Actas urologicas espanolas最新文献_第6页

Optimización de la triple terapia en el tratamiento del cáncer de próstata hormonosensible metastásico 优化激素敏感转移性前列腺癌的三联疗法

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-12-01 DOI: 10.1016/j.acuro.2024.07.003

A. Borque-Fernando , D.A. Pérez-Fentes , M. Rodrigo-Aliaga , J. Puente-Vázquez , A. Gómez-Iturriaga , M. Unda , M.A. Calleja-Hernández , J.M. Cózar-Olmo , J.L. Álvarez-Ossorio

{"title":"Optimización de la triple terapia en el tratamiento del cáncer de próstata hormonosensible metastásico","authors":"A. Borque-Fernando , D.A. Pérez-Fentes , M. Rodrigo-Aliaga , J. Puente-Vázquez , A. Gómez-Iturriaga , M. Unda , M.A. Calleja-Hernández , J.M. Cózar-Olmo , J.L. Álvarez-Ossorio","doi":"10.1016/j.acuro.2024.07.003","DOIUrl":"10.1016/j.acuro.2024.07.003","url":null,"abstract":"<div><div>Triple therapy with docetaxel, androgen deprivation therapy (ADT) and androgen receptor pathway inhibitors (ARPIs) has demonstrated survival benefits in patients with metastatic hormone-sensitive prostate cancer (mHSPC), especially in those with high-risk disease. However, once the use of ADT and docetaxel is established, guidelines do not clearly specify which ARPI is most appropriate. In this work, a literature review to identify phase III clinical trials, systematic reviews, meta-analyses, and clinical practice guidelines on triple therapy in mHSPC was carried out. Evidence and recommendations were qualitatively reviewed to provide guidelines on the most suitable ARPI based on patient risk, disease volume, and nature of metastases (synchronous or metachronous). This review aims to update the previously published consensus on the optimal pharmacological treatment for mHSPC and to expose the opinions of hospital pharmacy, urology and medical and radiation oncology experts.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 10","pages":"Pages 703-717"},"PeriodicalIF":1.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hacia un cambio de modelo en el manejo de la hiperplasia benigna de próstata: importancia de un enfoque individualizado 改变良性前列腺增生管理模式：个体化方法的重要性

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-12-01 DOI: 10.1016/j.acuro.2024.09.001

A. Alcántara Montero

引用次数: 0

Evaluación de los cambios en la función sexual en pacientes sometidos a cirugía endoscópica de la litiasis del tracto urinario superior 评价上尿路碎石症内镜手术患者的性功能变化

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-12-01 DOI: 10.1016/j.acuro.2024.06.002

J. Tabares Jiménez, G. Bueno Serrano, M.P. Alcoba García, R. González López, B. Gómez Jordana, I. Mahillo Fernández, C. González Enguita

{"title":"Evaluación de los cambios en la función sexual en pacientes sometidos a cirugía endoscópica de la litiasis del tracto urinario superior","authors":"J. Tabares Jiménez, G. Bueno Serrano, M.P. Alcoba García, R. González López, B. Gómez Jordana, I. Mahillo Fernández, C. González Enguita","doi":"10.1016/j.acuro.2024.06.002","DOIUrl":"10.1016/j.acuro.2024.06.002","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the effect of endoscopic surgery on sexual function in patients with upper urinary tract (UUT) lithiasis.</div></div><div><h3>Material and methods</h3><div>We conducted an observational, prospective, longitudinal study with a single cohort of cases undergoing ureteroscopy (URS), retrograde intrarenal surgery (RIRS), or endoscopic combined intrarenal surgery (ECIRS). Patients’ sexual response was assessed with questionnaires in the 30 days prior to surgery, and at one and three months after surgery. The International Index of Erectile Function (IIEF-t) was used in male patients, and the Female Sexual Function Index (FSFI) was used in female patients.</div></div><div><h3>Results</h3><div>Seventy patients -34 men and 36 women- completed the study. Among men, the IIEF-t did not show significant difference between baseline scores (64.1±7.50) and those obtained at 3 months (63.8±9.51), with a non-significant decrease (p=0.054) at the first month (61.4±10.4). Subdomains did not worsen at 3 months, and desire (IIEF-SD) improved from 7.3±1.9 to 8.0±1.8. Among women, the FSFI-t did not change significantly after surgery: baseline score (27.3±4.1), 1-month score (26.8±3.7) and 3-month score (27.5±4.2). No subdomain worsened at the third month.</div></div><div><h3>Conclusion</h3><div>Endoscopic surgery for UUT is a safe technique in both sexes with no negative effect on sexual function. There are no differences between the baseline IIEF-t and FSFI-t scores and those obtained at 3 months.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 10","pages":"Pages 688-694"},"PeriodicalIF":1.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

El leaking pipeline y las brechas de género en Urología 泌尿外科的泄漏管道和性别差距

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-12-01 DOI: 10.1016/j.acuro.2024.05.001

A. Medina Gamero

引用次数: 0

Hacia el cribado poblacional del cáncer de próstata en España 向西班牙前列腺癌筛查人群迈进

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-12-01 DOI: 10.1016/j.acuro.2024.10.001

J. Morote Robles

引用次数: 0

Aplicación clínica del sistema de liberación uretral UroLift® en España: consenso sobre el tratamiento de los síntomas del tracto urinario inferior asociados a la obstrucción del flujo urinario por hiperplasia benigna de próstata UroLift®尿路释放系统在西班牙的临床应用：关于治疗良性前列腺增生导致尿流阻塞的下尿路症状的共识

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-12-01 DOI: 10.1016/j.acuro.2024.06.003

M. Fernández Arjona , L. López Martín , L.M. Herranz Fernández , B. Sinues Ojas , J.M. Campá Bortoló , J. Extramiana Cameno , E. López Alcina , I. Povo Martín , A. Budía Alba , G. Ordaz Jurado , J.M. Osca García , M. Perán Teruel , V. Gimeno Argente , A. Navarro Beltrán , J. Benejam Gual , Y.E. Hernández Martínez , C. González Enguita

{"title":"Aplicación clínica del sistema de liberación uretral UroLift® en España: consenso sobre el tratamiento de los síntomas del tracto urinario inferior asociados a la obstrucción del flujo urinario por hiperplasia benigna de próstata","authors":"M. Fernández Arjona , L. López Martín , L.M. Herranz Fernández , B. Sinues Ojas , J.M. Campá Bortoló , J. Extramiana Cameno , E. López Alcina , I. Povo Martín , A. Budía Alba , G. Ordaz Jurado , J.M. Osca García , M. Perán Teruel , V. Gimeno Argente , A. Navarro Beltrán , J. Benejam Gual , Y.E. Hernández Martínez , C. González Enguita","doi":"10.1016/j.acuro.2024.06.003","DOIUrl":"10.1016/j.acuro.2024.06.003","url":null,"abstract":"<div><div>Benign prostatic hyperplasia is an increasingly common pathology in the adult male, especially after the age of 40-45 years, and its management consumes an enormous amount of resources. The UroLift® system is an approved technology designed to treat lower urinary tract symptoms secondary to benign prostatic hyperplasia and is used to perform the prostatic urethral lift procedure. Various urology specialists in Spain with experience in prostatic urethral lift have prepared this consensus document. Endorsed by the Spanish Urology Association, its information is based on the most recent findings. The main objective of this document is to disseminate the consensus recommendations among all professionals treating patients with lower urinary tract symptoms/benign prostatic hyperplasia. Both primary care physicians and urologists can assess and offer prostatic urethral lift as an effective, minimally invasive treatment.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 10","pages":"Pages 732-738"},"PeriodicalIF":1.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Documento de consenso sobre las implicaciones de la normalización del suministro del Bacillus Calmette-Guérin en el manejo del paciente con tumor vesical no-músculo invasivo (TVNMI) 关于标准化提供Calmette- Guerin芽孢杆菌对侵袭性非肌肉膀胱肿瘤（TVNMI）患者管理的影响的共识文件

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-12-01 DOI: 10.1016/j.acuro.2024.06.004

Ó. Rodríguez Faba , J.M. Fernández Gómez , F. Guerrero-Ramos , M. Álvarez-Maestro , M.J. Ledo Cepero , M. Unda Urzaiz , L. Martínez-Piñeiro , J.M. Cózar Olmo , J. Palou Redorta , J.L. Álvarez-Ossorio

{"title":"Documento de consenso sobre las implicaciones de la normalización del suministro del Bacillus Calmette-Guérin en el manejo del paciente con tumor vesical no-músculo invasivo (TVNMI)","authors":"Ó. Rodríguez Faba , J.M. Fernández Gómez , F. Guerrero-Ramos , M. Álvarez-Maestro , M.J. Ledo Cepero , M. Unda Urzaiz , L. Martínez-Piñeiro , J.M. Cózar Olmo , J. Palou Redorta , J.L. Álvarez-Ossorio","doi":"10.1016/j.acuro.2024.06.004","DOIUrl":"10.1016/j.acuro.2024.06.004","url":null,"abstract":"<div><div>Patients with non-muscle-invasive bladder cancer (NMIBC) in the intermediate and high-risk groups must receive adjuvant treatment with intravesical Bacillus Calmette-Guerin (BCG) following transurethral resection (TUR), as it reduces the risk of recurrence and presumably the risk of progression as well. Optimization of BCG efficacy is achieved by administering maintenance therapy. However, since many immunological aspects of the mechanism of action of BCG in the bladder remain unknown, the implementation of the optimal dose, number of instillations, strains and adequate maintenance regimen over the last decades has been heterogeneous. Additionally, this has hindered the interpretation of efficacy in terms of oncologic outcomes. This, together with the shortages of BCG in recent years, have forced scientific societies to adapt their clinical practice guidelines and modify their protocols of adjuvant treatment with BCG. This includes changes to strains, doses, and maintenance during this period of time. This consensus document evaluates the current status of adjuvant BCG treatment and the implications of BCG supply availability in the treatment of patients with NMIBC. It also addresses the implementation of novel therapies that will improve cancer prognosis and the quality of life of patients with NMIBC in the future.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 10","pages":"Pages 718-731"},"PeriodicalIF":1.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Producción científica en urología: un análisis bibliométrico de 20 años en Latinoamérica 泌尿学的科学生产：拉丁美洲20年文献计量分析

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-12-01 DOI: 10.1016/j.acuro.2024.07.001

G. Mendoza-Chuctaya , K. Ramos-Chuctaya , P. Mendoza-Arana , E. Rios-Cadenillas

{"title":"Producción científica en urología: un análisis bibliométrico de 20 años en Latinoamérica","authors":"G. Mendoza-Chuctaya , K. Ramos-Chuctaya , P. Mendoza-Arana , E. Rios-Cadenillas","doi":"10.1016/j.acuro.2024.07.001","DOIUrl":"10.1016/j.acuro.2024.07.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The knowledge generated by scientific research is linked to the development of countries, as it provides the necessary resources to guarantee scientific progress and cost-effective healthcare. For this reason, our study analyzes the trends of scientific publication in urology in Latin America.</div></div><div><h3>Methods</h3><div>A bibliometric analysis was performed. Data collection was carried out using the SCOPUS search engine in April 2023, and the search terms were defined by the authors, including the most common diseases in the specialty of urology. A descriptive analysis of the different characteristics, trends and scientific collaborations was performed. The collaboration networks were plotted using VOSviewer.</div></div><div><h3>Results</h3><div>From 2000 to 2021, Latin American publications in urology amounted to 9135 in scientific journals. Brazil is the country with the greatest scientific production (51.2%) and Chile has the greatest scientific production per million inhabitants. Of the total number of scientific publications, 51.1% were related to prostate cancer, 88.8% were written in English (and 50.2% had non-open access). The country with greatest collaborative research with Latin America was the United States.</div></div><div><h3>Conclusions</h3><div>Scientific output in urology in Latin America has increased substantially over the last 20years. The most published topic is prostate cancer, most papers are written in English, and the United States takes first place regarding scientific collaboration. However, the proportion of the world's science originated in Latin America is still low and depends on Brazil.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 10","pages":"Pages 695-702"},"PeriodicalIF":1.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cáncer testicular en Iberoamérica: estrategias para una adecuada prevención y diagnóstico 伊比利亚美洲的睾丸癌：适当预防和诊断的战略

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-11-01 DOI: 10.1016/j.acuro.2024.05.004

引用次数: 0

Calidad de vida en pacientes intervenidas quirúrgicamente mediante malla transobturadora para la corrección de incontinencia urinaria de esfuerzo 接受经尿道网片手术矫正压力性尿失禁（SUI）患者的生活质量

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-11-01 DOI: 10.1016/j.acuro.2024.05.003

{"title":"Calidad de vida en pacientes intervenidas quirúrgicamente mediante malla transobturadora para la corrección de incontinencia urinaria de esfuerzo","authors":"","doi":"10.1016/j.acuro.2024.05.003","DOIUrl":"10.1016/j.acuro.2024.05.003","url":null,"abstract":"<div><h3>Objective</h3><div>This descriptive study examines quality of life in women undergoing placement of a midurethral sling for stress urinary incontinence.</div></div><div><h3>Material and methods</h3><div>This was a retrospective cohort study based on data from 51 women consecutively undergoing this procedure at a tertiary hospital in the years 2014 and 2015. The main outcome variable was quality of life assessed through the Sandvick severity test and International Consultation on Incontinence Short Form quality of life questionnaire (ICIQ-UI-SF) at the time points baseline or presurgery, and 6 months and 5 years postsurgery. Factors associated with treatment failure were determined through binary logistic regression.</div></div><div><h3>Results</h3><div>At 5-year follow-up we obtained an absolute reduction of 8.78 points (95% CI 6.43-11.14; p<0.001) in the ICIQ-UI-SF and 4.54 (95% CI 3.25-5.83; p<0.001) in the Sandvick severity test score, compared to baseline, in the 35 patients that completed follow-up. Out of the 51 patients that were followed, the rate of success in incontinence correction was 86.3% (44/50) with a failure rate of 12% (6/50). Multiparity and previous gynaecological surgery were identified as predisposing factors for treatment failure. Obesity was associated with a worse treatment outcome.</div></div><div><h3>Conclusion</h3><div>Sling treatment for incontinence was successful in 86.3% (44/50) of participants and remained effective 5 years after surgery in terms of quality of life.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 9","pages":"Pages 651-657"},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141277507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0