Electroencephalography and clinical neurophysiology最新文献_第10页

The organization of the cortical motor system: new concepts 皮层运动系统的组织:新概念

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(98)00022-4

G Rizzolatti, G Luppino, M Matelli

{"title":"The organization of the cortical motor system: new concepts","authors":"G Rizzolatti, G Luppino, M Matelli","doi":"10.1016/S0013-4694(98)00022-4","DOIUrl":"10.1016/S0013-4694(98)00022-4","url":null,"abstract":"<div><p>A series of recent anatomical and functional data has radically changed our view on the organization of the motor cortex in primates. In the present article we present this view and discuss its fundamental principles. The basic principles are the following: (a) the motor cortex, defined as the agranular frontal cortex, is formed by a mosaic of separate areas, each of which contains an independent body movement representation, (b) each motor area plays a specific role in motor control, based on the specificity of its cortical afferents and descending projections, (c) in analogy to the motor cortex, the posterior parietal cortex is formed by a multiplicity of areas, each of which is involved in the analysis of particular aspects of sensory information. There are no such things as multipurpose areas for space or body schema and (d) the parieto-frontal connections form a series of segregated anatomical circuits devoted to specific sensorimotor transformations. These circuits transform sensory information into action. They represent the basic functional units of the motor system. Although these conclusions mostly derive from monkey experiments, anatomical and brain-imaging evidence suggest that the organization of human motor cortex is based on the same principles. Possible homologies between the motor cortices of humans and non-human primates are discussed.</p></div>","PeriodicalId":72888,"journal":{"name":"Electroencephalography and clinical neurophysiology","volume":"106 4","pages":"Pages 283-296"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0013-4694(98)00022-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20655961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1126

A study of dipole localization accuracy for MEG and EEG using a human skull phantom 基于颅骨幻像的脑电与脑电偶极子定位精度研究

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(98)00057-1

R.M Leahy , J.C Mosher , M.E Spencer , M.X Huang , J.D Lewine

{"title":"A study of dipole localization accuracy for MEG and EEG using a human skull phantom","authors":"R.M Leahy , J.C Mosher , M.E Spencer , M.X Huang , J.D Lewine","doi":"10.1016/S0013-4694(98)00057-1","DOIUrl":"10.1016/S0013-4694(98)00057-1","url":null,"abstract":"<div><p><strong>Objective:</strong> To investigate the accuracy of forward and inverse techniques for EEG and MEG dipole localization.</p><p><strong>Design and Methods:</strong> A human skull phantom was constructed with brain, skull and scalp layers and realistic relative conductivities. Thirty two independent current dipoles were distributed within the `brain' region and EEG and MEG data collected separately for each dipole. The true dipole locations and orientations and the morphology of the brain, skull and scalp layers were extracted from X-ray CT data. The location of each dipole was estimated from the EEG and MEG data using the R-MUSIC inverse method and forward models based on spherical and realistic head geometries. Additional computer simulations were performed to investigate the factors affecting localization accuracy.</p><p><strong>Results:</strong> Localization errors using the relatively simpler locally fitted sphere approach are only slightly greater than those using a BEM approach. The average localization error over the 32 dipoles was 7–8 mm for EEG and 3 mm for MEG.</p><p><strong>Conclusion:</strong> The superior performance of MEG over EEG appears to be because the latter is more sensitive to errors in the forward model arising from simplifying assumptions concerning the conductivity of the skull, scalp and brain.</p></div>","PeriodicalId":72888,"journal":{"name":"Electroencephalography and clinical neurophysiology","volume":"107 2","pages":"Pages 159-173"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0013-4694(98)00057-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20665361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Usefulness of latero-orbital electrodes in detecting interictal epileptiform activity – a study of 60 patients with complex partial seizures1 后眼窝电极检测间期癫痫样活动的有效性——对60例复杂部分性癫痫患者的研究1

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(98)00049-2

Antonio Gambardella, Franco Pucci, Emilio Le Piane, Demetrio Messina, Concetta Russo, Mario Zappia, R Luciano Oliveri, Aldo Quattrone, Umberto Aguglia

{"title":"Usefulness of latero-orbital electrodes in detecting interictal epileptiform activity – a study of 60 patients with complex partial seizures1","authors":"Antonio Gambardella, Franco Pucci, Emilio Le Piane, Demetrio Messina, Concetta Russo, Mario Zappia, R Luciano Oliveri, Aldo Quattrone, Umberto Aguglia","doi":"10.1016/S0013-4694(98)00049-2","DOIUrl":"10.1016/S0013-4694(98)00049-2","url":null,"abstract":"<div><p><strong>Objectives</strong>: The use of latero-orbital (Lo) electrodes is a routine practice in any EEG laboratory to evaluate eye motion, but there are no data about their usefulness in revealing interictal epileptiform abnormalities.</p><p><strong>Methods</strong>: In 60 consecutive patients (27 men, 33 women, mean age 36 8 years, range 17–72) with complex partial seizures, we prospectively evaluated the utility of Lo electrodes in comparison with anterior temporal (AT) electrodes, for the detection of interictal epileptiform discharges (SW).</p><p><strong>Results</strong>: No epileptiform abnormality was seen in 4/60 patients. Both AT and Lo electrodes were significantly superior to 10–20 electrodes for detection of both patients and foci. Indeed, the standard 10–20 system alone allowed the detection of only 39 independent epileptiform foci in 35/56 (63%) patients, while AT and Lo electrodes were necessary for detection of 23 epileptiform foci in the remaining 21/56 (37%) patients. Importantly, there was no statistically significant difference in detection between AT and Lo electrodes.</p><p><strong>Conclusions</strong>: Recordings from Lo electrodes are comparable to those from AT electrodes and are useful for localizing interictal temporal spiking activity. Lo electrodes may be substituted for basal electrodes in the day-to-day evaluation of patients with complex partial seizures.</p></div>","PeriodicalId":72888,"journal":{"name":"Electroencephalography and clinical neurophysiology","volume":"107 2","pages":"Pages 174-176"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0013-4694(98)00049-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20665362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Dipole source localization by means of maximum likelihood estimation. I. Theory and simulations 用极大似然估计方法进行偶极子源定位。一、理论与仿真

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(97)00140-5

B Lütkenhöner

引用次数: 35

Localisation of epileptic foci with electric, magnetic and combined electromagnetic models 用电、磁和电磁组合模型定位癫痫病灶

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(97)00142-9

V. Diekmann , W. Becker , R. Jürgens , B. Grözinger , B. Kleiser , H.P. Richter , K.H. Wollinsky

{"title":"Localisation of epileptic foci with electric, magnetic and combined electromagnetic models","authors":"V. Diekmann , W. Becker , R. Jürgens , B. Grözinger , B. Kleiser , H.P. Richter , K.H. Wollinsky","doi":"10.1016/S0013-4694(97)00142-9","DOIUrl":"10.1016/S0013-4694(97)00142-9","url":null,"abstract":"<div><p>We compare the localisation of epileptic foci by means of (1) EEG, (2) magnetoencephalography (MEG) and (3) combined EEG/MEG data in a group of patients suffering from pharmaco-resistant focal epilepsy. Individual epileptic events were localised by means of a moving dipole model in a 4-shell spherical head approximation. A patient's epileptic activity was summarised by calculating the spatial density distribution (DD) of all localised events, and the centre of gravity of DD was considered the most likely locus of seizure generation. To verify these loci a subgroup of 6 patients was selected, in which seizures could be related to a clearly identifiable lesion in MRI. On average, the combined EEG/MEG approach resulted in the smallest error (1.8 cm distance between calculated locus and the nearest lesion border); using only MEG yielded the largest error (2.4 cm), while EEG resulted in an intermediate value (2.2 cm). In the individual patients, EEG/MEG would also rank intermediate, but never worst. In summary, combining EEG/MEG appears to be a more robust approach to localisation than using only EEG or only MEG. Finally, we also report on the use of the barbiturate methohexital as a safe method of increasing the number of spike events during an EEG/MEG recording session.</p></div>","PeriodicalId":72888,"journal":{"name":"Electroencephalography and clinical neurophysiology","volume":"106 4","pages":"Pages 297-313"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0013-4694(97)00142-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20655278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 68

In the footsteps of Beck: the desynchronization of the electroencephalogram 跟随贝克的脚步:脑电图的非同步化

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(97)00126-0

Anton Coenen , Oksana Zajachkivsky , Ryszard Bilski

引用次数: 11

Improving source reconstructions by combining bioelectric and biomagnetic data 结合生物电和生物磁数据改进震源重建

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(98)00046-7

Manfred Fuchs , Michael Wagner , Hans-Aloys Wischmann , Thomas Köhler , Annette Theißen , Ralf Drenckhahn , Helmut Buchner

{"title":"Improving source reconstructions by combining bioelectric and biomagnetic data","authors":"Manfred Fuchs , Michael Wagner , Hans-Aloys Wischmann , Thomas Köhler , Annette Theißen , Ralf Drenckhahn , Helmut Buchner","doi":"10.1016/S0013-4694(98)00046-7","DOIUrl":"10.1016/S0013-4694(98)00046-7","url":null,"abstract":"<div><p><strong>Objectives</strong>: A framework for combining bioelectric and biomagnetic data is presented. The data are transformed to signal-to-noise ratios and reconstruction algorithms utilizing a new regularization approach are introduced.</p><p><strong>Methods</strong>: Extensive simulations are carried out for 19 different EEG and MEG montages with radial and tangential test dipoles at different eccentricities and noise levels. The methods are verified by real SEP/SEF measurements. A common realistic volume conductor is used and the less-well-known in-vivo conductivities are matched by calibration to the magnetic data. Single equivalent dipole fits as well as spatiotemporal source models are presented for single and combined modality evaluations and overlaid to anatomic MR images.</p><p><strong>Results</strong>: Normalized sensitivity and dipole resolution profiles of these acquisition systems are derived from these synthetic data. The methods are verified by simultaneously measured somasensory data.</p><p><strong>Conclusions</strong>: Superior spatial resolution of the combined data studies is revealed, which is due to the complementary nature of both modalities and the increased number of sensors. a better understanding of the underlying neironal processes can be acheived, since an improved differentiation between quasi-tangential and quasi-radial sources is possible.</p></div>","PeriodicalId":72888,"journal":{"name":"Electroencephalography and clinical neurophysiology","volume":"107 2","pages":"Pages 93-111"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0013-4694(98)00046-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20664198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 232

Abstract 摘要

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(98)00010-8

引用次数: 0

Segmentation and classification of EEG during epileptic seizures 癫痫发作时脑电图的分割与分类

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(97)00156-9

L Wu, J Gotman

引用次数: 32

Does pattern electroretinogram spatial tuning alteration in Parkinson's disease depend on motor disturbances or retinal dopaminergic loss? 帕金森氏症视网膜电图空间调谐模式改变是否依赖于运动障碍或视网膜多巴胺能丧失?

Electroencephalography and clinical neurophysiology Pub Date : 1998-04-01 DOI: 10.1016/S0013-4694(97)00075-8

A Peppe , P Stanzione , M Pierantozzi , R Semprini , A Bassi , A.M Santilli , R Formisano , M Piccolino , G Bernardi

{"title":"Does pattern electroretinogram spatial tuning alteration in Parkinson's disease depend on motor disturbances or retinal dopaminergic loss?","authors":"A Peppe , P Stanzione , M Pierantozzi , R Semprini , A Bassi , A.M Santilli , R Formisano , M Piccolino , G Bernardi","doi":"10.1016/S0013-4694(97)00075-8","DOIUrl":"10.1016/S0013-4694(97)00075-8","url":null,"abstract":"<div><p>Systemic decrease of dopaminergic cells, such as in Parkinson's disease may produce visual alterations in humans. In order to show possible pattern electroretinogram (PERG) spatial tuning function (STF) alterations due to impaired dopaminergic transmission in humans, we studied a group of Parkinson's disease patients before and during treatment with the dopamine precursor, levodopa, and compared their performances with those of an age-matched control group. Moreover, in order to exclude the possible involvement of motor disabilities to produce PERG alterations, we also investigated PERG responses in post-traumatic parkinsonian patients who exhibited motor abnormalities as a consequence of focal lesions of basal ganglia, in the absence of systemic dopaminergic degeneration. Our results showed a clear decrease of PERG responses in Parkinson's disease patients particularly at medium spatial frequency range (2.7–4.0 cycles/degree) with a substantial preservation of responses at low frequencies. Levodopa therapy reversed these alterations in Parkinson's disease patients, resulting in the recovery of a normal tuning function shape. In contrast to Parkinson's disease, the tuning function appeared to be preserved in post-traumatic parkinsonian patients. Our results clearly establish a relationship between retinal alteration in PD patients and dopaminergic retinal function.</p></div>","PeriodicalId":72888,"journal":{"name":"Electroencephalography and clinical neurophysiology","volume":"106 4","pages":"Pages 374-382"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0013-4694(97)00075-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20655286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 61