella, SALX System and NIHSJ-01. Salmonella cells of a hydrogen sulfide-producing strain FSD287 and a non-hydrogen sulfide-producing strain FSD347 were added to beef and shrimp food samples using a cell sorter to achieve bacterial cell concentration of 1, 5, and 10 cfu/25g-test portion (tp). The colony forming probability (CFP) of the added cells was estimated by means of 10×10 sorting plates. All of test portions containing FSD287 or FSD347 were decided to be positive by SALX System. NIHSJ-01 using CHROMagar® Salmonella (CHS) decided test portions of each of both strains to be positive, while NIHSJ-01 using desoxycholate hydrogen sulfide lactose (DHL) agar decided selectively only FSD287-test portions to be positive. All blank test portions were negative. To evaluate the level of detection at 95% probability (LOD95), in addition to test results, we introduced virtual results of blank conditions approaching zero. As a result, LOD95 for every case was estimated to be lower than 0.326 cfu/tp indicating that both methods were able to detect 1 cfu/tp at higher than 95% probability. Therefore, our protocol for statistical analysis for LOD was feasible for the verification of the test methods that meet the requirement of detecting small number (minimum 1 cfu/25g-tp) of target micro-organisms in food test portions.","PeriodicalId":73044,"journal":{"name":"Food safety (Tokyo, Japan)","volume":"13 2","pages":"23-31"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12214205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0