Enfermedades infecciosas y microbiologia clinica (English ed.)最新文献

Experience in the Canary Islands of an HIV screening strategy in hospital emergency departments: Results of the "Deja tu huella" program.

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-03 DOI: 10.1016/j.eimce.2025.02.011

Nayra Cabrera-González, José M Pavón-Monzó, Araceli Hernández-Betancor, Isidro Báez-Ramos

引用次数: 0

Detection and analysis of an Achromobacter xylosoxidans outbreak in a urodynamics unit.

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-03 DOI: 10.1016/j.eimce.2025.02.006

Simón Juárez Zapata, Carla Benjumea Moreno, Charo Porrón, Carles Alonso-Tarrés

{"title":"Detection and analysis of an Achromobacter xylosoxidans outbreak in a urodynamics unit.","authors":"Simón Juárez Zapata, Carla Benjumea Moreno, Charo Porrón, Carles Alonso-Tarrés","doi":"10.1016/j.eimce.2025.02.006","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.02.006","url":null,"abstract":"<p><strong>Introduction: </strong>Achromobacter xylosoxidans is a gramnegative bacillus resistant to multiple antibiotics, present both in the environment and in hospitals. This study describes an outbreak of colonizations and infections by A. xylosoxidans in the urodynamics unit of the Puigvert Foundation.</p><p><strong>Methods: </strong>On November 11, 2022, a patient developed a fever, and A. xylosoxidans was detected in their urine and blood. The case was linked to a recent urodynamic study. As a result, all A. xylosoxidans cases since 2018 were reviewed, and inspections were conducted in the unit, along with the collection of 24 environmental samples.</p><p><strong>Results: </strong>The review identified 21 patients with A. xylosoxidans infections after urodynamic procedures since April 2022. Environmental microbiological controls revealed that pressure transducers were the likely source of infection. Corrective measures included the temporary closure of the unit, thorough cleaning with hypochlorite, use of single-use urinary catheters, daily replacement of equipment lines and pressure transducers, as well as other improvements in disinfection, handling, and workflows. A multidisciplinary team was formed to implement and supervise these actions.</p><p><strong>Conclusions: </strong>The measures resulted in the elimination of the outbreak and the safe resumption of activities in the unit. This incident highlights the importance of continuous surveillance and rapid response in clinical settings to prevent infections and improve patient safety.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe invasive pulmonary aspergillosis caused by 2 different species of Aspergillus.

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-03 DOI: 10.1016/j.eimce.2025.02.007

Javier Romero López, José María García de Lomas Guerrero, Jesús Lancha Domínguez, Francisco Javier Martínez Marcos

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Efficacy of benznidazole treatment in advanced chronic digestive Chagas disease.

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-03 DOI: 10.1016/j.eimce.2025.02.009

Marta Díaz-Menéndez, Rosa de Miguel Buckley, Fernando de la Calle-Prieto, Marta Arsuaga

引用次数: 0

Invasive aspergillosis secondary to corticosteroid therapy.

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-03 DOI: 10.1016/j.eimce.2025.02.010

Sara Miguel Álvarez, Maravillas Carralón González, Juncal Pérez Somarriba, Vicente Estrada Pérez

引用次数: 0

Human subcutaneous dirofilariasis: A case report.

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-03 DOI: 10.1016/j.eimce.2025.02.008

Diana Nuevo-Silva, Elena M Garijo-Plano, Macarena Pariente-Martín, Juan J Camarena-Miñana

引用次数: 0

Effectiveness of Mycobacterium tuberculosis recombinant proteins-coated gold nanoparticles in improving the interferon-gamma release assay test

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-01 DOI: 10.1016/j.eimce.2024.06.011

Najmeh Jomehpour , Mojtaba Sankian , Saman Soleimanpour , Mohammad Derakhshan , Kiarash Ghazvini , Safora Pordel , Malihe Moghadam

{"title":"Effectiveness of Mycobacterium tuberculosis recombinant proteins-coated gold nanoparticles in improving the interferon-gamma release assay test","authors":"Najmeh Jomehpour , Mojtaba Sankian , Saman Soleimanpour , Mohammad Derakhshan , Kiarash Ghazvini , Safora Pordel , Malihe Moghadam","doi":"10.1016/j.eimce.2024.06.011","DOIUrl":"10.1016/j.eimce.2024.06.011","url":null,"abstract":"<div><h3>Introduction</h3><div>Gold nanoparticles (GNPs) are chemically inert, have low toxicity, and are easy to modify and functionalize for the detection of many pathogens. They have excellent immune modulatory and adjuvant properties. The aim of this study was to improve the diagnosis of latent tuberculosis infection (LTBI) by adding GNPs in tests based on interferon-gamma (IFN-γ) measurement.</div></div><div><h3>Methods</h3><div>GNPs were coated with <em>Mycobacterium tuberculosis</em> (Mtb) recombinant proteins including TB10.4, CFP-10, ESAT-6, and TB7.7. Then, they exposed the whole blood of subjects with active tuberculosis (aTB), LTBI, and healthy controls (HC). Subsequently, IFN-γ produced in GNP tubes (QFT-NG) was measured and compared with IFN-γ produced in tubes without GNPs [QFT-A: (CFP-10, ESAT-6, TB7.7, TB10.4), QFT-B: (CFP-10, ESAT-6, TB7.7)].</div></div><div><h3>Results</h3><div>The results showed that the IFN-γ production in the GNPs tubes was significantly higher than in tubes without GNPs in aTB, LTBI, and HC subjects. In aTB patients, the mean difference (MD) between the QFT-NG and QFT-A tubes was 0.44, with a <em>P</em>-value of 0.04, and a 95% CI: 0.07–0.88. Furthermore, in LTBI individuals, the QFT-NG and QFT-A tubes exhibited an MD=0.21, <em>P</em>-value=0.03, 95% CI: 0.15–0.4. In the aTB and LTBI subjects were detected in the QFT-NG tubes with a sensitivity of 95%, 100% and specificity 100%, 86%, respectively.</div></div><div><h3>Conclusion</h3><div>The use of GNPs coated with Mtb recombinant proteins can aid in detecting LTBI subjects by increasing IFN-γ levels.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 3","pages":"Pages 148-155"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis of Carrion's disease: A systematic review in South American countries and meta-analysis

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-01 DOI: 10.1016/j.eimce.2024.11.004

Mauro A.F. Guimarães , Laura A. Xavier , Alice F. Silva , Felipe C.M. Iani , Cecília M.M. Anjos , Cristiane F.O. Scarponi

{"title":"Diagnosis of Carrion's disease: A systematic review in South American countries and meta-analysis","authors":"Mauro A.F. Guimarães , Laura A. Xavier , Alice F. Silva , Felipe C.M. Iani , Cecília M.M. Anjos , Cristiane F.O. Scarponi","doi":"10.1016/j.eimce.2024.11.004","DOIUrl":"10.1016/j.eimce.2024.11.004","url":null,"abstract":"<div><div><em>Bartonella bacilliformis</em> can cause a potentially fatal infection, Carrion's disease. This review synthesized data on the prevalence of this bacterial infection in South American countries. A comprehensive literature search relevant articles (published between 2010 and 2022) was conducted in four databases. Full texts were selected based on PECOTS eligibility and JBI methodological quality. The pooled bacterial infection rate was calculated using a random-effects meta-analysis model. Subgroup and meta-regression analyses were used to investigate statistical heterogeneity. Five studies (covering 717 individuals from Peru and Ecuador) were eligible for meta-analysis. The percentage of seropositive IgG antibodies against <em>B. bacilliformis</em> was 28.21% (95% CI: 6.29–33.39) among healthy Ecuadorian children. In Peru, the pooled bacterial detection rate in symptomatic individuals was 15.60% (95% CI: 4.24–31.98), using molecular tests. Carrion's disease is endemic in the Andean valleys, but a gradual reduction in infection rates among acute febrile patients in Peru has been observed in recent years. Laboratory diagnosis of this infection continues to be neglected in other South American countries. Public managers must plan effective arrangements in primary care services, integrating various technological levels to ensure comprehensive health care.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 3","pages":"Pages 165-171"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Complicated malaria caused by Plasmodium falciparum with parasitemia >50%

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-01 DOI: 10.1016/j.eimce.2024.07.010

Miguel Morante-Ruiz, Cristina Ortega-Portas, Luis José Betancourt-Cuadra, Miguel Górgolas Hernández-Mora

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Lung cancer screening in people with HIV: A missed opportunity for better outcomes?

Enfermedades infecciosas y microbiologia clinica (English ed.) Pub Date : 2025-03-01 DOI: 10.1016/j.eimce.2024.12.009

Mar Masiá , Félix Gutiérrez

引用次数: 0