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Autophagy at the postsynapse begins with Rab11 and does not end with dendritic spine pruning 突触后的自噬始于 Rab11，并不随着树突棘的修剪而结束
Autophagy reports Pub Date : 2024-05-01 DOI: 10.1080/27694127.2024.2346064
Aleksandra Janusz-Kamińska, Jacek Jaworski
{"title":"Autophagy at the postsynapse begins with Rab11 and does not end with dendritic spine pruning","authors":"Aleksandra Janusz-Kamińska, Jacek Jaworski","doi":"10.1080/27694127.2024.2346064","DOIUrl":"https://doi.org/10.1080/27694127.2024.2346064","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"18 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141047718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combining doxorubicin and miR-218-5p: a new strategy to fight breast cancer? 多柔比星与 miR-218-5p：抗击乳腺癌的新策略？
Autophagy reports Pub Date : 2024-04-25 DOI: 10.1080/27694127.2024.2342129
F. D. Naso, F. Strappazzon
{"title":"Combining doxorubicin and miR-218-5p: a new strategy to fight breast cancer?","authors":"F. D. Naso, F. Strappazzon","doi":"10.1080/27694127.2024.2342129","DOIUrl":"https://doi.org/10.1080/27694127.2024.2342129","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"30 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140657653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous activation and blockade of autophagy to fight hepatocellular carcinoma 同时激活和阻断自噬以抗击肝细胞癌
Autophagy reports Pub Date : 2024-03-28 DOI: 10.1080/27694127.2024.2326241
Hala Shalhoub, Patrick Gonzalez, Alexandre Dos Santos, Julie Guillermet-Guibert, Nicolas Moniaux, Nicolas Dupont, J. Faivre
{"title":"Simultaneous activation and blockade of autophagy to fight hepatocellular carcinoma","authors":"Hala Shalhoub, Patrick Gonzalez, Alexandre Dos Santos, Julie Guillermet-Guibert, Nicolas Moniaux, Nicolas Dupont, J. Faivre","doi":"10.1080/27694127.2024.2326241","DOIUrl":"https://doi.org/10.1080/27694127.2024.2326241","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"27 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140372032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impaired autophagy flux contributes to enhanced ischemia reperfusion injury in the diabetic heart 自噬通量受损导致糖尿病心脏缺血再灌注损伤加重
Autophagy reports Pub Date : 2024-03-21 DOI: 10.1080/27694127.2024.2330327
Jialing Tang, Nanyoung Yoon, K. Dadson, Hye Kyoung Sung, Yubin Lei, Thanh Q. Dang, Wing Yan Chung, Saher Ahmed, A. Abdul-Sater, Jun Wu, Ren-Ke Li, James Jonkman, Trevor McKee, Justin Grant, Jeffrey D. Peterson, Gary Sweeney
{"title":"Impaired autophagy flux contributes to enhanced ischemia reperfusion injury in the diabetic heart","authors":"Jialing Tang, Nanyoung Yoon, K. Dadson, Hye Kyoung Sung, Yubin Lei, Thanh Q. Dang, Wing Yan Chung, Saher Ahmed, A. Abdul-Sater, Jun Wu, Ren-Ke Li, James Jonkman, Trevor McKee, Justin Grant, Jeffrey D. Peterson, Gary Sweeney","doi":"10.1080/27694127.2024.2330327","DOIUrl":"https://doi.org/10.1080/27694127.2024.2330327","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":" 65","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140221504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PINK1 regulated mitophagy is evident in skeletal muscles. PINK1 对有丝分裂的调控在骨骼肌中非常明显。
Autophagy reports Pub Date : 2024-03-11 DOI: 10.1080/27694127.2024.2326402
Francois Singh, Lea Wilhelm, Alan R Prescott, Kevin Ostacolo, Jin-Feng Zhao, Margret H Ogmundsdottir, Ian G Ganley
{"title":"PINK1 regulated mitophagy is evident in skeletal muscles.","authors":"Francois Singh, Lea Wilhelm, Alan R Prescott, Kevin Ostacolo, Jin-Feng Zhao, Margret H Ogmundsdottir, Ian G Ganley","doi":"10.1080/27694127.2024.2326402","DOIUrl":"10.1080/27694127.2024.2326402","url":null,"abstract":"<p><p>PINK1, mutated in familial forms of Parkinson's disease, initiates mitophagy following mitochondrial depolarization. However, it is difficult to monitor this pathway physiologically in mice as loss of PINK1 does not alter basal mitophagy levels in most tissues. To further characterize this pathway <i>in vivo</i>, we used <i>mito</i>-QC mice in which loss of PINK1 was combined with the mitochondrial-associated POLG<sup>D257A</sup> mutation. We focused on skeletal muscle as gene expression data indicates that this tissue has the highest PINK1 levels. We found that loss of PINK1 in oxidative hindlimb muscle significantly reduced mitophagy. Of interest, the presence of the POLG<sup>D257A</sup> mutation, while having a minor effect in most tissues, restored levels of muscle mitophagy caused by the loss of PINK1. Although our observations highlight that multiple mitophagy pathways operate within a single tissue, we identify skeletal muscle as a tissue of choice for the study of PINK1-dependant mitophagy under basal conditions.</p>","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"3 1","pages":"2326402"},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7616148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GRB2, a protein known for a long time with a new autophagy-regulating function GRB2，一种具有新的自噬调节功能的已知蛋白质
Autophagy reports Pub Date : 2024-03-06 DOI: 10.1080/27694127.2024.2325265
S. Vega-Rubín-de-Celis
{"title":"GRB2, a protein known for a long time with a new autophagy-regulating function","authors":"S. Vega-Rubín-de-Celis","doi":"10.1080/27694127.2024.2325265","DOIUrl":"https://doi.org/10.1080/27694127.2024.2325265","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140260936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alpha-synuclein aggregates trigger cardiolipin externalization and mitophagy α-突触核蛋白聚集体引发心磷脂外化和有丝分裂
Autophagy reports Pub Date : 2024-02-27 DOI: 10.1080/27694127.2024.2314361
Rebeca Martín-Jiménez, Olivier Lurette, Etienne Hebert-Chatelain
{"title":"Alpha-synuclein aggregates trigger cardiolipin externalization and mitophagy","authors":"Rebeca Martín-Jiménez, Olivier Lurette, Etienne Hebert-Chatelain","doi":"10.1080/27694127.2024.2314361","DOIUrl":"https://doi.org/10.1080/27694127.2024.2314361","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140426767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crosstalk between myocardial autophagy and sterile inflammation in the development of heart failure 心肌自噬与无菌性炎症在心力衰竭发病过程中的相互影响
Autophagy reports Pub Date : 2024-02-27 DOI: 10.1080/27694127.2024.2320605
Jialing Tang, Eddie Tam, Erfei Song, Aimin Xu, Gary Sweeney
{"title":"Crosstalk between myocardial autophagy and sterile inflammation in the development of heart failure","authors":"Jialing Tang, Eddie Tam, Erfei Song, Aimin Xu, Gary Sweeney","doi":"10.1080/27694127.2024.2320605","DOIUrl":"https://doi.org/10.1080/27694127.2024.2320605","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"29 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140425974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autophagy Determines Distinct Cell Fates in Human Amnion and Chorion Cells 自噬决定人类羊膜细胞和绒毛膜细胞的不同细胞命运
Autophagy reports Pub Date : 2024-02-07 DOI: 10.1080/27694127.2024.2306086
M. Severino, Lauren S. Richardson, A. Kammala, E. Radnaa, K. Khanipov, Leslie Michelle M. Dalmacio, Indira U. Mysorekar, Marian Kacerovsky, Ramkumar Menon
{"title":"Autophagy Determines Distinct Cell Fates in Human Amnion and Chorion Cells","authors":"M. Severino, Lauren S. Richardson, A. Kammala, E. Radnaa, K. Khanipov, Leslie Michelle M. Dalmacio, Indira U. Mysorekar, Marian Kacerovsky, Ramkumar Menon","doi":"10.1080/27694127.2024.2306086","DOIUrl":"https://doi.org/10.1080/27694127.2024.2306086","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139854555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autophagy Determines Distinct Cell Fates in Human Amnion and Chorion Cells 自噬决定人类羊膜细胞和绒毛膜细胞的不同细胞命运
Autophagy reports Pub Date : 2024-02-07 DOI: 10.1080/27694127.2024.2306086
M. Severino, Lauren S. Richardson, A. Kammala, E. Radnaa, K. Khanipov, Leslie Michelle M. Dalmacio, Indira U. Mysorekar, Marian Kacerovsky, Ramkumar Menon
{"title":"Autophagy Determines Distinct Cell Fates in Human Amnion and Chorion Cells","authors":"M. Severino, Lauren S. Richardson, A. Kammala, E. Radnaa, K. Khanipov, Leslie Michelle M. Dalmacio, Indira U. Mysorekar, Marian Kacerovsky, Ramkumar Menon","doi":"10.1080/27694127.2024.2306086","DOIUrl":"https://doi.org/10.1080/27694127.2024.2306086","url":null,"abstract":"","PeriodicalId":72341,"journal":{"name":"Autophagy reports","volume":"112 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139794741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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