Advances in ophthalmology practice and research最新文献

{"title":"A two-year longitudinal observational study of the peripapillary microvasculature in pediatric type 1 diabetes mellitus patients without visual impairment or diabetic retinopathy","authors":"Lipu Cui, Chenhao Yang, Haidong Zou","doi":"10.1016/j.aopr.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.aopr.2024.01.001","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 1","pages":"Pages 15-22"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000015/pdfft?md5=a4001c50e3181f3eeb005e686e4b871e&pid=1-s2.0-S2667376224000015-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139674617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TOC","authors":"","doi":"10.1016/S2667-3762(24)00015-5","DOIUrl":"https://doi.org/10.1016/S2667-3762(24)00015-5","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 1","pages":"Pages iii-iv"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000155/pdfft?md5=fb30c91080e2dbba6039c1f7cd1f093b&pid=1-s2.0-S2667376224000155-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140163776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to letter to the editor regarding \"Is relying on RNFL specific enough to identify any changes in the CNS?\"","authors":"Hanfei Wu , Haishuang Lin , Mengting Ruan, Huanjie Fang, Nannan Dong, Tiewei Wang, Feifei Yu, Jiawei Zhao","doi":"10.1016/j.aopr.2024.01.003","DOIUrl":"10.1016/j.aopr.2024.01.003","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 1","pages":"Page 45"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000039/pdfft?md5=872602d7517fc9cdf6766598481ffda6&pid=1-s2.0-S2667376224000039-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139817368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent progress of nanomedicine in managing dry eye disease","authors":"Zeen Lv ,&nbsp;Su Li ,&nbsp;Guixiang Zeng ,&nbsp;Ke Yao ,&nbsp;Haijie Han","doi":"10.1016/j.aopr.2024.01.008","DOIUrl":"https://doi.org/10.1016/j.aopr.2024.01.008","url":null,"abstract":"<div><h3>Background</h3><p>Dry eye disease (DED) is a commonly reported ocular complaint that has garnered significant attention in recent research. The global occurrence of DED ranges from 5% to 50%, impacting a substantial proportion of individuals worldwide with increasing frequency. Although topical administration remains the mainstream drug delivery method for ocular diseases, it suffers from drawbacks such as low bioavailability, rapid drug metabolism, and frequent administration requirements. Fortunately, the advancements in nanomedicine offer effective solutions to address the aforementioned issues and provide significant assistance in the treatment of DED.</p></div><div><h3>Main text</h3><p>DED is considered a multifactorial disease of the ocular surface and tear film, in which the integrity of tear film function and structure plays a crucial role in maintaining the homeostasis of the ocular surface. The conventional treatment for DED involves the utilization of artificial tear products, cyclosporin, corticosteroids, mucin secretagogues, and nonsteroidal anti-inflammatory drugs. Furthermore, nanomedicine is presently a significant field of study, with numerous clinical trials underway for various nanotherapeutics including nanoemulsions, nanosuspensions, liposomes, and micelles. Notably, some of these innovative nanoformulations have already received FDA approval as novel remedies for DED, and the advancement of nanomedicine is poised to offer enhanced prospects to solve the shortcomings of existing treatments for DED partially.</p></div><div><h3>Conclusions</h3><p>This article provides an overview of the latest advancements in nanomedicine for DED treatment, while the field of DED treatment is expected to witness a remarkable breakthrough shortly with the development of nanomedicine, bringing promising prospects for patients worldwide suffering conditions.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 1","pages":"Pages 23-31"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000088/pdfft?md5=ebc5ca87a18661140e0772d47574d08c&pid=1-s2.0-S2667376224000088-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139709483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the letter to the editor regarding “Is relying on RNFL specific enough to identify any changes in the CNS?”","authors":"Hanfei Wu, Haishuang Lin, Mengting Ruan, Huanjie Fang, Nannan Dong, Tiewei Wang, Feifei Yu, Jiawei Zhao","doi":"10.1016/j.aopr.2024.01.003","DOIUrl":"https://doi.org/10.1016/j.aopr.2024.01.003","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"318 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139876943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating for unrecognized deficits in perimetry associated with functional upper eyelid malposition","authors":"Linyan Wang, Davin C. Ashraf, Michael Deiner, Oluwatobi O. Idowu, Seanna R. Grob, Bryan J. Winn, M. Vagefi, Robert C. Kersten","doi":"10.1016/j.aopr.2024.01.007","DOIUrl":"https://doi.org/10.1016/j.aopr.2024.01.007","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"37 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139875623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crossover to PDT after the unsuccessful micropulse laser treatment of central serous chorioretinopathy","authors":"Maciej Gawęcki ,&nbsp;Krzysztof Kiciński ,&nbsp;Andrzej Grzybowski","doi":"10.1016/j.aopr.2024.01.004","DOIUrl":"10.1016/j.aopr.2024.01.004","url":null,"abstract":"<div><h3>Purpose</h3><p>Subthreshold micropulse laser (SML) and photodynamic therapy (PDT) are among the most effective therapeutic modalities applied to central serous chorioretinopathy (CSCR). This study aimed to evaluate the efficacy and durability of PDT in CSCR cases unresponsive to at least two SML treatments.</p></div><div><h3>Methods</h3><p>The study included 26 consecutive eyes of 24 patients (21 males and three females) with chronic CSCR. In all cases, a lack of reduction in subretinal fluid (SRF) levels was noted after at least two consecutive SML sessions. The parameters of best corrected visual acuity (BCVA) and spectral domain optical coherence tomography (SD-OCT) were evaluated at baseline and 1, 3 and 12 months post-PDT.</p></div><div><h3>Results</h3><p>The mean duration of symptoms in the group was 53.81 ± 39.48 months, the mean age of the patients was 49.26 ± 12.91 years, and the mean subfoveal choroidal thickness (SFCT) was 572.11 ± 116.21 mm. Complete resorption of SRF was observed in 21 out of 26 eyes (80.77%) at 1 month and sustained in 18 cases (69.23%) at 12 months. At 12 months, in the sustained group, BCVA improved significantly from 0.39 ± 0.18 to 0.19 ± 0.2 logMAR (<em>P</em> = 0.01), central subfoveal thickness (CST) reduced from 316.44 ± 75.83 mm to 197.67 ± 22.99 mm (<em>P</em> &lt; 0.0001), and SFCT reduced from 579.28 mm to 446.78 mm (<em>P</em> &lt; 0.0001).</p></div><div><h3>Conclusions</h3><p>PDT provides the opportunity for the successful treatment of CSCR unresponsive to SML treatment. Improvements are possible even in cases with a long duration of symptoms and significant alterations in retinal morphology. Thus, PDT should be considered for patients with prominently increased choroidal thickness.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 1","pages":"Pages 32-38"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000040/pdfft?md5=d6e2139d9e4970a2e57c228e7f858403&pid=1-s2.0-S2667376224000040-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139631916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An assessment of the capability of ChatGPT in solving clinical cases of ophthalmology using multiple choice and short answer questions","authors":"Anjana Christy Alexander ,&nbsp;Suprithy Somineni Raghupathy ,&nbsp;Krishna Mohan Surapaneni","doi":"10.1016/j.aopr.2024.01.005","DOIUrl":"10.1016/j.aopr.2024.01.005","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 2","pages":"Pages 95-97"},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000052/pdfft?md5=3fa32df33d56f6d9d31df34c8dfad573&pid=1-s2.0-S2667376224000052-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139540598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is relying on RNFL specific enough to identify any changes in the CNS?","authors":"Dzakky Avecienna Nur Faridwazdi,&nbsp;Yuliono Trika Nur Hasan,&nbsp;Alvi Milliana,&nbsp;Zulvikar Syambani Ulhaq","doi":"10.1016/j.aopr.2024.01.002","DOIUrl":"10.1016/j.aopr.2024.01.002","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 1","pages":"Page 14"},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000027/pdfft?md5=b36fc940ee3dd5e8150aa5191371b407&pid=1-s2.0-S2667376224000027-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139539917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of choroidal thickness and retinal nerve fiber layer thickness in Chinese pregnant women and healthy non-pregnant women","authors":"Hanfei Wu ,&nbsp;Haishuang Lin ,&nbsp;Mengting Ruan ,&nbsp;Huanjie Fang ,&nbsp;Nannan Dong ,&nbsp;Tiewei Wang ,&nbsp;Feifei Yu ,&nbsp;Jiawei Zhao","doi":"10.1016/j.aopr.2023.12.001","DOIUrl":"10.1016/j.aopr.2023.12.001","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate choroidal thickness and retinal nerve fiber layer (RNFL) thickness in different trimesters using enhanced depth imaging optical coherence tomography (EDI-OCT).</p></div><div><h3>Methods</h3><p>A prospective comparative study included 45 healthy pregnant women in the first trimester, 45 women in the second, 45 women in the third and 45 healthy non-pregnant women as the control group. Macular choroidal thickness was measured at three locations: The subfoveal, 1 ​mm temporal, and 1 ​mm nasal from the fovea with EDI-OCT. Peripapillary choroidal thickness (PPCT) and RNFL thickness parameters were automatically calculated by the Spectralis OCT.</p></div><div><h3>Results</h3><p>The subfoveal, temporal and nasal macular choroidal thickness were all significantly thicker in the second trimester, compared with those parameters in the first, the third trimesters and the control group (all <em>P</em> ​&lt; ​0.05). The PPCT was significantly increased in the second trimeter compared with the control group at global, temporal, temporal inferior, nasal and nasal inferior positions (all <em>P</em> ​&lt; ​0.05). The RNFL thickness was also significantly increased in pregnant women at nasal superior and nasal inferior quadrants (all <em>P</em> ​&lt; ​0.05).</p></div><div><h3>Conclusions</h3><p>The choroidal thickness in pregnant women was found to be thicker than the control group, regardless of macular or optic disc location. Findings of RNFL thickening might indicate subclinical involvement of the central nervous system.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 1","pages":"Pages 8-13"},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376223000628/pdfft?md5=e1acd14582585864316213ce1a25fe6e&pid=1-s2.0-S2667376223000628-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138625448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}