Acupuncture in Medicine最新文献

{"title":"Acupuncture for female sexual dysfunction: a case report.","authors":"Sen-Lin Ye, Yue Feng, Ru-Yi Zhou, Cai-Gui Luo","doi":"10.1177/09645284221125427","DOIUrl":"https://doi.org/10.1177/09645284221125427","url":null,"abstract":"Female sexual dysfunction (FSD) refers to the inability of women to meet their own expectations with respect to their sex lives, resulting in a lack of satisfaction. Typical symptoms include low libido or difficulty with arousal, orgasmic disorders, or painful intercourse. A meta-analysis showed that the prevalence of FSD in premenopausal women is approximately 40.9%, and the prevalence of individual sexual dysfunction is 20.6%–28.2%.1 The most effective treatment method is hormone therapy,2 but this might have detrimental side effects. Although FSD is not life-threatening, it can have a huge negative impact on quality of life. Patients with FSD have a higher prevalence of anxiety and depression than unaffected individuals.3 Accordingly, alternative treatment options with fewer potential side-effects are desirable. Acupuncture, which has minimal side-effects, is widely used in diseases of the genitourinary system. However, there is currently limited evidence to support acupuncture in the treatment of FSD. Here, we describe a case in which a patient with FSD seemed to be successfully treated by acupuncture.","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 1","pages":"55-57"},"PeriodicalIF":2.5,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10539222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroacupuncture attenuates ac4C modification of P16 mRNA in the ovarian granulosa cells of a mouse model premature ovarian failure.","authors":"Zixiang Geng,&nbsp;Peng Liu,&nbsp;Long Yuan,&nbsp;Kaiyong Zhang,&nbsp;Jiajia Lin,&nbsp;Xiaoli Nie,&nbsp;Huiru Jiang,&nbsp;Bingrong Li,&nbsp;Te Liu,&nbsp;Bimeng Zhang","doi":"10.1177/09645284221085284","DOIUrl":"https://doi.org/10.1177/09645284221085284","url":null,"abstract":"<p><strong>Background: </strong>Premature ovarian failure (POF) is a type of pathological aging, which seriously interferes with the fertility of affected women. Electroacupuncture (EA) may have a beneficial effect; however, its mechanism of action is unknown. The purpose of this study was to determine the effect of EA on ovarian function in ovarian granulosa cells (OGCs) in a cyclophosphamide (CTX)-induced mouse model of POF.</p><p><strong>Methods: </strong>Mice were divided into three groups: wild type (WT) group, CTX group and CTX + EA group. EA was administered under isoflurane anesthesia at CV4, ST36 and SP6 for 30 min every 2 days, 2-3 times per week for a total of 4 weeks. Effects of EA on ovarian weight and level of estrogen were examined. The mRNA and protein expression levels of cell cycle-associated proteins were detected and mRNA modifications were analyzed.</p><p><strong>Results: </strong>EA significantly increased ovarian weight and reduced the proportion of atretic follicles in mice with CTX-induced POF (p < 0.05). EA increased the level of estrogen in the peripheral blood of mice and inhibited the modification of total mRNA N4-acetylcytidine (ac4C). A significant increase in the expression of P16 and N-acetyltransferase 10 (NAT10) and a significant decrease in the expression of Cyclin D (CCND1) and cyclin-dependent kinase 6 (CDK6) were observed in the OGCs of POF mice (p<0.05). After EA, P16 and NAT10 expression was decreased, and CCND1 and CDK6 expression was increased. Finally, EA reduced the ac4C modification of P16 mRNA-specific sites in the OGCs of POF mice.</p><p><strong>Conclusion: </strong>This study demonstrated that EA promoted the repair of the ovarian microenvironment by inhibiting the ac4C modification of P16 mRNA to decrease its stability and expression intensity, and by altering the activity of the P16/CDK6/CCND1 axis in OGCs.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 1","pages":"27-37"},"PeriodicalIF":2.5,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10537134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antidepressant effects of acupuncture in a murine model: regulation of neurotrophic factors.","authors":"Teruhisa Yamamoto,&nbsp;Jun Kawanokuchi,&nbsp;Nobuyuki Nagaoka,&nbsp;Ken Takagi,&nbsp;Torao Ishida,&nbsp;Tomoya Hayashi,&nbsp;Ning Ma","doi":"10.1177/09645284221085279","DOIUrl":"https://doi.org/10.1177/09645284221085279","url":null,"abstract":"<p><strong>Background: </strong>GV20 and <i>Yintang</i> are important targets in acupuncture treatment for depression. In this study, we examined the antidepressant effects of simultaneous acupuncture stimulation at GV20 and <i>Yintang</i>.</p><p><strong>Methods: </strong>We compared the antidepressant effects of manual acupuncture (MA) stimulation at GV20 and <i>Yintang</i>, compared to acupuncture stimulation at two control point locations on the back of the mice (overlying the spinal column) and imipramine administration in a forced swimming (FS)-induced mouse model of depression, and examined the mRNA and protein expression of neurotrophic factors, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin (NT)-3, and NT-4/5 in the brains by real-time polymerase chain reaction in two different experimental schedules - preventive (MA given alongside FS modelling) and therapeutic (MA given after FS-induced depression was already established).</p><p><strong>Results: </strong>MA at GV20 and <i>Yintang</i> significantly reduced the immobility time of mice with FS-induced depression in both preventive and therapeutic experimental designs, with effects that were comparable to those of imipramine administration. Immobility time following simultaneous acupuncture stimulation of the two control point locations overlying the spinal column was significantly suppressed only 2 weeks after the start of FS in the preventive effect experiment, and the suppressive effect was significantly lower than that of simultaneous acupuncture stimulation at GV20 and <i>Yintang</i>. In the therapeutic effect experiment, there was no change in the increase in immobility time after the end of FS. MA at GV20 and <i>Yintang</i> significantly increased the expression of BDNF and NT-3 in the preventive evaluation and NGF, BDNF, NT-3, and NT-4/5 in the therapeutic effect evaluation.</p><p><strong>Conclusion: </strong>Our findings suggest that simultaneous acupuncture stimulation at GV20 and <i>Yintang</i> is effective for the prevention and treatment of depression, and the effect likely involves modulation of the expression of multiple neurotrophic factors.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"41 1","pages":"38-47"},"PeriodicalIF":2.5,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10542077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of acute exacerbations of chronic obstructive pulmonary disease with acupuncture during hospitalization: a three-arm double-blinded randomized sham-controlled trial.","authors":"Ilana Levy, Yotam Elimeleh, Sagi Gavrieli, Samuel Attias, Ariel Schiff, Arie Oliven, Elad Schiff","doi":"10.1177/09645284221086293","DOIUrl":"10.1177/09645284221086293","url":null,"abstract":"<p><strong>Background: </strong>Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a healthcare burden. Acupuncture improves dyspnea in patients with chronic obstructive pulmonary disease (COPD) but, to the best of our knowledge, has not been tested in AECOPD. Here, we evaluated the efficacy and safety of true acupuncture added to standard of care (SOC), as compared with both sham procedure plus SOC and SOC only, for the treatment of AECOPD among inpatients.</p><p><strong>Methods: </strong>This double-blinded randomized sham-controlled trial was set in a tertiary hospital in Israel. Patients with a clinical diagnosis of AECOPD were assigned to true acupuncture with SOC, sham procedure with SOC or SOC only. The primary outcome was dyspnea improvement as measured daily by the validated modified Borg (mBorg) scale. Secondary outcomes included improvement of other patient-reported outcomes and physiologic features, as well as duration of hospitalization and treatment failure. Acupuncture-related side effects were evaluated by the validated Acup-AE questionnaire.</p><p><strong>Results: </strong>Seventy-two patients were randomized: 26 to acupuncture treatment, 24 to sham and 22 to SOC only arms. Baseline characteristics were similar in the three groups. A statistically significant difference in dyspnea intensity was found from the first day of evaluation after treatment (p = 0.014) until day 3 after treatment. Similar results were found for sputum production, but no statistical significance was found when comparing physiologic features between the three arms. Acupuncture was not associated with adverse events.</p><p><strong>Conclusion: </strong>Acupuncture seems to be efficacious in the treatment of AECOPD among inpatients hospitalized in internal medicine departments.</p><p><strong>Trial registration number: </strong>NCT03398213 (ClinicalTrials.gov).</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"40 1","pages":"505-515"},"PeriodicalIF":2.4,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41387148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Specification of interventions and selection of controls in randomized controlled trials of acupuncture: a cross-sectional survey.","authors":"Jiali Liu,&nbsp;Ling Li,&nbsp;Xiaochao Luo,&nbsp;Xuan Qin,&nbsp;Ling Zhao,&nbsp;Jiping Zhao,&nbsp;Xu Zhou,&nbsp;Yanmei Liu,&nbsp;Ke Deng,&nbsp;Yu Ma,&nbsp;Kang Zou,&nbsp;Xin Sun","doi":"10.1177/09645284221117848","DOIUrl":"https://doi.org/10.1177/09645284221117848","url":null,"abstract":"<p><strong>Objective: </strong>Specification of interventions and selection of controls are two methodological determinants for a successful acupuncture trial. However, current practice with respect to these two determinants is not fully understood. Thus, we conducted a cross-sectional survey to examine the specification of interventions and selection of controls among published randomized controlled trials (RCTs) of acupuncture.</p><p><strong>Study design and setting: </strong>We searched PubMed for acupuncture RCTs published in core clinical journals and complementary and alternative medicine (CAM) journals from January 2010 to December 2019 (10 years) and included RCTs that assessed treatment effects of acupuncture versus any type of control. We used network meta-analyses to explore whether there were differential treatment effects in patients with chronic pain when using sham acupuncture as a control versus using waiting list or no treatment.</p><p><strong>Results: </strong>Most of the 319 eligible RCTs specified well the style of acupuncture (86.8%), traditional acupuncture point locations (96.2%), type of needle stimulation (90.3%) and needle retention time (85.6%). However, other acupuncture details were less-frequently specified, including response sought (65.5%), needle manipulation (50.5%), number of needle insertions (21.9%), angle and direction of insertion (31.3%), patient posture (32.3%) and co-interventions (22.9%). Sham acupuncture (41.4%) was the most frequently used control, followed by waiting list or no treatment (32.9%). There was no differential treatment effect when using sham acupuncture versus waiting list/no treatment as a control (standardized mean difference = -0.15, 95% confidence interval: -0.91 to 0.62).</p><p><strong>Conclusion: </strong>Over a decade of research practice, important gaps have remained in the specification of acupuncture interventions, including response sought, needle manipulation, and co-interventions. While sham acupuncture has been widely used, waiting list or no treatment may also be considered as an appropriate control.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"40 6","pages":"524-537"},"PeriodicalIF":2.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33447009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture intervention for acute pain in the Emergency Department trial: a consensus process.","authors":"Arya Nielsen, Juli Olson, Megan Quesada, Chongbin Zhu, Erin Raskin, Bobbee Vang, Jeannette Painovich, Megan Scott, Vashir J Xiong, Jeffery A Dusek","doi":"10.1177/09645284221076507","DOIUrl":"10.1177/09645284221076507","url":null,"abstract":"<p><strong>Purpose: </strong>This document describes the consensus process and intervention for a National Institutes of Health (NIH)-funded multi-site feasibility study utilizing acupuncture for <b>ACU</b>te pa<b>I</b>n in <b>T</b>he Emergenc<b>Y</b> Department (ACUITY). The acupuncture intervention is designed to be flexible and responsive to the most common Emergency Department (ED) scenarios, including trauma, acute pain of the low back, abdomen and/or musculoskeletal system, renal colic and headache.</p><p><strong>Background: </strong>Opioids remain a primary treatment for acute ED pain with attendant risk of adverse effects, addiction liability, diversion and death. Effective/safer options for acute pain are needed. Although acupuncture therapy has shown promise for acute pain in the ED alone or in conjunction with usual care, pragmatic trials are needed to obtain definitive and generalizable evidence.</p><p><strong>Methods: </strong>An Acupuncture Advisory Panel was convened that included nine acupuncture experts with 5-44 years of experience in practice and 2-16 years of experience in the acute pain care setting. A modified Delphi process was used with provision of a literature review, surveys of our panel members, three online discussions and email discussion as needed. The STandards for Reporting Interventions in Controlled Trials (STRICTA) checklist was used as a guide.</p><p><strong>Results: </strong>A responsive acupuncture intervention was agreed on for ACUITY. Session forms were fashioned in REDCap (Research Electronic Data Capture program to capture essential treatment data, assess fidelity and inform our design for a future pragmatic multi-site randomized controlled trial (RCT) of acupuncture in the ED, and for use by other future researchers.</p><p><strong>Conclusion: </strong>Development of a responsive manualization intervention provides the appropriate framework for conducting a future, pragmatic, multi-site, definitive RCT of acupuncture in the ED.</p><p><strong>Trial registration number: </strong>NCT04880733 (ClinicalTrials.gov).</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"40 4","pages":"339-346"},"PeriodicalIF":2.5,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10948001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10733825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture treatment for tinea pedis of the foot in a Korean military hospital: a case report","authors":"Byunwoo Son, Hyeonhoon Lee","doi":"10.1177/09645284221086290","DOIUrl":"https://doi.org/10.1177/09645284221086290","url":null,"abstract":"Tinea pedis is a common infectious skin disease in military personnel and is the second most common skin problem in the Korean military.1 Recent management guidelines for tinea pedis suggest the use of antifungal agents and topical antibiotics, which have rarely been reported to induce liver injury and cutaneous adverse events.2 Patients experiencing such reactions may require other treatment options for tinea pedis. Acupuncture treatment has been found to have therapeutic effects on skin diseases such as burns, chilblains, atopic dermatitis and scars.3 In military medicine, acupuncture treatment has been predominantly used for musculoskeletal diseases such as sports injuries, but there are few studies of acupuncture treatment for skin diseases, including tinea pedis, in the field of military medicine. Herein, we report the case of a young Korean army member presenting with persistent pruritus diagnosed as tinea pedis. Case presentation","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"40 1","pages":"493 - 495"},"PeriodicalIF":2.5,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49589819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of treatment interventions for patellar tendinopathy: a secondary cost-effectiveness analysis","authors":"Daniel Fernández-Sanchis, M. López-Royo, C. Jiménez-Sánchez, P. Herrero, M. Gómez-Barrera, S. Calvo","doi":"10.1177/09645284221085283","DOIUrl":"https://doi.org/10.1177/09645284221085283","url":null,"abstract":"Objective: To compare the cost-effectiveness of three patellar tendinopathy treatments. Design: Secondary (cost-effectiveness) analysis of a blinded, randomised controlled trial, with follow-up at 10 and 22 weeks. Settings: Recruitment was performed in sport clubs. The diagnosis and the intervention were carried out at San Jorge University. Participants: The participants were adults between 18 and 45 years (n = 48) with patellar tendinopathy. Interventions: Participants received percutaneous needle electrolysis, dry needling or sham needling, all of which were combined with eccentric exercise. Main outcome measures: Costs, quality-adjusted life years and incremental cost-effectiveness ratio were calculated for each group. Results: The total cost per session was similar in the three groups: €9.46 for the percutaneous needle electrolysis group; €9.44 for the dry needling group; and €8.96 for the sham group. The percutaneous needle electrolysis group presented better cost-effectiveness in terms of quality-adjusted life years and 96% and 93% probability of being cost-effective compared to the sham and dry needling groups, respectively. Conclusion: Our study shows that percutaneous needle electrolysis has a greater probability of being cost-effective than sham or dry needling treatment.","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"40 1","pages":"516 - 523"},"PeriodicalIF":2.5,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45483313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early intervention of surrounding needling technique in the treatment of herpes zoster: a case report","authors":"Qingqing Xiao, P. Xiong, Zilei Tian, Yalan Liu, Qiao Wen, Lei Lan","doi":"10.1177/09645284221086287","DOIUrl":"https://doi.org/10.1177/09645284221086287","url":null,"abstract":"Herpes zoster is an infectious skin disease caused by the reactivation of varicella zoster virus that has long been latent in the posterior spinal or cranial ganglia.1 Early and effective intervention for herpes zoster is important for the prevention and treatment of post-herpetic neuralgia (PHN).2 The surrounding needling technique in acupuncture therapy, in which multiple needles are inserted around the lesion, has a long history in the treatment of herpes zoster, with evidence of efficacy.3 Here, we report a case of complete recovery of a patient with herpes zoster in whom the surrounding needling technique was applied at an early stage.","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"40 1","pages":"487 - 489"},"PeriodicalIF":2.5,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48538816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroacupuncture for cervicogenic dizziness with somatosensory pulsatile tinnitus.","authors":"Salaheddin Taleb Hessami Azar,&nbsp;Mike Cummings","doi":"10.1177/09645284221076514","DOIUrl":"https://doi.org/10.1177/09645284221076514","url":null,"abstract":"Cervicogenic dizziness (CGD) is a syndrome of dizziness and disequilibrium associated with neck pain.1 There are no definitive clinical or laboratory tests for CGD, and therefore, it must be a diagnosis of exclusion. Somatosensory pulsatile tinnitus (SSPT) is subgroup of tinnitus characterised by high-pitched, cardiac-synchronous tinnitus, in which pulsations are suppressed by strong contractions or compressions of the neck and jaw muscles (somatic testing).2 Electroacupuncture (EA) has been found to be effective in the treatment of chronic myofascial pain3,4; however, to our knowledge, it has not previously been reported in the treatment of CGD with SSPT.","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":"40 3","pages":"275-277"},"PeriodicalIF":2.5,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39643514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}