Kim-Long Le, Tien-Quang Pham, Phu-Cuong Pham, Minh-Quang Tran, Tri-Nhan Pham, My-Tran Trinh, Nguyen-Khoi Le, Hai Van Nguyen
{"title":"Optimal timing of laparoscopic cholecystectomy after percutaneous gallbladder drainage in patients with acute calculous cholecystitis: A retrospective comparative study.","authors":"Kim-Long Le, Tien-Quang Pham, Phu-Cuong Pham, Minh-Quang Tran, Tri-Nhan Pham, My-Tran Trinh, Nguyen-Khoi Le, Hai Van Nguyen","doi":"10.14701/ahbps.25-062","DOIUrl":"https://doi.org/10.14701/ahbps.25-062","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Laparoscopic cholecystectomy (LC) is the standard therapy for acute calculous cholecystitis (ACC). However, high-risk patients often require percutaneous gallbladder drainage (PGBD) as a bridge to surgery. The optimal interval between PGBD and LC remains uncertain.</p><p><strong>Methods: </strong>We retrospectively reviewed 177 patients who underwent LC after PGBD for ACC at Nhan dan Gia Dinh Hospital (2018-2024). Patients were stratified by drainage-to-surgery interval: Q1, ≤ 9 days; Q2, 10-17 days; Q3, 18-32 days; Q4, ≥ 32 days. Primary outcomes were operative time, conversion, intraoperative bleeding, postoperative stay, and Clavien-Dindo complications. Multivariable logistic regression was performed after adjusting for age, Charlson Comorbidity Index (CCI), TG18 severity, sex, prior endoscopic retrograde cholangiopancreatography, and Concurrent PGBD and LC during the same admission.</p><p><strong>Results: </strong>Median operative time, conversion rate, and postoperative stay were similar across intervals. Crude bleeding differed significantly (<i>p</i> = 0.019), being the highest in Q4 (68.2%) and the lowest in Q2 (36.4%). Q3 showed the shortest operative time (median: 90 min) and the lowest complication rate (11.4%). In adjusted analysis, only CCI independently predicted bleeding (adjusted odds ratio: 1.42; 95% confidence interval: 1.02-2.03), while timing lost its statistical significance.</p><p><strong>Conclusions: </strong>Scheduling LC 18-32 days after PGBD offers the most balanced surgical profile, whereas delaying beyond 32 days increases bleeding without added benefit. Comorbidity burden rather than calendar interval per se appears to increase bleeding risk. Prospective studies are warranted to confirm the intermediate 2- to 4-week window.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gilbert Samuel Jebakumar, Siddhesh Tasgaonkar, Jeevanandham Muthiah, Gaurav Chinappa, Santhosh Anand K S, J K A Jameel, Tirupporur Govindaswamy Balachandar, Sudeepta Kumar Swain
{"title":"Feeding jejunostomy after pancreaticoduodenectomy: Benefit or burden?","authors":"Gilbert Samuel Jebakumar, Siddhesh Tasgaonkar, Jeevanandham Muthiah, Gaurav Chinappa, Santhosh Anand K S, J K A Jameel, Tirupporur Govindaswamy Balachandar, Sudeepta Kumar Swain","doi":"10.14701/ahbps.25-035","DOIUrl":"https://doi.org/10.14701/ahbps.25-035","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Pancreaticoduodenectomy (PD) is the standard treatment for resectable tumors of the pancreatic head, ampulla, distal bile duct, and duodenum. Despite advances, delayed gastric emptying (DGE) remains a common complication. Feeding jejunostomy (FJ) is often used during PD, though its necessity and association with increased morbidity, particularly DGE, remain controversial. This study aimed to evaluate early postoperative outcomes in PD patients with or without FJ, focusing on DGE and related complications.</p><p><strong>Methods: </strong>This prospective observational study was conducted from August 2022 to April 2024 and included 56 patients (28 with FJ, 28 without). Primary outcomes were DGE, postoperative pancreatic fistula (POPF), and hospital stay. Secondary outcomes included FJ-related complications, surgical site infections, and time to tolerate solid food. Statistical analysis was performed using SPSS v28.</p><p><strong>Results: </strong>DGE was significantly more frequent in the FJ group (78.6% vs. 39.3%, <i>p</i> = 0.006). Clinically relevant DGE (grades B/C) was also higher with FJ (60.7% vs. 21.4%, <i>p</i> = 0.008). FJ-related complications, including intestinal obstruction requiring reoperation, occurred in 10.7% of patients. Time to tolerate solid food and hospital stay were longer in the FJ group. Multivariate analysis identified FJ use and perioperative blood transfusion as independent risk factors for DGE.</p><p><strong>Conclusions: </strong>Routine FJ placement in PD is associated with increased DGE and tube-related complications. A selective approach to FJ may improve postoperative outcomes. Larger multicenter randomized trials are needed to validate these findings and develop clear guidelines for FJ use in PD.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paraphrases on postoperative outcomes in gallbladder cancer: Fundus and body vs. neck and cystic duct, a retrospective multicenter study.","authors":"Ilker Sengul, Demet Sengul","doi":"10.14701/ahbps.25-101","DOIUrl":"https://doi.org/10.14701/ahbps.25-101","url":null,"abstract":"","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reassessment of deep learning-based surgical phase recognition in laparoscopic cholecystectomy.","authors":"Ilker Sengul, Demet Sengul","doi":"10.14701/ahbps.25-059","DOIUrl":"https://doi.org/10.14701/ahbps.25-059","url":null,"abstract":"","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Freddy Pereira Graterol, Francisco Salazar Marcano, Yajaira Venales Barrios, Yeisson Rivero-Moreno, Dong Ki Lee
{"title":"Post-cholecystectomy total bile duct strictures: Cases for magnetic compression anastomosis.","authors":"Freddy Pereira Graterol, Francisco Salazar Marcano, Yajaira Venales Barrios, Yeisson Rivero-Moreno, Dong Ki Lee","doi":"10.14701/ahbps.24-186","DOIUrl":"10.14701/ahbps.24-186","url":null,"abstract":"<p><p>Bile duct injuries are a serious issue, and their surgical treatment carries the risk of morbidity and mortality. In selected cases, non-surgical treatments are possible, even for total strictures. We outline the technique and results of using magnetic compression anastomosis (MCA) to treat post-cholecystectomy bile duct stricture (PCBDS), in two female patients. Initially, a bilio-cutaneous tract was established via external biliary drainage, followed by the positioning of both endoscopic and percutaneous biliary magnets. After their approximation and subsequent removal, a fully covered self-expandable metal stent (FCSEMS) was deployed across the stricture. The magnet coupling was successfully achieved within the first two weeks of placement. The FCSEMS was maintained for durations of 12 and 16 months. Follow-up durations were 28 and 15 months post-FCSEMS removal. Both patients remain asymptomatic, with normal laboratory and imaging studies, and no adverse events were reported. MCA proves to be a safe and effective method for treating selected cases of total PCBDS. However, further studies and long-term follow-up are required to fully assess the efficacy of this technique.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"199-204"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peeyush Varshney, Saphalta Baghmar, Bhawna Sirohi, Ghassan K Abou-Alfa, Hop Tran Cao, Lalit Mohan Sharma, Milind Javle, Thorsten Goetze, Vinay K Kapoor
{"title":"Neoadjuvant treatment for incidental gallbladder cancer: A systematic review.","authors":"Peeyush Varshney, Saphalta Baghmar, Bhawna Sirohi, Ghassan K Abou-Alfa, Hop Tran Cao, Lalit Mohan Sharma, Milind Javle, Thorsten Goetze, Vinay K Kapoor","doi":"10.14701/ahbps.24-223","DOIUrl":"10.14701/ahbps.24-223","url":null,"abstract":"<p><p>Incidental gallbladder cancer (iGBC) diagnosed post-histopathological examination of gallbladders removed assuming benign gallstone disease constitutes a significant proportion of GBC patients. Most iGBC patients present with early-stage disease. The standard care for localized (non-metastatic) iGBC includes a reoperation for complete extended (radical) cholecystectomy involving liver resection and lymphadenectomy, followed by postoperative adjuvant systemic therapy. However, a major drawback of this approach is the high recurrence rate within six months post-radical surgery, which undermines the benefits of the extensive procedure; notably, most recurrences are distant, highlighting the efficacy of systemic therapy. Similar to other gastrointestinal cancers, there appears to be a potential for neoadjuvant systemic therapy (chemotherapy) before reoperative surgery in iGBC cases. The premise that neoadjuvant systemic therapy aids in selecting diseases with more favorable biological characteristics and addresses micro-metastatic disease appears applicable to iGBC as well. This systematic review examines the current evidence supporting or refuting neoadjuvant therapy and discusses criteria for selecting patients who would derive significant benefit, along with proposing an optimal chemotherapy regimen for iGBC patients. Improved outcomes have been reported in patients undergoing reoperation after 4 to 14 weeks following the initial cholecystectomy compared to immediate reoperation. Limited, yet promising, evidence supports the use of 3 to 4 cycles of gemcitabine-based neoadjuvant chemotherapy prior to reoperative surgery in select high-risk iGBC cases.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"113-120"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeong-Ik Park, Yong-Kyu Chung, Young Min Lee, Chang Woo Nam, Yang Won Nah
{"title":"Comparative analysis of postoperative outcomes of single-incision cholecystectomy: Propensity score matching of robotic surgery using the da Vinci SP system and da Vinci Xi system vs. laparoscopic surgery.","authors":"Jeong-Ik Park, Yong-Kyu Chung, Young Min Lee, Chang Woo Nam, Yang Won Nah","doi":"10.14701/ahbps.24-198","DOIUrl":"10.14701/ahbps.24-198","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>We compared the postoperative outcomes of single-incision laparoscopic cholecystectomy (SILC) with those of single-incision robotic cholecystectomy (SIRC) using the da Vinci Xi and SP systems.</p><p><strong>Methods: </strong>We retrospectively analyzed data from 206 patients who underwent these procedures by a single surgeon between August 2020 and April 2022. Propensity score matching was used to adjust for confounders and evaluate outcomes.</p><p><strong>Results: </strong>SILC exhibited shorter operation times compared to SIRC with Xi and SP (44.9 ± 14.5 min vs. 55.3 ± 12.2 min vs. 55.2 ± 16.2 min, <i>p</i> < 0.001). SIRC with Xi had shorter docking times (6.2 ± 2.8 min vs. 10.3 ± 2.3 min, <i>p</i> < 0.001), while SIRC with SP demonstrated reduced console times (11.2 ± 2.4 min vs. 18.6 ± 8.0 min, <i>p</i> < 0.001). Pain scores and complications did not significantly differ between the groups.</p><p><strong>Conclusions: </strong>Both SILC and SIRC showed comparable outcomes, with the SP system providing advantages such as reduced console time and fully articulated arms, likely reducing surgeon stress.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"140-149"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rodrigo Antonio Gasque, José Gabriel Cervantes, Magalí Chahdi Beltrame, Marcelo Enrique Lenz Virreira, Francisco Juan Mattera, Emilio Gastón Quiñonez
{"title":"\"Liver-loop\": A case report of an alternative modified liver hanging maneuver.","authors":"Rodrigo Antonio Gasque, José Gabriel Cervantes, Magalí Chahdi Beltrame, Marcelo Enrique Lenz Virreira, Francisco Juan Mattera, Emilio Gastón Quiñonez","doi":"10.14701/ahbps.24-217","DOIUrl":"10.14701/ahbps.24-217","url":null,"abstract":"<p><p>The liver hanging maneuver (LHM), introduced by Belghiti et al. in 2001, has been widely adapted to various hepatectomy techniques to reduce blood loss and facilitate parenchymal transection. However, its primary limitation is the risk of vascular injury, particularly near the inferior vena cava (IVC). In this report, we describe a modified \"Loop-Hanging\" maneuver designed as an alternative to enhance exposure during parenchymal transection and improve the control of Glissonean pedicles. In this case, we employed the technique during an open right hemihepatectomy on a 47-year-old male patient with a complex bile duct injury following two unsuccessful Roux-en-Y hepaticojejunostomies (RYHJ). The patient was referred to our institution due to an RYHJ stricture. Imaging identified a right hepatic artery pseudoaneurysm and a fistula to the biliary limb. After two failed attempts at endovascular embolization, a surgical approach was determined through multidisciplinary discussions. During the surgery, the liver was looped with a nasogastric tube positioned anterior to the IVC, allowing gentle upward traction that facilitated the transection, minimized bleeding, and enhanced pedicle control. The LHM is known to reduce blood loss but carries risks for patients with anatomical variations, scarring, or cirrhosis. Our \"Loop-Hanging\" technique retains the core advantages of LHM, simplifies the process, and diminishes the risk of vascular injury. Further research is required to assess its safety and broader applicability.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"187-191"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parenchymal-sparing non-anatomic resection vs. classic anatomic resection in colorectal cancer liver metastases.","authors":"Sungwon Jung","doi":"10.14701/ahbps.24-151","DOIUrl":"10.14701/ahbps.24-151","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Although anatomical liver resection is considered more effective in preventing complications and recurrence in hepatocellular carcinoma, its efficacy has yet to be clearly defined in colorectal cancer liver metastasis (CLM).</p><p><strong>Methods: </strong>From January 2000 to December 2023, 145 patients underwent liver resections for CLM, divided into anatomic and non-anatomic resection cohorts. The dataset included demographic details, tumor size, number and distribution of metastases, neoadjuvant chemotherapy, primary tumor location and stage, type of liver surgery, transfusion rates, duration of hospital stay, postoperative complications, and completeness of resection.</p><p><strong>Results: </strong>Of the 145 patients who underwent liver resections for metastases from colorectal cancer, 62 were in the anatomic group and 83 were in the non-anatomic group. The anatomic group had larger tumors (6.71 cm vs. 3.18 cm). Intraoperative transfusion rates were higher in the anatomic group (56.5% vs. 12.0%). Hospital stays, positive resection margin rates, and postoperative complication rates showed no significant differences. One surgery-related death occurred in the anatomic group. Disease-free and overall survival rates were comparable between groups.</p><p><strong>Conclusions: </strong>Anatomic liver resection did not demonstrate a reduction in recurrence or an improvement in survival rates compared to non-anatomic resection. As such, anatomical resection does not offer a <i>survival</i> advantage over non-anatomical resection. Consequently, surgical method selection should prioritize patient safety, preservation of residual liver parenchyma, and tumor-specific factors.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"121-126"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heterotopic pancreas of the gallbladder: A case report of a rare and commonly incidental finding.","authors":"Nelson Chen, Jessica Gu","doi":"10.14701/ahbps.24-190","DOIUrl":"10.14701/ahbps.24-190","url":null,"abstract":"<p><p>Heterotopic pancreas (HP) refers to the presence of ectopic pancreatic tissue located outside of the normal pancreatic location without anatomical or vascular continuity with the pancreas. HP within the gallbladder (HPGB) was first described by Otschkin in 1916. It remains an exceedingly rare pathology with few reported cases. Here we describe a case of HPGB in a 42-year-old female following laparoscopic cholecystectomy for symptoms of biliary colic. She presented with epigastric pain, elevated levels in liver function tests, and gallbladder sludge on ultrasound. Her lipase and bilirubin levels were within normal limits. Histopathological assessment of the gallbladder identified mild chronic cholecystitis and pancreatic heterotopia adjacent to the cystic duct of the gallbladder with all three elements (ducts, acini, and endocrine islets) of the pancreas, consistent with type 1 based on the classification of Gaspar Fuentes et al. HPGB is often diagnosed incidentally during histopathological examination after cholecystectomy. Preoperative diagnosis is challenging due to its rarity. It is thought to be asymptomatic. Although the clinical significance of HPGB remains uncertain, it has been hypothesized that HPGB can cause acalculous cholecystitis and also have the potential for malignant transformation. Our case supports the theory that the exocrine function of an ectopic pancreatic tissue may contribute to chronic inflammation in the gallbladder. In conclusion, although HPGB is a rare finding with unclear clinical relevance, its potential for malignancy and association with cholecystitis warrant further investigation. Given its scarcity, most knowledge about HPGB comes from case reports and case series. This report adds to the existing literature.</p>","PeriodicalId":72220,"journal":{"name":"Annals of hepato-biliary-pancreatic surgery","volume":" ","pages":"205-208"},"PeriodicalIF":1.1,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}