Advanced Composites and Hybrid Materials最新文献

筛选
英文 中文
In situ cell condensation-based cartilage tissue engineering via immediately implantable high-density stem cell core and rapidly degradable shell microgels 基于即刻植入的高密度干细胞核心和可快速降解的壳微凝胶的原位细胞凝聚软骨组织工程
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-12 DOI: 10.1007/s42114-025-01406-x
Sang Jin Lee, Oju Jeon, Yu Bin Lee, Daniel S. Alt, Aixiang Ding, Rui Tang, Eben Alsberg
{"title":"In situ cell condensation-based cartilage tissue engineering via immediately implantable high-density stem cell core and rapidly degradable shell microgels","authors":"Sang Jin Lee,&nbsp;Oju Jeon,&nbsp;Yu Bin Lee,&nbsp;Daniel S. Alt,&nbsp;Aixiang Ding,&nbsp;Rui Tang,&nbsp;Eben Alsberg","doi":"10.1007/s42114-025-01406-x","DOIUrl":"10.1007/s42114-025-01406-x","url":null,"abstract":"<p>Formation of chondromimetic human mesenchymal stem cell (hMSC) condensations typically requires in vitro culture in defined environments. In addition, extended in vitro culture in differentiation media over several weeks is usually necessary prior to implantation, which is costly, time consuming, and delays clinical treatment. Here, this study reports on immediately implantable core/shell microgels with a high-density hMSC-laden core and rapidly degradable hydrogel shell. The hMSCs in the core-formed cell condensations within 12 h and the oxidized and methacrylated alginate (OMA) hydrogel shells were completely degraded within 3 days, enabling spontaneous and precipitous fusion of adjacent condensed aggregates. By delivering transforming growth factor-β1 (TGF-β1) within the core, the fused condensates were chondrogenically differentiated and formed cartilage-like microtissues. Importantly, these hMSC-laden core/shell microgels, fabricated without any in vitro culture, were subcutaneously implanted into mice and shown to form cartilage-like tissue via cellular condensations in the core after 3 weeks. This innovative approach to form cell condensations in situ without in vitro culture that can fuse together with each other and with host tissue and mature into new tissue with incorporated bioactive signals allows for immediate implantation and may be a platform strategy for cartilage regeneration and other tissue engineering applications.\u0000</p>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01406-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144814374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound-activated dual-nanozyme platform for targeted ROS scavenging and NO delivery in liver fibrosis therapy 肝纤维化治疗中靶向ROS清除和NO递送的超声激活双纳米酶平台
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-12 DOI: 10.1007/s42114-025-01411-0
Xiujuan Yin, Shuqin Xue, Jiaqi Ji, Mingyu Zhao, Min Shao, Likang Yin, Saisai Zhang, Lei Liu, Bin Li, Lei Zhang, Yuan Li, Xiao Wang
{"title":"Ultrasound-activated dual-nanozyme platform for targeted ROS scavenging and NO delivery in liver fibrosis therapy","authors":"Xiujuan Yin,&nbsp;Shuqin Xue,&nbsp;Jiaqi Ji,&nbsp;Mingyu Zhao,&nbsp;Min Shao,&nbsp;Likang Yin,&nbsp;Saisai Zhang,&nbsp;Lei Liu,&nbsp;Bin Li,&nbsp;Lei Zhang,&nbsp;Yuan Li,&nbsp;Xiao Wang","doi":"10.1007/s42114-025-01411-0","DOIUrl":"10.1007/s42114-025-01411-0","url":null,"abstract":"<div><p>Liver fibrosis (LF) is a leading cause of liver-related mortality worldwide. Although antifibrotic drugs are commonly used in clinical practice, their efficacy remains limited. Excessive reactive oxygen species (ROS) in the fibrotic liver microenvironment play a crucial role in LF progression. Nanozymes, owing to their enzyme-mimicking catalytic activity and antioxidant properties, offer a promising strategy for LF treatment. Vanadium-based nanozymes exhibit ROS-scavenging capabilities and promote fibrosis reversal, while zirconium (Zr)-based metal–organic frameworks (MOFs), such as UiO-66, possess excellent biocompatibility and catalytic activity. However, the therapeutic efficacy of nanozymes is hindered by their intrinsic catalytic limitations. Ultrasound (US), a non-invasive therapeutic modality, has been shown to enhance nanozyme activity and improve treatment outcomes. In this study, we developed a dual-nanozyme composite (UiO-66/V<sub>2</sub>C/L-Arg/pPB, UVLp) with targeted ROS-scavenging and L-arginine (L-Arg) delivery capabilities. Upon ultrasound exposure, UVLp releases L-Arg and nanozymes, facilitating nitric oxide (NO) generation, alleviating oxidative stress, and mitigating liver fibrosis. This work introduces a novel ultrasound-activated nanozyme platform for LF therapy, providing valuable insights for clinical translation.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01411-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144814375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular template engineering hierarchical porous Fe–N-C with tunable Fe3O4 particle size for efficient oxygen reduction reaction 具有可调Fe3O4粒径的分子模板工程分级多孔Fe-N-C用于高效氧还原反应
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-12 DOI: 10.1007/s42114-025-01407-w
Lijuan Wang, Yaqin Shi, Yuan Wang, Chunijang Jia, Jie Hou, Yizhen Su, Ben Bin Xu, Zhijian Liao, Linhua Zhu
{"title":"Molecular template engineering hierarchical porous Fe–N-C with tunable Fe3O4 particle size for efficient oxygen reduction reaction","authors":"Lijuan Wang,&nbsp;Yaqin Shi,&nbsp;Yuan Wang,&nbsp;Chunijang Jia,&nbsp;Jie Hou,&nbsp;Yizhen Su,&nbsp;Ben Bin Xu,&nbsp;Zhijian Liao,&nbsp;Linhua Zhu","doi":"10.1007/s42114-025-01407-w","DOIUrl":"10.1007/s42114-025-01407-w","url":null,"abstract":"<div><p>Synergistic effect between M-N<sub>X</sub> sites and M<sub>X</sub>O<sub>Y</sub> particles in hierarchical porous M–N-C catalysts holds great promises in boosting oxygen reduction reaction (ORR). In this work, 1,4-dicyanobenzene was utilized as a molecular template to prepare the hierarchical porous Fe–N-C catalysts with size-tunable Fe<sub>3</sub>O<sub>4</sub> particles for enhanced ORR in Zn-air battery. The as-prepared Fe<sub>3</sub>O<sub>4</sub>#Fe–N/C<sub>DB0.1</sub> owned a half-potential of 0.90 V vs RHE, exceeding that of commercial 20%Pt/C (E<sub>1/2</sub> = 0.82 V vs RHE), showing a maximum power density of 321 mW cm<sup>−2</sup> in a homemade Zn-air battery. Density functional theory (DFT) calculations indicate that the electronic interaction between Fe<sub>3</sub>O<sub>4</sub> and Fe-N<sub>4</sub> sites enhances the adsorption energy of *OOH, effectively optimizing the energy barrier for *O formation, significantly reducing the limiting energy barrier. Such superior ORR activity in Fe<sub>3</sub>O<sub>4</sub>#Fe–N/C originated from the optimized hierarchical pores and synergistic effect between Fe-N<sub>X</sub> sites and Fe<sub>3</sub>O<sub>4</sub> particles. This work provides a new and facile template strategy for engineering hierarchical porous carbon-based materials to achieve highly efficient catalytic reactions.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01407-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144814376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multifunctional antimonene-gold nanocomposites for fluorescence sensing of exosomes and metal ions, molecular information encoding and protection 外泌体和金属离子荧光传感、分子信息编码和保护的多功能锑金纳米复合材料
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-11 DOI: 10.1007/s42114-025-01334-w
Jiao Yang Lu, Zhi Xin Xie, Jie Zhou, Meng Yao Wu, Yu Qing Tian, Tian Tian Fu, Dong Hua Wang, Bin Sheng He, Wei Tao Huang
{"title":"Multifunctional antimonene-gold nanocomposites for fluorescence sensing of exosomes and metal ions, molecular information encoding and protection","authors":"Jiao Yang Lu,&nbsp;Zhi Xin Xie,&nbsp;Jie Zhou,&nbsp;Meng Yao Wu,&nbsp;Yu Qing Tian,&nbsp;Tian Tian Fu,&nbsp;Dong Hua Wang,&nbsp;Bin Sheng He,&nbsp;Wei Tao Huang","doi":"10.1007/s42114-025-01334-w","DOIUrl":"10.1007/s42114-025-01334-w","url":null,"abstract":"<div><p>Inspired by the emergent functions of molecular interactions and signal processing networks in living systems, exploring the multifunctional properties and perceptual capabilities of molecular or nanosystems and digitizing their signal responses and interaction networks remains a key challenge. Here, multifunctional antimonene-gold nanocomposites (AM-Au NCs) were synthesized efficiently and conveniently and applied in molecular sensing and digital applications, including multi-component detection and multi-coding information protection. After mixing surfactant, AM, Au<sup>3</sup>⁺ and NaBH₄, AM-Au NCs with dispersed Au nanoparticles on AM nanosheets, exhibiting prominent Au plasmonic absorption. This endows NCs with unique broad-spectrum fluorescence quenching abilities, facilitating the development of fluorescence sensing platforms with dyes and fluorescence-labeled aptamers for selective and sensitive detection of metal ions and tumor biomarkers (CD63 and tumor-derived exosomes), even in real samples. Through binary or digital encoding of the selective responses and diverse DNA sequences of these sensing systems, a series of molecular encryption and hiding techniques are presented and applied to the molecular-level conservation of special text information. This work provides a new framework for the preparation and multifunctional use of two-dimensional nanocomposites, paving the way for greater integration of molecular sensing and information technology.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01334-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Boosting peroxymonosulfate activation over cyanuric acid-modified Co3O4@Fe2O3 for tetracycline degradation: insights into catalytic performance, degradation mechanism, and routes 促进过氧单硫酸盐活化在氰尿酸修饰Co3O4@Fe2O3四环素降解:洞察催化性能,降解机制和途径
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-09 DOI: 10.1007/s42114-025-01381-3
Geng Li, Guangyu Wu, Wenting Sun, Shiyu Bian, Yuwei Pan, Weinan Xing, Jiangang Han, Ming Zhang, Yudong Huang
{"title":"Boosting peroxymonosulfate activation over cyanuric acid-modified Co3O4@Fe2O3 for tetracycline degradation: insights into catalytic performance, degradation mechanism, and routes","authors":"Geng Li,&nbsp;Guangyu Wu,&nbsp;Wenting Sun,&nbsp;Shiyu Bian,&nbsp;Yuwei Pan,&nbsp;Weinan Xing,&nbsp;Jiangang Han,&nbsp;Ming Zhang,&nbsp;Yudong Huang","doi":"10.1007/s42114-025-01381-3","DOIUrl":"10.1007/s42114-025-01381-3","url":null,"abstract":"<div><p>Photocatalytic technology combined with peroxomonosulfate (PMS) advanced oxidation shows significant potential for effectively treating various challenging pollutants. In recent years, vacancy engineering has received widespread attention due to its unique electronic structure and is also considered an effective way in enhancing catalytic performance. In this work, Co-Fe bimetallic oxide composite with oxygen vacancy (O<sub>v</sub>)–rich structure (L-Co<sub>3</sub>O<sub>4</sub>@Fe<sub>2</sub>O<sub>3</sub>) was constructed using in situ growth and modified with cyanuric acid etching to enhance dual synergistic photocatalysis and PMS activation. The findings demonstrated that the L-Co<sub>3</sub>O<sub>4</sub>@Fe<sub>2</sub>O<sub>3</sub>/PMS/UV-LED system achieved a removal rate of 99.4% tetracycline (TC) within 30 min, surpassing that of Co<sub>3</sub>O<sub>4</sub>@Fe<sub>2</sub>O<sub>3</sub>/PMS/UV-LED system. The presence of PMS as a Lewis base was found to expedite charge separation kinetics, leading to the generation of SO<sub>4</sub><sup>•−</sup> and <sup>•</sup>OH radicals and enabling direct TC oxidation by efficiently separated holes. In combination with DFT calculations, the polarization properties and electric field effects of TC molecule were predicted using HOMO, LUMO, and Fukui indices. Notably, 15 intermediates were identified within this system, facilitating the accurate deduction of TC degradation pathways. This research not only introduces a novel modification strategy for developing cost-effective and environmentally friendly catalysts featuring O<sub>v</sub> but also enhances the understanding of persulfate activation mechanisms with metal-based materials.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01381-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145143007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrastretchable, fatigue-resistant eutectogel with hierarchical bonding for advanced wearable monitoring 超伸缩,抗疲劳共tectol与分层粘合先进的可穿戴监测
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-08 DOI: 10.1007/s42114-025-01395-x
Min Jeong Kim, Sung Ho Cho, Soong Ju Oh, Sang Woo Kim
{"title":"Ultrastretchable, fatigue-resistant eutectogel with hierarchical bonding for advanced wearable monitoring","authors":"Min Jeong Kim,&nbsp;Sung Ho Cho,&nbsp;Soong Ju Oh,&nbsp;Sang Woo Kim","doi":"10.1007/s42114-025-01395-x","DOIUrl":"10.1007/s42114-025-01395-x","url":null,"abstract":"<div><p>Wearable healthcare and IoT systems require conductors that are highly stretchable, skin-conformal, and capable of stable sensing under dynamic mechanical stress. However, conventional ionic conductors—such as hydrogels and eutectogels—often suffer from low ionic conductivity, poor fatigue resistance, and mechanical fragility due to inherent trade-offs between electrical and mechanical properties. Here, we present an ultrastretchable, fatigue-resistant organic mixed ionic–electronic conductor (OMIEC) eutectogel, engineered via a hierarchical bonding architecture. This design integrates dynamic hydrogen bonding within a polymerizable deep eutectic solvent (PDES) matrix and hydrophobic interactions from embedded PEDOT-based conductive domains. The synergistic interplay between these networks significantly enhances mechanical toughness, fracture resistance, electrical conductivity, and electromechanical sensitivity. The eutectogel demonstrates a 66-fold increase in conductivity, a 6.2-fold enhancement in fracture energy, and a 4.5-fold improvement in toughness compared to conventional ionic conductors, while maintaining ultralow electromechanical hysteresis (≤ 1%) under strains of up to 1,500%. Furthermore, the material exhibits autonomous self-healing and retains its functionality more than 100,000 stretch–release cycles. These multifunctional properties enable precise and robust monitoring of physiological motion, temperature variation, and complex human gestures under diverse mechanical stimuli and dynamic environmental conditions. The proposed OMIEC eutectogel thus represents a promising platform for next-generation wearable electronics in healthcare, soft robotics, and IoT applications.\u0000</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01395-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145142826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent progress in two-dimensional van der Waals heterojunctions for flexible energy storage applications 二维范德华异质结柔性储能研究进展
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-08 DOI: 10.1007/s42114-025-01410-1
Ting Ding, Xupu Jiang, Jiaxin Quan, Rui Wang, Min Li, Chuntao Lan, Wujun Ma, Meifang Zhu
{"title":"Recent progress in two-dimensional van der Waals heterojunctions for flexible energy storage applications","authors":"Ting Ding,&nbsp;Xupu Jiang,&nbsp;Jiaxin Quan,&nbsp;Rui Wang,&nbsp;Min Li,&nbsp;Chuntao Lan,&nbsp;Wujun Ma,&nbsp;Meifang Zhu","doi":"10.1007/s42114-025-01410-1","DOIUrl":"10.1007/s42114-025-01410-1","url":null,"abstract":"<div><p>Two-dimensional van der Waals heterojunctions (2D vdWHs) have emerged as promising materials for next-generation flexible energy storage devices. Their unique physicochemical properties and interface engineering capabilities drive this potential. This comprehensive review systematically analyzes the recent developments in 2D vdWHs, focusing on their fundamental principles, fabrication methodologies, and applications in flexible energy storage systems. We first introduce the background of vdWHs and discuss four main synthesis strategies: direct stacking, chemical vapor deposition (CVD), in situ growth, and solution processing techniques. The review then extensively examines their applications in various flexible energy storage devices, including supercapacitors, lithium-ion batteries, zinc-ion batteries, and emerging storage systems such as potassium-ion, sodium-ion, and metal-air batteries. The review emphasizes the crucial role of heterojunction interfaces. These interfaces enhance electrochemical performance by improving charge transfer kinetics and maintaining structural stability. The superior performance of these materials is attributed to their large interfacial contact areas, synergistic effects between components, and optimized electron/ion transfer pathways. Despite significant progress, challenges remain in interface stability, scalable production, and performance optimization. We conclude by discussing future research directions, including novel materials development, advanced fabrication technologies, and emerging applications beyond energy storage. This review provides valuable insights for researchers working on next-generation flexible energy storage devices and highlights the transformative potential of 2D vdWHs in practical applications.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01410-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145142827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Bio-inspired design of antifouling polymeric coatings with natural extracts: key evidence for resistance to fouling adhesion 更正:生物灵感设计的防污聚合物涂料与天然提取物:关键证据,以抵抗污垢粘附
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-08 DOI: 10.1007/s42114-025-01363-5
Min Liu, Weihua Mao, Mai Zhang, Shuyi Huang, Shishi Lin, Jianjun Liao, Ping Zhang, Linlin Zhang
{"title":"Correction: Bio-inspired design of antifouling polymeric coatings with natural extracts: key evidence for resistance to fouling adhesion","authors":"Min Liu,&nbsp;Weihua Mao,&nbsp;Mai Zhang,&nbsp;Shuyi Huang,&nbsp;Shishi Lin,&nbsp;Jianjun Liao,&nbsp;Ping Zhang,&nbsp;Linlin Zhang","doi":"10.1007/s42114-025-01363-5","DOIUrl":"10.1007/s42114-025-01363-5","url":null,"abstract":"","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01363-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145142494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progress in the integration of 3D printing technology with photothermal materials for osteosarcoma treatment 3D打印技术与光热材料融合治疗骨肉瘤的进展
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-08 DOI: 10.1007/s42114-025-01405-y
Yue Zheng, Hanqi Lou, Zhen Gao, Ling Zhu, Yiwei Zhang, Haiyang Lin, Zilin Li, Xiaokun Yue, Weize Kong, Hao Yang, Zhouhao Chen, Zhiang Hu, Xin Liu, Xinming Su, Jinwu Wang, Junjie Niu
{"title":"Progress in the integration of 3D printing technology with photothermal materials for osteosarcoma treatment","authors":"Yue Zheng,&nbsp;Hanqi Lou,&nbsp;Zhen Gao,&nbsp;Ling Zhu,&nbsp;Yiwei Zhang,&nbsp;Haiyang Lin,&nbsp;Zilin Li,&nbsp;Xiaokun Yue,&nbsp;Weize Kong,&nbsp;Hao Yang,&nbsp;Zhouhao Chen,&nbsp;Zhiang Hu,&nbsp;Xin Liu,&nbsp;Xinming Su,&nbsp;Jinwu Wang,&nbsp;Junjie Niu","doi":"10.1007/s42114-025-01405-y","DOIUrl":"10.1007/s42114-025-01405-y","url":null,"abstract":"<div><p>Osteosarcoma, a highly aggressive primary bone malignancy, presents poor prognosis in metastatic or recurrent cases, driving demand for innovative therapies. Photothermal therapy (PTT) emerges as a promising tumor ablation method due to its minimally invasive, selective nature. Combined with three-dimensional (3D)-printed scaffolds, PTT enables precise photothermal agent delivery and spatial alignment with laser irradiation, synergizing tumor eradication and bone repair. These customizable scaffolds adapt to bone defect morphology, offering antitumor activity, osteoinduction, and anti-inflammatory/antibacterial functions to mitigate postoperative complications. Though nascent, this multimodal approach holds significant therapeutic potential. This review introduces 3D-printed photothermal materials used in osteosarcoma treatment, including metallic and metal-derived photothermal materials, inorganic non-metallic photothermal materials, and polymer-based composite photothermal materials. It also discusses the 3D printing technologies applied to these materials, such as extrusion-based 3D printing and powder bed fusion 3D printing. The therapeutic effects of these materials are summarized from four dimensions: antitumor mechanisms, bone regeneration efficacy, and anti-inflammatory and antibacterial actions. By integrating existing research findings, this article aims to provide a theoretical basis and technical roadmap for developing intelligent scaffolds that combine precise tumor treatment with functional bone repair, thereby promoting innovative breakthroughs in comprehensive osteosarcoma treatment strategies.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01405-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145142825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanoporous/nanofibrous dual-aerogel ultraflexible ceramic coatings for fire superprotection 纳米多孔/纳米纤维双气凝胶超柔陶瓷防火涂料
IF 21.8 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-08-08 DOI: 10.1007/s42114-025-01416-9
Cong Li, Dizhou Liu, Hongxuan Yu, Han Zhao, Jingran Guo, Chuanyun Song, Yingde Zhao, Jianing Zhang, Yuanpeng Deng, Shixuan Dang, Duola Wang, Jiali Chen, Zhengli Yan, Tiande Lin, Hui Li, Xiang Xu
{"title":"Nanoporous/nanofibrous dual-aerogel ultraflexible ceramic coatings for fire superprotection","authors":"Cong Li,&nbsp;Dizhou Liu,&nbsp;Hongxuan Yu,&nbsp;Han Zhao,&nbsp;Jingran Guo,&nbsp;Chuanyun Song,&nbsp;Yingde Zhao,&nbsp;Jianing Zhang,&nbsp;Yuanpeng Deng,&nbsp;Shixuan Dang,&nbsp;Duola Wang,&nbsp;Jiali Chen,&nbsp;Zhengli Yan,&nbsp;Tiande Lin,&nbsp;Hui Li,&nbsp;Xiang Xu","doi":"10.1007/s42114-025-01416-9","DOIUrl":"10.1007/s42114-025-01416-9","url":null,"abstract":"<p>Advanced fire protection for infrastructures and facilities requires fireproof coatings that can possess high fire resistance, thermal insulation, flexibility, and durability. Conventional coatings are usually developed by composing inorganic fillers and organic binders, still suffering from limited fireproof effect, severe fracture, and short working life. Here, we report a dual-aerogel design of robust aluminosilicate ceramic coating with natural-dried nanoporous aerogel for thermal insulation and electro-spun nanofibrous aerogel for flexible deformation. The resulting coating, with a thickness of only 3 mm, exhibits a fire superprotection performance with fire resistance up to 1400 °C, thermal conductivity of only 103.55 mW·m<sup>−1</sup>·K<sup>−1</sup> at 1000 °C, hydrophobicity of contact angle up to 154°, and ultraflexibility of a 90° bending angle with 10,000 times of fatigue resistance. This unique dual-aerogel design can well resolve the formidable thermal–mechanical trade-off in fireproof coatings and establish a set of fundamental considerations in material design for fire superprotection.\u0000</p>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 4","pages":""},"PeriodicalIF":21.8,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01416-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145142828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信