Enfermedades infecciosas y microbiologia clinica (English ed.)最新文献

{"title":"Comparison of two chemiluminescence assays for the detection of Helicobacter pylori antigen in stool samples.","authors":"Alba García-Sáez, Blanca Carrasco, Óscar Cuevas, Juan-Ignacio Alós","doi":"10.1016/j.eimce.2026.503313","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503313","url":null,"abstract":"<p><strong>Introduction: </strong>Non-invasive methods, particularly stool antigen detection, are widely employed for the diagnosis of Helicobacter pylori infection, and the evaluation of new diagnostic platforms is of practical interest. We evaluated the agreement between two chemiluminescence techniques, CLIA LIAISON® H. pylori SA and the recently developed H. pylori Ag VIRCLIA® Monotest.</p><p><strong>Methods: </strong>We analysed 200 stool samples from patients with suspected infection.</p><p><strong>Results: </strong>92 samples were positive and 94 negative in both tests. Of the discordant samples, 9 were positive by LIAISON® and negative by VIRCLIA®, and 5 were positive by VIRCLIA® and negative by LIAISON®. Overall agreement was 93.0%, positive percent agreement (PPA) was 92.9%, and negative percent agreement (NPA) was 93.1%. Kappa coefficient was 0.86 (95% CI 0.79-0.93; p<0.0001).</p><p><strong>Conclusions: </strong>The VIRCLIA® assay demonstrated a high level of agreement with the LIAISON® assay for the detection of H. pylori stool antigen.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503313"},"PeriodicalIF":0.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149240706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Video supported treatment among vulnerable populations with tuberculosis: Data from prospective multi-centre single-arm cohort study in Catalonia, Spain.","authors":"Joan-Pau Millet, Mario Bravo-Masferrer, Xavi Casas, Andrii Dudnyk, Paquita Sánchez, Hernan Vargas-Leguas, Lydia Luque, Laura Gavaldà, M Carmen Ruíz, Miriam Montoro, Marina Lumbierres, Adrián Sánchez-Montalvá, Fina Sabrià, Virginia Pomar, Malú de Souza, Angeles Jiménez, Ignasi Parron, Pere Godoy, Cristina Rius","doi":"10.1016/j.eimce.2026.503301","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503301","url":null,"abstract":"<p><strong>Introduction: </strong>Video supported treatment (VST) is intended as a complementary or alternative approach to directly observed treatment (DOT) in patients with tuberculosis (TB) contributing to treatment adherence and patient follow-up. This study aimed to evaluate efficacy of VST using emocha mobile app (Emocha Mobile Health Inc, Baltimore, MD, USA) in the cohort of vulnerable TB patients in Catalonia, Spain.</p><p><strong>Methods: </strong>We conducted a prospective, multi-centre, single-arm, pilot implementation, study with a matched simultaneous comparison group using VST as a complementary tool to in-person DOT. Treatment adherence was measured as the proportion of validated videos over the total number expected. Odds ratios (OR) and adjusted odds ratios (aOR) assessed associations between patient characteristics and treatment success.</p><p><strong>Results: </strong>Between December 2019 and January 2023, a total of 83 (14.4%) out of 577 initially screened TB patients were enrolled receiving VST. A total of 12,346 (80.8%) video records were validated from 15,280 being scheduled. 13 out of 83 (15.7%) patients were hospitalised and then switched to in-person DOT for later treatment completion. The rate of successful treatment outcomes among patients utilizing VST either exclusively or in combination with in-person DOT was 91.6% (76/83) while 8.4% (7/83) were loss to follow-up. The success rate increased by 5% (95%CI 2-8) per each percentage point increase in the proportion of time under VST out of the total treatment duration, according to the logistic regression analysis.</p><p><strong>Conclusions: </strong>When combined with in-person DOT, VST may increase the proportion of observed doses and the likelihood of treatment success.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503301"},"PeriodicalIF":0.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149240671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond bronchoalveolar lavage: Combined CT-guided core needle biopsy and fine-needle aspiration for the diagnosis of an atypical form of pulmonary Mycobacterium avium complex infection.","authors":"Luis Gorospe, Héctor Castro-Villamor, Marta Tato-Díez","doi":"10.1016/j.eimce.2026.503303","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503303","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503303"},"PeriodicalIF":0.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149240714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Esquistosomiasis urinaria simulando tumor vesical en un paciente migrante.","authors":"Mònica Ribell Bachs, Maria Angelica Romero, Alba Prat Cantoral, Elisabet Deig Comerma","doi":"10.1016/j.eimce.2026.503311","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503311","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503311"},"PeriodicalIF":0.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149240659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rebuilding pneumococcal protection after Venezuela's 2026 earthquake doublet: A call for vaccination preparedness.","authors":"Claudia Beltrán-Arroyave, Alejandro Risquez, Maria Graciela López-Garcia, Manuela Merida, Andreina Yanes-Rojas, Jaime R Torres, Rolando Ulloa-Gutierrez, Jose Brea, Maria L Avila-Aguero, Roberto Debbag, Alfonso J Rodriguez-Morales","doi":"10.1016/j.eimce.2026.503299","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503299","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503299"},"PeriodicalIF":0.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149240647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe ocular mpox in an immunocompetent patient.","authors":"Noelia Ferreira Aparicio, Alejandra Herrera, Soledad Mendoza, Rene Carlo Manso Blázquez, Aldara Vallejo Alonso, Monica Sanchez Oñoro","doi":"10.1016/j.eimce.2026.503309","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503309","url":null,"abstract":"<p><p>Mpox, formerly known as monkeypox, is caused by Monkeypox virus (MPXV) and has been associated since 2022 with exanthematous illness in men who have sex with men (MSM), including HIV-negative individuals without prior MPXV vaccination.^1,2 The clinical course is usually self-limited, with cutaneous and mucosal involvement.^4,10,12 Severe forms, including keratoconjunctivitis and corneal ulcers, are uncommon and have mainly been linked to immunosuppression.^{2,3,5,10,12,14} We report a 20-year-old MSM male, HIV-negative, immunocompetent, and using pre-exposure prophylaxis (PrEP). He presented with generalized exanthema, right ocular pain, conjunctival injection, tearing, and periorbital cellulitis.^1,2,5,10,14 Ophthalmologic evaluation confirmed severe keratoconjunctivitis with progressive corneal ulcers.^5-7,10,11,14 MPXV PCR was positive in skin and corneal samples.^1,2,10,14 This case highlights the potential for severe ocular disease in a young, otherwise healthy patient and underscores the need for high clinical suspicion, early ophthalmologic assessment, and timely antiviral therapy.^2,4,10,15.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503309"},"PeriodicalIF":0.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149240717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic disc agar plates following enrichment broth versus direct plating onto ChromID® agar plates for surveillance of multidrug-resistant bacterial colonization: A comparative prospective study.","authors":"Monsterrat Piñana, María Ángeles Clari, Juan José Ripoll, Estela Giménez, David Navarro, Ignacio Torres","doi":"10.1016/j.eimce.2026.503291","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503291","url":null,"abstract":"<p><strong>Introduction: </strong>It remains unclear whether incorporating a pre-enrichment step in broth media enhances the sensitivity of culture-based methods for recovering multidrug-resistant organisms (MDRO) from surveillance swabs specimens.</p><p><strong>Methods: </strong>This prospective study included 364 surveillance swabs specimens. The performance of antibiotic disc agar plates following enrichment broth was compared with direct plating onto ChromID® agar plates. Additionally, 17 specimens were tested by the BIOFIRE® Blood Culture Identification 2 (BCID2) Panel to assess its added value for MDRO detection.</p><p><strong>Results: </strong>ESBL-producing Enterobacterales were recovered from 35/288 specimens after enrichment in broth and from 33/288 specimens using ChromID® ESBL agar. Carbapenemase-producing organisms were recovered from 7/288 specimens following enrichment and from 6/288 specimens using ChromID® bi-plate CARBA SMART. Vancomycin-resistant enterococci (VRE) were recovered from 7/288 specimens after enrichment and from 3/288 specimens using ChromID® VRE agar. Molecular testing additionally detected two VRE isolates missed by culture-based methods.</p><p><strong>Conclusion: </strong>Pre-enrichment in broth media mostly increases VRE detection while no substantial improvement was observed for the recovery of ESBL- or carbapenemase-producing bacteria.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503291"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic and antimicrobial stewardship programs for the management of infectious diseases in the era of artificial intelligence.","authors":"José Luis Del Pozo, Germán Bou, Rafael Cantón, Luis Martínez-Martínez, David Navarro, Jordi Vila","doi":"10.1016/j.eimce.2026.503065","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503065","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503065"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of herpes zoster cases and epidemiological trends in the Community of Madrid before and after the vaccine introduction in older adults: 2016-2025.","authors":"Laura Reques, Ana-María Humanes-Navarro, Fernando Martín, Esther Córdoba, Susana Jiménez-Bueno, Araceli Arce, Luis García-Comas","doi":"10.1016/j.eimce.2026.503295","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503295","url":null,"abstract":"<p><strong>Introduction: </strong>The Community of Madrid (CM) introduced chickenpox vaccination during childhood in 2006 and herpes zoster (HZ) vaccination for those over 65 years-old (y/o) in 2022, with progressive incorporation of age groups. This study aims to describe HZ cases and epidemiological trends between 2016 and 2025.</p><p><strong>Methods: </strong>Observational population-based study using primary care morbidity records and hospital Minimum Basic Data Set. Sociodemographic characteristics and comorbidities of the cases were described. Annual cumulative incidence (Cuml) was estimated for episodes and hospitalizations by age-group and sex. The years were grouped into three periods: 2016-19 (reference), 2020-22 (pandemic, pre-HZ vaccination) and 2023-25 (post-HZ vaccination). Risk ratios (RR) between 2020-22/2023-25 and 2016-19 were calculated by age group and sex through Poisson regression models.</p><p><strong>Results: </strong>Annual Cuml remained stable (500 cases and 13 hospital admissions per 100,000 inhabitants), being higher among women. HZ cases had a high prevalence of hypertension (26.5%), diabetes (9.0%) and cardiovascular disease (6.6%). Incidence decreased between 2016-19/2023-25, especially in men, in age-groups under 15 y/o (RR=0.40; 95% CI: 0.33-0.48), 15-29 y/o (RR=0.74; 95% CI: 0.70-0.78), and 65-80 y/o (RR=0.81; 95% CI: 0.78-0.84), but it increased between 30 and 49 y/o, especially among women (RR=1.17; 95% CI: 1.15-1.20). Concerning hospital admissions, incidence decreased, especially in men, among 50-64 y/o (RR=0.82; 95% CI: 0.63-0.99), 65-80 y/o (RR=0.69; 95% CI: 0.57-0.81) and +80 y/o (RR=0.80; 95% CI: 0.67-0.93). The incidence decline was more evident in age groups eligible for vaccination since 2023.</p><p><strong>Conclusions: </strong>Recent variations in HZ incidence within age groups are observed. Strengthening epidemiological surveillance and evaluating vaccination impact remain essential.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503295"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Costal abscess caused by Salmonella serogroup O:9 in an immunocompetent adult: A case report.","authors":"Eva Soria Alcaide, Cristina Marcelo-Calvo, Ramón Puchades-Rincón Del Arellano, Beatriz Díaz-Pollán","doi":"10.1016/j.eimce.2026.503296","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503296","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503296"},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}