Acupuncture in Medicine最新文献

筛选
英文 中文
Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial. 针灸治疗复发缓解型多发性硬化症患者疲劳的有效性:一项随机对照试验。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-08-01 DOI: 10.1177/09645284221150824
Faezeh Khodaie, Abdorreza Naser Moghadasi, Amir Hooman Kazemi, Baixiao Zhao
{"title":"Effectiveness of acupuncture for fatigue in patients with relapsing-remitting multiple sclerosis: a randomized controlled trial.","authors":"Faezeh Khodaie,&nbsp;Abdorreza Naser Moghadasi,&nbsp;Amir Hooman Kazemi,&nbsp;Baixiao Zhao","doi":"10.1177/09645284221150824","DOIUrl":"https://doi.org/10.1177/09645284221150824","url":null,"abstract":"<p><strong>Background: </strong>Fatigue is experienced by more than 65% of individuals with multiple sclerosis (MS). Some studies have supported the effectiveness of acupuncture in improving the symptoms of MS.</p><p><strong>Objective: </strong>The present research was intended to investigate the effectiveness of acupuncture plus amantadine compared with amantadine alone on fatigue in patients with relapsing-remitting MS (RRMS) in the remission stage of the disease.</p><p><strong>Methods: </strong>In this randomized controlled trial, 60 participants with RRMS suffering from fatigue were recruited and randomized equally to acupuncture (n = 30) and control (n = 30) groups. The acupuncture group received treatment 2 to 3 times per week for 10 sessions over 4 weeks. Both the acupuncture and control groups received amantadine 100 mg daily and routine treatment with immuno-modulators. The primary outcome was the fatigue severity scale (FSS) score, which was evaluated at baseline, and after 2 and 4 weeks. The secondary outcome was the Multiple Sclerosis Quality of Life 54 (MSQOL-54) questionnaire score, measured at baseline and the end of the 4-week treatment period.</p><p><strong>Results: </strong>The severity of fatigue was reduced in both groups. However, after 4 weeks of treatment, the reduction of fatigue in the acupuncture group was more significant than in the control group (<i>P</i> < 0.01, mean difference (MD) = -1.14, 95% confidence interval (CI): -1.83 to -0.45). Quality of life, including mental and physical status, was significantly improved in the acupuncture group compared with the control group (<i>P</i> < 0.05, MD = 9.09, 95% CI: 0.46 to 17.73). No adverse events occurred in any of the participants.</p><p><strong>Conclusions: </strong>Acupuncture combined with amantadine and routine care compared with amantadine and routine care alone appears to be an effective short-term treatment for reducing fatigue and enhancing quality of life, including physical function and mental status, in patients with RRMS.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 4","pages":"199-205"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9842629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of acupuncture on microglial polarization and the TLR4/TRIF/MyD88 pathway in a rat model of traumatic brain injury. 针刺对创伤性脑损伤大鼠小胶质细胞极化及TLR4/TRIF/MyD88通路的影响
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-08-01 DOI: 10.1177/09645284221108214
Lu-Xi Cao, Shu-Jun Lin, Si-Si Zhao, Shi-Qi Wang, Hai Zeng, Wen-An Chen, Zhuo-Wen Lin, Jia-Xu Chen, Ming-Min Zhu, Yi-Min Zhang
{"title":"Effects of acupuncture on microglial polarization and the TLR4/TRIF/MyD88 pathway in a rat model of traumatic brain injury.","authors":"Lu-Xi Cao,&nbsp;Shu-Jun Lin,&nbsp;Si-Si Zhao,&nbsp;Shi-Qi Wang,&nbsp;Hai Zeng,&nbsp;Wen-An Chen,&nbsp;Zhuo-Wen Lin,&nbsp;Jia-Xu Chen,&nbsp;Ming-Min Zhu,&nbsp;Yi-Min Zhang","doi":"10.1177/09645284221108214","DOIUrl":"https://doi.org/10.1177/09645284221108214","url":null,"abstract":"<p><strong>Objective: </strong>Neuroinflammation caused by traumatic brain injury (TBI) can lead to neurological deficits. Acupuncture can inhibit neuroinflammation and promote nerve repair; however, the specific mechanism is still unclear. The purpose of this study was to explore whether acupuncture could modulate the M1 and M2 phenotypic polarization of microglia in a rat model of TBI via the toll-like receptor 4 (TLR4)/intracellular toll-interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)/myeloid differentiation factor 88 (MyD88) pathway.</p><p><strong>Methods: </strong>A total of 90 adult male Sprague-Dawley (SD) rats, SPF grade, were randomly divided into a normal group, model group and acupuncture group. Each group was further divided into three subgroups (first, third, and fifth day groups) according to the treatment time (<i>n</i> = 10 rats/subgroup). We used the modified neurological severity score (mNSS) method to quantify neurological deficits before and after modeling. We used Nissl staining to observe the pathological changes in brain tissue, flow cytometry to detect the proportion of M1 and M2 polarized microglia in the injured area on the first, third and fifth day, and co-immunoprecipitation (Co-IP) to examine TLR4/TRIF/MyD88 expression in microglia on the first, third and fifth day, as well as expression of the amount of binding of TLR4 with TRIF and MyD88.</p><p><strong>Results: </strong>Compared to the model group, mNSS in the acupuncture group gradually decreased and pathological morphology improved. The proportion of CD11b/CD86 positive cells was decreased, while that of CD11b/CD206 was increased in the acupuncture group. Expression of IP TLR4, IP TRIF and IP MyD88 also decreased in the acupuncture group.</p><p><strong>Conclusion: </strong>The results of this study demonstrate that one of the mechanisms through which acupuncture mitigates neuroinflammation and promotes nerve repair in TBI rats may be inhibition of M1 phenotypic polarization and promotion of M2 phenotypic polarization through inhibition of the TLR4/TRIF/MyD88 signaling pathway.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 4","pages":"235-245"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9784810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effects of electroacupuncture on liver function in mice with chronic alcoholic liver injury: visual display by in vivo fluorescence imaging. 电针对慢性酒精性肝损伤小鼠肝功能的影响:体内荧光成像的视觉显示。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-08-01 DOI: 10.1177/09645284221125248
Xiao-Jing Song, Shu-You Wang, Shu-Yong Jia, Guang-Jun Wang, Wei-Bo Zhang
{"title":"Effects of electroacupuncture on liver function in mice with chronic alcoholic liver injury: visual display by <i>in vivo</i> fluorescence imaging.","authors":"Xiao-Jing Song,&nbsp;Shu-You Wang,&nbsp;Shu-Yong Jia,&nbsp;Guang-Jun Wang,&nbsp;Wei-Bo Zhang","doi":"10.1177/09645284221125248","DOIUrl":"https://doi.org/10.1177/09645284221125248","url":null,"abstract":"<p><strong>Objective: </strong>Acupuncture can improve the symptoms of alcohol-induced bodily injury and has been accepted by the World Health Organization. In this study, <i>in vivo</i> fluorescence imaging (IVFI) was applied to display and evaluate the effect of electroacupuncture (EA) on liver function (LF) in mice with chronic alcoholic liver injury (cALI).</p><p><strong>Methods: </strong>IVFI of the Cy5.5-galactosylated polylysine (Cy5.5-GP) probe targeting the liver asialoglycoprotein receptor (ASGPR) and liver indocyanine green (ICG) clearance was performed to visually evaluate the effect of EA at ST36 and BL18 on liver reserve function and hepatic metabolism in mice with cALI. In addition, changes in ASGPR expression, serum indexes of LF, and hepatic morphology were observed.</p><p><strong>Results: </strong>After EA at ST36 and BL18, the ASGPR-targeted fluorescence signals (FS) in the liver increased significantly in cALI mice (<i>p</i> < 0.05) and exhibited relationships with liver ASGPR expression, liver ICG clearance, liver histology, and serum marker levels of LF in cALI mice undergoing EA intervention.</p><p><strong>Conclusions: </strong>As displayed by IVFI, EA at ST36 and BL18 appears to improve liver reserve function and inhibit the development of liver injury in mice with cALI. EA may have potential as a treatment strategy to protect against ALI.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 4","pages":"215-223"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9841013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electroacupuncture relieves visceral hypersensitivity through modulation of the endogenous cannabinoid system. 电针通过调节内源性大麻素系统减轻内脏过敏。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-08-01 DOI: 10.1177/09645284221107699
Ning Ma, Xiaojing Li, Qiuhua Li, Diqi Yang, Shen Zhuang, Sha Nan, Ai Liu, Mingxing Ding, Yi Ding
{"title":"Electroacupuncture relieves visceral hypersensitivity through modulation of the endogenous cannabinoid system.","authors":"Ning Ma,&nbsp;Xiaojing Li,&nbsp;Qiuhua Li,&nbsp;Diqi Yang,&nbsp;Shen Zhuang,&nbsp;Sha Nan,&nbsp;Ai Liu,&nbsp;Mingxing Ding,&nbsp;Yi Ding","doi":"10.1177/09645284221107699","DOIUrl":"https://doi.org/10.1177/09645284221107699","url":null,"abstract":"<p><strong>Background: </strong>Electroacupuncture (EA) can effectively relieve visceral hypersensitivity (VH). However, its mechanisms are still unclear.</p><p><strong>Objective: </strong>To investigate the impact of EA on VH caused by ileitis, and whether EA relieves VH by modulating the endogenous cannabinoid system (ECS).</p><p><strong>Methods: </strong>Thirty male native goats were randomly divided into a saline-treated control group (Saline, n = 9) and three 2,4,6-trinitro-benzenesulfonic acid (TNBS)-treated VH model groups that underwent injection of TNBS into the ileal wall to induce VH and remained untreated (TNBS, n = 9) or received six sessions of EA (for 30 min every 3 days) (TNBS + EA, n = 6) or sham acupuncture (TNBS + Sham, n = 6). The visceromotor response (VMR) to colorectal distention (CRD) was measured after each EA treatment. Three goats in the Saline/TNBS groups were euthanized after 7 days for histopathological examination; the remaining 24 (n = 6/group) underwent sampling of the ileal wall, T11 spinal cord and brain nuclei/areas related to visceral regulation and ascending pain modulation system on day 22. Expression of cannabinoid receptor 1 (CB1R), fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) was detected by immunohistochemistry.</p><p><strong>Results: </strong>VMR to CRD was greater in TNBS-treated goats than in saline-treated goats (p < 0.01) from day 7 to 22. After day 7, EA-treated goats showed a decreased (p < 0.05) VMR compared with untreated TNBS-exposed goats. TNBS treatment decreased CB1R and increased FAAH and MAGL expression in the ileum and related nuclei/areas; this was reversed by EA.</p><p><strong>Conclusion: </strong>EA ameliorates VH, probably by regulating the ECS in the intestine and nuclei/areas related to visceral regulation and descending pain modulation systems.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 4","pages":"224-234"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9785632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Acupuncture targeting the minor salivary glands for dry mouth: a case report. 针刺小唾液腺治疗口干1例。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-06-01 DOI: 10.1177/09645284221131340
Nobuari Takakura, Takahiro Yamada, Tomohiro Tanaka, Marina Yokouchi, Miho Takayama, Judith M Schlaeger, Hiroyoshi Yajima
{"title":"Acupuncture targeting the minor salivary glands for dry mouth: a case report.","authors":"Nobuari Takakura,&nbsp;Takahiro Yamada,&nbsp;Tomohiro Tanaka,&nbsp;Marina Yokouchi,&nbsp;Miho Takayama,&nbsp;Judith M Schlaeger,&nbsp;Hiroyoshi Yajima","doi":"10.1177/09645284221131340","DOIUrl":"https://doi.org/10.1177/09645284221131340","url":null,"abstract":"Two distressing symptoms of Sjögren’s syndrome are dry mouth and dry eyes, but to date no cure has been established.1 Xerostomia, caused by decreased production of saliva, leads to reduced quality of life, with oral discomfort and dryness leading to excessive drinking of fluids, difficulty speaking and weight loss due to difficulty swallowing food. Herein, we explored acupuncture as an alternative treatment approach for xerostomia in a patient with Sjögren’s syndrome who had not responded to pharmacotherapy.","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 3","pages":"192-194"},"PeriodicalIF":2.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9988268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of trigger point acupuncture on pain and functional activity in patients with chronic non-specific low back pain: a randomised controlled trial. 触发点针刺对慢性非特异性腰痛患者疼痛和功能活动的影响:一项随机对照试验。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-06-01 DOI: 10.1177/09645284221107685
Hong Liu, Ya-Ping Li, Mei-Jin Hou, Wu-Jie Huang, Xiao-Lin Chen, Zhen Gao, Zheng Jiang
{"title":"Effect of trigger point acupuncture on pain and functional activity in patients with chronic non-specific low back pain: a randomised controlled trial.","authors":"Hong Liu,&nbsp;Ya-Ping Li,&nbsp;Mei-Jin Hou,&nbsp;Wu-Jie Huang,&nbsp;Xiao-Lin Chen,&nbsp;Zhen Gao,&nbsp;Zheng Jiang","doi":"10.1177/09645284221107685","DOIUrl":"https://doi.org/10.1177/09645284221107685","url":null,"abstract":"<p><strong>Background: </strong>Trigger point (TrP) acupuncture is commonly used to treat chronic non-specific low back pain (CNLBP). Evidence for the efficacy of most TrP acupuncture modalities is weak or lacking.</p><p><strong>Objective: </strong>To assess the effect of TrP acupuncture on pain, disability, gait and muscle activation in patients with CNLBP.</p><p><strong>Methods: </strong>From May 2019 to February 2020, a randomised, single-blind clinical trial was carried out involving 33 participants with CNLBP, divided into one of two intervention groups or a control group (<i>n</i> = 11 per group). The intervention groups received TrP acupuncture or traditional acupuncture treatment three times a week for 4 weeks, and the control group remained on a waiting list and received no treatment. Pain, disability, gait and muscle activation were assessed at baseline and at 4 and 8 weeks of follow-up.</p><p><strong>Results: </strong>At baseline, the three groups showed no significant differences in age, gender, height, weight, body mass index (BMI) or disease course (<i>p</i> ⩾ 0.05). At 4 weeks, pain was relieved (measured by visual analogue scores, <i>p</i> = 0.036) and disability was improved (reflected by lower Oswestry disability index scores, <i>p</i> = 0.029) in TrP acupuncture versus waiting list groups. Moreover, lumbar extension range of motion was increased in TrP acupuncture versus both traditional acupuncture and waiting list groups (<i>p</i> = 0.029 and <i>p</i> = 0.027, respectively). At 8 weeks, there were no significant differences in any parameter between the three groups (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>TrP acupuncture had a significant short-term effect on pain relief and disability in patients with CNLBP, but there was no evidence of a long-term influence (at 8 weeks following the intervention). Further high-quality randomised controlled trials are needed for verification in the future.<b>Trial registration number:</b> ChiCTR1900022838 (Chinese Clinical Trial Registry).</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 3","pages":"130-141"},"PeriodicalIF":2.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9669422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in stiffness at active myofascial trigger points of the upper trapezius after dry needling in patients with chronic neck pain: a randomized controlled trial. 慢性颈部疼痛患者干针刺后斜方肌上部肌筋膜触发点僵硬度的变化:一项随机对照试验。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-06-01 DOI: 10.1177/09645284221104831
Juan Antonio Valera-Calero, Sandra Sánchez-Jorge, Jorge Buffet-García, Umut Varol, César Fernández-de-Las-Peñas, Javier Álvarez-González
{"title":"Changes in stiffness at active myofascial trigger points of the upper trapezius after dry needling in patients with chronic neck pain: a randomized controlled trial.","authors":"Juan Antonio Valera-Calero,&nbsp;Sandra Sánchez-Jorge,&nbsp;Jorge Buffet-García,&nbsp;Umut Varol,&nbsp;César Fernández-de-Las-Peñas,&nbsp;Javier Álvarez-González","doi":"10.1177/09645284221104831","DOIUrl":"https://doi.org/10.1177/09645284221104831","url":null,"abstract":"<p><strong>Background/objective: </strong>Since, to our knowledge, the effects of dry needling (DN) on active myofascial trigger point (MTrP) stiffness have not been analyzed previously with shear wave elastography (SWE), our aim was to compare the effects of a single session of DN and sham DN applied to the most active MTrP located in the upper trapezius muscle on clinical outcomes.</p><p><strong>Methods: </strong>A randomized, double-blinded sham-controlled trial was conducted; 60 patients were randomized into an experimental (DN) or sham (sham DN) group. Baseline data including sociodemographic and clinical characteristics were collected. SWE and pain pressure thresholds (PPTs) at the MTrP and a control point located 3 cm laterally were the main outcomes assessed before and 10 min after the interventions.</p><p><strong>Results: </strong>Patients receiving DN interventions experienced greater increases in the control point PPTs immediately after receiving the intervention compared with sham DN (<i>p</i> < 0.05), but no differences were found for the MTrP (<i>p</i> > 0.05). Post-intervention PPT improvements were found at both locations for both groups (<i>p</i> < 0.01). No significant changes for either MTrP or control locations were found for SWE outcomes in either group (all <i>p</i>s > 0.05). No significant within-group SWE differences were found in the DN or sham DN groups (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>A single session of DN or sham DN applied to active MTrPs located in the upper trapezius muscle produced no detectable changes in stiffness at the MTrP or control locations. Real DN induced an immediate analgesic response at both MTrP and control locations, while sham DN induced an immediate MTrP response.</p><p><strong>Trial registration number: </strong>NCT04832074 (ClinicalTrials.gov).</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 3","pages":"121-129"},"PeriodicalIF":2.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9614864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Electroacupuncture pretreatment protects septic rats from acute lung injury by relieving inflammation and regulating macrophage polarization. 电针预处理通过减轻炎症和调节巨噬细胞极化对脓毒症大鼠急性肺损伤有保护作用。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-06-01 DOI: 10.1177/09645284221118588
Jun Zhou, Lan Li, Mengjian Qu, Jinqu Tan, Guanghua Sun, Fu Luo, Peirui Zhong, Chengqi He
{"title":"Electroacupuncture pretreatment protects septic rats from acute lung injury by relieving inflammation and regulating macrophage polarization.","authors":"Jun Zhou,&nbsp;Lan Li,&nbsp;Mengjian Qu,&nbsp;Jinqu Tan,&nbsp;Guanghua Sun,&nbsp;Fu Luo,&nbsp;Peirui Zhong,&nbsp;Chengqi He","doi":"10.1177/09645284221118588","DOIUrl":"https://doi.org/10.1177/09645284221118588","url":null,"abstract":"<p><strong>Background: </strong>Macrophage polarization toward the M2 phenotype may attenuate inflammation and have a therapeutic effect in acute lung injury (ALI).</p><p><strong>Objective: </strong>To investigate the role of electroacupuncture (EA) pretreatment on the inflammatory response and macrophage polarization in a septic rat model of lipopolysaccharide (LPS)-induced ALI.</p><p><strong>Methods: </strong>Male Sprague Dawley rats (n = 24) were randomly divided into three groups (n = 8 each): control (Ctrl), ALI (LPS) and pre-EA (LPS + EA pretreatment). ALI and pre-EA rats were injected with LPS via the caudal vein. Pulmonary edema was assessed by left upper pulmonary lobe wet-to-dry (W/D) ratios. Lung injury scores were obtained from paraffin-embedded and hematoxylin and eosin-stained sections of the left lower pulmonary lobe. Inflammatory activation was quantified using serum tumor necrosis factor (TNF)-α, interleukin (IL)-1β, transforming growth factor (TGF)-β and IL-10 levels measured by enzyme linked immunosorbent assay (ELISA). Macrophage phenotype was determined by real-time quantitative polymerase chain reaction (RT-qPCR) and Western blotting.</p><p><strong>Results: </strong>Mean lung W/D ratio was significantly lower and serum IL-1β levels were decreased in pre-EA rats compared to ALI rats (P < 0.05). TNF-α mRNA expression was decreased and mannose receptor (MR) and Arg1 mRNA expression was increased in the lung tissues of pre-EA rats compared to ALI rats (P < 0.01). Arg1 protein expression was similarly increased in the lung tissues of pre-EA rats compared to ALI rats (P < 0.05).</p><p><strong>Conclusion: </strong>EA pretreatment may play a protective role by promoting macrophage polarization to the M2 phenotype in a septic rat model of LPS-induced ALI.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 3","pages":"175-182"},"PeriodicalIF":2.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9607083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Core outcomes were rarely reported overall in systematic reviews on acupuncture for osteoarthritis: a cross-sectional meta-epidemiological study. 在一项横断面荟萃流行病学研究中,针灸治疗骨关节炎的系统综述很少报道核心结果。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-06-01 DOI: 10.1177/09645284221108215
Tengyue Hu, Youlin Long, Rui Chen, Zixin Yang, Liqin Liu, Litao Huang, Jin Huang, Ga Liao, Liang Du
{"title":"Core outcomes were rarely reported overall in systematic reviews on acupuncture for osteoarthritis: a cross-sectional meta-epidemiological study.","authors":"Tengyue Hu,&nbsp;Youlin Long,&nbsp;Rui Chen,&nbsp;Zixin Yang,&nbsp;Liqin Liu,&nbsp;Litao Huang,&nbsp;Jin Huang,&nbsp;Ga Liao,&nbsp;Liang Du","doi":"10.1177/09645284221108215","DOIUrl":"https://doi.org/10.1177/09645284221108215","url":null,"abstract":"<p><strong>Objective: </strong>To identify a comprehensive list of outcomes and explore the reporting rate of core outcome sets (COS) and related factors in systematic reviews (SRs) of acupuncture for osteoarthritis (OA).</p><p><strong>Study design and setting: </strong>Databases were searched for the relative SRs. Descriptive statistics were calculated as frequencies and percentages. Binary logistic regression was used to explore the factors affecting the reporting rate of COS.</p><p><strong>Results: </strong>We included 59 SRs. Outcome measures reported in the SRs were classified into 11 domains and 67 unique outcomes. No SR completely reported COS. In COS released in 2016, 75% of outcomes (6/8) were only reported by ⩽5% SRs. In COS released in 2019, the reporting rate was very low (from 0% to 17%) for 73.3% of outcomes (11/15). SRs published in the most recent 5 years had a significantly greater possibility of reporting COS (odds ratio (OR) = 4.74, 95% confidence interval (CI) = 1.33 to 16.88, <i>p</i> = 0.016).</p><p><strong>Conclusion: </strong>Core outcomes were rarely reported in systematic reviews of acupuncture for OA, with considerable heterogeneity in the use of outcomes. The publication of COS in the COMET (Core Outcome Measures in Effectiveness Trials) database may help promote the reporting of COS. We encourage systematic reviewers to use relevant COS.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 3","pages":"142-150"},"PeriodicalIF":2.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9616129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Perforating globe injury after acupuncture treatment: two cases. 针刺治疗后球穿孔损伤2例。
IF 2.5 3区 医学
Acupuncture in Medicine Pub Date : 2023-06-01 DOI: 10.1177/09645284221131338
Qimiao Wang, Yuanlong Zhang, Xin Wang, Yaju Pang
{"title":"Perforating globe injury after acupuncture treatment: two cases.","authors":"Qimiao Wang,&nbsp;Yuanlong Zhang,&nbsp;Xin Wang,&nbsp;Yaju Pang","doi":"10.1177/09645284221131338","DOIUrl":"https://doi.org/10.1177/09645284221131338","url":null,"abstract":"Acupuncture has a long history of use in the treatment of various eye diseases, such as acquired paralytic strabismus, dry eye and optic atrophy, for which good results have been reported. However, there is an abundance of blood vessels in the eye, and needle penetration into the orbit may potentially puncture these blood vessels. Therefore, acupuncture treatment poses certain risks. Adverse events of acupuncture in ophthalmology have ranged from subcutaneous petechiae to ocular hematoma and even blindness. Ruolin et al.1 observed that the incidence of hematoma in suborbital acupuncture was 0.2%. Zhang and Zhang2 described two cases of anterior chamber hemorrhage and conjunctival hyperemia caused by acupuncture. Some researchers have mentioned puncture of the cornea or lens, resulting in traumatic cataract associated with acupuncture needles.3 Herein, we report two cases of perforating injury of the globe by acupuncture needles resulting in retinal injury.","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 3","pages":"189-191"},"PeriodicalIF":2.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9607615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信