Rita González-Resina , Laura Eva Franco-Fobe , Concepción López-Gómez , Isabel Izquierdo-García
{"title":"Probable breakthrough fungal infection in immunocompromised patient with isolation of an infrequent species","authors":"Rita González-Resina , Laura Eva Franco-Fobe , Concepción López-Gómez , Isabel Izquierdo-García","doi":"10.1016/j.eimce.2024.08.003","DOIUrl":"10.1016/j.eimce.2024.08.003","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 1","pages":"Pages 53-54"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pilar Arrazola , María Fernández Prada , Ángel Gil , José Gómez Rial , Cristina Hernán , Rosario Menéndez , Antoni Trilla , Raúl Ortiz de Lejarazu
{"title":"New COVID-19 vaccination recommendations in Spain: Optimizing for next seasons","authors":"Pilar Arrazola , María Fernández Prada , Ángel Gil , José Gómez Rial , Cristina Hernán , Rosario Menéndez , Antoni Trilla , Raúl Ortiz de Lejarazu","doi":"10.1016/j.eimce.2024.08.006","DOIUrl":"10.1016/j.eimce.2024.08.006","url":null,"abstract":"<div><div>Despite high initial vaccination rates, Spain's current COVID-19 vaccination coverage in recommended groups does not meet WHO targets. For the upcoming season, challenges include revising vaccination age, updating risk groups, and unifying criteria with flu vaccine co-administration. European Commission's advance purchase agreements limit access to certain vaccines, and the need for vaccines effective against current variants adds administrative complexities. Spain's COVID-19 vaccination recommendations should adapt to these specific circumstances. Using vaccines effective against predominant variants with appropriate response duration is crucial to protect at-risk populations. Enhancing training and health education campaigns for health professionals and the general public, alongside utilizing tools to simplify vaccination recommendations, can promote higher vaccination rates in Spain. Addressing these challenges is essential to ensure adequate protection and improve vaccination coverage, ultimately achieving better public health outcomes in the face of evolving COVID-19 threats.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 1","pages":"Pages 36-46"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"More threats: The increase in tick-borne diseases and their spectrum","authors":"José A. Oteo, Ana M. Palomar","doi":"10.1016/j.eimce.2024.10.005","DOIUrl":"10.1016/j.eimce.2024.10.005","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 1","pages":"Pages 1-2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are corticosteroids safe in adolescent and adult patients with infectious mononucleosis? A retrospective cohort study","authors":"Emilio-Manuel Páez-Guillán, Joaquín Campos-Franco, Rosario Alende, Arturo González-Quintela","doi":"10.1016/j.eimce.2023.10.005","DOIUrl":"10.1016/j.eimce.2023.10.005","url":null,"abstract":"<div><h3>Background and aim</h3><div>The use of systemic corticosteroids during Epstein-Barr virus (EBV)-induced infectious mononucleosis<span> is a controversial but widespread practice. We aimed to investigate the frequency of complications in adolescents and adults with infectious mononucleosis in relation to the use of corticosteroids.</span></div></div><div><h3>Methods</h3><div>We reviewed the clinical records of 396 patients admitted to the hospital with infectious mononucleosis (52.0% male; median age, 19 years; range, 15–87 years), with a focus on both short-term (infectious and non-infectious) and long-term (hematological malignancies) complications in relation to corticosteroid use.</div></div><div><h3>Results</h3><div>A total of 155 (38.6%) patients received corticosteroids at some point during infectious mononucleosis. Corticosteroid use was significantly (<em>P</em> <!-->≤<!--> <!-->0.002) associated with sore throat, lymphadenopathy, leukocytosis, and with antibiotics use (mainly indicated after suspicion of tonsillar bacterial superinfection). Overall, 139/155 (89.7%) patients who were treated with corticosteroids also received antibiotics either before or during hospitalization, compared with 168/241 (69.7%) patients who did not. The frequency of short-term severe complications, either infectious (peritonsillar–parapharyngeal abscess or bacteremia) or non-infectious (splenic rupture, severe thrombocytopenia, myopericarditis, or lymphocytic meningitis) were similar in patients receiving and not receiving corticosteroids. After a median of 15 years of follow-up, only one Hodgkin's lymphoma was diagnosed, in a patient who was not treated with corticosteroids during infectious mononucleosis.</div></div><div><h3>Conclusions</h3><div>The use of systemic corticosteroids during EBV-induced infectious mononucleosis is generally safe, at least with concomitant antibiotic therapy. However, this should not encourage the use of corticosteroids in this context, given that their efficacy has yet to be demonstrated.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 1","pages":"Pages 10-16"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139433259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helena Miriam Lorenzo Juanes , Montserrat Alonso-Sardón , Belen Vicente , Beatriz Rodríguez Alonso , Amparo López-Bernus , Josue Pendones Ulerio , Rufino Alamo Sanz , Antonio Muro , Juan Luis Muñoz Bellido , Moncef Belhassen-García
{"title":"Screening for Crimean-Congo Haemorrhagic Fever Virus antibodies in humans living in an endemic area of Spain","authors":"Helena Miriam Lorenzo Juanes , Montserrat Alonso-Sardón , Belen Vicente , Beatriz Rodríguez Alonso , Amparo López-Bernus , Josue Pendones Ulerio , Rufino Alamo Sanz , Antonio Muro , Juan Luis Muñoz Bellido , Moncef Belhassen-García","doi":"10.1016/j.eimce.2024.09.009","DOIUrl":"10.1016/j.eimce.2024.09.009","url":null,"abstract":"<div><h3>Introduction</h3><div>Crimean-Congo haemorrhagic fever (CCHF) is an emerging tick-borne viral disease. It has been described in Spain in both ticks and humans. Until July 2024 most cases have been described in the central-western part of the Iberian Peninsula. This study aims to assess the seroprevalence of antibodies against CCHF virus (CCHFV) in humans in the area that has reported the highest number of cases in Spain.</div></div><div><h3>Methods</h3><div>The study was conducted to estimate the seroprevalence of antibodies against CCHFV antibodies among patients referred to a hospital located in the central-western area of Spain, an endemic area for CCHFV of Spain. Patients were recruited from April 1, 2023, to June 30, 2023. A commercial ELISA was used to detect serum antibodies against the CCHFV.</div></div><div><h3>Results</h3><div>We screened 658 samples from 370 (56.2%) men, with a mean (±SD) age of 58.6 years (±14.3). Of these, 4 were IgG positive, representing an IgG seropositivity of 0.6% (95% CI, 0.01–1.19). None of these four patients recalled having a clinical picture that strongly suggested CCHF.</div><div>Over the study period, in the population analysed in an area with circulation of CCHFV the seroprevalence of antibodies was 0.6%.</div></div><div><h3>Conclusion</h3><div>Our results suggest active circulation of the virus in humans in western Spain. Although the risk of developing CCHF is currently considered low, physicians should be alert to the imminent possibility of developing new cases of CCHF.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 1","pages":"Pages 23-27"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Jose Muñoz Davila , Maria Teresa Cabezas Fernandez , Ana Belen Esteban García , Miguel José Martinez Lirola
{"title":"A simple MALDI–TOF-MS method for the identification of non-mycobacterial aerobic actinomycetes growing on blood agar subcultures from positive MGIT cultures","authors":"Maria Jose Muñoz Davila , Maria Teresa Cabezas Fernandez , Ana Belen Esteban García , Miguel José Martinez Lirola","doi":"10.1016/j.eimce.2024.08.005","DOIUrl":"10.1016/j.eimce.2024.08.005","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 1","pages":"Pages 55-57"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Idoia Bilbao , María Pascual , José Ramón Yuste , José Luis del Pozo
{"title":"Accidental intravenous probiotic injection in an immunocompromised patient: Implications and consequences","authors":"Idoia Bilbao , María Pascual , José Ramón Yuste , José Luis del Pozo","doi":"10.1016/j.eimce.2024.08.004","DOIUrl":"10.1016/j.eimce.2024.08.004","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 1","pages":"Pages 58-59"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}