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Recent advances in two-dimensional perovskite materials for light-emitting diodes. 用于发光二极管的二维过氧化物材料的最新进展。
Discover nano Pub Date : 2024-07-02 DOI: 10.1186/s11671-024-04044-2
Deepika Tyagi, Vijay Laxmi, Nilanjan Basu, Leelakrishna Reddy, Yibin Tian, Zhengbiao Ouyang, Pramoda K Nayak
{"title":"Recent advances in two-dimensional perovskite materials for light-emitting diodes.","authors":"Deepika Tyagi, Vijay Laxmi, Nilanjan Basu, Leelakrishna Reddy, Yibin Tian, Zhengbiao Ouyang, Pramoda K Nayak","doi":"10.1186/s11671-024-04044-2","DOIUrl":"10.1186/s11671-024-04044-2","url":null,"abstract":"<p><p>Light-emitting diodes (LEDs) are an indispensable part of our daily life. After being studied for a few decades, this field still has some room for improvement. In this regard, perovskite materials may take the leading role. In recent years, LEDs have become a most explored topic, owing to their various applications in photodetectors, solar cells, lasers, and so on. Noticeably, they exhibit significant characteristics in developing LEDs. The luminous efficiency of LEDs can be significantly enhanced by the combination of a poor illumination LED with low-dimensional perovskite. In 2014, the first perovskite-based LED was illuminated at room temperature. Furthermore, two-dimensional (2D) perovskites have enriched this field because of their optical and electronic properties and comparatively high stability in ambient conditions. Recent and relevant advancements in LEDs using low-dimensional perovskites including zero-dimensional to three-dimensional materials is reported. The major focus of this article is based on the 2D perovskites and their heterostructures (i.e., a combination of 2D perovskites with transition metal dichalcogenides, graphene, and hexagonal boron nitride). In comparison to 2D perovskites, heterostructures exhibit more potential for application in LEDs. State-of-the-art perovskite-based LEDs, current challenges, and prospects are also discussed.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"109"},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11219672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141494459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanosheet integration of induced tunnel field-effect transistor with lower cost and lower power. 低成本、低功耗的诱导隧道场效应晶体管纳米片集成。
Discover nano Pub Date : 2024-07-02 DOI: 10.1186/s11671-024-04036-2
Jyi-Tsong Lin, Chia-Yo Kuo
{"title":"Nanosheet integration of induced tunnel field-effect transistor with lower cost and lower power.","authors":"Jyi-Tsong Lin, Chia-Yo Kuo","doi":"10.1186/s11671-024-04036-2","DOIUrl":"10.1186/s11671-024-04036-2","url":null,"abstract":"<p><p>Nanosheet transistors are poised to become the preferred choice for the next generation of smaller-sized devices in the future. To address the future demand for high-performance and low-power computing applications, this study proposes a nanosheet structure with a vertically stacked design, featuring a high I<sub>ON</sub>/I<sub>OFF</sub> ratio. This Nanosheet design is combined with an induced tunnel field-effect transistor. By utilizing SiGe with a carrier mobility three times that of Si and employing a line tunneling mechanism, the research successfully achieves superior Band to Band characteristics, resulting in improved switching behavior and a lower Subthreshold Swing (SS). Comparative studies were conducted on three TFET types: Nanosheet PIN TFET, Nanosheet Schottky iTFET, and Fin iTFET. Results show that the Nanosheet PIN TFET has a higher I<sub>ON</sub>/I<sub>OFF</sub> ratio but poorer SSavg values at 47.63 mV/dec compared to the others. However, with a SiGe Body thickness of 3 nm, both Nanosheet iTFET and Fin iTFET exhibit higher I<sub>ON</sub>/I<sub>OFF</sub> ratios and superior SSavg values at 17.64 mV/dec. These findings suggest the potential of Nanosheet iTFET and Fin iTFET for low-power, lower thermal budgets, and fast-switching applications.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"108"},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11219690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141494458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low ppm NO2 detection through advanced ultrasensitive copper oxide gas sensor. 通过先进的超灵敏氧化铜气体传感器检测低ppm二氧化氮。
Discover nano Pub Date : 2024-06-24 DOI: 10.1186/s11671-024-04039-z
Smriti Sihag, Rita Dahiya, Suman Rani, Priyanka Berwal, Anushree Jatrana, Avnish Kumar Sisodiya, Ashutosh Sharma, Vinay Kumar
{"title":"Low ppm NO<sub>2</sub> detection through advanced ultrasensitive copper oxide gas sensor.","authors":"Smriti Sihag, Rita Dahiya, Suman Rani, Priyanka Berwal, Anushree Jatrana, Avnish Kumar Sisodiya, Ashutosh Sharma, Vinay Kumar","doi":"10.1186/s11671-024-04039-z","DOIUrl":"10.1186/s11671-024-04039-z","url":null,"abstract":"<p><p>The imperative development of a cutting-edge environmental gas sensor is essential to proficiently monitor and detect hazardous gases, ensuring comprehensive safety and awareness. Nanostructures developed from metal oxides are emerging as promising candidates for achieving superior performance in gas sensors. NO<sub>2</sub> is one of the toxic gases that affects people as well as the environment so its detection is crucial. The present study investigates the gas sensing capability of copper oxide-based sensor for 5 ppm of NO<sub>2</sub> gas at 100 °C. The sensing material was synthesized using a facile precipitation method and characterized by XRD, FE-SEM, UV-visible spectroscopy, photoluminescence spectroscopy, XPS and BET techniques. The developed material shows a response equal to 67.1% at optimal temperature towards 5 ppm NO<sub>2</sub> gas. The sensor demonstrated an impressive detection limit of 300 ppb, along with a commendable percentage response of 5.2%. Under optimized conditions, the synthesized material demonstrated its high selectivity, as evidenced by the highest percentage response recorded for NO<sub>2</sub> gas among NO<sub>2</sub>, NH<sub>3</sub>, CO, CO<sub>2</sub> and H<sub>2</sub>S.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"107"},"PeriodicalIF":0.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141443863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of mechanical cues on key cell functions and cell-nanoparticle interactions. 机械线索对关键细胞功能和细胞-纳米粒子相互作用的影响
Discover nano Pub Date : 2024-06-22 DOI: 10.1186/s11671-024-04052-2
Petra Elblová, Mariia Lunova, Alexandr Dejneka, Milan Jirsa, Oleg Lunov
{"title":"Impact of mechanical cues on key cell functions and cell-nanoparticle interactions.","authors":"Petra Elblová, Mariia Lunova, Alexandr Dejneka, Milan Jirsa, Oleg Lunov","doi":"10.1186/s11671-024-04052-2","DOIUrl":"10.1186/s11671-024-04052-2","url":null,"abstract":"<p><p>In recent years, it has been recognized that mechanical forces play an important regulative role in living organisms and possess a direct impact on crucial cell functions, ranging from cell growth to maintenance of tissue homeostasis. Advancements in mechanobiology have revealed the profound impact of mechanical signals on diverse cellular responses that are cell type specific. Notably, numerous studies have elucidated the pivotal role of different mechanical cues as regulatory factors influencing various cellular processes, including cell spreading, locomotion, differentiation, and proliferation. Given these insights, it is unsurprising that the responses of cells regulated by physical forces are intricately linked to the modulation of nanoparticle uptake kinetics and processing. This complex interplay underscores the significance of understanding the mechanical microenvironment in shaping cellular behaviors and, consequently, influencing how cells interact with and process nanoparticles. Nevertheless, our knowledge on how localized physical forces affect the internalization and processing of nanoparticles by cells remains rather limited. A significant gap exists in the literature concerning a systematic analysis of how mechanical cues might bias the interactions between nanoparticles and cells. Hence, our aim in this review is to provide a comprehensive and critical analysis of the existing knowledge regarding the influence of mechanical cues on the complicated dynamics of cell-nanoparticle interactions. By addressing this gap, we would like to contribute to a detailed understanding of the role that mechanical forces play in shaping the complex interplay between cells and nanoparticles.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"106"},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11193707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zinc oxide and copper oxide nanoparticles as a potential solution for controlling Phytophthora infestans, the late blight disease of potatoes. 氧化锌和氧化铜纳米粒子作为控制马铃薯晚疫病 Phytophthora infestans 的潜在解决方案。
Discover nano Pub Date : 2024-06-22 DOI: 10.1186/s11671-024-04040-6
Amira A AlHarethi, Qais Y Abdullah, Hala J AlJobory, AbdulRahman M Anam, Ramadan A Arafa, Khaled Y Farroh
{"title":"Zinc oxide and copper oxide nanoparticles as a potential solution for controlling Phytophthora infestans, the late blight disease of potatoes.","authors":"Amira A AlHarethi, Qais Y Abdullah, Hala J AlJobory, AbdulRahman M Anam, Ramadan A Arafa, Khaled Y Farroh","doi":"10.1186/s11671-024-04040-6","DOIUrl":"10.1186/s11671-024-04040-6","url":null,"abstract":"<p><p>Late blight, caused by Phytophthora infestans, is a major potato disease globally, leading to significant economic losses of $6.7 billion. To address this issue, we evaluated the antifungal activity of ZnO and CuO nanoparticles (NPs) against P. infestans for the first time in laboratory and greenhouse conditions. Nanoparticles were synthesized via a chemical precipitation method and characterized using various techniques. The XRD results revealed that the synthesized ZnO nanoparticles had a pure hexagonal wurtzite crystalline structure, whereas the CuO NPs had a monoclinic crystalline structure. TEM images confirmed the synthesis of quasi-spherical nanoparticles with an average size of 11.5 nm for ZnO NPs and 24.5 nm for CuO NPs. The UV-Vis Spectral Report showed peaks corresponding to ZnO NPs at 364 nm and 252 nm for CuO NPs.In an in vitro study, both ZnO and CuO NPs significantly (p < 0.05) inhibited the radial growth of P. infestans at all tested concentrations compared to the untreated control. The highest inhibitory effect of 100% was observed with ZnO and CuO NPs at 30 mg/L. A lower inhibition of 60.4% was observed with 10 mg/L CuO NPs. Under greenhouse conditions, 100 mg/L ZnO NPs was the most effective treatment for controlling potato late blight, with an efficacy of 71%. CuO NPs at 100 mg/L followed closely, with an efficacy of 69%. Based on these results, ZnO and CuO NPs are recommended as promising eco-friendly fungicides for the management and control of potato late blight after further research.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"105"},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11193706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomedical applications of graphene-based nanomaterials: recent progress, challenges, and prospects in highly sensitive biosensors. 石墨烯基纳米材料的生物医学应用:高灵敏度生物传感器的最新进展、挑战和前景。
Discover nano Pub Date : 2024-06-17 DOI: 10.1186/s11671-024-04032-6
Arabinda Baruah, Rachita Newar, Saikat Das, Nitul Kalita, Masood Nath, Priya Ghosh, Sampath Chinnam, Hemen Sarma, Mahesh Narayan
{"title":"Biomedical applications of graphene-based nanomaterials: recent progress, challenges, and prospects in highly sensitive biosensors.","authors":"Arabinda Baruah, Rachita Newar, Saikat Das, Nitul Kalita, Masood Nath, Priya Ghosh, Sampath Chinnam, Hemen Sarma, Mahesh Narayan","doi":"10.1186/s11671-024-04032-6","DOIUrl":"10.1186/s11671-024-04032-6","url":null,"abstract":"<p><p>Graphene-based nanomaterials (graphene, graphene oxide, reduced graphene oxide, graphene quantum dots, graphene-based nanocomposites, etc.) are emerging as an extremely important class of nanomaterials primarily because of their unique and advantageous physical, chemical, biological, and optoelectronic aspects. These features have resulted in uses across diverse areas of scientific research. Among all other applications, they are found to be particularly useful in designing highly sensitive biosensors. Numerous studies have established their efficacy in sensing pathogens and other biomolecules allowing for the rapid diagnosis of various diseases. Considering the growing importance and popularity of graphene-based materials for biosensing applications, this review aims to provide the readers with a summary of the recent progress in the concerned domain and highlights the challenges associated with the synthesis and application of these multifunctional materials.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"103"},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11183028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141332635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the efficacy of subwavelength gratings as short-wavelength infrared filters. 探索亚波长光栅作为短波长红外滤光片的功效。
Discover nano Pub Date : 2024-06-17 DOI: 10.1186/s11671-024-04045-1
Hezhuang Liu, Yixuan Huang, Jiang Wu
{"title":"Exploring the efficacy of subwavelength gratings as short-wavelength infrared filters.","authors":"Hezhuang Liu, Yixuan Huang, Jiang Wu","doi":"10.1186/s11671-024-04045-1","DOIUrl":"10.1186/s11671-024-04045-1","url":null,"abstract":"<p><p>Advancements in nanofabrication technology have greatly facilitated research on nanostructures and their associated properties. Among these structures, subwavelength components have emerged as promising candidates for ultra-compact optical elements, can potentially supplant conventional optical components and enable the realization of compact and efficient optical devices. Spectral analysis within the infrared spectrum offers a wealth of information for monitoring crop health, industrial processes, and target identification. However, conventional spectrometers are typically bulky and expensive, driving an increasing demand for cost-effective spectral sensors. Here we investigate three distinct subwavelength grating structures designed to function as narrowband filters within the short-wavelength infrared (SWIR) range. Through simple adjustments to the period of grating strips, these filters selectively transmit light across a wide wavelength range from 1100 to 1700 nm with transmission exceeding 70% and full width at half maximum (FWHM) down to 6 nm. Based on a simple design, the results present great potential of subwavelength grating filters for multiband integration and developing ultra-compact spectral sensors.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"104"},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11183007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141422045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on different isolation technology on the performance of blue micro-LEDs array applications. 研究不同隔离技术对蓝色微型 LED 阵列应用性能的影响。
Discover nano Pub Date : 2024-06-13 DOI: 10.1186/s11671-024-04047-z
Shao-Hua Lin, Yu-Yun Lo, Yu-Hsuan Hsu, Chien-Chung Lin, Hsiao-Wen Zan, Yi-Hsin Lin, Dong-Sing Wuu, Ching-Lien Hsiao, Ray-Hua Horng
{"title":"Study on different isolation technology on the performance of blue micro-LEDs array applications.","authors":"Shao-Hua Lin, Yu-Yun Lo, Yu-Hsuan Hsu, Chien-Chung Lin, Hsiao-Wen Zan, Yi-Hsin Lin, Dong-Sing Wuu, Ching-Lien Hsiao, Ray-Hua Horng","doi":"10.1186/s11671-024-04047-z","DOIUrl":"10.1186/s11671-024-04047-z","url":null,"abstract":"<p><p>In this study, a 3 × 3 blue micro-LED array with a pixel size of 10 × 10 μm<sup>2</sup> and a pitch of 15 μm was fabricated on an epilayer grown on a sapphire substrate using metalorganic chemical vapor deposition technology. The fabrication process involved photolithography, wet and dry etching, E-beam evaporation, and ion implantation technology. Arsenic multi-energy implantation was utilized to replace the mesa etching for electrical isolation, where the implantation depth increased with the average energy. Different ion depth profiles had varying effects on electrical properties, such as forward current and leakage currents, potentially causing damage to the n-GaN layer and increasing the series resistance of the LEDs. As the implantation depth increased, the light output power and peak external quantum efficiency of the LEDs also increased, improving from 5.33 to 9.82%. However, the efficiency droop also increased from 46.3 to 48.6%.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"102"},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11176112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remarkably high tensile strength and lattice thermal conductivity in wide band gap oxidized holey graphene C2O nanosheet. 宽带隙氧化空洞石墨烯 C2O 纳米片具有极高的拉伸强度和晶格导热性。
Discover nano Pub Date : 2024-06-11 DOI: 10.1186/s11671-024-04046-0
Fazel Shojaei, Qinghua Zhang, Xiaoying Zhuang, Bohayra Mortazavi
{"title":"Remarkably high tensile strength and lattice thermal conductivity in wide band gap oxidized holey graphene C<sub>2</sub>O nanosheet.","authors":"Fazel Shojaei, Qinghua Zhang, Xiaoying Zhuang, Bohayra Mortazavi","doi":"10.1186/s11671-024-04046-0","DOIUrl":"10.1186/s11671-024-04046-0","url":null,"abstract":"<p><p>Recently, the synthesis of oxidized holey graphene with the chemical formula C<sub>2</sub>O has been reported (J. Am. Chem. Soc. 2024, 146, 4532). We herein employed a combination of density functional theory (DFT) and machine learning interatomic potential (MLIP) calculations to investigate the electronic, optical, mechanical and thermal properties of the C<sub>2</sub>O monolayer, and compared our findings with those of its C<sub>2</sub>N counterpart. Our analysis shows that while the C<sub>2</sub>N monolayer exhibits delocalized π-conjugation and shows a 2.47 eV direct-gap semiconducting behavior, the C<sub>2</sub>O counterpart exhibits an indirect gap of 3.47 eV. We found that while the C<sub>2</sub>N monolayer exhibits strong absorption in the visible spectrum, the initial absorption peaks in the C<sub>2</sub>O lattice occur at around 5 eV, falling within the UV spectrum. Notably, we found that the C<sub>2</sub>O nanosheet presents significantly higher tensile strength compared to its C<sub>2</sub>N counterpart. MLIP-based calculations show that at room temperature, the C<sub>2</sub>O nanosheet can exhibit remarkably high tensile strength and lattice thermal conductivity of 42 GPa and 129 W/mK, respectively. The combined insights from DFT and MLIP-based results provide a comprehensive understanding of the electronic and optical properties of C<sub>2</sub>O nanosheets, suggesting them as mechanically robust and highly thermally conductive wide bandgap semiconductors.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"99"},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of super nanoantimicrobials combining AgCl, tetracycline and benzalkonium chloride. 结合氯化银、四环素和苯扎氯铵开发超级纳米抗菌剂。
Discover nano Pub Date : 2024-06-11 DOI: 10.1186/s11671-024-04043-3
Syed Imdadul Hossain, Diellza Bajrami, Nazan Altun, Margherita Izzi, Cosima Damiana Calvano, Maria Chiara Sportelli, Luigi Gentile, Rosaria Anna Picca, Pelayo Gonzalez, Boris Mizaikoff, Nicola Cioffi
{"title":"Development of super nanoantimicrobials combining AgCl, tetracycline and benzalkonium chloride.","authors":"Syed Imdadul Hossain, Diellza Bajrami, Nazan Altun, Margherita Izzi, Cosima Damiana Calvano, Maria Chiara Sportelli, Luigi Gentile, Rosaria Anna Picca, Pelayo Gonzalez, Boris Mizaikoff, Nicola Cioffi","doi":"10.1186/s11671-024-04043-3","DOIUrl":"10.1186/s11671-024-04043-3","url":null,"abstract":"<p><p>In this work, we demonstrate that a simple argentometric titration is a scalable, fast, green and robust approach for producing AgCl/antibiotic hybrid antimicrobial materials. We titrated AgNO<sub>3</sub> into tetracycline hydrochloride (TCH) aqueous solution, thus forming AgCl/TCH in a one-step procedure. Furthermore, we investigated the one-pot synthesis of triply synergistic super-nanoantimicrobials, combining an inorganic source of Ag<sup>+</sup> ions (AgCl), a disinfecting agent (benzyl-dimethyl-hexadecyl-ammonium chloride, BAC) and a molecular antibiotic (tetracycline hydrochloride, TCH). Conventional antimicrobial tests, industrial biofilm detection protocols, and in situ IR-ATR microbial biofilm monitoring, have been adapted to understand the performance of the synthesized super-nanoantimicrobial. The resulting hybrid AgCl/BAC/TCH nanoantimicrobials are found to be synergistically active in eradicating Salmonella enterica and Lentilactobacillus parabuchneri bacteria and biofilms. This study paves the way for the development of a new class of super-efficient nanoantimicrobials that combine relatively low amounts of multiple active species into a single (nano)formulation, thus preventing the development of antimicrobial resistance towards a single active principle.</p>","PeriodicalId":72828,"journal":{"name":"Discover nano","volume":"19 1","pages":"100"},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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