Discover nano最新文献

{"title":"A novel transdermal drug delivery system: drug-loaded ROS-responsive ferrocene fibers for effective photoprotective and wound healing activity.","authors":"Sangwoo Kim, Yoon Kim, Chaehyun Kim, Won Il Choi, Byoung Soo Kim, Jinkee Hong, Hoik Lee, Daekyung Sung","doi":"10.1186/s11671-024-04058-w","DOIUrl":"10.1186/s11671-024-04058-w","url":null,"abstract":"<p><p>The present study proposes an innovative transdermal drug delivery system using ferrocene-incorporated fibers to enhance the bioavailability and therapeutic efficacy of ascorbyl tetraisopalmitate. Using electrospinning technology, the authors created ferrocene polymer fibers capable of highly efficient drug encapsulation and controlled release in response to reactive oxygen species commonly found in wound sites. The approach improves upon previous methods significantly by offering higher drug loading capacities and sustained release, directly targeting diseased cells. The results confirm the potential of ferrocene fibers for localized drug delivery, potentially reducing side effects and increasing patient convenience. The method could facilitate the application of bioactive compounds in medical textiles and targeted therapy.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"119"},"PeriodicalIF":0.0,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11286613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploitation of functionalized green nanomaterials for plant disease management.","authors":"Dhiraj L Wasule, Prashant R Shingote, Shreshtha Saxena","doi":"10.1186/s11671-024-04063-z","DOIUrl":"10.1186/s11671-024-04063-z","url":null,"abstract":"<p><p>A crucial determining factor in agricultural productivity is biotic stress. In addition, supply of quality food to the ever-increasing world's population has raised the food demand tremendously. Therefore, enhanced agricultural crop productivity is the only option to mitigate these concerns. It ultimately demanded the often and indiscriminate use of synthetic agrochemicals such as chemical fertilizers, pesticides, insecticides, herbicides, etc. for the management of various biotic stresses including a variety of plant pathogens. However, the food chain and biosphere are severely impacted due to the use of such harmful agrochemicals and their byproducts. Hence, it is need of hour to search for novel, effective and ecofriendly approaches for the management of biotic stresses in crop plants. Particularly, in plant disease management, efforts are being made to take advantage of newly emerged science i.e. nanotechnology for the creation of inorganic nanoparticles (NPs) such as metallic, oxide, sulphide, etc. through different routes and their application in plant disease management. Among these, green nanomaterials which are synthesized using environmentally friendly methods and materials reported to possess unique properties (such as high surface area, adjustable size and shape, and specific functionalities) making them ideal candidates for targeted disease control. Nanotechnology can stop crop losses by managing specific diseases from soil, plants, and hydroponic systems. This review mainly focuses on the application of biologically produced green NPs in the treatment of plant diseases caused due to bacteria, viruses, and fungi. The utilization of green synthesis of NPs in the creation of intelligent targeted pesticide and biomolecule control delivery systems, for disease management is considered environmentally friendly due to its pursuit of less hazardous, sustainable, and environmentally friendly methods.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"118"},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11258113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial efficacy of nano-particles for crop protection and sustainable agriculture.","authors":"Pallavi Jali, Srinivas Acharya, Gyanranjan Mahalik","doi":"10.1186/s11671-024-04059-9","DOIUrl":"10.1186/s11671-024-04059-9","url":null,"abstract":"<p><p>Plant diseases cause colossal crop loss worldwide and are the major yield constraining component in agriculture. Nanotechnology, which has the possible to revolutionize numerous fields of science, innovation, drug, and agriculture. Nanotechnology can be utilized for combating the plant infectious diseases and nano-materials can be utilized as transporter of dynamic elements of pesticides, host defense etc. to the pathogens. The analysis of diseases, finding of pathogens may turn out to be substantially more precise and fast with the utilization of nanosensors. As worldwide demand for food production raises against an evolving atmosphere, nanotechnology could reasonably alleviate numerous challenges in disease managing by diminishing chemical inputs and advancing quick recognition of pathogens. The major goal of this review is to increase growth and productivity using supplements with nanoparticles. (i.e., metals, metal oxides, and carbon) to treat crop diseases and make agricultural practices more productive and sustainable. Prominently, this improved crop may not only be straight connected to the diminished occurrence of pathogenic microorganisms, yet in might possibly add nutritional benefits of the nanoparticles themselves, particularly for the micronutrients important for generating host resistance.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"117"},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11250757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of annealing temperature on the optoelectrical synapse behaviors of A-ZnO microtube.","authors":"Yongman Pan, Qiang Wang, Anqing He, Yinzhou Yan, Xingzhong Cao, Peng Liu, Yijian Jiang","doi":"10.1186/s11671-024-04060-2","DOIUrl":"10.1186/s11671-024-04060-2","url":null,"abstract":"<p><p>Optoelectronic synapses with fast response, low power consumption, and memory function hold great potential in the future of artificial intelligence technologies. Herein, a strategy of annealing in oxygen ambient at different temperatures is presented to improve the optoelectronic synaptic behaviors of acceptor-rich ZnO (A-ZnO) microtubes. The basic synaptic functions of as-grown and annealed A-ZnO microtubes including excitatory postsynaptic current (EPSC), short-term memory (STM) to long-term memory (LTM) conversion, and paired-pulse facilitation (PPF), were successfully emulated. The results show that the annealing temperature of 600 °C yields high figures of merit compared to other annealed A-ZnO microtubes. The 4-fold and 20-fold enhancement dependent on the light pulse duration time and energy density have been achieved in the 600 °C annealed A-ZnO microtube, respectively. Furthermore, the device exhibited a PPF index of up to 238% and achieved four cycles of \"learning-forgetting\" process, proving its capability for optical information storage. The free exciton (FX) and donor-acceptor pair (DAP) concentrations significantly influenced the persistent photoconductivity (PPC) behavior of A-ZnO microtubes. Therefore, the LTM response can be controlled by the adjustment of numbers, powers, and interval time of the optical stimulation. This work outlines a strategy to improve the EPSC response through defect control, representing a step towards applications in the field of optoelectronic synaptic device.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"116"},"PeriodicalIF":0.0,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11246399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticandidal applications of selenium nanoparticles biosynthesized with Limosilactobacillus fermentum (OR553490).","authors":"Esraa Ali Mohamed, Mohamed Marzouk El-Zahed","doi":"10.1186/s11671-024-04055-z","DOIUrl":"10.1186/s11671-024-04055-z","url":null,"abstract":"<p><p>Candida albicans is one of the most dangerous pathogenic fungi in the world, according to the classification of the World Health Organization, due to the continued development of its resistance to currently available anticandidal agents. To overcome this problem, the current work provided a simple, one-step, cost-effective, and safe technique for the biosynthesis of new functionalized anticandidal selenium nanoparticles (Se NPs) against C. albicans ATCC10231 using the cell-free supernatant of Limosilactobacillus fermentum (OR553490) strain. The bacterial strain was isolated from yogurt samples available in supermarkets, in Damietta, Egypt. The mixing ratio of 1:9 v/v% between cell-free bacterial metabolites and sodium selenite (5 mM) for 72 h at 37 °C were the optimum conditions for Se NPs biosynthesis. Ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), X-ray diffraction (XRD), Zeta analyses, and elemental analysis system (EDS) were used to evaluate the optimized Se NPs. The Se NPs absorption peak appeared at 254 nm. Physicochemical analysis of Se NPs revealed the crystalline-shaped and well-dispersed formation of NPs with an average particle size of 17-30 nm. Se NPs have - 11.8 mV, as seen by the zeta potential graph. FT-IR spectrum displayed bands of symmetric and asymmetric amines at 3279.36 cm^-1 and 2928.38 cm^-1, aromatic and aliphatic (C-N) at 1393.32 cm^-1 and 1237.11.37 cm^-1 confirming the presence of proteins as stabilizing and capping agents. Se NPs acted as a superior inhibitor of C. albicans with an inhibition zone of 26 ± 0.03 mm and MIC value of 15 µg/mL compared to one of the traditional anticandidal agent, miconazole, which revealed 18 ± 0.14 mm and 75 µg/mL. The cytotoxicity test shows that Se NPs have a low toxic effect on the normal keratinocyte (IC₅₀ ≈ 41.5 μg/mL). The results indicate that this green synthesis of Se NPs may have a promising potential to provide a new strategy for drug therapy.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"115"},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-scale structural characterization of ceramic-based photonic glasses for structural colors.","authors":"Yen Häntsch, Ana Diaz, Mirko Holler, Tobias Krekeler, Martin Ritter, Sabine Rosenfeldt, Markus Retsch, Kaline P Furlan","doi":"10.1186/s11671-024-04057-x","DOIUrl":"10.1186/s11671-024-04057-x","url":null,"abstract":"<p><p>Structural colors arise from selective light interaction with (nano)structures, which give them advantages over pigmented colors such as resistance to fading and possibility to be fabricated out of traditional low-cost and non-toxic materials. Since the color arises from the photonic (nano)structures, different structural features can impact their photonic response and thus, their color. Therefore, the detailed characterization of their structural features is crucial for further improvement of structural colors. In this work, we present a detailed multi-scale structural characterization of ceramic-based photonic glasses by using a combination of high-resolution ptychographic X-ray computed tomography and small angle X-ray scattering. Our results uncover the structure-processing-properties' relationships of such nanoparticles-based photonic glasses and point out to the need of a review of the structural features used in simulation models concomitantly with the need for further investigations by experimentalists, where we point out exactly which structural features need to be improved.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"114"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11231108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement noise margin and delay time performance of novel punch-through nMOS for single-carrier CMOS.","authors":"Jyi-Tsong Lin, Pei-Zhang Xie, Wei-Han Lee","doi":"10.1186/s11671-024-04064-y","DOIUrl":"10.1186/s11671-024-04064-y","url":null,"abstract":"<p><p>In this paper, we propose the use of punch-through nMOS (PTnMOS) as an alternative to pMOS in complementary metal oxide semiconductor (CMOS) circuits. According to the TCAD simulation results, PTnMOS exhibit sub-threshold characteristics similar to those of pMOS and can be formed by simply changing the doping concentration of the source and drain. Without the need for sizing, which solves the area occupation problem caused by the need to increase the width of pMOS due to insufficient hole mobility. In addition, we compose a PTnMOS and nMOS without sizing to form a single-carrier CMOS in which only electrons are transmitted, and We extract its performance for comparison with conventional CMOS (W_p/W_n = 1). The results indicate that single-carrier CMOS has symmetric noise margin and 29% faster delay time compared to conventional CMOS (W_p/W_n = 1). If III-V or II-VI group materials could be applied to single-carrier CMOS, not only could costs be reduced and wafer area occupancy minimized, but also significant improvements in the performance and bandwidth application of microwave circuits could be achieved.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"113"},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review of plastic waste nanocomposites: assessment of features and applications.","authors":"Ida Rasilainen, Ville Lahtela, Timo Kärki","doi":"10.1186/s11671-024-04062-0","DOIUrl":"10.1186/s11671-024-04062-0","url":null,"abstract":"<p><p>Hundreds of millions of metric tons of plastic waste are generated globally every year. Processing waste into secondary raw material is preferred over energy production and landfilling. However, mechanical recycling generally deteriorates the properties of plastic waste limiting its range of potential applications. Nanocomposite fabrication is a solution to recycle plastic waste into value-added applications due to improved properties generated by nanomaterial reinforcement, however received little study. The aim of this review is to present the current status, identify research gaps and provide topics for further research of polymer nanocomposites prepared from plastic waste in respect to utilized materials, processing methods, enhanced properties, sustainability, economics, nanomaterial safety, and applications. It is found that morphological, mechanical, thermal, flame retardancy, physical, barrier, electrical and shielding properties of plastic waste can be enhanced with low loadings of different nanomaterials making them promising materials for various applications including electronic, shielding, thermal, packaging, filtration, and water treatment. Utilization of plastic waste instead of virgin polymers can be beneficial in respect to economics and sustainability, but the energy intensive and expensive production of the most nanomaterials, and the plastic waste pretreatment methods can negate these benefits. To enhance sustainability, further research should be conducted on utilization of energy friendly nanomaterials in plastic waste nanocomposites. Further research is needed also on polymer nanocomposite safety because of the unknow composition of the plastic waste and the potential for nanomaterial release during nanocomposite's life cycle. All in all, further research and national regulations and guidance are needed on virgin polymer and plastic waste nanocomposites.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"112"},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual polarity open circuit voltage in triboelectric nanogenerators originated from two states series impedance.","authors":"Jiwon Jeong, Jiyoung Ko, Jongjin Lee","doi":"10.1186/s11671-024-04056-y","DOIUrl":"10.1186/s11671-024-04056-y","url":null,"abstract":"<p><p>Experimental and simulation studies demonstrated that the initial voltage setting significantly influences the open-circuit voltage (V_OC) in triboelectric nanogenerators (TENGs). Utilizing diode configurations, we consistently observed two distinct V_OCs independent of the initial settings. A lower V_OC corresponded to the surface voltage (V_Surface), while a higher V_OC was amplified by the product of the V_Surface and the TENG's characteristic impedance ratio. Notably, a lower measurement system capacitance provided a more precise representation of the inherent characteristics of the TENG. Conversely, an increase in system impedance led to a convergence of the two V_OCs and a reduction in their magnitudes relative to V_Surface. These findings suggest that optimizing the initial/repeated charge balancing and minimizing capacitive loads are crucial for maximizing TENG output power in practical applications.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"111"},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graphene-based nanotechnology in the Internet of Things: a mini review.","authors":"Sharmi Ganguly, Joydip Sengupta","doi":"10.1186/s11671-024-04054-0","DOIUrl":"10.1186/s11671-024-04054-0","url":null,"abstract":"<p><p>Graphene, a 2D nanomaterial, has garnered significant attention in recent years due to its exceptional properties, offering immense potential for revolutionizing various technological applications. In the context of the Internet of Things (IoT), which demands seamless connectivity and efficient data processing, graphene's unique attributes have positioned it as a promising candidate to prevail over challenges and optimize IoT systems. This review paper aims to provide a brief sketch of the diverse applications of graphene in IoT, highlighting its contributions to sensors, communication systems, and energy storage devices. Additionally, it discusses potential challenges and prospects for the integration of graphene in the rapidly evolving IoT landscape.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"110"},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11219675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141494457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}