Exploratory research in clinical and social pharmacy最新文献

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Understanding pharmacists' engagement in sport and exercise medicine, including pharmacist-physiotherapist collaboration: A qualitative study and COM-B analysis. 了解药剂师参与运动和运动医学,包括药剂师-物理治疗师合作:一项定性研究和COM-B分析。
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-20 DOI: 10.1016/j.rcsop.2025.100593
Alison D. Hooper , Jodie Marquez , Beata Bajorek , Joyce Cooper , David Newby
{"title":"Understanding pharmacists' engagement in sport and exercise medicine, including pharmacist-physiotherapist collaboration: A qualitative study and COM-B analysis.","authors":"Alison D. Hooper ,&nbsp;Jodie Marquez ,&nbsp;Beata Bajorek ,&nbsp;Joyce Cooper ,&nbsp;David Newby","doi":"10.1016/j.rcsop.2025.100593","DOIUrl":"10.1016/j.rcsop.2025.100593","url":null,"abstract":"<div><h3>Background</h3><div>Sport and exercise medicine (SEM) is a multidisciplinary field that integrates expertise from various healthcare professionals to optimise athletic performance and promote physical activity for chronic disease prevention and management. Australian pharmacists are well-positioned to contribute to SEM, yet their roles remain undefined beyond niche areas like anti-doping. Interdisciplinary collaboration, particularly with physiotherapists, is also underexplored. This study investigates pharmacists' engagement in SEM and pharmacist-physiotherapist collaboration, using the Capability, Opportunity, Motivation–Behaviour (COM<img>B) model to explore behavioural components.</div></div><div><h3>Methods</h3><div>A qualitative study was conducted using semi-structured interviews with 14 Australian pharmacists practicing across diverse settings. Data were thematically analysed and mapped to the COM-B framework.</div></div><div><h3>Results</h3><div>Five key themes emerged: (1) Broad scope of pharmacy practice in SEM incorporating both pharmacological and non-pharmacological advice; (2) Opportunities and challenges in inter-professional collaboration, constrained by informal referral pathways and limited interdisciplinary communication (3) Gaps in SEM-related training and education, with pharmacists expressing interest in targeted professional development; (4) Perceived barriers to engagement, including time constraints, remuneration issues and lack of professional recognition; and (5) Future opportunities for pharmacists in SEM, such as integration into multidisciplinary SEM teams and supporting physiotherapist prescribing.</div></div><div><h3>Conclusions</h3><div>Pharmacists are well-placed to play a broader role in SEM but face systemic and educational barriers. Enhancing training, establishing formal referral and interdisciplinary communication pathways and addressing structural challenges could improve engagement. This study lays the groundwork for future interventions to enhance pharmacists' contributions to SEM and strengthen pharmacist-physiotherapist collaboration, ultimately improving consumer care and health outcomes.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100593"},"PeriodicalIF":1.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Employing bibliometrics and natural language processing (NLP) to analyse real-world applications of adverse drug reaction 采用文献计量学和自然语言处理(NLP)来分析药物不良反应的实际应用
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-17 DOI: 10.1016/j.rcsop.2025.100592
Viola Savy Dsouza , Lada Leyens , Angela Brand
{"title":"Employing bibliometrics and natural language processing (NLP) to analyse real-world applications of adverse drug reaction","authors":"Viola Savy Dsouza ,&nbsp;Lada Leyens ,&nbsp;Angela Brand","doi":"10.1016/j.rcsop.2025.100592","DOIUrl":"10.1016/j.rcsop.2025.100592","url":null,"abstract":"<div><h3>Introduction</h3><div>Adverse Drug Reactions (ADRs) pose significant health and economic burdens, yet underreporting and inconsistent standards persist. Digital health innovations, particularly mobile and web-based ADR reporting applications, offer potential to enhance pharmacovigilance by improving data accuracy and patient-reported outcomes.</div></div><div><h3>Objectives</h3><div>The study provides a comprehensive mapping of ADR mobile and web application literature, analysing publication trends, key contributors, and core themes through bibliometric and NLP-based content analysis.</div></div><div><h3>Methods</h3><div>A systematic two-stage approach was applied to 289 Web of Science articles on ADR reporting applications. Bibliometric analysis explored publication trends, co-authorship networks, and keyword occurrences, while NLP-based topic modelling identified prevalent themes, ensuring thematic coherence and interpretability.</div></div><div><h3>Results</h3><div>Bibliometric analysis showed a rise in ADR application-related publications, primarily from the United Kingdom, United States of America, and Switzerland. Content analysis identified ten key themes, including pharmacovigilance, chemotherapy adherence, and psychiatry research. A distinct focus on digital tools in ADR reporting and management was evident, with keywords such as “mobile,” “application,” and “patient” becoming increasingly prominent in recent years. Co-authorship and collaboration networks, however, showed limited cross-national research partnerships.</div></div><div><h3>Discussion</h3><div>The study highlights the transformative role of digital solutions in pharmacovigilance, demonstrating the potential of ADR applications to enhance reporting accuracy and improve patient safety. However, adoption remains early-stage and fragmented by regional affiliations. Future research should focus on patient-centric app development, effectiveness assessment, and fostering global collaboration. Strengthening digital literacy and robust investment in ADR reporting applications is crucial for optimizing their impact in healthcare.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100592"},"PeriodicalIF":1.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prevalence of clinically relevant herb-drug interactions between herbal products and anti-cancer therapy in older adults with cancer – A cross-sectional study 中草药产品与老年癌症患者抗癌治疗之间临床相关中草药相互作用的流行-一项横断面研究
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-17 DOI: 10.1016/j.rcsop.2025.100585
Edwin J. Brokaar , Frederiek van den Bos , Johanneke E.A. Portielje , Loes E. Visser
{"title":"The prevalence of clinically relevant herb-drug interactions between herbal products and anti-cancer therapy in older adults with cancer – A cross-sectional study","authors":"Edwin J. Brokaar ,&nbsp;Frederiek van den Bos ,&nbsp;Johanneke E.A. Portielje ,&nbsp;Loes E. Visser","doi":"10.1016/j.rcsop.2025.100585","DOIUrl":"10.1016/j.rcsop.2025.100585","url":null,"abstract":"<div><h3>Background</h3><div>The use of herbal supplements is highly prevalent amongst people with cancer and may lead to clinically relevant herb-drug interactions (HDIs) with their anti-cancer treatment. As the number of older adults with cancer increases, the numbers of older adults with cancer that are at risk of a HDI with anti-cancer treatment increases as well.</div></div><div><h3>Objective</h3><div>The goal of this study was to establish the prevalence of potentially relevant HDIs in older adults who undergo anti-cancer treatment. Also, the overall use of herbal products in this population and possible associations with patient characteristics were investigated.</div></div><div><h3>Method</h3><div>In this single center cross-sectional study patients aged ≥65 years were invited to participate if they underwent systemic anticancer treatment for a solid or hematological cancer. A questionnaire was developed to investigate the use of a selected set of frequently used herbs with known HDIs with regular medications. If a selected herb was used, the herb and oncological medication were assessed for potentially relevant HDIs. All potentially relevant HDIs were independently evaluated by two pharmacists on clinical relevance.</div></div><div><h3>Results</h3><div>A total of 202 patients were included in the analysis. The mean age was 74 years and 54 % was male. The prevalence of potentially relevant HDIs was 4 % and overall herb use was 12 %. Thirteen potentially relevant HDIs were identified, of which 6 were judged to be clinically relevant. The clinically relevant HDIs concerned red yeast rice, red coneflower, turmeric, and cannabis. None of the patient characteristics were associated with overall herb use.</div></div><div><h3>Conclusion</h3><div>Potentially relevant HDIs between herbal supplements and oncological treatment occur in 4 % of older adults with cancer and half of these are clinically relevant. Healthcare providers should question patients with cancer on the use of herbal supplements and monitor for relevant HDI with the treatment given.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100585"},"PeriodicalIF":1.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic dispensing without a prescription across community pharmacies: A simulated patient study 在社区药房无处方分发抗生素:一项模拟患者研究
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-13 DOI: 10.1016/j.rcsop.2025.100590
Thu Anh Do , Phuong Bao Quan , Thy Tran-Bao Le , Tuyen Thanh Du , Suong Thi-Thanh Duong , Kim Thai-Thien Nguyen , Khoi Ngoc Nguyen , Hoa Quoc Nguyen
{"title":"Antibiotic dispensing without a prescription across community pharmacies: A simulated patient study","authors":"Thu Anh Do ,&nbsp;Phuong Bao Quan ,&nbsp;Thy Tran-Bao Le ,&nbsp;Tuyen Thanh Du ,&nbsp;Suong Thi-Thanh Duong ,&nbsp;Kim Thai-Thien Nguyen ,&nbsp;Khoi Ngoc Nguyen ,&nbsp;Hoa Quoc Nguyen","doi":"10.1016/j.rcsop.2025.100590","DOIUrl":"10.1016/j.rcsop.2025.100590","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the proportion of antibiotics dispensed, counseling content, and factors associated with antibiotic dispensing for patients with common cold symptoms among community pharmacists (CPs) in Ho Chi Minh City (HCMC).</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from January to June 2023 using a simulated patient (SP) method. A total of 352 community pharmacies across 24 districts in HCMC were randomly selected. The SP provided complaints including having fever, sore throat, cough, swallowing difficulty, stuffy nose and asked for treatment. Bayesian Model Averaging was undertaken to determine the factors associated with antibiotic dispensing practices.</div></div><div><h3>Results</h3><div>Of 352 enrolled pharmacies, the proportions of antibiotics suggested and eventually dispensed by CPs were 86.4 % and 83.0 %, respectively. Antipyretics, corticosteroids, and cough medicines were also frequently dispensed (94.9 %, 90.1 %, and 85.8 %, respectively). Only 1.7 % of the CPs provided reasons to take antibiotics, and 8.8 % advised to take the full course of antibiotics. While 80.1 % of CPs counseled on the dosage of medications dispensed, 1.7 % provided information regarding potential drug adverse reactions. CPs at chain pharmacies and in urban areas were less likely to dispense antibiotics without a prescription than their peers at independent pharmacies (OR = 0.32; 95 % CI: 0.17–0.59) and in rural areas (OR = 0.53, 95 % CI: 0.29–0.97).</div></div><div><h3>Conclusion</h3><div>A high proportion of CPs dispensing antibiotics without a prescription along with inadequate counseling content, especially at independent pharmacies and in rural areas was recorded. These issues hightlight the need to improve CPs' knowledge regarding antibiotic resistance and appropriate antibiotic use.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100590"},"PeriodicalIF":1.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing personas to examine older adult engagement with televised direct-to-consumer advertisements: A theory based approach 发展人物角色来研究老年人对电视直接面向消费者的广告的参与:一种基于理论的方法
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-13 DOI: 10.1016/j.rcsop.2025.100589
Emily L. Hoffins MS , Taylor L. Watterson PharmD, PhD , Michelle A. Chui PharmD, PhD
{"title":"Developing personas to examine older adult engagement with televised direct-to-consumer advertisements: A theory based approach","authors":"Emily L. Hoffins MS ,&nbsp;Taylor L. Watterson PharmD, PhD ,&nbsp;Michelle A. Chui PharmD, PhD","doi":"10.1016/j.rcsop.2025.100589","DOIUrl":"10.1016/j.rcsop.2025.100589","url":null,"abstract":"<div><h3>Background</h3><div>The average adult in the United States views up to 16 h of direct-to-consumer television advertisements (DTCA) per year, far exceeding time they spend with their primary care team. DTCAs present a unique opportunity to extend medical education beyond traditional medical settings and into the daily lives of patients. This is particularly valuable for populations with changing healthcare needs, such as older adults. As pharmaceutical companies invest in DTCAs, there is a growing need to identify what characteristics make viewers more likely to retain and act on medication information presented in DTCAs.</div></div><div><h3>Objective</h3><div>This paper presents a theory based approach to developing personas of older adult DTCA viewers that categorize characteristics influencing their approach to healthcare engagement.</div></div><div><h3>Methods</h3><div>In 2023, 25 older adult participants watched a one minute DTCA followed by a semi-structured interview. The interview guide applied concepts from the human factors engineering Communication-Human Information Processing model (C-HIP). C-HIP provided structure for both identifying personal characteristics that influence cognition and examining how these factors influence older adult's ability and desire to retain information from DTCAs. Personas were iteratively developed using qualitative analysis.</div></div><div><h3>Results</h3><div>The study yielded three main older adult DTCA viewing personas. These include: 1) medication averse older adults who actively avoid taking medications, 2) information seeking older adults who independently research health information to participate in shared-decision making, and 3) medication adhering older adults who prefer their provider to control decisions.</div></div><div><h3>Conclusion</h3><div>Constructing older adult personas provides insights into the heterogeneity among older adult approaches to engaging with health information. Each persona represents unique information priorities and personal characteristics of older adults when viewing advertisements, thus presenting a need for tailored patient-centered messaging in commercials.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100589"},"PeriodicalIF":1.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the pharmacist's role in regional, rural, and remote kidney transplant care: Perspectives of health professionals and transplant recipients 探索药剂师在地区、农村和偏远地区肾移植护理中的作用:卫生专业人员和移植受者的观点
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-11 DOI: 10.1016/j.rcsop.2025.100587
Tara K. Watters , Nicole J. Scholes-Robertson , Andrew J. Mallett , Beverley D. Glass
{"title":"Exploring the pharmacist's role in regional, rural, and remote kidney transplant care: Perspectives of health professionals and transplant recipients","authors":"Tara K. Watters ,&nbsp;Nicole J. Scholes-Robertson ,&nbsp;Andrew J. Mallett ,&nbsp;Beverley D. Glass","doi":"10.1016/j.rcsop.2025.100587","DOIUrl":"10.1016/j.rcsop.2025.100587","url":null,"abstract":"<div><h3>Background</h3><div>Role clarification amongst health professionals is necessary for successful interprofessional collaboration. Despite a demonstrated need for pharmacists in the provision of care to regional, rural, and remote kidney transplant recipients, this role is not well defined.</div></div><div><h3>Objectives</h3><div>This study explored health professionals' and kidney transplant recipients' perceptions around the role of the pharmacist in the provision of care to kidney transplant recipients from regional, rural, and remote areas of Australia.</div></div><div><h3>Methods</h3><div>Semi-structured interviews and focus group discussions were conducted with Australian kidney transplant health professionals and kidney transplant recipients respectively. Transcripts were analysed thematically and deductively coded using a simplified framework of role theory constructs.</div></div><div><h3>Results</h3><div>Participants consisted of a multidisciplinary cross section of transplant health professionals (<em>n</em> = 26) and both deceased and living donor kidney transplant recipients (<em>n</em> = 30). Six role theory constructs were identified from the data with regards to the pharmacist's role: role identity, role ambiguity, role overload, role overqualification, role underqualification, and role insufficiency. Core role expectations centred around provision of ongoing education and support with medication management and supply (role identity), however pharmacists remain underutilised for delivery of medication education (role overqualification). A transdisciplinary model of care was suggested to overcome current shortfalls (role overload, role insufficiency). There was hesitancy around pharmacist-led immunosuppressant monitoring and titration (role ambiguity, role underqualification).</div></div><div><h3>Conclusions</h3><div>Kidney transplant recipients in regional, rural, and remote areas experience unique barriers and challenges associated with medication management, necessitating an increased level of involvement and support from the pharmacist.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100587"},"PeriodicalIF":1.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of recommendations, efficacy, and patient safety for over-the-counter norgestrel for daily contraception 非处方诺孕酮用于日常避孕的推荐、疗效和患者安全性综述
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-11 DOI: 10.1016/j.rcsop.2025.100591
Gia Tran , Joshua Wollen , Shantera Davis , Elisabeth M. Wang , Julia Arriazola , Natalie Rosario
{"title":"A review of recommendations, efficacy, and patient safety for over-the-counter norgestrel for daily contraception","authors":"Gia Tran ,&nbsp;Joshua Wollen ,&nbsp;Shantera Davis ,&nbsp;Elisabeth M. Wang ,&nbsp;Julia Arriazola ,&nbsp;Natalie Rosario","doi":"10.1016/j.rcsop.2025.100591","DOIUrl":"10.1016/j.rcsop.2025.100591","url":null,"abstract":"<div><h3>Purpose</h3><div>This narrative review examines the implications of norgestrel, a progestin-only oral contraceptive, becoming newly available over-the-counter (OTC) in the United States. The objectives are to explore the pharmacotherapy,mechanism of action, efficacy, safety, and implications to clinical practice of OTC progestin-only pills (POPs), and how this may impact contraceptive access and public health.</div></div><div><h3>Methods</h3><div>The review synthesizes data from clinical studies, public health reports, global perspectives, and recent policy changes to assess the potential impact of OTC access to norgestrel in the United States. The analysis includes the evaluation of the pharmacodynamics of norgestrel 0.075 mg on ovarian activity, the effectiveness of POPs, and benefits and barriers to contraceptive access.</div></div><div><h3>Findings</h3><div>The evidence indicates that POPs thickens cervical mucus, providing effective contraception within 48 h of use. While ovulation inhibition may take up to 28 days and occurs in approximately half of users, the availability of POPs OTC is anticipated to significantly reduce barriers to contraceptive access. This could lead to a broader use of effective contraception and potentially reduce unintended pregnancies. Additionally, the review highlights that the introduction of OTC contraceptives could increase access among populations historically facing difficulties in obtaining prescriptions.</div></div><div><h3>Conclusions</h3><div>Making norgestrel available OTC represents a critical advancement in contraceptive access with the potential to enhance public health by reducing unintended pregnancies. However, the extent of its impact will depend on widespread education and adherence to proper use. The review underscores the need for further research to monitor outcomes post-OTC availability and to assess the broader implications for reproductive health and equity.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100591"},"PeriodicalIF":1.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shifting the mindset regarding adherence to antibiotic use for respiratory tract infections 改变坚持使用抗生素治疗呼吸道感染的观念
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-11 DOI: 10.1016/j.rcsop.2025.100588
Carl Llor
{"title":"Shifting the mindset regarding adherence to antibiotic use for respiratory tract infections","authors":"Carl Llor","doi":"10.1016/j.rcsop.2025.100588","DOIUrl":"10.1016/j.rcsop.2025.100588","url":null,"abstract":"<div><div>Some papers emphasize adherence to antibiotic therapy, but a paradigm shift is needed. While nonadherence may impact chronic conditions, it has not been proven to affect community respiratory tract infections outside of tuberculosis. Respiratory infections, which account for most community antibiotic prescriptions, often involve inappropriate antibiotic use, even in developed countries, with up to 80 % of consultations resulting in prescriptions. Over-the-counter sales of antibiotics further exacerbate this issue. Research should explore whether stopping antibiotics after symptom resolution, rather than completing the full course, is feasible for non-severe infections. Shorter antibiotic courses have shown similar effectiveness with fewer side effects, aligning with the “shorter is better” principle. The idea that completing the entire antibiotic course prevents antimicrobial resistance remains unproven. Instead, longer exposure to antibiotics increases resistance. A patient-centered approach, focusing on outcomes, is essential for the future of antibiotic stewardship.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100588"},"PeriodicalIF":1.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the effect of computer-based education on pharmacist behaviour regarding point-of-care testing 评估以电脑为基础的教育对药剂师即时检验行为的影响
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-07 DOI: 10.1016/j.rcsop.2025.100586
Rand Hussein , Nardine Nakhla , Kyu Min Shim , Joslin Goh , Rosemary Killeen , Kelly Grindrod
{"title":"Evaluating the effect of computer-based education on pharmacist behaviour regarding point-of-care testing","authors":"Rand Hussein ,&nbsp;Nardine Nakhla ,&nbsp;Kyu Min Shim ,&nbsp;Joslin Goh ,&nbsp;Rosemary Killeen ,&nbsp;Kelly Grindrod","doi":"10.1016/j.rcsop.2025.100586","DOIUrl":"10.1016/j.rcsop.2025.100586","url":null,"abstract":"<div><h3>Background</h3><div>Recent regulatory changes in Ontario have enabled pharmacists to perform point-of-care testing (POCT) to manage chronic diseases. With the introduction of any new service(s), educational interventions can aid acceptance and implementation. Computer-based education (CBE) improves pharmacists' knowledge, but there is little evidence of its effect on pharmacist behaviour. This study assessed the impact of CBE on pharmacist knowledge, behaviour intention, and adoption of POCT.</div></div><div><h3>Methods</h3><div>A three-month, web-based, randomized controlled trial was conducted between April 2024 and Sep 2024 with community pharmacists in Ontario, Canada. The intervention group was asked to complete two POCT modules using a CBE platform, while the control group was asked to review reference materials about POCTs. The primary outcome, the difference in the number of POCTs performed, was collected using monthly reports. Secondary outcomes (knowledge gain and changes in the Theory of Planned Behaviour (TPB) constructs: attitude, subjective norm, perceived behavioural control, and behaviour intention) were assessed using selfreported surveys. Generalized linear models (GLM) with negative binomial distribution were used to analyze the number of POCTs. Knowledge gain was analyzed using repeated measure ANOVA and binomial regression. TPB constructs were analyzed within groups using paired sample <em>t</em>-tests and between groups using two-sample ttests.</div></div><div><h3>Results</h3><div>Of the 261 pharmacists recruited, 201 completed the pre-study survey, 135 completed the one-week post-test, and 104 completed the three-month post-test. There was a significant difference in knowledge test scores between the two groups at one week (<em>P</em> = .001) and three months (<em>P</em> &lt; .00). There was no significant difference in behavioural constructs between the two groups at three months. However, attitude increased significantly for both groups (intervention group 3.6 ± 0.6 Vs. 3.95 ± 0.5 <em>P</em> &lt; .001; control group 3.5 ± 0.6 Vs. 3.8 ± 0.5 P &lt; .001). There was no significant change in the number of POCTs performed after one, two, and three months for both study groups.</div></div><div><h3>Conclusion</h3><div>CBE improved pharmacists' knowledge of POCT but showed a limited effect on pharmacist intention or behaviour. The study highlighted that knowledge alone does not influence behaviour change. Factors such as organizational support, adequate reimbursement, and expanded practice scope (e.g., prescribing) are critical to enhance POCT implementation.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"18 ","pages":"Article 100586"},"PeriodicalIF":1.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interdisciplinary medication reviews of psychiatric patients – A mixed method evaluation 精神病患者的跨学科药物评价-一种混合方法评价
IF 1.8
Exploratory research in clinical and social pharmacy Pub Date : 2025-03-02 DOI: 10.1016/j.rcsop.2025.100584
Dagmar Abelone Dalin , Sara Sommer Holst , Lucif Søemosegaard Dalin , Charlotte Vermehren
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