Analysis & sensing最新文献_第9页

Wearable Electrodes for Lactate: Applications in Enzyme-Based Sensors and Energy Biodevices 乳酸可穿戴电极：在基于酶的传感器和能量生物设备中的应用

Analysis & sensing Pub Date : 2023-01-13 DOI: 10.1002/anse.202200066

Natcha Rasitanon, Dr. Sirawit Ittisoponpisan, Kanyawee Kaewpradub, Dr. Itthipon Jeerapan

{"title":"Wearable Electrodes for Lactate: Applications in Enzyme-Based Sensors and Energy Biodevices","authors":"Natcha Rasitanon, Dr. Sirawit Ittisoponpisan, Kanyawee Kaewpradub, Dr. Itthipon Jeerapan","doi":"10.1002/anse.202200066","DOIUrl":"https://doi.org/10.1002/anse.202200066","url":null,"abstract":"Wearable bioelectronics is a promising next-generation technology for its versatility in personalized applications. Measuring lactate is one of the growing trends in wearable biosensing research. To achieve this goal, enzymes capable of catalyzing reactions involving lactate must be coupled with bioelectrode components, creating a variety of biodevices such as biosensors, biofuel cells, and other devices harvesting energy from wearers. This review provides a brief history of noninvasive and minimally invasive enzyme-based lactate biosensors and energy biodevices. We introduce key principles of lactate oxidase and lactate dehydrogenase, together with immobilization strategies for efficient electrical contacts between redox enzymes and electrode supports. Additionally, we discuss recent examples of advanced wearable enzymatic lactate sensors and elaborate on a collection of self-powered wearable energy biodevices (e. g., biofuel cells, triboelectric nanogenerators, and piezoelectric devices). Lastly, we finish this review with discussions on challenges in developing lactate bioelectronics and provide our outlook on the prospects and future directions of this compelling technology.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50140389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Pushing Differential Sensing Further: The Next Steps in Design and Analysis of Bio-Inspired Cross-Reactive Arrays 进一步推动差分传感：生物激励交叉反应阵列设计和分析的下一步

Analysis & sensing Pub Date : 2023-01-10 DOI: 10.1002/anse.202200095

Dr. Hazel A. Fargher, Dr. Simon d'Oelsnitz, Daniel J. Diaz, Prof. Eric V. Anslyn

引用次数: 0

Sensitive Detection of p-Chlorobenzaldehyde in Environmental Water Based on Au@Ag-MOFs Nanoparticle by Surface-Enhanced Raman Scattering 基于Au@Ag-MOFs纳米粒子表面增强拉曼散射的环境水中对氯苯甲醛的灵敏检测

Analysis & sensing Pub Date : 2023-01-10 DOI: 10.1002/anse.202200108

Dr. Yuanting Li, Mengmeng Zhang, Zhouya Wu, Dr. Xiaoli Bao

{"title":"Sensitive Detection of p-Chlorobenzaldehyde in Environmental Water Based on Au@Ag-MOFs Nanoparticle by Surface-Enhanced Raman Scattering","authors":"Dr. Yuanting Li, Mengmeng Zhang, Zhouya Wu, Dr. Xiaoli Bao","doi":"10.1002/anse.202200108","DOIUrl":"https://doi.org/10.1002/anse.202200108","url":null,"abstract":"Surface enhanced Raman scattering (SERS) is difficult to detect molecules with weak adsorption, like aldehydes. Herein, we fabricated core-shell Au@Ag-MOFs nanoparticles as SERS substrate. The shell can be controllably synthesized, with the thickness about 3 nm. After the morphology and SERS activity characterization, Au@Ag-MOFs were employed to sensitive and label-free detect p-chlorobenzaldehyde (PCB) in water samples. The pore structure and large surface area of Ag-MOFs shell results more adsorption of PCB, dragging more molecules to “hot spots” area. The abundant amino group in Ag-MOFs allows the occurrence of Schiff base reaction with aldehyde group in PCB. Taking the synergistic effect of both physical and chemical enhancement, SERS signals of PCB were greatly boosted. The method showed good linearity between 5.0×10−12 M to 1.0×10−8 M for PCB with the limit of detection (LOD) down to 3.3×10−12 M. The proposed method has great potential to be a reliable analytical strategy for aldehydes in real samples.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109166978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are Phosphatidic Acids Ubiquitous in Mammalian Tissues or Overemphasized in Mass Spectrometry Imaging Applications? 磷脂酸在哺乳动物组织中普遍存在还是在质谱成像应用中被过度强调？

Analysis & sensing Pub Date : 2023-01-09 DOI: 10.1002/anse.202200112

Gregory W. Vandergrift, Jessica K. Lukowski, Michael J. Taylor, Kevin J. Zemaitis, Theodore Alexandrov, Josie G. Eder, Heather M. Olson, Jennifer E. Kyle, Christopher Anderton

{"title":"Are Phosphatidic Acids Ubiquitous in Mammalian Tissues or Overemphasized in Mass Spectrometry Imaging Applications?","authors":"Gregory W. Vandergrift, Jessica K. Lukowski, Michael J. Taylor, Kevin J. Zemaitis, Theodore Alexandrov, Josie G. Eder, Heather M. Olson, Jennifer E. Kyle, Christopher Anderton","doi":"10.1002/anse.202200112","DOIUrl":"https://doi.org/10.1002/anse.202200112","url":null,"abstract":"Mass spectrometry imaging (MSI) is an invaluable tool for the spatial visualization of molecules in vivo. However, the question of whether observed annotations are endogenous or artificial (i. e., from in-source fragmentation) is critical and has been largely unexplored in multimodal MSI. In matrix-assisted laser desorption/ionization (MALDI)-MSI datasets from researchers worldwide, PAs were found to represent up to 18 % of annotations in rat brain. Rat brain was additionally imaged here using nanospray desorption electrospray ionization (nano-DESI), a softer ionization strategy. No PAs observed with MALDI were present in the nano-DESI dataset. Further investigation strongly indicated lipid fragmentation to PAs for MALDI-MSI, but not with nano-DESI-MSI. We finally extend this observation to the MALDI-MSI analyses of human tissues, showing that PA annotations comprised up to 16 % of annotations. Therefore, this study shows that MSI annotations should be carefully interrogated, as in-source fragmentation or modification of lipids may contribute substantially to false annotations and incorrect biological interpretations.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202200112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50136194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

ATR-FTIR Spectroscopy for Early Detection of Diabetic Kidney Disease ATR-FTIR光谱早期检测糖尿病肾病

Analysis & sensing Pub Date : 2022-12-27 DOI: 10.1002/anse.202200094

Zack Richardson, Adele Kincses, Prof. Elif Ekinci, Dr. David Perez-Guaita, Prof. Karin Jandeleit-Dahm, Prof. Bayden R. Wood

{"title":"ATR-FTIR Spectroscopy for Early Detection of Diabetic Kidney Disease","authors":"Zack Richardson, Adele Kincses, Prof. Elif Ekinci, Dr. David Perez-Guaita, Prof. Karin Jandeleit-Dahm, Prof. Bayden R. Wood","doi":"10.1002/anse.202200094","DOIUrl":"https://doi.org/10.1002/anse.202200094","url":null,"abstract":"Current screening methods for diabetic kidney disease (DKD), characterized by albumin excretion in urine, are expensive or only identify patients in late disease stages. Hence, there is need for a cost-effective, quick, and portable screening tool which identifies patients at DKD onset. Here we report that ultracentrifugation coupled with infrared spectroscopy and machine learning can identify and quantify low level microalbuminuria in urine samples from a cohort of diabetic patients (n=155) and controls (n=22). Independent testing of the methods indicated that classification analysis discriminated between normo- and micro/macroalbuminuric samples with sensitivity of >91 % and specificity of >99 %. Regression methods quantified albumin concentration in the samples with error values of 17 and 44 mg/L for normo- and microalbuminuric patients. Using only 700 μL of sample, this approach identifies patients at an earlier stage of disease than a urinary dipstick, whilst also yielding results cheaper and faster than the albumin to creatinine ratio.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202200094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50145182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Near-Infrared Spectroscopic Characterization of Cardiac and Renal Fibrosis in Fixed and Fresh Rat Tissue 固定和新鲜大鼠组织中心脏和肾脏纤维化的近红外光谱特征

Analysis & sensing Pub Date : 2022-12-13 DOI: 10.1002/anse.202200106

John A. Adegoke, Callum Gassner, Dr. Varun J. Sharma, Dr. Sheila K. Patel, Dr. Louise Jackett, Dr. Isaac O. Afara, Prof. Jaishankar Raman, Prof. Louise M. Burrell, Prof. Bayden R. Wood

引用次数: 0

Lipid Analysis by Mass Spectrometry coupled with Laser Light 质谱联用激光分析脂质

Analysis & sensing Pub Date : 2022-12-13 DOI: 10.1002/anse.202200103

Carla Kirschbaum, Kevin Pagel

引用次数: 2

Front Cover: Near-Infrared Spectroscopic Characterization of Cardiac and Renal Fibrosis in Fixed and Fresh Rat Tissue (Anal. Sens. 1/2023) 封面：固定和新鲜大鼠组织中心脏和肾脏纤维化的近红外光谱特征（Anal.Sens.1/2023）

Analysis & sensing Pub Date : 2022-12-12 DOI: 10.1002/anse.202200105

John A. Adegoke, Callum Gassner, Dr. Varun J. Sharma, Dr. Sheila K. Patel, Dr. Louise Jackett, Dr. Isaac O. Afara, Prof. Jaishankar Raman, Prof. Louise M. Burrell, Prof. Bayden R. Wood

引用次数: 0

An Efficient and Reversible Singlet Oxygen Quencher for Suppressing Photobleaching of Organic Fluorescent Dyes 一种抑制有机荧光染料光漂白的高效可逆单态氧猝灭剂

Analysis & sensing Pub Date : 2022-12-08 DOI: 10.1002/anse.202200099

Rui Jiang, En-lai Yang, Zhen-zhen Lin, Prof. Xu-dong Wang

引用次数: 0

Engineering of Interfaces with Tetrahedra DNA Nanostructures for Biosensing Applications 用于生物传感应用的四面体DNA纳米结构的界面工程

Analysis & sensing Pub Date : 2022-11-30 DOI: 10.1002/anse.202200100

Dr. Jinnan Xuan, Dr. Zhen Wang, Dr. Mingshu Xiao, Prof. Hao Pei

{"title":"Engineering of Interfaces with Tetrahedra DNA Nanostructures for Biosensing Applications","authors":"Dr. Jinnan Xuan, Dr. Zhen Wang, Dr. Mingshu Xiao, Prof. Hao Pei","doi":"10.1002/anse.202200100","DOIUrl":"https://doi.org/10.1002/anse.202200100","url":null,"abstract":"The probe-target interactions in the interfaces are significantly critical to biosensing. However, the disordered arrangement of probes and nonspecific adsorption of proteins in the biosensing interfaces for conventional biosensors often restricted the accessibility and recognition efficiency of probes towards targets, leading to poor detection performances (e. g., sensitivity and selectivity). Engineering of biosensing interfaces with functional molecules or nanomaterials has provided a promising molecular toolkit for enhanced accessibility and efficient recognition of biosensing probes. Among them, DNA has been an appealing material for interface engineering, because of its unique merits of biocompatible, predictable hybridization, and unparallel self-assembly ability. In particular, employing tetrahedra DNA nanostructures (TDNs) to engineer interfaces has been a powerful means to improve biosensor performance. Here, this review introduces the recent progress in TDN-based interface engineering. Then, we summarize the roles of TDNs in tailoring the properties of different interfaces, including electrode surface, channel surface, cell surface, etc., and highlight their biosensing applications. Finally, scientific challenges and future perspectives of TDN-engineered biosensing interface are also discussed.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50148492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0