Thomas Gladytz, Kathleen Cantow, Jason M Millward, Sonia Waiczies, Ehsan Tasbihi, Dirk Grosenick, Erdmann Seeliger, Thoralf Niendorf
{"title":"MRI-PHYSIOL-NIRS: an integrated platform to study kidney oxygenation.","authors":"Thomas Gladytz, Kathleen Cantow, Jason M Millward, Sonia Waiczies, Ehsan Tasbihi, Dirk Grosenick, Erdmann Seeliger, Thoralf Niendorf","doi":"10.1038/s44172-026-00799-x","DOIUrl":"10.1038/s44172-026-00799-x","url":null,"abstract":"<p><p>The kidney always operates close to hypoxia, a pathological condition of O<sub>2</sub>-shortage, due to its unique relationship between blood flow and oxygen demand. Renal hypoxia is central to kidney diseases, where progressive loss of renal function ultimately can no longer sustain life. Magnetic resonance imaging (MRI) can assess renal oxygenation non-invasively in vivo via the relaxation times T<sub>2</sub><sup>*</sup> and T<sub>2</sub>, which reflect deoxygenated hemoglobin, but are influenced by several physiological confounders. We developed MRI-PHYSIOL-NIRS, a platform integrating MRI with ground-truth probes that directly measure tissue oxygenation in rat kidneys (PHYSIOL), and near-infrared spectroscopy (NIRS) to estimate oxygenation-related parameters to dissect the relationship between MRI-based measures and true tissue oxygenation. Using aortic occlusion and hyperoxia interventions within the MRI scanner, we investigated correlations between non-invasive MRI-based oxygenation measures and true tissue oxygenation. These results demonstrate the potential for entirely MRI-based measurement of renal oxygenation in health and disease, with ultimate application in patients.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Electronics-free, ultra-low-power, wearable sensor chip for high-frequency electromagnetic field detection.","authors":"Abdul Mohizin, Leon Abelmann, Baeckkyoung Sung","doi":"10.1038/s44172-026-00800-7","DOIUrl":"10.1038/s44172-026-00800-7","url":null,"abstract":"<p><p>High-frequency electromagnetic fields (EMFs) are increasingly recognized either as environmental risk factors or as tools for electromagnetic attacks, which are difficult to detect in situ. Existing high-frequency EMF sensors face significant limitations related to structural simplicity, integration with mobile technology, and low energy consumption. To address these challenges, we propose a miniature sensor concept based on a magnetically hybridized liquid crystal (LC) microdevice. The hybrid LC chip is designed to exhibit an optical response to external radio-frequency fields without the need for electronic components or an external power supply, relying solely on ambient light. Both sides of the chip are covered with polymer-based crossed polarizer films. The chip is filled with flexible matrices containing thermotropic LCs, such as the rod-like 4-cyano-4'-pentylbiphenyl, into which a network of thin ferromagnetic wires is embedded. The resulting field-responsive LC microdisplay operates via a simple magnetothermal mechanism, and its optical response is sufficiently strong to be visible to the naked eye.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13642341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Damiano Padovani, Nasima Afsharimani, Andrea Cioncolini, Yu Ding
{"title":"Hematologic complications and design challenges in cardiovascular devices.","authors":"Damiano Padovani, Nasima Afsharimani, Andrea Cioncolini, Yu Ding","doi":"10.1038/s44172-026-00771-9","DOIUrl":"https://doi.org/10.1038/s44172-026-00771-9","url":null,"abstract":"<p><p>In this review, we provide an engineering assessment of prevalent blood-wetted cardiovascular devices, their hematologic complications, and their interconnections to identify key areas for future research. In fact, the incidence of cardiovascular diseases has promoted the development of various devices to treat these conditions, including mechanical circulatory supports (mechanical pumps that assist or replace failing hearts), artificial valves to replace faulty heart valves, stents to relieve obstructions in blood vessels, vascular grafts to repair/reconstruct damaged vessels, patches to reinforce or reconstruct cardiovascular tissues, and other implants. The hemocompatibility of these cardiovascular devices, namely their ability to interact with blood flow without causing adverse reactions, remains unsatisfactory, and recurrent complications include thrombosis, hemolysis, and bleeding. Therefore, the discussion provided herein will support readers approaching cardiovascular technologies in building a solid foundation and provide everyone with an up-to-date overview of ongoing research in this multidisciplinary field.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Axel Solt-Rindler, Elisabeth Billich, Johanna Sperl, Werner Engel, Bernhard Seifert, Christian Hansmann
{"title":"Space sustainability beyond 'zero debris': from orbital safety to circular materials.","authors":"Axel Solt-Rindler, Elisabeth Billich, Johanna Sperl, Werner Engel, Bernhard Seifert, Christian Hansmann","doi":"10.1038/s44172-026-00797-z","DOIUrl":"10.1038/s44172-026-00797-z","url":null,"abstract":"","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhiyong Feng, Lin Wang, Kan Yu, Zhiqing Wei, Qixun Zhang, Dingyou Ma, Jiapeng Li, Jiachen Wei, Ping Zhang
{"title":"Communication-infrastructure-enabled ISAC for low-altitude sensing.","authors":"Zhiyong Feng, Lin Wang, Kan Yu, Zhiqing Wei, Qixun Zhang, Dingyou Ma, Jiapeng Li, Jiachen Wei, Ping Zhang","doi":"10.1038/s44172-026-00754-w","DOIUrl":"10.1038/s44172-026-00754-w","url":null,"abstract":"<p><p>As a core infrastructure of modern information society, cellular networks have long supported terrestrial communications and are now being extended to low-altitude connectivity with the growth of the low-altitude economy. However, the increasing number of aerial vehicles poses new challenges to airspace supervision and flight safety, creating a need for wide-area, continuous and accurate sensing. Conventional sensing devices, such as dedicated radars and cameras, can provide target information but suffer from high deployment cost, electromagnetic interference, and complex coordination. By exploiting the similarities between communication and radar systems in electromagnetic propagation, hardware and signal processing, integrated sensing and communication offers a promising way to reuse communication infrastructure for low-altitude sensing. In this Review, key engineering issues in communication-infrastructure-enabled low-altitude sensing are discussed, including base station deployment, sensing mode design, synchronization and waveform design. Enabling techniques for target detection, localization, tracking and recognition are further summarized, with emphasis on communication-adapted signal processing, networked sensing, and multimodal fusion. Experimental demonstrations and future directions in weather monitoring, data security and privacy protection are also discussed.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Poroelastic strain precursors during laboratory carbon dioxide core flooding revealed by helically bonded fiber sensing.","authors":"Jinrong Cao, Hyuck Park, Ziqiu Xue, Takahiro Nakajima, Rasha Amer, Wataru Ouchi","doi":"10.1038/s44172-026-00783-5","DOIUrl":"10.1038/s44172-026-00783-5","url":null,"abstract":"<p><p>Reliable monitoring of carbon dioxide injection requires observations of both plume migration and the associated geomechanical deformation. Using a laboratory supercritical carbon dioxide core-flooding experiment, we show that circumferential strain measured by a helically bonded fiber evolves differently in space and time from carbon dioxide saturation imaged by time-lapse X-ray computed tomography. The associated coupled two-phase flow and poroelastic deformation modeling, constrained by the tomography-derived saturation data, indicates that strain changes precede the carbon dioxide saturation front as they closely follow pressure disturbances propagating through the connected water phase. Later strain evolution increasingly reflects capillary-controlled carbon dioxide invasion. Because pressure inside porous rock is difficult to measure directly at high spatial resolution, we interpret distributed strain as a model-constrained poroelastic proxy for the evolving pressure footprint. Overall, our results show that distributed strain sensing can identify mechanically affected regions ahead of the carbon dioxide plume front, when these measurements are supported by saturation imaging and sparse pressure gauge information.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13612393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149042217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Time-frequency gated transformer for structural dynamic response reconstruction.","authors":"Xueli Song, Fan Yang, Rongpeng Li, Xiao Ma, Yilin Wang, Shuyi Wang, Qingtian Deng, Supei Zheng","doi":"10.1038/s44172-026-00788-0","DOIUrl":"10.1038/s44172-026-00788-0","url":null,"abstract":"<p><p>Structural dynamic response reconstruction is of significant importance because data incompleteness critically undermines the reliability of structural health monitoring. Existing deep-learning reconstruction methods focus solely on the time-domain features of structural dynamic responses and neglect their frequency-domain counterpart. This reduces their reconstruction accuracy because the frequency-domain features directly reflect the inherent dynamic characteristics of structures. To address this problem, we propose a time-frequency gated transformer (TFGFormer) leveraging both the time-domain and frequency-domain features. Specifically, multi-scale dilated transformers and dense blocks are respectively used to extract the time-domain global and local features because the former sparsely encode long-range dependencies and the latter aggregate multi-layer representations. Concurrently, frequency modules are used to extract the frequency-domain features because they are able to adaptively learn the spectral complex-valued weights. Finally, gate modules and a joint time-frequency loss function are used to adaptively fuse these features because the former balance dynamically their contributions and the latter simultaneously penalizes their residuals. Validated on full-scale field data from the Canton Tower and the Hardanger Bridge, TFGFormer outperforms representative baseline methods across various data-missing scenarios and enjoys zero-shot robustness and lightweight design. This reconstruction-oriented time-frequency framework may support more reliable downstream SHM tasks.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yan Xiang, Yakun Wang, Bo Dai, Zhe Chen, Yantao Zhu, Guangze Shen, Jiang Hu, Siyu Chen
{"title":"Underwater detection and repair reinforcement technologies for reservoir-dam systems: development status and research challenges.","authors":"Yan Xiang, Yakun Wang, Bo Dai, Zhe Chen, Yantao Zhu, Guangze Shen, Jiang Hu, Siyu Chen","doi":"10.1038/s44172-026-00781-7","DOIUrl":"10.1038/s44172-026-00781-7","url":null,"abstract":"<p><p>The long-term structural integrity of reservoir-dam systems is essential for ensuring water security, energy supply, and public safety. Underwater structural defects, driven by complex hydraulic and environmental conditions, pose growing threats to the safe operation of large dams. In recent decades, significant progress has been made in underwater inspection, defect detection, and repair technologies, offering viable alternatives to traditional drawdown-based maintenance. This review systematically synthesizes advances in underwater detection and rehabilitation technologies for reservoir-dam systems, focusing on inspection platforms, positioning and navigation methods, defect identification techniques, and underwater repair materials. It critically examines key challenges, including limited transferability of marine-derived technologies, environmental interference, cumulative operational errors, and real-world applicability. This paper further categorizes existing technologies by maturity and proposes problem-oriented research directions to support the development of intelligent, reliable, and field-deployable systems for underwater defect management in large dams.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13594326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149018909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert Wendland, Felix Schmieder, Muhammad Atif Sikandar, Frithjof Paul Knüppel, Wolfram-Hubertus Zimmermann, Olaf Bergmann, Lars Büttner, Jürgen W Czarske
{"title":"All-optical closed-loop control of human cardiomyocyte networks exploiting holographic optogenetics.","authors":"Robert Wendland, Felix Schmieder, Muhammad Atif Sikandar, Frithjof Paul Knüppel, Wolfram-Hubertus Zimmermann, Olaf Bergmann, Lars Büttner, Jürgen W Czarske","doi":"10.1038/s44172-026-00779-1","DOIUrl":"10.1038/s44172-026-00779-1","url":null,"abstract":"<p><p>Heart diseases can trigger life-threatening arrhythmias by disrupting cardiac contraction wavefront propagation. In contrast to conventional treatments like electrical pacemakers, optogenetics offers high spatial and temporal resolution for non-invasive interrogation and modulation of cellular activity. However, combining sensing and actuation into a real-time control loop remains challenging. A major obstacle is the data load associated with dense sensor arrays typically required for spatially resolved wavefront monitoring. To overcome this, we present an all-optical, closed-loop control strategy using adaptive holographic stimulation and sparsely sampled, label-free imaging data, enabling robust classification and quantitative characterization of spatial wavefront properties in real time. We successfully demonstrate spatiotemporal optogenetic closed-loop control of wavefront dynamics in functional syncytia of human induced pluripotent stem cell-derived cardiomyocytes in at least 107 out of 109 evaluated cases across all experiments. This framework establishes a foundation for advanced feedback control strategies aimed at mimicking, detecting and terminating abnormal propagation patterns.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chengyao Shi, Laura Nuttin, Zhenyu Gao, Yuming He, Pietro Russo, Hua-Peng Liaw, Marios Gourdouparis, Dennis Lambrechts, Guido Dolmans, Yao-Hong Liu
{"title":"An Event based Body Coupled Transdural Telemetry for Intracortical Brain Computer Interfaces.","authors":"Chengyao Shi, Laura Nuttin, Zhenyu Gao, Yuming He, Pietro Russo, Hua-Peng Liaw, Marios Gourdouparis, Dennis Lambrechts, Guido Dolmans, Yao-Hong Liu","doi":"10.1038/s44172-026-00735-z","DOIUrl":"10.1038/s44172-026-00735-z","url":null,"abstract":"<p><p>Intracortical brain-computer interfaces (iBCIs) hold promise for restoring motor, sensory, and cognitive functions, including applications in paralysis treatment and speech decoding. High-density microelectrode arrays (MEAs) provide fine spatial and temporal discrimination of neural activity, but the considerable upsurge in data generation poses challenges for wireless transmission from miniaturized implants due to constraints on power, bandwidth, heat dissipation, and device size. To address these constraints, we propose a two-stage wireless iBCI architecture comprising a transdural galvanic-coupled body channel communication (BCC) link from a free-floating MEA to an intracranial unit, followed by a transcutaneous link to an external unit. This study focuses on the transdural BCC telemetry system, which provides compact, wideband, and energy-efficient data transmission. Phantom tests, and ex vivo experiments using a human cadaveric head specimen validate the system, demonstrating wireless transmission up to 500 Mbps with 20% duty cycling and bit error rates below 10⁻⁵. The system incorporates the send-on-delta encoder (SODA), achieving up to 11.4× data compression and reducing thermal load for meeting the safety guidelines. Safety is further examined using brain-on-a-chip models, which demonstrate that the system does not evoke unintended neural activity, supporting the platform's long-term viability for high-resolution iBCIs.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"5 1","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13534433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}