Annals of hepato-biliary-pancreatic surgery最新文献

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Heterotopic pancreas of the gallbladder: A case report of a rare and commonly incidental finding. 胆囊异位胰腺:一个罕见的和通常偶然发现的病例报告。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-31 Epub Date: 2025-01-13 DOI: 10.14701/ahbps.24-190
Nelson Chen, Jessica Gu
{"title":"Heterotopic pancreas of the gallbladder: A case report of a rare and commonly incidental finding.","authors":"Nelson Chen, Jessica Gu","doi":"10.14701/ahbps.24-190","DOIUrl":"10.14701/ahbps.24-190","url":null,"abstract":"<p><p>Heterotopic pancreas (HP) refers to the presence of ectopic pancreatic tissue located outside of the normal pancreatic location without anatomical or vascular continuity with the pancreas. HP within the gallbladder (HPGB) was first described by Otschkin in 1916. It remains an exceedingly rare pathology with few reported cases. Here we describe a case of HPGB in a 42-year-old female following laparoscopic cholecystectomy for symptoms of biliary colic. She presented with epigastric pain, elevated levels in liver function tests, and gallbladder sludge on ultrasound. Her lipase and bilirubin levels were within normal limits. Histopathological assessment of the gallbladder identified mild chronic cholecystitis and pancreatic heterotopia adjacent to the cystic duct of the gallbladder with all three elements (ducts, acini, and endocrine islets) of the pancreas, consistent with type 1 based on the classification of Gaspar Fuentes et al. HPGB is often diagnosed incidentally during histopathological examination after cholecystectomy. Preoperative diagnosis is challenging due to its rarity. It is thought to be asymptomatic. Although the clinical significance of HPGB remains uncertain, it has been hypothesized that HPGB can cause acalculous cholecystitis and also have the potential for malignant transformation. Our case supports the theory that the exocrine function of an ectopic pancreatic tissue may contribute to chronic inflammation in the gallbladder. In conclusion, although HPGB is a rare finding with unclear clinical relevance, its potential for malignancy and association with cholecystitis warrant further investigation. Given its scarcity, most knowledge about HPGB comes from case reports and case series. This report adds to the existing literature.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"205-208"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome after spleen-preserving distal pancreatectomy by Warshaw technique for pancreatic body cancer. Warshaw技术保脾胰远端切除术治疗胰小体癌的疗效观察。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-31 Epub Date: 2025-03-24 DOI: 10.14701/ahbps.24-202
Endi Zhou, Guodong Shi, Hongyuan Shi, Kai Zhang, Jishu Wei, Min Tu, Zipeng Lu, Feng Guo, Jianmin Chen, Kuirong Jiang, Wentao Gao
{"title":"Outcome after spleen-preserving distal pancreatectomy by Warshaw technique for pancreatic body cancer.","authors":"Endi Zhou, Guodong Shi, Hongyuan Shi, Kai Zhang, Jishu Wei, Min Tu, Zipeng Lu, Feng Guo, Jianmin Chen, Kuirong Jiang, Wentao Gao","doi":"10.14701/ahbps.24-202","DOIUrl":"10.14701/ahbps.24-202","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Distal pancreatectomy with splenectomy (DPS) is a common surgical procedure for pancreatic body cancer. However, spleen-preserving distal pancreatectomy (SPDP) utilizing the Warshaw technique (WT) in malignancies is generally not favored due to concerns about inadequate resection. This study aims to assess the feasibility and oncologic outcomes of employing SPDP with WT in pancreatic body cancer.</p><p><strong>Methods: </strong>We conducted a retrospective analysis comparing 21 SPDP patients with 63 DPS patients matched by propensity score from January 2018 to November 2022. Clinical outcomes and follow-up data were analyzed using R.</p><p><strong>Results: </strong>Both groups exhibited similar demographic, intraoperative, and pathological characteristics, with the exception of a reduced number of total lymph nodes (<i>p</i> = 0.006) in the SPDP group. There were no significant differences in the rates of postoperative complications, recurrence, or metastasis. Local recurrence predominantly occurred in the central region as opposed to the spleen region. There were no cases of isolated recurrences in the splenic region. Median overall survival and recurrence-free survival times were 51.5 months for SPDP vs 30.5 months for DPS and 18.7 months vs 16.8 months, respectively (<i>p</i> > 0.05). The incidence of partial splenic infarction and left-side portal hypertension in the SPDP group was 28.6% (6/21) and 9.5% (2/21), respectively, without necessitating splenic abscess puncture, splenectomy, or causing bleeding from perigastric varices.</p><p><strong>Conclusions: </strong>SPDP did not negatively impact local recurrence or survival rates in selected pancreatic body cancer patients. Further studies are necessary for validation.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"177-186"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is it time to define the scope of safety for robotic resection in perihilar cholangiocarcinoma surgery? A propensity score matching based analysis of a single center experience. 在肝门周围胆管癌手术中,是时候确定机器人切除的安全范围了吗?基于单中心经验的倾向评分匹配分析。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-31 Epub Date: 2025-04-15 DOI: 10.14701/ahbps.25-012
Mikhail Efanov, Pavel Tarakanov, Yuliya Kulezneva, Olga Melekhina, Anna Koroleva, Andrey Vankovich, Dmitry Kovalenko, Denis Fisenko, Victor Tsvirkun, Igor Khatkov
{"title":"Is it time to define the scope of safety for robotic resection in perihilar cholangiocarcinoma surgery? A propensity score matching based analysis of a single center experience.","authors":"Mikhail Efanov, Pavel Tarakanov, Yuliya Kulezneva, Olga Melekhina, Anna Koroleva, Andrey Vankovich, Dmitry Kovalenko, Denis Fisenko, Victor Tsvirkun, Igor Khatkov","doi":"10.14701/ahbps.25-012","DOIUrl":"10.14701/ahbps.25-012","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Robotic surgery for perihilar cholangiocarcinoma is in the developmental and exploratory phase. The objective of this study was to compare the short-term outcomes and survival rates of robotic versus open resection for perihilar cholangiocarcinoma in a single center, and to determine the reliable scope of robotic interventions.</p><p><strong>Methods: </strong>A comparative analysis of outcomes from open and robotic resections at a single center was conducted using propensity score matching (PSM). The balance of covariates was assessed using standardized mean differences, and the robotic resection procedures adhered to the standards of open surgery.</p><p><strong>Results: </strong>PSM was effectively applied between 41 robotic and 82 open resections. No differences were observed in blood loss, overall and severe morbidity, 90-day mortality, or length of hospital stay. Robotic resections were longer but resulted in better immediate oncological outcomes. Median overall survival for the robotic and open groups was 44 and 30 months (<i>p</i> = 0.259) before PSM and 44 and 29 months (<i>p</i> = 0.164) after PSM respectively. Conversion was required in 8 cases. A subgroup analysis excluding conversions revealed no differences in immediate and long-term outcomes. All patients undergoing robotic resection for Bismuth types I and II were alive at a mean follow-up of 37 months.</p><p><strong>Conclusions: </strong>The robotic approach is comparable to open resection regarding immediate outcomes and survival in select patients with perihilar cholangiocarcinoma. For patients with Bismuth type I and II tumors and early (stages I and II) TNM stages, robotic resection is a reliable treatment option when aligned with the principles of open surgery.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":"29 2","pages":"127-139"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility and safety of robotic radical resection for hilar cholangiocarcinoma in highly selected patients: A systematic review and meta-analysis with meta-regression. 机器人根治术治疗高选择性患者肝门胆管癌的可行性和安全性:一项系统综述和荟萃分析。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-31 Epub Date: 2025-02-26 DOI: 10.14701/ahbps.24-236
Shahab Hajibandeh, Shahin Hajibandeh, Thomas Satyadas
{"title":"Feasibility and safety of robotic radical resection for hilar cholangiocarcinoma in highly selected patients: A systematic review and meta-analysis with meta-regression.","authors":"Shahab Hajibandeh, Shahin Hajibandeh, Thomas Satyadas","doi":"10.14701/ahbps.24-236","DOIUrl":"10.14701/ahbps.24-236","url":null,"abstract":"<p><p>To examine the feasibility and safety of robotic radical resection (RRR) for hilar cholangiocarcinoma (HCCA). A PRISMA-compliant meta-analysis with meta-regression was conducted, including studies reporting outcomes of RRR in patients with HCCA. Six studies comprising 295 patients were included. In highly selected patients (body mass index [BMI] < 25 kg/m\" ; tumor size < 3 cm), RRR of HCCA proved safe and feasible (Clavien-Dindo ≥ III complications: 14.8% [95% confidence interval 8.7%-20.8%]; 30-day mortality: 1.9% [0%-4.2%]; conversion to open surgery: 1.9% [0%-4.2%]; intraoperative blood loss: 210 mL [119-301 mL]; operative time: 481 minutes [339-623 minutes]; R0 resection rate: 82.2% [75.0%-89.4%]; retrieved lymph nodes: 12 [9-16]). Younger age (<i>p</i> = 0.008), higher BMI (<i>p</i> = 0.009), larger tumors (<i>p</i> = 0.048), and performing liver resections (<i>p</i> = 0.017) increased blood loss. American Society of Anesthesiologists status ≥ III (<i>p</i> < 0.001) and Bismuth IV disease (<i>p</i> < 0.001) increased operative times. Preoperative biliary drainage (<i>p</i> = 0.027) enhanced R0 resection rates. RRR led to less bleeding (mean difference [MD]: -184 mL, <i>p</i> = 0.0005), longer operative times (MD: 162 minutes, <i>p</i> = 0.001), and improved R0 resection rates (odds ratio: 3.29, <i>p</i> = 0.006) compared with the open approach. Subject to selection bias and type 2 error, RRR for HCCA might be safe and feasible in highly selected patients (favorable BMI and tumor size). The findings should not be taken as definitive conclusions but may be used for hypothesis generation in subsequent trials.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"99-112"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143505990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From the operating room: Surgeons' views on difficult laparoscopic cholecystectomies. 从手术室看:外科医生对腹腔镜胆囊切除术难度的看法。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-31 Epub Date: 2025-02-26 DOI: 10.14701/ahbps.24-219
Ritika Agarwal, Vinay M D Prabhu, Nitin A R Rao
{"title":"From the operating room: Surgeons' views on difficult laparoscopic cholecystectomies.","authors":"Ritika Agarwal, Vinay M D Prabhu, Nitin A R Rao","doi":"10.14701/ahbps.24-219","DOIUrl":"10.14701/ahbps.24-219","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Assessing surgical difficulty in laparoscopic cholecystectomy (LC) is challenging due to variations in surgeon proficiency and institutional protocols. This study evaluates surgeons' perspectives on procedural difficulty and examines how intraoperative findings and preoperative imaging contribute to refining difficulty assessment criteria.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted among 50 laparoscopic surgeons in India, providing insights into tolerances for surgical duration and blood loss, reasons for conversion, and predictors of complexity. Responses were analyzed using SPSS, with statistical significance set at <i>p</i> < 0.05.</p><p><strong>Results: </strong>Among surveyed surgeons, 82.0% were male, and 78.0% worked in private institutions and 52.0% had performed over 1,000 LCs. Conversion to open surgery was primarily influenced by significant blood loss (68.0%) and biliary injury (94.0%). While 38.0% preferred surgeries under 60 minutes, 26.0% imposed no time constraints. Key intraoperative challenges included dense adhesions, cholecysto-enteric fistulas, and fibrosis. Less experienced surgeons reported greater challenges with scarring adhesions and anatomical variations, but no significant differences were found for other factors like edematous or necrotic changes. Preoperative imaging was considered essential by most surgeons.</p><p><strong>Conclusions: </strong>This study underscores the limited reliability of traditional parameters for assessing difficulty in LC. Surgeons highlighted the importance of objective intraoperative findings and preoperative imaging in predicting surgical challenges. Factors such as adhesions, fibrosis, and anatomical variations significantly impact LC difficulty, with decisions regarding conversion to open surgery largely driven by individual judgment rather than experience. Standardized grading systems incorporating these factors could improve surgical planning, reduce complications, and enhance patient outcomes.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"150-156"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of intraoperative choledochoscopy in laparoscopic subtotal cholecystectomy for severe cholecystitis. 术中胆道镜在重度胆囊炎腹腔镜胆囊次全切除术中的应用。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-31 Epub Date: 2025-04-16 DOI: 10.14701/ahbps.25-010
Rui-Hui Zhang, Xiang-Nan Wang, Yue-Feng Ma, Xue-Qian Tang, Mei-Ju Lin, Li-Jun Shi, Jing-Yi Li, Hong-Wei Zhang
{"title":"Usefulness of intraoperative choledochoscopy in laparoscopic subtotal cholecystectomy for severe cholecystitis.","authors":"Rui-Hui Zhang, Xiang-Nan Wang, Yue-Feng Ma, Xue-Qian Tang, Mei-Ju Lin, Li-Jun Shi, Jing-Yi Li, Hong-Wei Zhang","doi":"10.14701/ahbps.25-010","DOIUrl":"10.14701/ahbps.25-010","url":null,"abstract":"<p><p>Laparoscopic subtotal cholecystectomy (LSC) has been a safe and viable alternative to conversion to laparotomy in cases of severe cholecystitis. The objective of this study is to determine the utility of intraoperative choledochoscopy in LSC for the exploration of the gallbladder, cyst duct, and subsequent stone clearance of the cystic duct in cases of severe cholecystitis. A total of 72 patients diagnosed with severe cholecystitis received choledochoscopy-assisted laparoscopic subtotal cholecystectomy (CALSC). A choledochoscopy was performed to explore the gallbladder cavity and/or cystic duct, and to extract stones using a range of techniques. The clinical records, including the operative records and outcomes, were subjected to analysis. No LSC was converted to open surgery, and no bile duct or vascular injuries were sustained. All stones within the cystic duct were removed by a combination of techniques, including high-frequency needle knife electrotomy, basket, and electrohydraulic lithotripsy. A follow-up examination revealed the absence of residual bile duct stones, with the exception of one common bile duct stone, which was extracted via endoscopic retrograde cholangiopancreatography. In certain special cases, CALSC may prove to be an efficacious treatment for the management of severe cholecystitis. This technique allows for optimal comprehension of the situation within the gallbladder cavity and cystic duct, facilitating the removal of stones from the cystic duct and reducing the residue of the non-functional gallbladder remnant.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":"29 2","pages":"192-198"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comprehensive study on postoperative complications and postoperative pancreatic fistula in sporadic non-functional pancreatic neuroendocrine tumors: A retrospective cohort study. 散发性无功能胰腺神经内分泌肿瘤术后并发症及胰瘘的综合研究:回顾性队列研究。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-31 Epub Date: 2025-02-13 DOI: 10.14701/ahbps.24-215
Juwan Kim, Seung Soo Hong, Sung Hyun Kim, Ho Kyoung Hwang, Chang Moo Kang
{"title":"A comprehensive study on postoperative complications and postoperative pancreatic fistula in sporadic non-functional pancreatic neuroendocrine tumors: A retrospective cohort study.","authors":"Juwan Kim, Seung Soo Hong, Sung Hyun Kim, Ho Kyoung Hwang, Chang Moo Kang","doi":"10.14701/ahbps.24-215","DOIUrl":"10.14701/ahbps.24-215","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Balancing surgical risks and benefits is crucial for managing non-functional pancreatic neuroendocrine tumors (NF-PNETs). Despite high postoperative pancreatic fistula (POPF) rates, studies on postoperative complications of sporadic NF-PNETs are scarce. Thus, this study aimed to investigate postoperative complications and identify risk factors for POPF.</p><p><strong>Methods: </strong>A retrospective review of 166 NF-PNET surgeries performed at Severance Hospital between February 2000 and August 2023 was conducted.</p><p><strong>Results: </strong>Age > 65 years and higher American Society of Anesthesiology (ASA) grade were not significantly correlated with severe complications (odds ratio [OR]: 1.10, <i>p</i> = 0.871 and OR: 1.47, <i>p</i> = 0.491, respectively). Surgical procedures included enucleation (13.9%), distal pancreatectomy (50.0%), central pancreatectomy (4.8%), pancreaticoduodenectomy (PD) (26.5%), and total pancreatectomy (4.8%). Severe complications occurred in 12.05% of surgeries. The overall incidence of all POPFs including biochemical leaks was 53%, while clinically relevant POPF (grade B or C) occurred in 7.8% of patients. Logistic regression showed that PD (OR: 3.94, <i>p</i> = 0.092) tended to be risk factor for POPF and that diameter of the main pancreatic duct (MPD) ≤ 3 mm was a significant risk factor for POPF (OR: 0.22, <i>p</i> = 0.008). A pancreas thickness (PT)/MPD ratio > 4.47 on preoperative computed tomography predicted all POPFs in PD patients (OR: 11.70, <i>p</i> = 0.001).</p><p><strong>Conclusions: </strong>Age and comorbidities had no significant impact on surgical outcomes. PD was associated with higher serious complications and POPF rates. The PT/MPD ratio is a valuable preoperative tool for predicting POPF risk in PD patients.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"168-176"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term and long-term outcomes of pancreas preserving total duodenectomy: A case series from a single center with 13 years' experience and complimentary meta-analysis. 保留胰腺的全十二指肠切除术的短期和长期结果:来自具有13年经验的单一中心的病例系列和补充荟萃分析。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-31 Epub Date: 2025-02-20 DOI: 10.14701/ahbps.24-214
Mohammed Hammoda, Shahab Hajibandeh, Bilal Al-Sarireh
{"title":"Short-term and long-term outcomes of pancreas preserving total duodenectomy: A case series from a single center with 13 years' experience and complimentary meta-analysis.","authors":"Mohammed Hammoda, Shahab Hajibandeh, Bilal Al-Sarireh","doi":"10.14701/ahbps.24-214","DOIUrl":"10.14701/ahbps.24-214","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>To determine short-term and long-term outcomes after pancreas preserving total duodenectomy (PPTD).</p><p><strong>Methods: </strong>A case series and a complementary meta-analysis were conducted. All patients with (pre)neoplastic lesions of duodenum who underwent PPTD in a tertiary center for pancreatic surgery between May 2009 and October 2022 were included for the case series. All studies in the literature with a sample size of 10 or more patients reporting outcomes of PPTD were included for the meta-analysis.</p><p><strong>Results: </strong>A total of 439 patients (18 from case series and 421 from literature) were analyzed. Clavien-Dindo (CD) I complications in 2.9% (95% confidence interval [CI] 0.6%-5.2%), CD II complications in 21.1% (14.6%-27.6%), CD III complications in 18.1% (9.3%-26.9%), CD IV complications in 2.7% (0.5%-4.9%), and CD V complications in 2.2% (0.2%-4.2%) of patients were found. Probabilities of overall survival and recurrence-free survival at 15 years were 87% and 86%, respectively. There was no significant difference in the risk of mortality (odds ratio [OR]: 0.82, <i>p</i> = 0.830), total complications (OR: 0.77, <i>p</i> = 0.440), postoperative pancreatic fistula (OR: 0.43, <i>p</i> = 0.140), delayed gastric emptying (OR: 0.70, <i>p</i> = 0.450), or postoperative bleeding (OR: 0.97, <i>p</i> = 0.960) between PPTD and pancreaticoduodenectomy.</p><p><strong>Conclusions: </strong>PPTD is safe and feasible for (pre)neoplastic lesions of duodenum not involving the pancreatic head. The risk of severe complications (CD > III) is low and long-term outcomes are favorable. Whether PPTD provides advantages over more radical techniques in terms of long-term outcomes remains controversial and requires further research.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"157-167"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term outcomes of pancreato-duodenectomy for groove pancreatitis: A retrospective experience from a tertiary referral center. 胰十二指肠切除术治疗沟状胰腺炎的长期结果:来自三级转诊中心的回顾性经验。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-26 DOI: 10.14701/ahbps.25-041
Zeeshan Ahmed, Raviraj Tilloo, Monish Karunakaran, Shreeyash Modak, Prateek Arora, Sanjeev Patil, Anuradha Sekaran, Mohan Ramchandani, Mahesh Shetty, Rohit Dama, Pradeep Rebala, Guduru Venkat Rao
{"title":"Long-term outcomes of pancreato-duodenectomy for groove pancreatitis: A retrospective experience from a tertiary referral center.","authors":"Zeeshan Ahmed, Raviraj Tilloo, Monish Karunakaran, Shreeyash Modak, Prateek Arora, Sanjeev Patil, Anuradha Sekaran, Mohan Ramchandani, Mahesh Shetty, Rohit Dama, Pradeep Rebala, Guduru Venkat Rao","doi":"10.14701/ahbps.25-041","DOIUrl":"https://doi.org/10.14701/ahbps.25-041","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Groove pancreatitis (GP) is a seldom encountered form of chronic pancreatitis characterized by inflammation of the pancreatoduodenal groove. Our study presents our experience with pancreatoduodenectomy (PD) for GP at a tertiary referral center.</p><p><strong>Methods: </strong>We conducted a retrospective review of patients who underwent PD for a preoperative diagnosis of GP at a tertiary referral center from 2010 to 2024. The primary outcomes were long-term pain relief and risks of recurrent pancreatitis, exocrine, and endocrine insufficiency. Secondary outcomes included perioperative complications.</p><p><strong>Results: </strong>During the study period, 19 patients underwent PD for GP. The median age was 45.5 years, and all patients were male. Eighty percent of the patients had a history of alcohol consumption and smoking. The median duration of symptoms was 24 months, with pain being the most prevalent symptom (94.73%). The overall complication rate (Clavien-Dindo grades 1-5) was 52.63% (10/19), and the major complication rate (Clavien-Dindo grades 3-5) was 21.05%. The median follow-up period was 67.25 months. Complete pain relief was achieved in 73.33% (11/15) of the patients, with the remaining 26.66% (4/15) experiencing partial resolution of pain. Among these, all had recurrent pancreatitis in the remnant pancreas, with ongoing alcohol consumption (n = 3) or smoking (n = 4). New-onset diabetes mellitus and steatorrhea were observed in 42.85% (6/14) and 21.42% (3/14) of patients, respectively. Furthermore, 71.42% (10/14) reported weight gain, with a median increase of 13.5 kg (range 5.00-22.75 kg).</p><p><strong>Conclusions: </strong>PD for GP offers substantial long-term pain relief with acceptable levels of perioperative morbidity and mortality.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges and outcomes of pancreato-duodenectomy in portal annular pancreas: A single center experience with a systematic review of the literature. 胰十二指肠切除术治疗门静脉环形胰腺的挑战和结果:单中心经验和文献系统回顾。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2025-05-23 DOI: 10.14701/ahbps.25-027
Shreeyash Modak, Raviraj Tilloo, Zeeshan Ahmed, Monish Karunakaran, Sanjeev Patil, Mahesh Shetty, Rohit Dama, Pradeep Rebala, Guduru Venkat Rao
{"title":"Challenges and outcomes of pancreato-duodenectomy in portal annular pancreas: A single center experience with a systematic review of the literature.","authors":"Shreeyash Modak, Raviraj Tilloo, Zeeshan Ahmed, Monish Karunakaran, Sanjeev Patil, Mahesh Shetty, Rohit Dama, Pradeep Rebala, Guduru Venkat Rao","doi":"10.14701/ahbps.25-027","DOIUrl":"https://doi.org/10.14701/ahbps.25-027","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Portal annular pancreas (PAP) is an anomaly where pancreatic tissue surrounds the portal vein (PV). We present a case series from our institution and a systematic review of PAP patients who underwent pancreatoduodenectomy (PD).</p><p><strong>Methods: </strong>We conducted a retrospective review of patient records from a tertiary referral center, from January 2014 to June 2024, who underwent PD to identify those with PAP. Additionally, a literature search was performed and articles discussing PAP patients who underwent PD were included.</p><p><strong>Results: </strong>The incidence of PAP was 0.4% (7 out of 1,750 PD cases). Of these, three (42.85%) patients developed clinically relevant postoperative pancreatic fistula (CR-POPF). Following the literature review, 34 articles with 57 patients (including our study) were considered. Reconstruction of the dominant stump, which included the main pancreatic duct, was performed using pancreatojejunostomy in 88.88% of cases and pancreatogastrostomy in 11.11% of cases. The non-dominant stump was managed with en-bloc extended resection (ER) of PAP, leftward of the PV, offering a single-cut surface for pancreatojejunostomy (41.51%), by stapling (26.41%) or suturing the stump (16.98%), stump-pancreatogastrostomy (5.66%), and electrocautery (5.66%). CR-POPF rates for ER, suturing and stapling were 22.72%, 37.5%, and 53.85%, respectively (<i>p</i> = 0.12).</p><p><strong>Conclusions: </strong>Preoperative recognition of PAP is crucial to customize surgical procedures to effectively manage the non-dominant stump.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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