Advances in ophthalmology practice and research最新文献

{"title":"Ocular surface heat flux density as a biomarker related to diabetic retinopathy (pilot study)","authors":"Lukyan Anatychuk, Roman Kobylianskyi, Oleg Zadorozhnyy, Taras Kustryn, Illia Nasinnyk, Andrii Korol, Nataliya Pasyechnikova","doi":"10.1016/j.aopr.2024.03.004","DOIUrl":"10.1016/j.aopr.2024.03.004","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 3","pages":"Pages 107-111"},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000222/pdfft?md5=7e188c5719d9efdc0f7049755f5dbaae&pid=1-s2.0-S2667376224000222-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140404580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of smartphone technology and artificial intelligence for advanced ophthalmic care: A systematic review","authors":"Kai Jin ,&nbsp;Yingyu Li ,&nbsp;Hongkang Wu ,&nbsp;Yih Chung Tham ,&nbsp;Victor Koh ,&nbsp;Yitian Zhao ,&nbsp;Ryo Kawasaki ,&nbsp;Andrzej Grzybowski ,&nbsp;Juan Ye","doi":"10.1016/j.aopr.2024.03.003","DOIUrl":"10.1016/j.aopr.2024.03.003","url":null,"abstract":"<div><h3>Background</h3><p>The convergence of smartphone technology and artificial intelligence (AI) has revolutionized the landscape of ophthalmic care, offering unprecedented opportunities for diagnosis, monitoring, and management of ocular conditions. Nevertheless, there is a lack of systematic studies on discussing the integration of smartphone and AI in this field.</p></div><div><h3>Main text</h3><p>This review includes 52 studies, and explores the integration of smartphones and AI in ophthalmology, delineating its collective impact on screening methodologies, disease detection, telemedicine initiatives, and patient management. The collective findings from the curated studies indicate promising performance of the smartphone-based AI screening for various ocular diseases which encompass major retinal diseases, glaucoma, cataract, visual impairment in children and ocular surface diseases. Moreover, the utilization of smartphone-based imaging modalities, coupled with AI algorithms, is able to provide timely, efficient and cost-effective screening for ocular pathologies. This modality can also facilitate patient self-monitoring, remote patient monitoring and enhancing accessibility to eye care services, particularly in underserved regions. Challenges involving data privacy, algorithm validation, regulatory frameworks and issues of trust are still need to be addressed. Furthermore, evaluation on real-world implementation is imperative as well, and real-world prospective studies are currently lacking.</p></div><div><h3>Conclusions</h3><p>Smartphone ocular imaging merged with AI enables earlier, precise diagnoses, personalized treatments, and enhanced service accessibility in eye care. Collaboration is crucial to navigate ethical and data security challenges while responsibly leveraging these innovations, promising a potential revolution in care access and global eye health equity.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 3","pages":"Pages 120-127"},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000210/pdfft?md5=15dd74fd99010c9b70eb60504d51094d&pid=1-s2.0-S2667376224000210-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of sentiment and word frequency analysis of physician review sites to evaluate refractive surgery care","authors":"Victoria Vought ,&nbsp;Rita Vought ,&nbsp;Andrew S. Lee ,&nbsp;Irene Zhou ,&nbsp;Mansi Garneni ,&nbsp;Steven A. Greenstein","doi":"10.1016/j.aopr.2024.03.002","DOIUrl":"10.1016/j.aopr.2024.03.002","url":null,"abstract":"<div><h3>Background</h3><p>Online physician reviews increase transparency in health care, helping patients make informed decisions about their provider. Language processing techniques can quantify this data and allow providers to better understand patients' experiences, perspectives, and priorities. The objective of this study was to assess patient satisfaction and understand the aspects of care that are valued by patients seeking refractive care using sentiment and word frequency analysis.</p></div><div><h3>Methods</h3><p>Written reviews and Star ratings for members of the Refractive Surgery Alliance Society practicing in the United States were collected from Healthgrades, a popular physician rating website. Surgeons with at least one written review were included in the study. Reviews were scored from -1 (most negative) to +1 (most positive) using Valence Aware Dictionary sEntiment Reasoner (VADER). Reviews were stratified by demographic characteristics, namely gender, region, and years in practice. Word frequency analysis was applied to find the most common words and phrases.</p></div><div><h3>Results</h3><p>A total of 254 specialists and 3104 reviews were analyzed, with an average of 4.4/5 stars and mean 48 ratings each. Most physicians had positive reviews (96%, average VADER ​= ​0.69). Younger physicians (&lt;20 years since residency) had significantly higher Stars rating than senior peers (&gt;20 years) (<em>P</em> ​&lt; ​0.001). A similar trend was observed in VADER score (0.71 vs 0.69), although not statistically significant (<em>P</em> ​= ​0.06). No statistical differences were observed between Stars rating and VADER score by gender (<em>P</em> ​= ​0.66, <em>P</em> ​= ​0.83) or by geographical region (<em>P</em> ​= ​0.74, <em>P</em> ​= ​0.07). \"Staff\" (n ​= ​1269), \"professional\" (n ​= ​631), \"office\" (n ​= ​523), \"questions\" (n ​= ​424), and \"friendly\" (n ​= ​386) were frequently used in reviews, along with phrases such as \"the staff\" (n ​= ​273) and \"my questions\" (n ​= ​174). \"Surgery\" (n ​= ​719), \"staff\" (n ​= ​576), \"procedure\" (n ​= ​251), \"experience\" (n ​= ​243), and \"professional\" (n ​= ​240) were the most common words in positive reviews, while \"surgery\" (n ​= ​147), \"office\" (n ​= ​86), \"staff\" (n ​= ​54), \"time\" (n ​= ​47), and \"insurance\" (n ​= ​28) were the most commonly used in negative reviews.</p></div><div><h3>Conclusions</h3><p>Both the average Stars and VADER sentiment score suggest a high satisfaction among refractive patients. Word frequency analysis revealed that patients value non-clinical aspects of care, including interactions with staff, insurance coverage, and wait-times, suggesting that improving non-clinical factors could enhance patient satisfaction with refractive surgery.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 2","pages":"Pages 78-83"},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000209/pdfft?md5=ea23a98b746597512a461225a39e3053&pid=1-s2.0-S2667376224000209-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140084149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related quality of life measurements in children and adolescents with refractive errors: A scoping review","authors":"Wei Wu ,&nbsp;Lisha Yi ,&nbsp;Kai Zhang ,&nbsp;Zipei Chen ,&nbsp;Caiping Shi ,&nbsp;Chen Chen ,&nbsp;Yilu Cai ,&nbsp;Lidan Hu ,&nbsp;Xiangjun Chen","doi":"10.1016/j.aopr.2024.03.001","DOIUrl":"10.1016/j.aopr.2024.03.001","url":null,"abstract":"<div><h3>Background</h3><p>Refractive errors, particularly myopia, are the leading visual disorders worldwide, significantly affecting the quality of life (QOL) even after correction. This scoping review focuses on health-related quality of life (HRQOL) measurements for children and adolescents with refractive errors.</p></div><div><h3>Main text</h3><p>We explored generic and disease-specific HRQOL tools, examining their content, psychometric properties, and the impact of various interventions on QOL. Two English databases—PubMed, Embase, and one Chinese database, CNKI, were searched for relevant studies published from January 2001 to October 2023. Inclusion criteria encompassed studies using standardized instruments to assess the QOL of children aged 0–18 with refractive errors. The review compares prevalent HRQOL measurements, analyzes children's refractive error assessments, and discusses intervention effects on patient QOL.</p></div><div><h3>Conclusions</h3><p>The study underlines the necessity of developing disease-specific QOL instruments for very young children and serves as a practical guide for researchers in this field. The findings advocate for a targeted approach in HRQOL assessment among the pediatric population, identifying critical gaps in current methodologies.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 2","pages":"Pages 84-94"},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000192/pdfft?md5=1487260258181248186dbd591ed76281&pid=1-s2.0-S2667376224000192-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140269867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalized treatment concepts in extraocular cancer","authors":"Sitong Ju ,&nbsp;Alexander C. Rokohl ,&nbsp;Yongwei Guo ,&nbsp;Ke Yao ,&nbsp;Wanlin Fan ,&nbsp;Ludwig M. Heindl","doi":"10.1016/j.aopr.2024.02.003","DOIUrl":"10.1016/j.aopr.2024.02.003","url":null,"abstract":"<div><h3>Background</h3><p>The periocular skin is neoplasms-prone to various benign and malignant. Periocular malignancies are more aggressive and challenging to cure and repair than those in other skin areas. In recent decades, immunotherapy has significantly advanced oncology, allowing the autoimmune system to target and destroy malignant cells. Skin malignancies, especially periocular tumors, are particularly sensitive to immunotherapy. This technique has dramatically impacted the successful treatment of challenging tumors.</p></div><div><h3>Main text</h3><p>Extraocular cancers, including eyelid (basal cell carcinoma, squamous cell carcinoma, melanoma, merkel cell carcinoma), conjunctival tumors (conjunctival melanoma, ocular surface squamous neoplasia) and other rare tumors, are unique and challenging clinical situations. Several genetic alterations associated with the pathogenesis of these diseases have been identified, and molecular mechanism are essential for the development of the immunotherapy agents, such as Hedgehog pathway inhibitors (vismodegib and sonidegib) for basal cell carcinoma, BRAF/MEK inhibitors (vemurafenib, dabrafenib, and encorafenib) for melanoma, and immune checkpoint inhibitors (Avelumab, pembrolizumab) for Merkel cell carcinoma.</p></div><div><h3>Conclusions</h3><p>The optimal treatment for periocular skin cancer depends on the type and size of the tumor and whether it involves orbital and adnexal structures. Adjuvant and neoadjuvant therapy with chemotherapy-targeted therapies and immune checkpoint inhibitors should be considered based on tumor type, tumor molecular profile, expected response rate, and candidacy for systemic treatment.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 2","pages":"Pages 69-77"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000118/pdfft?md5=edb4a670137034508a3c47340bef9273&pid=1-s2.0-S2667376224000118-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140082944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regenerative treatment of ophthalmic diseases with stem cells: Principles, progress, and challenges","authors":"Yifei Niu ,&nbsp;Junfeng Ji ,&nbsp;Ke Yao ,&nbsp;Qiuli Fu","doi":"10.1016/j.aopr.2024.02.001","DOIUrl":"https://doi.org/10.1016/j.aopr.2024.02.001","url":null,"abstract":"<div><h3>Background</h3><p>Degenerate eye disorders, such as glaucoma, cataracts and age-related macular degeneration (AMD), are prevalent causes of blindness and visual impairment worldwide. Other eye disorders, including limbal stem cell deficiency (LSCD), dry eye diseases (DED), and retinitis pigmentosa (RP), result in symptoms such as ocular discomfort and impaired visual function, significantly impacting quality of life. Traditional therapies are limited, primarily focus on delaying disease progression, while emerging stem cell therapy directly targets ocular tissues, aiming to restore ocular function by reconstructing ocular tissue.</p></div><div><h3>Main text</h3><p>The utilization of stem cells for the treatment of diverse degenerative ocular diseases is becoming increasingly significant, owing to the regenerative and malleable properties of stem cells and their functional cells. Currently, stem cell therapy for ophthalmopathy involves various cell types, such as embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), and retinal progenitor cells (RPCs). In the current article, we will review the current progress regarding the utilization of stem cells for the regeneration of ocular tissue covering key eye tissues from the cornea to the retina. These therapies aim to address the loss of functional cells, restore damaged ocular tissue and or in a paracrine-mediated manner. We also provide an overview of the ocular disorders that stem cell therapy is targeting, as well as the difficulties and opportunities in this field.</p></div><div><h3>Conclusions</h3><p>Stem cells can not only promote tissue regeneration but also release exosomes to mitigate inflammation and provide neuroprotection, making stem cell therapy emerge as a promising approach for treating a wide range of eye disorders through multiple mechanisms.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 2","pages":"Pages 52-64"},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266737622400009X/pdfft?md5=05a06b3fd055e75a8b44dbdd244049e6&pid=1-s2.0-S266737622400009X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of lens anterior capsule disc for corneal endothelium protection during femtosecond laser-assisted cataract surgery in eyes with low endothelial cell density","authors":"Nina Asrini Noor,&nbsp;Johan Hutauruk,&nbsp;Tjahjono D. Gondhowiardjo","doi":"10.1016/j.aopr.2024.02.002","DOIUrl":"https://doi.org/10.1016/j.aopr.2024.02.002","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 2","pages":"Pages 65-68"},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000106/pdfft?md5=cf04f59f1f87a91803321fe676a2309a&pid=1-s2.0-S2667376224000106-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140332463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of 3% diquafosol combined with azelastine hydrochloride in allergic conjunctivitis patients with dry eye","authors":"Lin Lin ,&nbsp;Yirui Zhu ,&nbsp;Kelan Yuan,&nbsp;Yujie Mou,&nbsp;Hanhe Zhao,&nbsp;Yayin Wu,&nbsp;Xiuming Jin","doi":"10.1016/j.aopr.2024.01.006","DOIUrl":"10.1016/j.aopr.2024.01.006","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 2","pages":"Pages 47-51"},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000064/pdfft?md5=789942a866e56ed7a429a4450875c3fb&pid=1-s2.0-S2667376224000064-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139824158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating for unrecognized deficits in perimetry associated with functional upper eyelid malposition","authors":"Linyan Wang ,&nbsp;Davin C. Ashraf ,&nbsp;Michael Deiner ,&nbsp;Oluwatobi O. Idowu ,&nbsp;Seanna R. Grob ,&nbsp;Bryan J. Winn ,&nbsp;M Reza Vagefi ,&nbsp;Robert C. Kersten","doi":"10.1016/j.aopr.2024.01.007","DOIUrl":"10.1016/j.aopr.2024.01.007","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate whether functional upper eyelid malposition is associated with unrecognized deficits in automated perimetry among glaucoma patients by examining patients undergoing eyelid surgery who had not been identified as requiring eyelid taping during glaucoma field testing.</p></div><div><h3>Methods</h3><p>In this retrospective pre-post study, an automated database search followed by manual chart review was used to identify eligible patients from January 2012 to March 2020. Included patients had reliable visual field testing within two years before and after functional upper blepharoplasty or ptosis repair and no comorbid ocular diagnoses. As part of routine practice, glaucoma visual field technicians taped patients with pupil-obstructing eyelid malposition; taped examinations were excluded from analysis. Clinical and demographic characteristics, mean deviation, and pattern standard deviation were evaluated within a two year period before and after eyelid surgery.</p></div><div><h3>Results</h3><p>The final analysis included 60 eyes of 38 patients. Change in visual field parameters after eyelid surgery did not reach statistical significance in crude or adjusted analyses. Among patients with ptosis, the margin reflex distance-1 was not associated with change in mean deviation after surgery (Pearson R² ​= ​0.0061; <em>P</em> ​= ​0.700). Five of 17 eyes excluded from analysis due to unreliable pre-operative visual fields demonstrated substantial improvement after surgery.</p></div><div><h3>Conclusions</h3><p>Functional upper eyelid malposition does not appear to cause spurious visual field abnormalities among glaucoma patients with reliable visual fields who were determined not to require eyelid taping at the time of their visual fields. Unreliable visual fields could be a sign of eyelid interference in this population.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 1","pages":"Pages 39-44"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000076/pdfft?md5=7d65e214918326babd8fa3dfa141f722&pid=1-s2.0-S2667376224000076-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139815843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of 3% diquafosol combined with azelastine hydrochloride in allergic conjunctivitis patients with dry eye","authors":"Lin Lin, Yirui Zhu, Kelan Yuan, Yujie Mou, Hanhe Zhao, Yaying Wu, Xiuming Jin","doi":"10.1016/j.aopr.2024.01.006","DOIUrl":"https://doi.org/10.1016/j.aopr.2024.01.006","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"24 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139883915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}