P. Izquierdo , J. Huguet , A. Bravo-Balado , S. Fontanet , A. Farré , R. Sánchez , J.M. Gaya , Ó. Rodríguez-Faba , J. Palou , A. Breda
{"title":"对85岁或85岁以上患者进行肾肿瘤腹腔镜手术","authors":"P. Izquierdo , J. Huguet , A. Bravo-Balado , S. Fontanet , A. Farré , R. Sánchez , J.M. Gaya , Ó. Rodríguez-Faba , J. Palou , A. Breda","doi":"10.1016/j.acuro.2025.501688","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To analyze our series of radical nephrectomies and laparoscopic nephroureterectomies in elderly patients.</div></div><div><h3>Materials and methods</h3><div>A retrospective review of patients aged 85 years and older who underwent major laparoscopic surgery for renal tumors at our center between April 2005 and March 2022 was conducted. Clinical-pathological characteristics, complications, and postoperative outcomes were analyzed.</div></div><div><h3>Results</h3><div>Forty-seven patients were included, with a median age of 87 years. Fifteen nephrectomies for renal tumors (Group 1), and 32 nephroureterectomies for urinary tract tumors (Group 2) were performed. In Group 1, 4<!--> <!-->postoperative complications were observed: 2<!--> <!-->Clavien 1, one Clavien 2, and one Clavien 4a. The most common histology was clear cell carcinoma; 9 patients had locally advanced tumors (TNM<!--> <!-->≥<!--> <!-->T3) at diagnosis. Five-year cancer-specific survival and overall survival rates were 73% and 40%, respectively. In Group 2, 14 postoperative complications occurred: 6<!--> <!-->(18.8%) Clavien 1, 4<!--> <!-->(12.5%) Clavien 2, and 5<!--> <!-->(15.6%) Clavien 5. All patients had urothelial carcinoma in their pathology reports. Twenty (62.5%) had invasive tumors (TNM<!--> <!-->≥<!--> <!-->T2) at diagnosis. Five-year cancer-specific survival and overall survival rates were 45% and 30%, respectively.</div></div><div><h3>Conclusion</h3><div>Laparoscopic renal oncologic surgery in elderly patients is feasible, although it is associated with a high morbimortality rate, particularly in those with urinary tract tumors. It is essential to provide this patient group with adequate information regarding the elevated surgical risks associated with the procedure.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"49 4","pages":"Article 501688"},"PeriodicalIF":1.2000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cirugía laparoscópica oncológica renal en pacientes de 85 años o mayor edad\",\"authors\":\"P. Izquierdo , J. Huguet , A. Bravo-Balado , S. Fontanet , A. Farré , R. Sánchez , J.M. Gaya , Ó. Rodríguez-Faba , J. Palou , A. Breda\",\"doi\":\"10.1016/j.acuro.2025.501688\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>To analyze our series of radical nephrectomies and laparoscopic nephroureterectomies in elderly patients.</div></div><div><h3>Materials and methods</h3><div>A retrospective review of patients aged 85 years and older who underwent major laparoscopic surgery for renal tumors at our center between April 2005 and March 2022 was conducted. Clinical-pathological characteristics, complications, and postoperative outcomes were analyzed.</div></div><div><h3>Results</h3><div>Forty-seven patients were included, with a median age of 87 years. Fifteen nephrectomies for renal tumors (Group 1), and 32 nephroureterectomies for urinary tract tumors (Group 2) were performed. In Group 1, 4<!--> <!-->postoperative complications were observed: 2<!--> <!-->Clavien 1, one Clavien 2, and one Clavien 4a. The most common histology was clear cell carcinoma; 9 patients had locally advanced tumors (TNM<!--> <!-->≥<!--> <!-->T3) at diagnosis. Five-year cancer-specific survival and overall survival rates were 73% and 40%, respectively. In Group 2, 14 postoperative complications occurred: 6<!--> <!-->(18.8%) Clavien 1, 4<!--> <!-->(12.5%) Clavien 2, and 5<!--> <!-->(15.6%) Clavien 5. All patients had urothelial carcinoma in their pathology reports. Twenty (62.5%) had invasive tumors (TNM<!--> <!-->≥<!--> <!-->T2) at diagnosis. Five-year cancer-specific survival and overall survival rates were 45% and 30%, respectively.</div></div><div><h3>Conclusion</h3><div>Laparoscopic renal oncologic surgery in elderly patients is feasible, although it is associated with a high morbimortality rate, particularly in those with urinary tract tumors. It is essential to provide this patient group with adequate information regarding the elevated surgical risks associated with the procedure.</div></div>\",\"PeriodicalId\":7145,\"journal\":{\"name\":\"Actas urologicas espanolas\",\"volume\":\"49 4\",\"pages\":\"Article 501688\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Actas urologicas espanolas\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0210480625000063\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Actas urologicas espanolas","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0210480625000063","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Cirugía laparoscópica oncológica renal en pacientes de 85 años o mayor edad
Objective
To analyze our series of radical nephrectomies and laparoscopic nephroureterectomies in elderly patients.
Materials and methods
A retrospective review of patients aged 85 years and older who underwent major laparoscopic surgery for renal tumors at our center between April 2005 and March 2022 was conducted. Clinical-pathological characteristics, complications, and postoperative outcomes were analyzed.
Results
Forty-seven patients were included, with a median age of 87 years. Fifteen nephrectomies for renal tumors (Group 1), and 32 nephroureterectomies for urinary tract tumors (Group 2) were performed. In Group 1, 4 postoperative complications were observed: 2 Clavien 1, one Clavien 2, and one Clavien 4a. The most common histology was clear cell carcinoma; 9 patients had locally advanced tumors (TNM ≥ T3) at diagnosis. Five-year cancer-specific survival and overall survival rates were 73% and 40%, respectively. In Group 2, 14 postoperative complications occurred: 6 (18.8%) Clavien 1, 4 (12.5%) Clavien 2, and 5 (15.6%) Clavien 5. All patients had urothelial carcinoma in their pathology reports. Twenty (62.5%) had invasive tumors (TNM ≥ T2) at diagnosis. Five-year cancer-specific survival and overall survival rates were 45% and 30%, respectively.
Conclusion
Laparoscopic renal oncologic surgery in elderly patients is feasible, although it is associated with a high morbimortality rate, particularly in those with urinary tract tumors. It is essential to provide this patient group with adequate information regarding the elevated surgical risks associated with the procedure.
期刊介绍:
Actas Urológicas Españolas is an international journal dedicated to urological diseases and renal transplant. It has been the official publication of the Spanish Urology Association since 1974 and of the American Urology Confederation since 2008. Its articles cover all aspects related to urology.
Actas Urológicas Españolas, governed by the peer review system (double blinded), is published online in Spanish and English. Consequently, manuscripts may be sent in Spanish or English and bidirectional free cost translation will be provided.