Advances in applied microbiology最新文献

Cyanobacterial fatty acids: From biosynthesis to diverse applications. 蓝藻脂肪酸：从生物合成到不同的应用。

2区生物学

Advances in applied microbiology Pub Date : 2025-01-01 Epub Date: 2025-01-06 DOI: 10.1016/bs.aambs.2024.11.002

Akhila Punchakara, Sharon Sunny, Akhil Agrawal

{"title":"Cyanobacterial fatty acids: From biosynthesis to diverse applications.","authors":"Akhila Punchakara, Sharon Sunny, Akhil Agrawal","doi":"10.1016/bs.aambs.2024.11.002","DOIUrl":"10.1016/bs.aambs.2024.11.002","url":null,"abstract":"Blue-green algae, or cyanobacteria, is a diverse category of prokaryotic photosynthetic organisms. The capacity to extract economically viable compounds from cyanobacteria drives continuous scientific research in this domain. The ability to synthesize fatty acids from cyanobacteria makes them a useful substitute for animal and plant-based sources in the synthesis of oils and fats. Their benefits over other sources include their rapid growth rate, higher biomass production and minimal consumption of land. Since these substances build up inside of the cells, effective procedures for their extraction, recovery, and purification are required. The primary procedures in lipid extraction utilizing cyanobacteria are cultivation, biomass collection, cell disruption and lipid transesterification. Fatty acids are essential components of the metabolic pathways that generate and convert the majority of lipid classes. This chapter outlines the metabolic pathway associated with fatty acid biosynthesis, along with various mechanical and chemical methods that can be employed to extract lipids from cyanobacteria. The composition of fatty acids primarily impacts their characteristics and practical use. This chapter also gives a general overview of the variety of fatty acid profiles found in cyanobacteria, including omega-6 and omega-3 fatty acids, as well as odd-chain, long-chain, short-chain, and medium-chain fatty acids and the different uses of cyanobacterial fatty acids in various industries, such as aquaculture, biofuel, food industry, pharmaceuticals, cosmetics and more. In summary cyanobacterial fatty acids are essential in various fields, offering benefits for both ecosystems and emerging industries.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"130 ","pages":"191-205"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Substrate effects on the growth, yield, and nutritional composition of edible mushrooms. 基质对食用菌生长、产量和营养成分的影响。

2区生物学

Advances in applied microbiology Pub Date : 2025-01-01 Epub Date: 2025-01-06 DOI: 10.1016/bs.aambs.2024.11.005

Thaynã Gonçalves Timm, Matheus Samponi Tucunduva Arantes, Eduardo Henrique Silva de Oliveira, Lorena Benathar Ballod Tavares, Álvaro Luiz Mathias, Vítor Renan da Silva, Cristiane Vieira Helm

{"title":"Substrate effects on the growth, yield, and nutritional composition of edible mushrooms.","authors":"Thaynã Gonçalves Timm, Matheus Samponi Tucunduva Arantes, Eduardo Henrique Silva de Oliveira, Lorena Benathar Ballod Tavares, Álvaro Luiz Mathias, Vítor Renan da Silva, Cristiane Vieira Helm","doi":"10.1016/bs.aambs.2024.11.005","DOIUrl":"10.1016/bs.aambs.2024.11.005","url":null,"abstract":"Edible mushrooms are a valuable source of protein, dietary fiber, vitamins, essential elements, and bioactive compounds with significant nutraceutical benefits for human health. Their popularity has grown in recent years due to their gluten-free nature and essential amino acid profile, making them appealing to vegetarians, vegans, and individuals with celiac disease. The nutritional composition and biological efficiency of mushrooms depend on the species and production system, particularly the substrate used and cultivation conditions. This review explores how different substrates, particularly those containing agribusiness by-products, affect mushrooms' productivity, nutritional, and element content from the Agaricus, Lentinula, and Pleurotus genera. It underscores the importance of these mushrooms in the human diet and highlights how using agro-industrial wastes as substrates offers a sustainable cultivation method. This approach supports a circular bioeconomy, providing an ecologically and economically viable solution while aiding in waste recovery and minimizing environmental impacts associated with improper disposal of agro-industrial wastes.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"130 ","pages":"159-190"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aldo-keto reductases, short chain dehydrogenases/reductases, and zinc-binding dehydrogenases are key players in fungal carbon metabolism. 醛酮还原酶、短链脱氢酶/还原酶和锌结合脱氢酶是真菌碳代谢的关键分子。

2区生物学

Advances in applied microbiology Pub Date : 2025-01-01 Epub Date: 2025-01-06 DOI: 10.1016/bs.aambs.2024.11.004

Astrid Müller, Miia R Mӓkelӓ, Ronald P de Vries

{"title":"Aldo-keto reductases, short chain dehydrogenases/reductases, and zinc-binding dehydrogenases are key players in fungal carbon metabolism.","authors":"Astrid Müller, Miia R Mӓkelӓ, Ronald P de Vries","doi":"10.1016/bs.aambs.2024.11.004","DOIUrl":"10.1016/bs.aambs.2024.11.004","url":null,"abstract":"Carbon metabolism is an essential process in fungal physiology, balancing energy availability, growth, and survival through the assimilation and breakdown of organic carbon sources. This review focuses on three major families of oxidoreductases that play central roles in fungal carbon metabolism: PF00248, PF00106, and PF00107. These enzymes are not only crucial for energy production but also for the synthesis and breakdown of complex organic molecules. PF00248, the aldo-keto reductase superfamily, is involved in a wide range of redox reactions, while PF00106 includes diverse short-chain reductase/dehydrogenases important for fungal growth and environmental adaptation. PF00107 comprises zinc-binding dehydrogenases with a role in processes such as alcohol metabolism and zinc uptake. These oxidoreductases are evolutionarily conserved with respect to amino acid sequence motifs but show significant genetic diversity across fungal species, reflecting their ecological adaptability and metabolic versatility. Understanding the functions within these enzyme families can enhance the design of efficient fungal cell factories for biotechnological applications, such as biofuel and biochemical production from plant biomass. This review highlights the importance of these enzymes in central carbon metabolism and their potential for industrial applications.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"130 ","pages":"123-157"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organic (methyl-, ethyl-, phenyl-) and total mercury (Hg) in fungal biomass: The influence of species, substrates, source proximity and analytics on reported occurrences. 真菌生物量中的有机汞（甲基、乙基、苯基）和总汞（Hg）：种类、底物、源邻近性和分析对报告发生的影响。

2区生物学

Advances in applied microbiology Pub Date : 2025-01-01 Epub Date: 2025-01-06 DOI: 10.1016/bs.aambs.2024.11.001

Jerzy Falandysz, Alwyn R Fernandes, Heesoo Eun

{"title":"Organic (methyl-, ethyl-, phenyl-) and total mercury (Hg) in fungal biomass: The influence of species, substrates, source proximity and analytics on reported occurrences.","authors":"Jerzy Falandysz, Alwyn R Fernandes, Heesoo Eun","doi":"10.1016/bs.aambs.2024.11.001","DOIUrl":"10.1016/bs.aambs.2024.11.001","url":null,"abstract":"Mercury occurs in inorganic and organic forms in abiotic and biotic environments, food and humans. Diet is a primary pathway to chronic exposure and the Hg content of food is regulated, including the three most cultivated edible fungi. The reliable determination of total Hg and organo-Hg compounds in fungi is therefore crucial from the regulatory and human exposure viewpoint. So far, no fungal species have been identified that exhibit mercury hyperaccumulation. Chronologically, external fungal biomass decomposition, elementary Hg0 vapour generation and cold vapour-atomic absorption spectroscopy measurement was the first popular instrument technique used to measure Hg in mushrooms. In more recent time, chemical vapour generation - atomic fluorescence spectrometry is getting more popular. Radiochemical analysis, instrumental neutron activation analysis, electrothermal atomic absorption spectrometry and electrochemical techniques (anodic stripping voltammetry, differential pulsed anodic stripping voltammetry and potentiometry) were occasionally used. More recently and going forward, ICP-MS technique that allow precise measurement of multiple elements including Hg simultaneously are likely to most widely used. For speciation studies of Hg in fungal biomass, CV-AAS and a variation of the instrumental couplings of gas- and liquid chromatography (combined with chemical vapor generation) and non-chromatographic separations with various detectors have been used. From the use of L-cysteine as a complexing agent to the quantitative capture and determination of MeHg in various matrices, a number of applications, modifications and updates to the methodology have been introduced since then. L-cysteine has the potential to capture MeHg, EtHg and PhHg or possibly any organo-Hg compound in a sample extract.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"130 ","pages":"1-122"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How Metarhizium robertsii's mycelial consciousness gets its conidia Zen-ready for stress. Metarhizium robertsii 的菌丝意识如何让它的分生孢子禅定地应对压力。

2区生物学

Advances in applied microbiology Pub Date : 2024-01-01 Epub Date: 2024-07-26 DOI: 10.1016/bs.aambs.2024.07.002

Drauzio Eduardo Naretto Rangel

引用次数: 0

The colorful fungi of the Chilean forests: Production, chemical characterization and possible applications of their pigments. 智利森林中色彩斑斓的真菌：其色素的生产、化学特征和可能的应用。

2区生物学

Advances in applied microbiology Pub Date : 2024-01-01 Epub Date: 2024-06-19 DOI: 10.1016/bs.aambs.2024.05.003

Ángela Machuca, Vicente A Hernández, Christian Deramond, Paulina Contreras-Machuca

{"title":"The colorful fungi of the Chilean forests: Production, chemical characterization and possible applications of their pigments.","authors":"Ángela Machuca, Vicente A Hernández, Christian Deramond, Paulina Contreras-Machuca","doi":"10.1016/bs.aambs.2024.05.003","DOIUrl":"10.1016/bs.aambs.2024.05.003","url":null,"abstract":"In Chile, as in the rest of the world, only a small fraction of the fungal diversity inhabiting the wide variety of its ecosystems is known. This diversity must hide an inestimable richness of species with interesting biotechnological potential, including fungal pigment producers. Recently, interest in filamentous fungi has increased significantly due to their importance as alternative sources of pigments and colorants that are environmentally and human health friendly. As a result, fungal pigments are gaining importance in various industrial applications, such as food, textiles, pharmaceuticals, cosmetics, etc. The increasing consumer demand for \"green label\" natural colorants requires the exploration of different ecosystems in search of new fungal species that are efficient producers of different pigment with a wide range of colors and ideally without the co-production of mycotoxins. However, advances are also needed in pigment production processes through fermentation, scale-up from laboratory to industrial scale, and final product formulation and marketing. In this respect, the journey is still full of challenges for scientists and entrepreneurs. This chapter describes studies on pigment-producing fungi collected in the forests of central-southern Chile. Aspects such as the exploration of potential candidates as sources of extracellular pigments, the optimization of pigment production by submerged fermentation, methods of pigment extraction and purification for subsequent chemical characterization, and formulation (by microencapsulation) for potential cosmetic applications are highlighted. This potential use is due to the outstanding bioactivity of most fungal pigments, making them interesting functional ingredients for many applications. Finally, the use of fungal pigments for textile and spalting applications is discussed.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"128 ","pages":"1-40"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141764788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Penicillium chrysogenum: Beyond the penicillin. 蛹青霉：超越青霉素

2区生物学

Advances in applied microbiology Pub Date : 2024-01-01 Epub Date: 2024-04-16 DOI: 10.1016/bs.aambs.2024.02.006

Carlos Barreiro, Silvia M Albillos, Carlos García-Estrada

引用次数: 0

Application of synthetic biology strategies to promote biosynthesis of fatty acids and their derivatives. 应用合成生物学策略促进脂肪酸及其衍生物的生物合成。

2区生物学

Advances in applied microbiology Pub Date : 2024-01-01 Epub Date: 2024-06-15 DOI: 10.1016/bs.aambs.2024.05.002

Haiqian Yang, Jie Gao, Xiaowei Peng, Yejun Han

{"title":"Application of synthetic biology strategies to promote biosynthesis of fatty acids and their derivatives.","authors":"Haiqian Yang, Jie Gao, Xiaowei Peng, Yejun Han","doi":"10.1016/bs.aambs.2024.05.002","DOIUrl":"10.1016/bs.aambs.2024.05.002","url":null,"abstract":"Fatty acids and their derivatives are indispensable biomolecules in all organisms, and can be used as intermediates in the synthesis of pharmaceuticals, biofuels and pesticides, and thus their demand has increased dramatically in recent years. In addition to serving as structural components of cell membranes and metabolic energy, fatty acids and their derivatives can also be used as signal transduction and regulatory bioactive molecules to regulate cell functions. Biosynthesis of fatty acids and their derivatives through microbial catalysis provides green and alternative options to meet the goal. However, the low biosynthetic titer of fatty acids and their derivatives limits their industrial production and application. In this review, we first summarize the metabolic pathways and related enzymes of fatty acids and their derivatives biosynthesis. Then, the strategies and research progress of biosynthesis of fatty acids and derivatives through metabolic and enzyme engineering were reviewed. The biosynthesis of saturated fatty acids (medium chain fatty acids and long chain fatty acids), bioactive fatty acids (PUFAs, oxylipins, ether lipids), and their derivatives with microbial and enzymatic catalysis were respectively summarized. Finally, synthetic biology strategies to improve fatty acids and their derivatives production through enzyme rational design, carbon metabolism flux, cofactors balance, and metabolic pathways design were discussed. The review provides references and prospects for fatty acids and their derivatives biosynthesis and industrial production.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"128 ","pages":"83-104"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141764787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selenium bioactive compounds produced by beneficial microbes. 有益微生物产生的硒生物活性化合物。

2区生物学

Advances in applied microbiology Pub Date : 2024-01-01 Epub Date: 2024-03-29 DOI: 10.1016/bs.aambs.2024.02.004

L Crespo, B Sede Lucena, F G Martínez, F Mozzi, M Pescuma

{"title":"Selenium bioactive compounds produced by beneficial microbes.","authors":"L Crespo, B Sede Lucena, F G Martínez, F Mozzi, M Pescuma","doi":"10.1016/bs.aambs.2024.02.004","DOIUrl":"10.1016/bs.aambs.2024.02.004","url":null,"abstract":"Selenium (Se) is an essential trace element present as selenocysteine (SeCys) in selenoproteins, which have an important role in thyroid metabolism and the redox system in humans. Se deficiency affects between 500 and 1000 million people worldwide. Increasing Se intake can prevent from bacterial and viral infections. Se deficiency has been associated with cancer, Alzheimer, Parkinson, decreased thyroid function, and male infertility. Se intake depends on the food consumed which is directly related to the amount of Se in the soil as well as on its availability. Se is unevenly distributed on the earth's crust, being scarce in some regions and in excess in others. The easiest way to counteract the symptoms of Se deficiency is to enhance the Se status of the human diet. Se salts are the most toxic form of Se, while Se amino acids and Se-nanoparticles (SeNPs) are the least toxic and most bio-available forms. Some bacteria transform Se salts into these Se species. Generally accepted as safe selenized microorganisms can be directly used in the manufacture of selenized fermented and/or probiotic foods. On the other hand, plant growth-promoting bacteria and/or the SeNPs produced by them can be used to promote plant growth and produce crops enriched with Se. In this chapter we discuss bacterial Se metabolism, the effect of Se on human health, the applications of SeNPs and Se-enriched bacteria, as well as their effect on food fortification. Different strategies to counteract Se deficiency by enriching foods using sustainable strategies and their possible implications for improving human health are discussed.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"126 ","pages":"63-92"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in microbial astaxanthin production. 微生物虾青素生产的进展。

2区生物学

Advances in applied microbiology Pub Date : 2024-01-01 Epub Date: 2024-07-01 DOI: 10.1016/bs.aambs.2024.05.001

Cassamo U Mussagy

{"title":"Advances in microbial astaxanthin production.","authors":"Cassamo U Mussagy","doi":"10.1016/bs.aambs.2024.05.001","DOIUrl":"10.1016/bs.aambs.2024.05.001","url":null,"abstract":"This work explores astaxanthin (AXT), a valuable xanthophyll ketocarotenoid pigment with significant health benefits and diverse applications across various industries. It discusses the prevalence of synthetic AXT, and the development of natural-based alternatives derived from microorganisms such as microalgae, bacteria, and yeast. The chapter examines the potential of microbial AXT production, highlighting the advantages and challenges associated with natural AXT. Key microorganisms like Haematococcus pluvialis, Paracoccus carotinifaciens, and Phaffia rhodozyma are emphasized for their role in commercially producing this valuable ketocarotenoid. The narrative covers the complexities and opportunities in microbial AXT production, from cell structure implications to downstream processing strategies. Additionally, the chapter addresses current applications, commercialization trends, and market dynamics of natural microbial AXT, emphasizing the importance of cost-effective production, regulatory compliance, and technological advancements to reduce the market cost of the final product. As demand for natural microbial-based AXT rises, this chapter envisions a future where research, innovation, and collaboration drive sustainable and competitive microbial AXT production, fostering growth in this dynamic market.","PeriodicalId":7298,"journal":{"name":"Advances in applied microbiology","volume":"128 ","pages":"105-120"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141764786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0