Diabetes epidemiology and management最新文献

{"title":"Diabetes in pregnancy: Anxious minds precarious times","authors":"Ahmed Hasan,&nbsp;Almas Zafar","doi":"10.1016/j.deman.2024.100235","DOIUrl":"10.1016/j.deman.2024.100235","url":null,"abstract":"<div><p>Gestational diabetes is a prevalent condition that affects up to 24.2 % of women in South-East Asia. A study conducted in Iran highlighted the correlation between gestational diabetes and anxiety/depression. Improvements can be made by conducting a cohort study to better establish the causality between the compounding factors of mental health and gestational diabetes. Additionally, conducting a follow-up study in a region with a higher incidence of gestational diabetes, such as South-East Asia, can broaden the geographic distribution of the available data. We must promote awareness campaigns highlighting this correlation to improve holistic healthcare strategies.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"16 ","pages":"Article 100235"},"PeriodicalIF":1.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970624000398/pdfft?md5=fec62aa64c34fd7b15ca81914bd6bdbf&pid=1-s2.0-S2666970624000398-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a Support Tool for Diabetes Control in primary care – A Qualitative study with primary care staff","authors":"Ricko Damberg Nissen,&nbsp;Jesper Bo Nielsen","doi":"10.1016/j.deman.2024.100228","DOIUrl":"https://doi.org/10.1016/j.deman.2024.100228","url":null,"abstract":"<div><h3>Background</h3><p>In Denmark, the primary responsibility for treatment of patients with diabetes has shifted from hospitals to primary care. Thus, general practice has assumed responsibility for a complex and multifaceted disease. To address this situation a stratification tool to assist the nurses in primary care in their work with diabetes patients was developed.</p></div><div><h3>Aim</h3><p>In the present study we evaluated this stratification tool.</p></div><div><h3>Method</h3><p>The evaluation was based on 18 semi-structured interviews conducted with nurses employed in primary care across Denmark, and who had experience with the stratification tool. The data was subsequently analyzed by content and thematic analyses.</p></div><div><h3>Results</h3><p>The interviewees were generally positive towards the stratification tool. The analyses established three themes 1. Treatment, 2. Resources, and 3. Points of critique.</p></div><div><h3>Conclusions</h3><p>Our study indicates that a combined tool for risk stratification of patients with T2D and for subsequent risk communication is perceived as positive and supportive for quality in care. It is seen to potentially reduce the resources presently allocated to well-regulated and stable T2D patients. These resources will eventually be available for other patients. The positive reception by nurses supports that tools like the Diabetes Control Support Tool could be developed and implemented in general practice.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"16 ","pages":"Article 100228"},"PeriodicalIF":1.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970624000337/pdfft?md5=9c4c5a22cb9a7b99acc7e735767daafd&pid=1-s2.0-S2666970624000337-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141540064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of non-fasting patients with diabetes type 2 in the DAR global surveys of 2020 and 2022","authors":"Bachar Afandi ,&nbsp;Khadija Hafidh ,&nbsp;Rachid Malek ,&nbsp;M Yakoob Ahmedani ,&nbsp;Inass Shaltout ,&nbsp;Reem Alamoudi ,&nbsp;Zanariah Hussein ,&nbsp;Mohamed Hassanein","doi":"10.1016/j.deman.2024.100217","DOIUrl":"https://doi.org/10.1016/j.deman.2024.100217","url":null,"abstract":"<div><h3>Introduction</h3><p>The decision to fast or not is quite complex. Personal, medical and religious matters may influence it for individuals with diabetes. However, a diagnosis of diabetes does not constitute an automatic exemption from Ramadan fasting. We aimed to evaluate the characteristics of the non-fasting cohort and explore the potential reasons during Ramadan through the global Ramadan surveys of 2020 and 2022.</p></div><div><h3>Method</h3><p>The Diabetes and Ramadan (DaR) Global Study is an observational retrospective survey conducted between 2020 and 2022, which included adult patients (18 and older) who fasted and those who opted not to fast. The survey captured demographic data and patient characteristics (co-morbidities, duration and type of diabetes, diabetes-related complications and medications, development of acute complications during Ramadan, hospitalisations and ER visits) for both groups.</p></div><div><h3>Results</h3><p>Of 12,059 patients, 1822 (14.5 %) did not fast during Ramadan; that population leaned towards females (54.6 %). They had an average age of 60.58 years (SD=12.12) with a statistically significant difference from the fasting population, averaging 54.29±11.45 (<em>p</em> = 0.000). Also of note was the more significant average duration of diabetes in the non-fasting cohort (12.54 years vs 9.44). There are notable regional differences in rates of fasting that ranged between 6.3 % and up to 51.2 % of patients opting not fast in certain regions (Chart 1). The risk factors that showed apparent differences of high statistical significance (<em>p</em> ≤ 0.001) included: long duration of diabetes of over ten years, age above 60+ years, HbA1c value over 9 %, use of insulin therapy, and being affected by one or more vascular complications (these include CKD, CVD, and diabetic foot problems).</p></div><div><h3>Conclusions</h3><p>Many factors and comorbidities might influence patients’ decisions when planning Ramadan fasting. The non-fasting population's demographic and clinical profiles reveal distinctive features, emphasising a need for tailored risk assessments. Furthermore, regional disparities in the decision to fast underscore the multifaceted nature of this decision-making process. The new IDF-DAR risk assessment tool can help to stratify patients’ risk during Ramadan fasting and bridge the gap among different populations and cultures.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"15 ","pages":"Article 100217"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970624000222/pdfft?md5=4eb5e3f489f47bab3d4af0c5dbecd660&pid=1-s2.0-S2666970624000222-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140558176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospital prevalence of diabetes mellitus among under 15 children in Butembo: A retrospective study at the University Clinics of Graben","authors":"Roland Muyisa ,&nbsp;Emile Watumwa ,&nbsp;Apollinaire SaaSita ,&nbsp;Judith Kithonga ,&nbsp;Judith Malembe ,&nbsp;Wivine Kitasuvirwa ,&nbsp;Ghyslaine Kalivanda ,&nbsp;Mupenzi Mumbere ,&nbsp;Francois Mbahweka ,&nbsp;Soly Kamwira","doi":"10.1016/j.deman.2024.100218","DOIUrl":"https://doi.org/10.1016/j.deman.2024.100218","url":null,"abstract":"<div><h3>Introduction</h3><p>Mellitus diabetes is an endocrine trouble characterized by chronic high glycemia caused by a relative or absolute insulin deficiency. It is a public health problem because of its frequency associated with high morbi-mortality. The objective of this research was to determine the frequency of mellitus diabetes in under 15-year-old patients in Butembo Town.</p></div><div><h3>Method</h3><p>it was a cross-sectional descriptive study realized at the University Clinics of Graben from January 1st, 2017 to December 31st, 2021.</p></div><div><h3>Results</h3><p>Between 2017 and 2021, 3,681 children and adolescents were hospitalized at the University Clinics of the Graben Pediatrics Department. Out of them, 49 were diagnosed with mellitus diabetes, which indicates a prevalence of 1.331 %. The majority of patients were males, with high frequencies observed between the ages of 2 to 12 years. Common complaints included coma, polyurea-polydipsia, vision troubles, fever, weight loss, and growth retardation. Complications in infants and adolescents with diabetes included retinopathies, neuropathies, coma, infection, and ketoacidosis. The patients were admitted with extreme glycemia, with many suffering from hypoglycemia. Forty-three out of the 49 patients received insulin, and five of them died.</p></div><div><h3>Conclusion</h3><p>Mellitus diabetes in young remains a health problem in Butembo. Effective healthcare must include medical professionals, the population, and the state.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"15 ","pages":"Article 100218"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970624000234/pdfft?md5=3983443ffc27baa3220ce1f0574b1df0&pid=1-s2.0-S2666970624000234-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140649591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The correlation of ABC goal attainment with insulin resistance/sensitivity in Syrian type 2 diabetes patients","authors":"Samer Younes","doi":"10.1016/j.deman.2024.100221","DOIUrl":"10.1016/j.deman.2024.100221","url":null,"abstract":"<div><h3>Background</h3><p>The rising prevalence of type 2 diabetes (T2D) in Syria emphasizes the urgent requirement for effective management approaches. The ABC goals, which include maintaining glycated hemoglobin levels below 7 %, blood pressure below 140/90 mmHg, and low-density lipoprotein cholesterol levels below 100 mg/dl, serve as crucial benchmarks for managing T2D and its associated comorbidities.</p></div><div><h3>Methods</h3><p>In this cross-sectional study, the achievement of ABC goals was retrospectively examined among 681 clinically diagnosed T2D patients (not on Insulin) who participated in a six-year online lifestyle intervention program for diabetes management at the Freedom from Diabetes Clinic in Syria between January 2016 and December 2022.</p></div><div><h3>Results</h3><p>Out of the participants, 152 (22.3 %) successfully achieved all three ABC goals, while 306 (45.0 %) and 183 (26.9 %) achieved two or one goal(s) respectively. The factors influencing the attainment of all three ABC goals revealed a significant association with older age (&gt;50 years), lower body mass index (&lt;25 kg/m2), and lower insulin resistance (Homeostatic Model Assessment of Insulin Resistance &lt; 2.5). Furthermore, patients who successfully achieved all three ABC goals exhibited lower insulin resistance, improved lipid profiles, and higher insulin sensitivity and beta cell function.</p></div><div><h3>Conclusion</h3><p>This study offers new insights into the relationship between insulin resistance/sensitivity and the achievement of ABC goals in the Syrian population with T2D, underscoring the necessity for tailored strategies to enhance comprehensive diabetes management.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"15 ","pages":"Article 100221"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266697062400026X/pdfft?md5=f5fd82ac6f31fec02870d126545664a8&pid=1-s2.0-S266697062400026X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141025367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of prediabetes with stroke in young metabolically healthy tobacco users: A population-based analysis","authors":"Advait Vasavada ,&nbsp;Arankesh Mahadevan ,&nbsp;Manisha Jain ,&nbsp;Subramanian Gnanaguruparan ,&nbsp;Rupak Desai","doi":"10.1016/j.deman.2024.100210","DOIUrl":"https://doi.org/10.1016/j.deman.2024.100210","url":null,"abstract":"<div><h3>Background</h3><p>Diabetes and tobacco use are well-established risk factors for stroke. However, the intersection of prediabetes, tobacco use, and stroke among young individuals remains underexplored. This study aims to investigate the association between pre-diabetes and stroke risk in young tobacco users.</p></div><div><h3>Methods</h3><p>Using the National Inpatient Sample (2019) and relevant ICD-10 codes, we identified young patients with tobacco use disorder and pre-diabetes. Regression analysis considered risk factors (gender, demographics, income, comorbidities) to assess stroke odds.</p></div><div><h3>Results</h3><p>Among 1,017,540 stroke hospitalizations, 1.9 % were pre-diabetic. Pre-diabetics were often older (median age 36 vs. 31), male (59.4 %), Black (33.8 %), and Hispanic (12.2 %), with higher rates of comorbidities, including drug abuse, alcohol abuse, COPD, and CKD (<em>p</em> &lt; 0.001). They also exhibited higher rates of stroke events (1.9 % vs. 0.5 %, <em>p</em> &lt; 0.001). Multivariable analysis after adjusting for confounders, young metabolically healthy smokers with pre-diabetes had a higher risk of stroke (aOR 3.31, 95 % CI [1.67–6.55], <em>p</em> &lt; 0.001).</p></div><div><h3>Conclusion</h3><p>Prediabetes could potentially triple stroke risk in young tobacco smokers. Prospective research is warranted to explore the causal association between pre-diabetes and stroke in the setting of tobacco use.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"15 ","pages":"Article 100210"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970624000155/pdfft?md5=a95efa544ec5b5f638e4cf57c191dc00&pid=1-s2.0-S2666970624000155-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140191303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early diagnosis of Charcot neuro-osteoarthropathy using MRI and its effect on patient outcomes: A seven-year retrospective audit","authors":"Laksh Lukkhoo ,&nbsp;Sharlene Vu ,&nbsp;Joanna Scheepers ,&nbsp;Deborah Schoen","doi":"10.1016/j.deman.2024.100208","DOIUrl":"https://doi.org/10.1016/j.deman.2024.100208","url":null,"abstract":"<div><h3>Background</h3><p>There remains a paucity of research comparing the diagnostic and therapeutic outcomes between Magnetic Resonance Imaging (MRI) and x-ray modalities for Charcot neuro-osteoarthropathy CNO. This retrospective study investigates the use of offloading devices, duration of offloading and final footwear outcomes dependent on imaging at diagnosis.</p></div><div><h3>Methods</h3><p>Medical records from a secondary hospital high-risk foot clinic in Perth, Western Australia, were systematically reviewed. Data collected included baseline medical history, location of CNO, Eichenholtz stage or Chantelau and Grutznel grade at diagnosis, type and duration of offloading, and final footwear outcomes.</p></div><div><h3>Results</h3><p>Twenty-eight patients met the inclusion criteria. All had diabetes and peripheral neuropathy. All patients received either an MRI (43%) or x-ray (57%) to confirm the diagnosis of active CNO. Five (17.9%) patients who were diagnosed on MRI had grade 0 CNO whilst 23 (82.1%) patients who were diagnosed on x-ray had stage 1 CNO. No statistical significance was found between the type and duration of offloading, resolution of CNO, footwear and transtibial amputation (TTA) outcomes across those diagnosed with MRI or x-ray.</p></div><div><h3>Conclusion</h3><p>No statistical significance in patient outcomes was found between those diagnosed with grade 0 on MRI and those diagnosed with stage 1 on x-ray.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"15 ","pages":"Article 100208"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970624000131/pdfft?md5=2b43b95910ef45809f0883f0f651baf3&pid=1-s2.0-S2666970624000131-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140180047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of isolated impaired fasting glucose among Asian Indians","authors":"Sathish Thirunavukkarasu","doi":"10.1016/j.deman.2024.100219","DOIUrl":"https://doi.org/10.1016/j.deman.2024.100219","url":null,"abstract":"","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"15 ","pages":"Article 100219"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970624000246/pdfft?md5=0b764abe89c0fb35014317b553ad8f8a&pid=1-s2.0-S2666970624000246-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140637941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase angle associated is with low ankle-brachial index in type 2 diabetes patients in Ghana","authors":"Jennifer Adjepong Agyekum ,&nbsp;Kwame Yeboah","doi":"10.1016/j.deman.2024.100216","DOIUrl":"https://doi.org/10.1016/j.deman.2024.100216","url":null,"abstract":"<div><h3>Background</h3><p>Type 2 diabetes (T2DM) is associated with high burden of atherosclerotic macrovascular disease which could be diagnosed with ankle-brachial index (ABI). Phase angle (PhA) from bioelectric impedance analysis is associated with the development of cardiovascular diseases. We investigated the association between low ABI and phase angle in T2DM patients in Ghana.</p></div><div><h3>Method</h3><p>In a cross-sectional study, 462 T2DM patients were systematically recruited for the study. ABI was measured using an 8 Hz continuous Doppler and ABI≤0.9 was considered to be low ABI. PhA was obtained from resistance and reactance from Bioelectric impedance analysis.</p></div><div><h3>Results</h3><p>The prevalence of low ABI was 16 % in the study population. T2DM patients with low ABI have decreased PhA (7.5 ± 1.9 vs 8.3 ± 2.2 units, <em>p</em> = 0.004) compared to those with normal ABI. An increase in phase angle by 1° was associated with a decrease in odds of having low ABI in unadjusted [OR (95 % CI) = 0.79 (0.48 – 0.95), <em>p</em> = 0.007] and adjusted models [0.88 (0.43 – 0.98), <em>p</em> = 0.036].</p></div><div><h3>Conclusion</h3><p>The prevalence of low ABI in T2DM patients in this study was 16 %. Also, PhA was lower in patients with low ABI compared to those with normal ABI.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"15 ","pages":"Article 100216"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970624000210/pdfft?md5=20ec669293ad684e8b07be6d669947a6&pid=1-s2.0-S2666970624000210-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140180046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving foot ulcer risk assessment and identifying associated factors: Results of an initiative enhancing diabetes care in primary settings","authors":"Ruben Silva-Tinoco ,&nbsp;Teresa Cuatecontzi-Xochitiotzi ,&nbsp;Yunuen Reyes-Paz ,&nbsp;Bianca Vidal-Santos ,&nbsp;Ana Galíndez-Fuentes ,&nbsp;Lilia Castillo-Martínez","doi":"10.1016/j.deman.2023.100195","DOIUrl":"10.1016/j.deman.2023.100195","url":null,"abstract":"<div><h3>Background</h3><p>Diabetes-related lower extremity complications contribute significantly to the overall disability burden of type 2 diabetes (T2D). The screening of Diabetic Foot Ulcer (DFU) risk is essential for the early identification of its components, thereby preventing the progression to advanced complications. Unfortunately, identifying elements associated with foot ulcer development is often poorly executed, especially in primary care settings, particularly in low-middle-income countries. We assess the prevalence of DFU risk and its components while exploring sociodemographic, clinical, and behavioral characteristics linked to DFU risk in patients with T2D.</p></div><div><h3>Methods</h3><p>This cross-sectional study examined the characteristics of the feet of subjects involved in an initiative to enhance the quality of diabetes care in primary healthcare settings. The assessment included the presence of foot deformities, peripheral neuropathy through Loss of Protective Sensation (LOPS) evaluation, peripheral arterial disease (PAD), and a history of foot ulcer or lower extremity amputations. Participants were classified according to the IWGDF Risk Classification and subsequently divided into two groups for analysis: those at high risk for DFU (Groups 1, 2, or 3) and those at low risk for DFU (Group 0). Logistic regression was employed to identify the factors associated with DFU risk and its components.</p></div><div><h3>Results</h3><p>Among the 1361 patients evaluated, 63.8 % were found to be at an increased risk for DFU. The reported prevalence of foot deformities, LOPS, PAD, and a history of foot ulcer was 91.9 %, 44.3 %, 36.5 %, and 4.5 %, respectively. In the adjusted analysis, factors significantly associated with DFU risk included male gender (OR =2.01; 95 % IC 1.54–2.61), secondary education or less (OR =1.65, 95 % IC 1.27–2.14), diabetes duration exceeding 10 years (OR = 1.75, 95 % IC 1.34–2.30), chronic kidney disease (OR =1.44, 95 % IC 1.11 – 1.88), diabetic retinopathy (OR =1.93, 95 % IC 1.42–2.62), onychomycosis (OR =1.46, 95 % IC 1.14–1.88) properly cut toenails (OR =0.60, 95 % IC 0.45–0.79), and sedentary behavior (OR =1.56, 95 % IC 1.14–2.14).</p></div><div><h3>Conclusions</h3><p>Risk assessment of DFU within a comprehensive care program for adults with T2D receiving conventional primary care showed that a substantial proportion of these patients are at an increased risk and, thus, qualify as candidates for interventions aimed at mitigating foot-related risks. We recommend that diabetes healthcare schemes incorporate preventive organizational interventions to facilitate the timely identification of DFU risk, particularly in primary care scenarios, thereby alleviating the burden of diabetes-related lower limb complications.</p></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"14 ","pages":"Article 100195"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666970623000744/pdfft?md5=9f5c6cd41e5663aece0dffb5cd9fe1b5&pid=1-s2.0-S2666970623000744-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139194685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}