Kevin Wenzel , Julia Thomas , Jennifer Carrano , Jennifer Stidham , Marc Fishman
{"title":"Exploring the impact of a medication adherence intervention on recovery and mental health outcomes: A secondary analysis of the MAT-PLUS pilot RCT","authors":"Kevin Wenzel , Julia Thomas , Jennifer Carrano , Jennifer Stidham , Marc Fishman","doi":"10.1016/j.dadr.2025.100346","DOIUrl":"10.1016/j.dadr.2025.100346","url":null,"abstract":"<div><h3>Background</h3><div>Substance use disorders (SUDs) including opioid use disorder (OUD) and alcohol use disorder (AUD) contribute to significant morbidity and mortality in the United States. Pharmacotherapy treatment, including extended-release naltrexone (XR-NTX), is underutilized in large part due to poor treatment retention. The MAT-PLUS (Medication Adherence Therapy: Psychosocial Leverage Using a Significant other) intervention combines assertive outreach, significant other involvement, and low-barrier access to medicine to improve retention on XR-NTX, and has shown promising results in a pilot RCT. <em>Methods:</em> This report explored secondary outcomes from the MAT-PLUS pilot RCT (NCT03567356) to determine the impact of the intervention on recovery experience as measured by the Recovery Assessment Scale (RAS) and mental health indicators as measured by the patient health questionnaire- somatic, anxiety, depression scale (PHQ-SADS) on <em>N</em> = 41 participants. <em>Results:</em> A series of repeated measures mixed ANOVAs did not find evidence of an effect of the MAT-PLUS intervention on these outcomes. Although total RAS scores did not improve over time in either condition, an independent samples t-test at the post-intervention follow up suggested some evidence of a possible treatment effect on two subscales of the RAS: 1) Not being dominated by symptoms and 2) Goal and success orientation. <em>Discussion:</em> The results of this study suggest that mental health symptoms are attenuated during treatment, whether usual care or the MAT-PLUS intervention, but that recovery indicators did not improve with treatment. Approaches to SUD care, including the MAT-PLUS intervention, should be refined to target improvements in recovery capital in addition to focusing on symptom reduction.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100346"},"PeriodicalIF":0.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144124190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina S. Lee , Erika G. Cordova-Ramos , Damaris J. Rohsenow , Kim T. Mueser , Christine A. Pace , Rosemarie Martin , Suzanne M. Colby , Victoria Lopez , Melanie Morris , Jake R. Morgan , Ari Kriegsman , Mari-Lynn Drainoni
{"title":"Care management staff perspectives on stigma and barriers to substance use treatment experienced by latine adults who use substances","authors":"Christina S. Lee , Erika G. Cordova-Ramos , Damaris J. Rohsenow , Kim T. Mueser , Christine A. Pace , Rosemarie Martin , Suzanne M. Colby , Victoria Lopez , Melanie Morris , Jake R. Morgan , Ari Kriegsman , Mari-Lynn Drainoni","doi":"10.1016/j.dadr.2025.100342","DOIUrl":"10.1016/j.dadr.2025.100342","url":null,"abstract":"<div><h3>Background</h3><div>Stigma related to substance use or addiction contributes to health care inequality. Structural stigma - embedded in societal conditions, policies, practices, and cultural norms - has been less studied than interpersonal (e.g., provider bias) and individual level stigma processes. The perspectives of staff working with patients who navigate health care systems can help to identify substance use stigma at the structural and interpersonal levels. The study aimed to examine staff perceptions of structural and interpersonal stigma processes, their association with barriers to substance use disorder (SUD) care, the interplay between different levels of stigma, and their impacts at the individual level.</div></div><div><h3>Methods</h3><div>Care management staff (n = 20, 75 % community health workers, CHWs) from a complex care management program were interviewed about the challenges Latine compared to non-Latine patients faced in accessing care for substance use treatment. Thematic analysis was used to analyze interview transcripts. The Structural Stigma framework was used to guide analysis.</div></div><div><h3>Results</h3><div>Structural and interpersonal stigma processes as well as intersectional stigma were associated with barriers to SUD care. Latine patients were reported as being frequently affected by intersecting systems of oppression due to multiple stigmatized identities (e.g., persons with substance use and as immigrants) than non-Latine patients. Structural and interpersonal stigma processes were associated with self-stigma and hindered help-seeking behaviors.</div></div><div><h3>Conclusion</h3><div>Care management staff offer unique perspectives into how stigma at multiple levels is experienced by patients and perpetuated. Stigma processes may discourage the initiation of needed substance use care among Latine persons experiencing oppression.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100342"},"PeriodicalIF":0.0,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144115368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samuel J. Chen , Harold A. Pollack , Elizabeth M. Salisbury-Afshar , Mai T. Pho
{"title":"Access to and predictors of substance use treatment and support among people experiencing incarceration in the United States: Analysis of a national cross-sectional study","authors":"Samuel J. Chen , Harold A. Pollack , Elizabeth M. Salisbury-Afshar , Mai T. Pho","doi":"10.1016/j.dadr.2025.100343","DOIUrl":"10.1016/j.dadr.2025.100343","url":null,"abstract":"<div><div>Substance use-related overdose continues to be one of the leading causes of preventable death in the U.S. People returning from prisons and jails are at heightened risk. Certain substance use treatment methods in carceral facilities – especially medication for opioid use disorder (MOUD) – have shown promise in reducing overdose rates. Treatment availability has been under-studied, with past research often measuring whether facilities offer treatment, but not whether individuals actually receive it. This study used individual-level data to characterize who qualifies for prison-based treatment, who receives it, and what factors affect one’s likelihood of being treated, drawing from the most recent nationally-representative U.S. Survey of Prison Inmates. Descriptive statistics indicate that people with substance use disorder (SUD) who entered American prisons from 2014 to 2016 had lower levels of educational attainment, employment and housing, and higher levels of physical and mental illness. Just 13 % of individuals with SUD received any form of substance use treatment in prison; pharmacotherapies like methadone were almost nonexistent (<1 %). In controlled analysis, individuals who self-identified as Non-Hispanic Black or Hispanic had lower odds of receiving any treatment or support compared to Non-Hispanic White individuals. People convicted of a violent offense had lower odds of treatment than those convicted of other classes of crimes. These novel findings indicate that, in 2016, America’s prison-based substance use treatment had both poor accessibility and inequitable distribution. This raises concerns that, even as facility-level availability of modalities like MOUD continues to expand, certain groups may be left out without attention to individual-level availability.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100343"},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144068551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felipe I. Varas , Gonzalo Miguez , Vanetza E. Quezada-Scholz , Esperanza Ibáñez-Jiménez , Camila Aguilar , Simón Ramírez , Jonathan Badilla , Felipe Alfaro , Francisca Bertin , Javier Bustamante , Rocío Angulo , José A. Fuentealba , Alvaro Vergés , Mario A. Laborda
{"title":"Assessment of the associative determinants of tolerance to the effects of cannabis extract on exploratory behavior in rats","authors":"Felipe I. Varas , Gonzalo Miguez , Vanetza E. Quezada-Scholz , Esperanza Ibáñez-Jiménez , Camila Aguilar , Simón Ramírez , Jonathan Badilla , Felipe Alfaro , Francisca Bertin , Javier Bustamante , Rocío Angulo , José A. Fuentealba , Alvaro Vergés , Mario A. Laborda","doi":"10.1016/j.dadr.2025.100344","DOIUrl":"10.1016/j.dadr.2025.100344","url":null,"abstract":"<div><div>Experimental evaluation of cannabis tolerance has lacked an associative learning approach, focusing primarily on physiological variables. The present study assessed acute effects, chronic tolerance, and contextual specificity, exploring a potential associative component underlying cannabis tolerance. Sixteen adult Sprague-Dawley rats of both sexes were assigned to two groups, one receiving vaporized administrations of cannabis and the other receiving the vehicle substance, in two different counterbalanced contexts. An initial measurement was performed to assess acute effects, followed by four measurements to evaluate the development of chronic tolerance, and a final measurement to test the context specificity of tolerance, comparing the responses to the usual administration context and a novel context. Ten behaviors were analyzed in an open field. Acute effects were observed in seven indicators, corresponding to greater exploration activity in the group that received the drug compared to the control group. In five of these, the data also showed the development of chronic tolerance to the effects of cannabis on exploration, which was indicated by a progressive decrease in exploratory activity in the drug group. However, no evidence of context specificity was found in any variables in which chronic tolerance was observed. We discuss factors that may be related to the lack of contextual specificity of cannabis tolerance. Together, our findings show that a single administration of cannabis induces acute effects, and repeated exposure leads to chronic tolerance, ultimately reducing exploratory behavior.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100344"},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143948267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kevin Frederiks , Maxwell Everett , Kristen Gilmore Powell , N. Andrew Peterson , Suzanne Borys , Donald K. Hallcom , Nina A. Cooperman
{"title":"Reported outcomes from a community naloxone training and distribution program","authors":"Kevin Frederiks , Maxwell Everett , Kristen Gilmore Powell , N. Andrew Peterson , Suzanne Borys , Donald K. Hallcom , Nina A. Cooperman","doi":"10.1016/j.dadr.2025.100341","DOIUrl":"10.1016/j.dadr.2025.100341","url":null,"abstract":"<div><div>The United States opioid epidemic is an enormous public health crisis, claiming over 500,000 lives between 1999 and 2020. However, the increased availability of naloxone has saved many lives and led to the development of community-based naloxone training and distribution programs. We developed a naloxone education and distribution program in New Jersey in 2017. This program provides a 60-minute training for community members in various settings, such as police departments, community centers, etc. Participants were instructed to call the training and distribution program if they used their naloxone kit, and the program would replace it. Callers were asked a short survey about behaviors during the naloxone administration and overdose outcome. From January 2018 through June 2022, 191 calls to report an overdose and request a new kit were received. Overall, 70 (37 %) of the reported naloxone administrations were by police, 38 (20 %) family/friends, and 50 (26 %) strangers. The most common actions taken during the overdose included: 162 (85 %) calling EMS; 161 (84 %) staying with the person who overdosed until EMS arrived; and 131 (69 %) checking the individual who overdosed for signs of breathing. Individuals who helped with an overdose were able to revive the person in 172 (90 %) of the reported overdoses. Our data suggests that participants in these programs will use naloxone for opioid overdoses whether the victim is known to the participant or a stranger. Future research should focus on understanding outcomes of and behaviors during overdose episodes that are not reported to the program.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100341"},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitra Kale , Vera Buss , Melissa Oldham , Jamie Brown , Lion Shahab , Sarah Jackson
{"title":"Trends in motives for attempts to reduce alcohol consumption among risky adult drinkers in England: A representative population survey, 2017–2024","authors":"Dimitra Kale , Vera Buss , Melissa Oldham , Jamie Brown , Lion Shahab , Sarah Jackson","doi":"10.1016/j.dadr.2025.100340","DOIUrl":"10.1016/j.dadr.2025.100340","url":null,"abstract":"<div><h3>Background</h3><div>Understanding the motives for reducing alcohol consumption, how they differ among various population groups, and how they have evolved over time is crucial for designing effective public health interventions. This study estimated time trends in motives for attempts to reduce alcohol consumption among risky adult drinkers in England between 2017 and 2024 and explored differences by sociodemographics and alcohol consumption levels.</div></div><div><h3>Methods</h3><div>Data came from a nationally representative survey (Alcohol Toolkit Study), assessing 11,974 risky adult drinkers (mean [Standard Deviation] age= 45.8 [15.7] years, 60.1 % men) who made a past-year reduction attempt between January/2017 and August/2024. Participants reported factors motivating their most recent attempt (not mutually exclusive). We estimated time trends in the proportion of attempts to reduce alcohol consumption motivated by health concerns, cost, social factors (i.e., peer influence/support) and health professional advice, and calculated prevalence ratios (PRs) to compare changes in prevalence across the whole time series.</div></div><div><h3>Results</h3><div>Over the time series, there was a small increase in the proportion of attempts motivated by health concerns (70.5–76.8 %; PR=1.09, 95 %CI1.01–1.18). Attempts motivated by cost and social factors nearly doubled (10.7–20.2 %; PR=1.89, 95 %CI1.37–2.60; 13.3–25.5 %; PR=1.92, 95 %CI1.46–2.52, respectively). Attempts driven by health professional advice increased (4.4–7.0 %; PR=1.57, 95 %CI0.96–2.57). Women, individuals from less advantaged social grades and with AUDIT-C 5–7 exhibited more pronounced changes in the proportion of attempts motivated by health concerns. Cost was a more consistent driver of attempts for those aged≥ 65.</div></div><div><h3>Conclusions</h3><div>Health concerns remain the most common motive for attempts to reduce alcohol consumption, but the proportion of attempts motivated by cost and social factors nearly doubled over the study period. These findings suggest the need for public health interventions that consider both economic and social influences alongside health concerns to better support alcohol reduction.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100340"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rebecca Arden Harris , Judith A. Long , Yuhua Bao , Henry R. Kranzler , Jeanmarie Perrone , David S. Mandell
{"title":"Methadone-involved overdose deaths in urban and rural communities before and after the public health emergency flexibilities for methadone take-home doses","authors":"Rebecca Arden Harris , Judith A. Long , Yuhua Bao , Henry R. Kranzler , Jeanmarie Perrone , David S. Mandell","doi":"10.1016/j.dadr.2025.100339","DOIUrl":"10.1016/j.dadr.2025.100339","url":null,"abstract":"<div><h3>Background</h3><div>To mitigate COVID-19 exposure risks in methadone clinics, the Substance Abuse and Mental Health Services Administration (SAMHSA) issued a temporary modification of regulations in March 2020 to permit extended take-home methadone doses: up to 28 days of take-home methadone for stable patients and 14 days for those less stable. This study examined the association between the policy change and fatal methadone overdoses across the urban-rural continuum.</div></div><div><h3>Methods</h3><div>This interrupted time series analysis used the U.S. <span><span>National Vital Statistics System</span></span> (NVSS) 2018–2022 mortality data to examine monthly trends in methadone-involved overdose deaths before and after the policy change allowing more take-home methadone doses. Deaths were stratified into six urban-rural categories and by co-involvement of fentanyl.</div></div><div><h3>Results</h3><div>Prior to the policy change, trends in methadone-involved overdose deaths were either flat or declining across all urbanization categories. Following the policy change, deaths decreased significantly in Large Central Metro areas but increased in rural Micropolitan counties. No trend changes occurred in the other urban or rural categories. When stratified by fentanyl co-involvement, Large Central Metro areas experienced a decrease in methadone deaths with fentanyl, though not statistically significant, and a significant decrease without fentanyl. In rural Micropolitan counties, methadone deaths saw an increase with fentanyl co-involvement that did not reach significance, and a significant increase without fentanyl. Noncore counties saw a significant increase in deaths involving both methadone and fentanyl, with no notable change observed without fentanyl.</div></div><div><h3>Conclusions</h3><div>Results suggest the need to expand methadone access and treatment supports in underserved rural communities, recognizing that factors beyond the policy change may have contributed to the reported associations.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100339"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gillian Kolla , Kaitlin Fajber , Andrea Sereda , Cassidy Morris , Perri Deacon , Lauren E. Cipriano
{"title":"Opioid medication doses among safer supply clients: Current safer supply doses and previous OAT experience","authors":"Gillian Kolla , Kaitlin Fajber , Andrea Sereda , Cassidy Morris , Perri Deacon , Lauren E. Cipriano","doi":"10.1016/j.dadr.2025.100338","DOIUrl":"10.1016/j.dadr.2025.100338","url":null,"abstract":"<div><h3>Introduction</h3><div>Safer opioid supply (SOS) is a harm reduction approach to prescribing pharmaceutical opioids to people at high risk of overdose from the toxic unregulated drug supply. Previous research demonstrates positive health outcomes and reductions in overdose mortality among SOS clients; however few reports describe previous opioid agonist treatment history prior to initiating SOS, or the medication combinations and doses prescribed within SOS programs.</div></div><div><h3>Methods</h3><div>We used convenience sampling to collect survey data from 95 SOS program clients in London, Canada. We use descriptive statistics to analyze survey data and report on OAT history prior to initiating SOS, including maximum methadone dose. We also report on current SOS medication combinations and doses.</div></div><div><h3>Findings</h3><div>Previous experience with OAT was common and reported by 87 % of SOS clients. Mean highest dose of methadone ever received was 95<!--> <!-->mg (range: 20–200<!--> <!-->mg), with close to 40 % reporting doses of ≥ 120<!--> <!-->mg. 95 % of SOS clients reported prescriptions for immediate-release tablet hydromorphone; 28 % were receiving hydromorphone monotherapy; 68 % were receiving hydromorphone alongside a long-acting opioid, and 5 % receiving hydromorphone alongside 2 long-acting opioids. Total average milligram morphine equivalent (MME) doses of combination SOS prescriptions (MME 1616) were similar to high dose methadone (120<!--> <!-->mg = MME 1440).</div></div><div><h3>Conclusions</h3><div>Previous high dose OAT experience was common among SOS clients prior to enrollment in the SOS program. Our results may inform the individualization of high dose opioid prescriptions for people with high tolerance due to exposure to unregulated fentanyl.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100338"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143901915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joy D. Scheidell , Sophia Dakoulas , Teresa Chueng , Katrina Ciraldo , Belén Hervera , Muthoni Mahachi , Luther C. Elliott , Alex S. Bennet
{"title":"An exploratory study on the use of sexually transmitted infection prevention and contraception methods among women and men who use unprescribed opioids","authors":"Joy D. Scheidell , Sophia Dakoulas , Teresa Chueng , Katrina Ciraldo , Belén Hervera , Muthoni Mahachi , Luther C. Elliott , Alex S. Bennet","doi":"10.1016/j.dadr.2025.100337","DOIUrl":"10.1016/j.dadr.2025.100337","url":null,"abstract":"<div><h3>Introduction</h3><div>The dual epidemics of sexually transmitted infections (STIs) and unprescribed opioid use persist globally, including in the United States. This study addresses gaps in STI prevention and contraception among people who use unprescribed opioids in New York City (NYC), focusing on both men and women.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional substudy from November 2021-August 2022 assessing sexual health with a one-time survey within a longitudinal cohort study among people who use unprescribed opioids in NYC that collected baseline data during 2019–2020. We measured sociodemographic characteristics, substance use history, sexual partnerships and STI prevention and contraception categorized as providing effective prevention versus none/ineffective. We estimated the prevalence of lack of effective STI prevention and contraception and potential correlates among males and females.</div></div><div><h3>Results</h3><div>The analytic sample included 108 participants (54 % male, 46 % female) with a mean age of 46 years. No/ineffective STI prevention was most common among reproductive-age females (81 %) and lowest among males (67 %) and no/less effective contraception was reported by approximately 90 % of participants. No/ineffective STI prevention and contraception were differentially associated with factors such as sexual partnerships, substance use treatment, and healthcare utilization among males and females.</div></div><div><h3>Discussion</h3><div>Findings highlight the need for improved provision of effective STI and pregnancy prevention methods for both men and women who use drugs. There is a critical need to expand access to sexual and reproductive health services for people who use drugs, including integrating these services into diverse healthcare and drug-service settings.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100337"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Digital detection of craving and stress for individuals in recovery from substance use disorder: A qualitative study","authors":"Jazmin Hampton , Reynalde Eugene , Nirzari Kapadia , Emily Caggiano , Amanda Geagea , C. James Watson , Stephanie Carreiro","doi":"10.1016/j.dadr.2025.100336","DOIUrl":"10.1016/j.dadr.2025.100336","url":null,"abstract":"<div><h3>Aims</h3><div>This study aims to 1) categorize experiences with stress and craving during substance use disorder (SUD) treatment, 2) explore perceptions of both clients and treatment providers towards a digital detection system for stress and craving during recovery, and 3) identify barriers and facilitators to adopting this technology during SUD treatment.</div></div><div><h3>Methods</h3><div>This was a qualitative study of people in recovery from SUD (clients) and healthcare providers from outpatient treatment facilities in the northeast United States. Clients were asked to use a digital health tool that detects physiological biomarkers of stress and craving (RAE Health) for 30 days alongside their usual treatment and to engage in a semi-structured interview upon completion. Providers were asked to participate in a one-time focus group.</div></div><div><h3>Results</h3><div>Thirty-one clients completed a semi-structured interview, and eleven providers participated in two focus groups. Four core themes emerged from the qualitative data: categorization of experiences with stress and craving, perceptions of digital detection systems, perceived barriers and facilitators of the system, and desired features of the system. Overall, client and provider perception were positive, and acceptability of the digital health tool was high.</div></div><div><h3>Conclusions</h3><div>A digital detection system for stress and craving during SUD recovery was perceived favorably by both clients and providers, with clients citing heightened awareness and providers citing opportunities for personalized care as promising use cases. Future iterations of digital health systems for this population should consider the ideal “dose” of the intervention to maximize benefit.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"15 ","pages":"Article 100336"},"PeriodicalIF":0.0,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}