Annals of hepato-biliary-pancreatic surgery最新文献

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Three-dimensional printing of intra-abdominal cavity to prevent large-for-size syndrome in liver transplantation: Correspondence. 三维打印腹腔以防止肝移植中的大尺寸综合征:通讯。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-11-05 DOI: 10.14701/ahbps.24-188
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"Three-dimensional printing of intra-abdominal cavity to prevent large-for-size syndrome in liver transplantation: Correspondence.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.14701/ahbps.24-188","DOIUrl":"https://doi.org/10.14701/ahbps.24-188","url":null,"abstract":"","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare case of a large solid pseudopapillary neoplasm with extensive liver metastasis. 一例罕见的巨大实性假乳头状瘤伴广泛肝转移。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-10-15 DOI: 10.14701/ahbps.24-147
Jun Hyung Kim, Hyung Sun Kim, Jung Min Lee, Ji Hae Nahm, Joon Seong Park
{"title":"A rare case of a large solid pseudopapillary neoplasm with extensive liver metastasis.","authors":"Jun Hyung Kim, Hyung Sun Kim, Jung Min Lee, Ji Hae Nahm, Joon Seong Park","doi":"10.14701/ahbps.24-147","DOIUrl":"https://doi.org/10.14701/ahbps.24-147","url":null,"abstract":"<p><p>Solid pseudopapillary neoplasms (SPNs) are uncommon pancreatic tumors that primarily affect young females. We report a case of a 24-year-old female diagnosed with SPN and liver metastasis during a routine examination. Imaging revealed an 8-cm pancreatic mass with multiple liver metastases. Histopathology confirmed SPN. Subsequent next-generation sequencing revealed a <i>CTNNB1</i> mutation. The patient underwent a total pancreatectomy with splenectomy, right hemihepatectomy, and intraoperative radiofrequency ablation. Two years after the surgery, she remained complication-free. She is under regular surveillance. This case underscores the importance of early detection and comprehensive management of SPN.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved graft survival by using three-dimensional printing of intra-abdominal cavity to prevent large-for-size syndrome in liver transplantation. 利用腹腔内三维打印技术提高移植物存活率,防止肝移植中的大尺寸综合征。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-09-26 DOI: 10.14701/ahbps.24-153
Sunghae Park, Gyu-Seong Choi, Jong Man Kim, Sanghoon Lee, Jae-Won Joh, Jinsoo Rhu
{"title":"Improved graft survival by using three-dimensional printing of intra-abdominal cavity to prevent large-for-size syndrome in liver transplantation.","authors":"Sunghae Park, Gyu-Seong Choi, Jong Man Kim, Sanghoon Lee, Jae-Won Joh, Jinsoo Rhu","doi":"10.14701/ahbps.24-153","DOIUrl":"https://doi.org/10.14701/ahbps.24-153","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>While large-for-size syndrome is uncommon in liver transplantation (LT), it can result in fatal outcome. To prevent such fatality, we manufactured 3D-printed intra-abdominal cavity replicas to provide intuitive understanding of the sizes of the graft and the patient's abdomen in patients with small body size between July 2020 and February 2022.</p><p><strong>Methods: </strong>Clinical outcomes were compared between patients using our 3D model during LT, and patients who underwent LT without 3D model by using 1 : 5 ratio propensity score-matched analysis.</p><p><strong>Results: </strong>After matching, a total of 20 patients using 3D-printed abdominal cavity model and 100 patients of the control group were included in this study. There were no significant differences in 30-day postoperative complication (50.0% vs. 64.0%, <i>p</i> = 0.356) and the incidence of large-for-size syndrome (0% vs. 7%, <i>p</i> = 0.599). Overall survival of the 3D-printed group was similar to that of the control group (<i>p</i> = 0.665), but graft survival was significantly superior in the 3D-printed group, compared to the control group (<i>p</i> = 0.034).</p><p><strong>Conclusions: </strong>Since it showed better graft survival, as well as low cost and short production time, our 3D-printing protocol can be a feasible option for patients with small abdominal cavity to prevent large-for-size syndrome after LT.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally invasive pancreatoduodenectomy with combined venous vascular resection: A comparative analysis with open approach. 结合静脉血管切除术的微创胰十二指肠切除术:与开放式方法的比较分析
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-09-24 DOI: 10.14701/ahbps.24-082
Dong Hyun Shin, Munseok Choi, Seoung Yoon Rho, Seung Soo Hong, Sung Hyun Kim, Ho Kyoung Hwang, Chang Moo Kang
{"title":"Minimally invasive pancreatoduodenectomy with combined venous vascular resection: A comparative analysis with open approach.","authors":"Dong Hyun Shin, Munseok Choi, Seoung Yoon Rho, Seung Soo Hong, Sung Hyun Kim, Ho Kyoung Hwang, Chang Moo Kang","doi":"10.14701/ahbps.24-082","DOIUrl":"https://doi.org/10.14701/ahbps.24-082","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>This study aimed to compare the minimally invasive pancreatoduodenectomy with venous vascular resection (MI-PDVR) and open pancreatoduodenectomy with venous vascular resection (O-PDVR) for periampullary cancer.</p><p><strong>Methods: </strong>Data of 124 patients who underwent PDVR (45 MI-PDVR, 79 O-PDVR) between January 1, 2016, and December 31, 2023, was retrospectively reviewed.</p><p><strong>Results: </strong>MI-PDVR is significantly better than O-PDVR in terms of perioperative outcomes (median operation time [452.69 minutes vs. 543.91 minutes; <i>p</i> = 0.004], estimated blood loss [410.44 mL vs. 747.59 mL; <i>p</i> < 0.01], intraoperative transfusion rate [2 cases vs. 18 cases; <i>p</i> = 0.01], and hospital stay [18.16 days vs. 23.91 days; <i>p</i> = 0.008]). The complications until the discharge day showed no significant difference between the two groups (Clavien-Dindo < 3, 84.4% vs. 82.3%; Clavien-Dindo ≥ 3, 15.6% vs. 17.7%; <i>p</i> = 0.809). In terms of long-term oncological outcomes, there was no statistical difference in overall survival (OS, 51.55 months [95% CI: 35.95-67.14] vs. median 49.92 months [95% CI: 40.97-58.87]; <i>p</i> = 0.340) and disease-free survival (DFS, median 35.06 months [95% CI: 21.47-48.65] vs. median 38.77 months [95% CI: 29.80-47.75]; <i>p</i> = 0.585), between the two groups. Long-term oncological outcomes for subgroup analysis focusing on pancreatic ductal adenocarcinoma also showed no statistical differences in OS (40.86 months [95% CI: 34.45-47.27] vs. 48.48 months [95% CI: 38.16-58.59]; <i>p</i> = 0.270) and DFS (24.42 months [95% CI: 17.03-31.85] vs. 34.35 months, [95% CI: 25.44-43.27]; <i>p</i> = 0.740).</p><p><strong>Conclusions: </strong>MI-PDVR can provide better perioperative outcomes than O-PDVR, and has similar oncological impact.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative outcomes of robot-assisted pancreatoduodenectomy (PD) and totally laparoscopic PD after overcoming learning curves with comparison of oncologic outcomes between open PD and minimally invasive PD. 克服学习曲线后机器人辅助胰十二指肠切除术(PD)和全腹腔镜胰十二指肠切除术的围手术期疗效,以及开放式胰十二指肠切除术和微创胰十二指肠切除术的肿瘤学疗效比较。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-09-24 DOI: 10.14701/ahbps.24-121
Jae Seung Kang, Mirang Lee, Jun Suh Lee, Youngmin Han, Hee Ju Sohn, Boram Lee, Moonhwan Kim, Wooil Kwon, Ho-Seong Han, Yoo-Seok Yoon, Jin-Young Jang
{"title":"Perioperative outcomes of robot-assisted pancreatoduodenectomy (PD) and totally laparoscopic PD after overcoming learning curves with comparison of oncologic outcomes between open PD and minimally invasive PD.","authors":"Jae Seung Kang, Mirang Lee, Jun Suh Lee, Youngmin Han, Hee Ju Sohn, Boram Lee, Moonhwan Kim, Wooil Kwon, Ho-Seong Han, Yoo-Seok Yoon, Jin-Young Jang","doi":"10.14701/ahbps.24-121","DOIUrl":"https://doi.org/10.14701/ahbps.24-121","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Minimally invasive pancreatoduodenectomy (MIPD), such as totally laparoscopic pancreatoduodenectomy (TLPD) or robot-assisted pancreatoduodenectomy (RAPD), is increasingly performed worldwide. This study aimed to compare the perioperative outcomes of TLPD and RAPD, and compare the oncologic outcomes between MIPD and open pancreatoduodenectomy (OPD) for malignant disease.</p><p><strong>Methods: </strong>This retrospective study was conducted at two hospitals that followed similar oncological surgical principles, including the extent of resection. RAPD was performed at Seoul National University Hospital, and TLPD at Seoul National University Bundang Hospital. Patient demographics, perioperative outcomes, and oncological outcomes were analyzed. Propensity score matching (PSM) analysis was performed to compare oncologic outcomes between MIPD and OPD.</p><p><strong>Results: </strong>Between 2015 and 2020, 332 RAPD and 178 TLPD were performed. The rates of Clavian-Dindo grade ≥ 3 complications (19.3% vs. 20.2%, <i>p</i> = 0.816), clinically relevant postoperative pancreatic fistula (9.9% vs. 11.8%, <i>p</i> = 0.647), and open conversions (6.6% vs. 10.5%, <i>p</i> = 0.163) were comparable between the two groups. The mean operation time (341 minutes vs. 414 minutes, <i>p</i> < 0.001) and postoperative hospital stay were shorter in the RAPD group (11 days vs. 14 days, <i>p</i> = 0.034). After PSM, the 5-year overall survival rate was comparable between MIPD and OPD for overall malignant disease (58.4% vs. 55.5%, <i>p</i> = 0.180).</p><p><strong>Conclusions: </strong>Both RAPD and TLPD are safe and feasible, and MIPD has clinical outcomes that are comparable to those of OPD. Although RAPD exhibits some advantages, its perioperative outcomes are similar to those associated with TLPD. A surgical method may be selected based on the convenience of surgical movements, medical costs, and operator experience.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ArtiSential® laparoscopic cholecystectomy versus single-fulcrum laparoscopic cholecystectomy: Which minimally invasive surgery is better? ArtiSential® 腹腔镜胆囊切除术与单全腔腹腔镜胆囊切除术:哪种微创手术更好?
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-09-24 DOI: 10.14701/ahbps.24-137
Jae Hwan Jeong, Seung Soo Hong, Munseok Choi, Seoung Yoon Rho, Pejman Radkani, Brian Kim Poh Goh, Yuichi Nagakawa, Minoru Tanabe, Daisuke Asano, Chang Moo Kang
{"title":"ArtiSential<sup>®</sup> laparoscopic cholecystectomy versus single-fulcrum laparoscopic cholecystectomy: Which minimally invasive surgery is better?","authors":"Jae Hwan Jeong, Seung Soo Hong, Munseok Choi, Seoung Yoon Rho, Pejman Radkani, Brian Kim Poh Goh, Yuichi Nagakawa, Minoru Tanabe, Daisuke Asano, Chang Moo Kang","doi":"10.14701/ahbps.24-137","DOIUrl":"https://doi.org/10.14701/ahbps.24-137","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>In recent years, many minimally invasive techniques have been introduced to reduce the number of ports in laparoscopic cholecystectomy (LC), offering benefits such as reduced postoperative pain and improved cosmetic outcomes. ArtiSential<sup>®</sup> is a new multi-degree-of-freedom articulating laparoscopic instrument that incorporates the ergonomic features of robotic surgery, potentially overcoming the spatial limitations of laparoscopic surgery. ArtiSential<sup>®</sup> LC can be performed using only two ports. This study aims to compare the surgical outcomes of ArtiSential<sup>®</sup> LC with those of single-fulcrum LC.</p><p><strong>Methods: </strong>This retrospective study compared ArtiSential<sup>®</sup> LC and single-fulcrum LC among LCs performed for gallbladder (GB) stones at the same center, analyzing the basic characteristics of patients; intraoperative outcomes, such as operative time, estimated blood loss, and intraoperative GB rupture; and postoperative outcomes, such as length of hospital stay, incidence of postoperative complications, and postoperative pain.</p><p><strong>Results: </strong>A total of 88 and 63 patients underwent ArtiSential<sup>®</sup> LC and single-fulcrum LC for GB stones, respectively. Analysis showed that ArtiSential<sup>®</sup> LC resulted in significantly fewer cases of surgeries longer than 60 minutes (30 vs. 35 min, <i>p</i> = 0.009) and intraoperative GB ruptures (2 vs. 10, <i>p</i> = 0.007). In terms of postoperative outcomes, ArtiSential<sup>®</sup> LC showed better results in the respective visual analog scale (VAS) scores immediately after surgery (2.59 vs. 3.73, <i>p</i> < 0.001), and before discharge (1.44 vs. 2.02, <i>p</i> = 0.01).</p><p><strong>Conclusions: </strong>ArtiSential<sup>®</sup> LC showed better results in terms of surgical outcomes, especially postoperative pain. Thus, ArtiSential<sup>®</sup> LC is considered the better option for patients, compared to single-fulcrum LC.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on: "Deep learning-based surgical phase recognition in laparoscopic cholecystectomy". 评论"基于深度学习的腹腔镜胆囊切除术手术阶段识别
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-09-19 DOI: 10.14701/ahbps.24-149
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"Comment on: \"Deep learning-based surgical phase recognition in laparoscopic cholecystectomy\".","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.14701/ahbps.24-149","DOIUrl":"https://doi.org/10.14701/ahbps.24-149","url":null,"abstract":"","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of ergonomic positions to improve musculoskeletal distress in hepatobiliary pancreatic surgeons according to open, laparoscopic, and robotic surgeries. 根据开腹、腹腔镜和机器人手术,对改善肝胆胰外科医生肌肉骨骼不适的人体工程学体位进行回顾。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-09-09 DOI: 10.14701/ahbps.24-127
Young Jae Cho, Jin-Young Jang
{"title":"A review of ergonomic positions to improve musculoskeletal distress in hepatobiliary pancreatic surgeons according to open, laparoscopic, and robotic surgeries.","authors":"Young Jae Cho, Jin-Young Jang","doi":"10.14701/ahbps.24-127","DOIUrl":"https://doi.org/10.14701/ahbps.24-127","url":null,"abstract":"<p><p>Advances in surgical ergonomics are essential for the performance, health, and career longevity of surgeons. Many surgeons experience work-related musculoskeletal disorders (WMSDs) resulting from various surgical modalities, including open, laparoscopic, and robotic surgeries. To prevent WMSDs, individual differences may exist depending on the surgical method; however, the key is to maintain a neutral posture, and avoid static postures. This review aims to summarize the concepts of ergonomics and WMSDs; identify the ergonomic challenges of open, laparoscopic, and robotic surgeries; and discuss ergonomic recommendations to improve them.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of artificial intelligence in pancreatic surgery: Current and future perspectives. 人工智能在胰腺手术中的作用:当前和未来展望。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-09-04 DOI: 10.14701/ahbps.24-130
Alvaro Ducas, Alberto Mangano, Leonardo Borgioli, Jessica Cassiani, Paula Lopez, Pier Cristoforo Giulianotti
{"title":"The role of artificial intelligence in pancreatic surgery: Current and future perspectives.","authors":"Alvaro Ducas, Alberto Mangano, Leonardo Borgioli, Jessica Cassiani, Paula Lopez, Pier Cristoforo Giulianotti","doi":"10.14701/ahbps.24-130","DOIUrl":"https://doi.org/10.14701/ahbps.24-130","url":null,"abstract":"","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142128162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of neoadjuvant transarterial chemoembolization followed by resection versus upfront liver resection on the survival of single large hepatocellular carcinoma patients: A systematic review and meta-analysis. 新辅助经动脉化疗栓塞术后行切除术与先行肝切除术对单个大肝细胞癌患者生存期的影响:系统回顾和荟萃分析。
IF 1.1
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-08-31 Epub Date: 2024-05-13 DOI: 10.14701/ahbps.24-009
Indah Jamtani, Toar Jean Maurice Lalisang, Wawan Mulyawan
{"title":"Effect of neoadjuvant transarterial chemoembolization followed by resection versus upfront liver resection on the survival of single large hepatocellular carcinoma patients: A systematic review and meta-analysis.","authors":"Indah Jamtani, Toar Jean Maurice Lalisang, Wawan Mulyawan","doi":"10.14701/ahbps.24-009","DOIUrl":"10.14701/ahbps.24-009","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>The efficacy of neoadjuvant transarterial chemoembolization (N-TACE) in resectable hepatocellular carcinoma (HCC) remains open to debate. While N-TACE may reduce tumor size, its impact on long-term outcomes is inconclusive.</p><p><strong>Methods: </strong>This meta-analysis reviewed studies on N-TACE before surgical resection vs. liver resection (LR) single large hepatocellular carcinoma (SLHCC) up to March 2023 from four online databases.</p><p><strong>Results: </strong>Five studies with 1,556 patients were analyzed. No significant differences between N-TACE and LR groups were observed in 1-, 3-, or 5-year overall survival (OS) and disease-free survival (DFS). No significant differences were noted in intraoperative blood loss between groups. Subgroup analysis showed favorable 1-, 3-, and 5-year OS with combination chemotherapy N-TACE (combination group), and better 1-year OS in the LR group with single-agent chemotherapy N-TACE (single-agent group). Five-year DFS favored LR in the single-agent group, and N-TACE in the combination group.</p><p><strong>Conclusions: </strong>Managing SLHCC requires intricate considerations, and the treatment strategies for this challenging subgroup of HCC need to be improved. The influence of N-TACE on long-term survival depends on the specific chemotherapy regimen employed, and its impact on intraoperative blood loss in SLHCC appears limited.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11341878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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