Comparative biochemistry and physiology. C: Comparative pharmacology最新文献_第9页

Involvement of eicosanoids and inositol 1,4,5-trisphosphate in serotonin-induced secretion in rat ileum in vivo 二十烷酸和肌醇1,4,5-三磷酸参与体内大鼠回肠血清素诱导分泌

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-05-01 DOI: 10.1016/0742-8413(93)90061-O

Mark Berner Hansen, Bernard M. Jaffe

引用次数: 11

Metabolism of di-, tri- and tetrabromobiphenyls by hepatic microsomes isolated from control animals and animals treated with aroclor 1254, a commercial mixture of polychlorinated biphenyls (PCBs) 对照动物和经多氯联苯(PCBs)混合物aroclor 1254处理的动物肝脏微粒体对二、三、四溴联苯的代谢

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-05-01 DOI: 10.1016/0742-8413(93)90065-S

J.T. Borlakoglu , J.P.G. Wilkins

引用次数: 0

Lipid and amino acid changes in the mussel Pseudoanodonta complanata caused by water pollution 水体污染对拟南齿贻贝脂质和氨基酸的影响

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-05-01 DOI: 10.1016/0742-8413(93)90054-O

K. Stefanov , B. Budevska , O. Ivanov , N. Genov , St. Andreev , S. Popov

引用次数: 1

Effect of high concentration of ammonia on cultured hepatocytes of eel (Anguilla japonica) 高浓度氨对鳗鲡肝细胞培养的影响

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-05-01 DOI: 10.1016/0742-8413(93)90051-L

Seiichi Hayashi , Min-Qian Tang , Takehiko Hirakawa , Shoji Yamada

引用次数: 2

The effects of synthetic thymopoietin on binding of α-bungarotoxin to rat neural membranes 合成胸腺生成素对α-兔毒与大鼠神经膜结合的影响

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-03-01 DOI: 10.1016/0742-8413(93)90010-I

K.R. Jennings , H.M. Shieh

引用次数: 1

Effects of cadmium on sterol composition in the aboral body-wall of the sea star asterias rubensl. 镉对星形海星体外体壁甾醇组成的影响。

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-03-01 DOI: 10.1016/0742-8413(93)90011-9

P.A. Voogt , B. Bissumbhar , T.M. Idzinga , H.J. Wynne , M. Jansen

{"title":"Effects of cadmium on sterol composition in the aboral body-wall of the sea star asterias rubensl.","authors":"P.A. Voogt , B. Bissumbhar , T.M. Idzinga , H.J. Wynne , M. Jansen","doi":"10.1016/0742-8413(93)90011-9","DOIUrl":"10.1016/0742-8413(93)90011-9","url":null,"abstract":"<div>1. Sterol composition of the aboral body-wall of male specimens of Asterias rubens starved for three weeks, was compared with that of male sea stars which during the starvation period had been exposed to cadmium (100<math><mtext>μg</mtext><mtext>l</mtext></math>).2. Sterol composition of non-exposed animals appeared to be constant as assessed over a period of four years.3. Cadmium-exposure strongly influenced sterol composition. The effect was related to the reproductive cycle, effects being different in the spermatogenic and the aspennatogenic phase.4. Effects on total C27-, C28-,Δ7.22-, and some individual sterols showed abrupt changes in November and March, coinciding with the start and the end of the reproductive cycle.5. In one experiment additional parameters were determined. Cadmium-exposure resulted in a significant increase of polar lipids in the body-wall and a decrease of the sterol/phospholipid ratio. The increase of polar lipids was accompanied by a decrease of C28-sterols. Consequences for viscosity are discussed.6. Cadmium-exposure also resulted in a decrease of phosphatidylserine and an increase of phosphatidylethanolamine.</div>","PeriodicalId":72650,"journal":{"name":"Comparative biochemistry and physiology. C: Comparative pharmacology","volume":"104 3","pages":"Pages 415-421"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0742-8413(93)90011-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54004731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Response of plasma cortisol to environmental cadmium in the eel, Anguilla rostrata lesueur 鳗鲡血浆皮质醇对环境镉的响应

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-03-01 DOI: 10.1016/0742-8413(93)90023-E

T.S. Gill , G. Leitner , S. Porta , A. Epple

引用次数: 36

Toxic oil syndrome: a study of renal function in guinea pigs fed toxic oil 中毒性油综合征:用中毒性油喂养豚鼠肾功能的研究

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-03-01 DOI: 10.1016/0742-8413(93)90019-H

C. Sánchez-Bernal, M. Sánchez-Martín, A.Sánchez Llorente, J.A. Cabezas, N.Pérez González

{"title":"Toxic oil syndrome: a study of renal function in guinea pigs fed toxic oil","authors":"C. Sánchez-Bernal, M. Sánchez-Martín, A.Sánchez Llorente, J.A. Cabezas, N.Pérez González","doi":"10.1016/0742-8413(93)90019-H","DOIUrl":"10.1016/0742-8413(93)90019-H","url":null,"abstract":"<div>1. Comparative studies of β-N-acetylglucosaminidase (NAG, EC 3.2.1. 52) and β-galactosidase (EC 3.2.1.23) activities, protein concentration and creatinine clearance, were carried out in urine and kidney from guinea pigs treated with “toxic oil”, orally administered under different conditions, related to controls.2. Enzyme activities did not vary significantly in urine with any of the studied conditions of oil administration. By contrast, in kidney, β-d-galactosidase disclosed a significant increase in all the treatments studied when compared to controls without treatment.3. Urinary protein excretion, creatinine concentration and creatinine clearance were significantly greater in treated animals than in controls after 4 weeks of treatment.4. Relative kidney weight (<math><mtext>g</mtext><mtext>100</mtext></math> g body wt), was significantly lower in animals treated for 28 days with previously heated oil.</div>","PeriodicalId":72650,"journal":{"name":"Comparative biochemistry and physiology. C: Comparative pharmacology","volume":"104 3","pages":"Pages 463-468"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0742-8413(93)90019-H","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19096416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Comparative studies on lipid peroxidation and DNA-single strand breaks induced by lindane, DDT, chlordane and endrin in rats 林丹、滴滴涕、氯丹和内啡肽诱导大鼠脂质过氧化和dna单链断裂的比较研究

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-03-01 DOI: 10.1016/0742-8413(93)90013-B

E. Hassoun, M. Bagchi, D. Bagchi, S.J. Stohs

{"title":"Comparative studies on lipid peroxidation and DNA-single strand breaks induced by lindane, DDT, chlordane and endrin in rats","authors":"E. Hassoun, M. Bagchi, D. Bagchi, S.J. Stohs","doi":"10.1016/0742-8413(93)90013-B","DOIUrl":"10.1016/0742-8413(93)90013-B","url":null,"abstract":"<div>1. A variety of structurally dissimilar polyhalogenated cyclic hydrocarbons produce similar toxic effects. The molecular mechanisms involved in the production of these toxic manifestations is not known.2. We have proposed that reactive oxygen species may be involved, and have therefore examined the time-dependent effects of lindane (30<math><mtext>mg</mtext><mtext>kg</mtext></math>), DDT (40 <math><mtext>mg</mtext><mtext>kg</mtext></math>), chlordane (l 20 <math><mtext>mg</mtext><mtext>kg</mtext></math>), and endrin (4.5 <math><mtext>mg</mtext><mtext>kg</mtext></math>) on the production of hepatic mitochondrial and microsomal lipid peroxidation and DNA single strand breaks, two indices of oxidative stress.3. All four xenobiotics resulted in significant increases in hepatic lipid peroxidation and DNA damage. Earliest (6 hr) increases in both lipid peroxidation and DNA damage were observed following lindane adminstration. Time-dependent increases in both parameters were observed following endrin administration.4. Maximum increases in DNA single strand breaks of 2.8- and 2.5-fold were observed 12 hr after DDT and chlordane administration, respectively, while a 4.4-fold increase was observed 24 hr after endrin adminstration.5. The results demonstrate that the four structurally dissimilar polyhalogenated hydrocarbons produce oxidative tissue damage which may contribute to the toxic manifestations of these xenobiotics, and exhibit different toxicokinetic properties.</div>","PeriodicalId":72650,"journal":{"name":"Comparative biochemistry and physiology. C: Comparative pharmacology","volume":"104 3","pages":"Pages 427-431"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0742-8413(93)90013-B","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18692914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 53

Distribution and immunochemical characteristics of neuropeptide F (NPF) (Moniezia expansa)—immunoreactivity in Proteocephalus pollanicola (Cestoda: proteocephalidea) 神经肽F (NPF)(扩张Moniezia expansa) -免疫反应性在白头翁体内的分布及免疫化学特征

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-03-01 DOI: 10.1016/0742-8413(93)90004-5

N.J. Marks , A.G. Maule , D.W. Halton , C. Shaw , C.F. Johnston

{"title":"Distribution and immunochemical characteristics of neuropeptide F (NPF) (Moniezia expansa)—immunoreactivity in Proteocephalus pollanicola (Cestoda: proteocephalidea)","authors":"N.J. Marks , A.G. Maule , D.W. Halton , C. Shaw , C.F. Johnston","doi":"10.1016/0742-8413(93)90004-5","DOIUrl":"10.1016/0742-8413(93)90004-5","url":null,"abstract":"<div>1. Using immunocytochemical techniques and confocal scanning laser microscopy, the proteocephalidean cestode, Proteocephalus pollanicola from Lough Neagh pollan (Coregonus autumnalis) was examined for the presence of the native platyhelminth neuropeptide, neuropeptide F (NPF).2. An antiserum specific for whole-molecule NPF(1–39) (Moniezia expansa) did not immunostain nerve processes in P. pollanicola. A C-terminally-directed NPF(30–39) (M. expansa) antiserum immunostained nerve fibres and cell bodies of both the central and peripheral nervous systems, including innervation associated with the female reproductive system.3. The pattern of immunoreactivity was identical to that obtained using antisera to the C-terminal region of mammalian NPY-superfamily peptides and the invertebrate neuropeptide, FMRFamide.4. Under radioimmunoassay conditions, only the C-terminally-directed NPF antiserum cross-reacted with the P. pollanicola peptide and detected 58.74 <math><mtext>ng</mtext><mtext>g</mtext></math> wet weight of NPF-IR in extracts of the worm.5. Chromatographic characterisation of P. pollanicola NPF-immunoreactivity indicated an apparent molecular weight of 4400–4700 Da, similar to that of NPF (M. expansa).6. Further analytical HPLC characterisation identified two molecular forms of P. pollanicola NPF-immunoreactivity, both of which had different retention times from those of NPF (M. expansa) and NPF (Artioposthia triangulata).7. These data suggest that P. pollanicola possesses a neuropeptide which is homologous in its C-terminal region to NPF (M. expansa) but diners in its mid- to N-terminal region.</div>","PeriodicalId":72650,"journal":{"name":"Comparative biochemistry and physiology. C: Comparative pharmacology","volume":"104 3","pages":"Pages 381-386"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0742-8413(93)90004-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19096463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17