Advances in applied microbiology最新文献_第4页

Role of psychrotrophic bacteria and cold-active enzymes in composting methods adopted in cold regions. 冷养细菌和冷活性酶在寒冷地区堆肥方法中的作用。

2区生物学

Advances in applied microbiology Pub Date : 2022-01-01 DOI: 10.1016/bs.aambs.2022.08.001

Vivek Manyapu, Ayush Lepcha, Sanjeev Kumar Sharma, Rakshak Kumar

引用次数: 0

Gain-of-function research. 功能的研究。

2区生物学

Advances in applied microbiology Pub Date : 2022-01-01 DOI: 10.1016/bs.aambs.2022.06.002

K P Saalbach

{"title":"Gain-of-function research.","authors":"K P Saalbach","doi":"10.1016/bs.aambs.2022.06.002","DOIUrl":"https://doi.org/10.1016/bs.aambs.2022.06.002","url":null,"abstract":"The term Gain-of-Function (GoF) describes the gain of new functions by organisms through genetic changes, which can naturally occur or by experimental genetic modifications. Gain-of-Function research on viruses is enhancing transmissibility, virus replication, virulence, host range, immune evasion or drug and vaccine resistance to get insights into the viral mechanisms, to create and analyze animal models, to accelerate drug and vaccine development and to improve pandemic preparedness. A subset is the GoF research of concern (GOFROC) on enhanced potentially pandemic pathogens (ePPPs) that could be harmful for humans. A related issue is the military use of research as dual-use research of concern (DURC). Influenza and coronaviruses are main research targets, because they cause pandemics by airborne infections. Two studies on avian influenza viruses initiated a global debate and a temporary GoF pause in the United States which ended with a new regulatory framework in 2017. In the European Union and China, GoF and DURC are mainly covered by the legislation for laboratory safety and genetically modified organisms. After the coronavirus outbreaks, the GoF research made significant advances, including analyses of modified MERS-like and SARS-like viruses and the creation of synthetic SARS-CoV-2 viruses as a platform to generate mutations. The GoF research on viruses will still play an important role in future, but the need to clarify the differences and overlaps between GoF research, GOFROC and DURC and the need for specialized oversight authorities are still debated.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"120 ","pages":"79-111"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10626343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Advances in microbial production of feed amino acid. 饲料氨基酸微生物生产研究进展。

2区生物学

Advances in applied microbiology Pub Date : 2022-01-01 DOI: 10.1016/bs.aambs.2022.05.001

Kuo Zhao, Jianmin Liu, Cong Gao, Jia Liu, Xiulai Chen, Liming Liu, Liang Guo

引用次数: 1

The use of the electromagnetic field in microbial process bioengineering. 电磁场在微生物过程生物工程中的应用。

2区生物学

Advances in applied microbiology Pub Date : 2022-01-01 DOI: 10.1016/bs.aambs.2022.08.002

Joanna Jabłońska, Kamila Dubrowska, Marta Gliźniewicz, Oliwia Paszkiewicz, Adrian Augustyniak, Bartłomiej Grygorcewicz, Maciej Konopacki, Agata Markowska-Szczupak, Marian Kordas, Barbara Dołęgowska, Rafał Rakoczy

{"title":"The use of the electromagnetic field in microbial process bioengineering.","authors":"Joanna Jabłońska, Kamila Dubrowska, Marta Gliźniewicz, Oliwia Paszkiewicz, Adrian Augustyniak, Bartłomiej Grygorcewicz, Maciej Konopacki, Agata Markowska-Szczupak, Marian Kordas, Barbara Dołęgowska, Rafał Rakoczy","doi":"10.1016/bs.aambs.2022.08.002","DOIUrl":"https://doi.org/10.1016/bs.aambs.2022.08.002","url":null,"abstract":"An electromagnetic field (EMF) has been shown to have various stimulatory or inhibitory effects on microorganisms. Over the years, growing interest in this topic led to numerous discoveries suggesting the potential applicability of EMF in biotechnological processes. Among these observations are stimulative effects of this physical influence resulting in intensified biomass production, modification of metabolic activity, or pigments secretion. In this review, we present the current state of the art and underline the main findings of the application of EMF in bioprocessing and their practical meaning in process engineering using examples selected from studies on bacteria, archaea, microscopic fungi and yeasts, viruses, and microalgae. All biological data are presented concerning the classification of EMF. Furthermore, we aimed to highlight missing parts of contemporary knowledge and indicate weak spots in the approaches found in the literature.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"121 ","pages":"27-72"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10638086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Uninvited Guests: a Chronology of Petri Dish Contaminations. 不速之客:培养皿污染年表。

2区生物学

Advances in applied microbiology Pub Date : 2021-01-01 Epub Date: 2021-05-27 DOI: 10.1016/bs.aambs.2021.04.002

Gilbert Shama

引用次数: 1

Copyright 版权

2区生物学

Advances in applied microbiology Pub Date : 2021-01-01 DOI: 10.1016/s0065-2164(21)00029-0

引用次数: 0

Molecular engineering to improve lignocellulosic biomass based applications using filamentous fungi. 利用丝状真菌改进木质纤维素生物质应用的分子工程。

2区生物学

Advances in applied microbiology Pub Date : 2021-01-01 Epub Date: 2020-10-17 DOI: 10.1016/bs.aambs.2020.09.001

Jiali Meng, Miia R Mäkelä, Ronald P de Vries

引用次数: 8

Biological treatments of mercury and nitrogen oxides in flue gas: biochemical foundations, technological potentials, and recent advances. 烟气中汞和氮氧化物的生物处理:生化基础、技术潜力和最新进展。

2区生物学

Advances in applied microbiology Pub Date : 2021-01-01 Epub Date: 2021-05-19 DOI: 10.1016/bs.aambs.2021.04.001

Zhenshan Huang, Zaishan Wei, Meiru Tang, Shan Yu, Huaiyong Jiao

引用次数: 0

Synthesis of functional oligosaccharides and their derivatives through cocultivation and cellular NTP regeneration. 通过共培养和细胞NTP再生合成功能性低聚糖及其衍生物。

2区生物学

Advances in applied microbiology Pub Date : 2021-01-01 Epub Date: 2021-05-03 DOI: 10.1016/bs.aambs.2021.02.002

Jianrong Wu, Ruoyu Yang, Minjie Gao, Hongtao Zhang, Xiaobei Zhan

{"title":"Synthesis of functional oligosaccharides and their derivatives through cocultivation and cellular NTP regeneration.","authors":"Jianrong Wu, Ruoyu Yang, Minjie Gao, Hongtao Zhang, Xiaobei Zhan","doi":"10.1016/bs.aambs.2021.02.002","DOIUrl":"https://doi.org/10.1016/bs.aambs.2021.02.002","url":null,"abstract":"Carbohydrates play an important role in the life cycle. Among them, functional oligosaccharides show a complex and diverse structures with unique physiological activities and biological functions. However, different preparation methods directly affect the structure, molecular weight, and other functions of oligosaccharides, as well as their application fields and manufacturing costs. In the preparation of β-1,3-glucan oligosaccharides (OBGs), water insolubility of β-1,3-glucans hampers the hydrolysis efficiency. The synthesis of some functional oligosaccharides requires the consumption of energy substrates, such as ATP, CTP, and uridine triphosphate, for sugar nucleotide synthesis, leading to increased capital costs. A more economical solution to solve energy supply is to adopt microbial cocultivation or cellular nucleoside triphosphate regeneration. This review focused on the sources, preparation methods, biological activities of OBG, and the cultivation methods and applications of microbial cocultivation and fermentation. We also reviewed the preparation methods of other functional oligosaccharides, such as sialylated oligosaccharides, β-nicotinamide mononucleotide, and α-galacto-oligosaccharides.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"115 ","pages":"35-63"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.aambs.2021.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39242243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Lipid production by oleaginous yeasts. 产油酵母产脂。

2区生物学

Advances in applied microbiology Pub Date : 2021-01-01 Epub Date: 2021-05-07 DOI: 10.1016/bs.aambs.2021.03.003

Atrayee Chattopadhyay, Mrinal K Maiti

{"title":"Lipid production by oleaginous yeasts.","authors":"Atrayee Chattopadhyay, Mrinal K Maiti","doi":"10.1016/bs.aambs.2021.03.003","DOIUrl":"https://doi.org/10.1016/bs.aambs.2021.03.003","url":null,"abstract":"Microbial lipid production has been studied extensively for years; however, lipid metabolic engineering in many of the extraordinarily high lipid-accumulating yeasts was impeded by inadequate understanding of the metabolic pathways including regulatory mechanisms defining their oleaginicity and the limited genetic tools available. The aim of this review is to highlight the prominent oleaginous yeast genera, emphasizing their oleaginous characteristics, in conjunction with diverse other features such as cheap carbon source utilization, withstanding the effect of inhibitory compounds, commercially favorable fatty acid composition-all supporting their future development as economically viable lipid feedstock. The unique aspects of metabolism attributing to their oleaginicity are accentuated in the pretext of outlining the various strategies successfully implemented to improve the production of lipid and lipid-derived metabolites. A large number of in silico data generated on the lipid accumulation in certain oleaginous yeasts have been carefully curated, as suggestive evidences in line with the exceptional oleaginicity of these organisms. The different genetic elements developed in these yeasts to execute such strategies have been scrupulously inspected, underlining the major types of newly-found and synthetically constructed promoters, transcription terminators, and selection markers. Additionally, there is a plethora of advanced genetic toolboxes and techniques described, which have been successfully used in oleaginous yeasts in the recent years, promoting homologous recombination, genome editing, DNA assembly, and transformation at remarkable efficiencies. They can accelerate and effectively guide the rational designing of system-wide metabolic engineering approaches pinpointing the key targets for developing industrially suitable yeast strains.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"116 ","pages":"1-98"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.aambs.2021.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39279240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8