Actas urologicas espanolas最新文献

{"title":"Consenso multidisciplinar sobre la mejora del proceso asistencial en la vejiga hiperactiva desde la adherencia: consenso claVHes","authors":"A. Casteig Blanco,&nbsp;M. Merino,&nbsp;A. Cornet Cortada,&nbsp;grupo claVHes","doi":"10.1016/j.acuro.2026.502008","DOIUrl":"10.1016/j.acuro.2026.502008","url":null,"abstract":"<div><div>Overactive bladder management within the Spanish healthcare system faces significant challenges, including suboptimal therapeutic adherence. This consensus proposes recommendations to improve the care process (both clinical and organizational) from an adherence perspective. A Multidisciplinary Working Group of 14 members critically reviewed and discussed the literature (individually and in joint sessions) and formulated recommendations around five pillars: (1) strategic planning, with a realistic medium-term horizon and progress toward common protocols; (2) technological innovation and digitalization, enabling bidirectional communication among professionals, follow-up, clinical decision-making, and interoperability; (3) coordination and collaboration, across levels of care, healthcare professionals, and patients; (4) a focus on health outcomes and quality of life, with personalized treatments and continuous monitoring; and (5) social awareness and patient empowerment, increasing disease visibility, raising awareness among the public and patients, and fostering active patient participation.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 502008"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cambios morfométricos en la estructura del suelo pélvico tras rehabilitación no invasiva y neuromodulación mediante ecografía","authors":"S. Maiti Bera,&nbsp;P. Palma,&nbsp;J.M. Santos Flores,&nbsp;E.P. Rodríguez Vidales","doi":"10.1016/j.acuro.2026.501998","DOIUrl":"10.1016/j.acuro.2026.501998","url":null,"abstract":"<div><h3>Introduction and objective</h3><div>Pelvic floor disorders represent a common problem in female urology practice and significantly affect quality of life. Objective evidence regarding structural changes induced by non-invasive neuromodulation remains limited. The aim of this study was to evaluate, using pelvic floor ultrasound (PFUS), the morphometric changes occurring in the pelvic floor following neuromodulation with high intensity focused electromagnetic energy (HIFEM).</div></div><div><h3>Materials and methods</h3><div>This was an analytical, quasi-experimental, prospective observational study with pre- and post-intervention assessment. The study included women with pelvic floor dysfunction treated with transperineal neuromodulation using HIFEM. Urinary symptoms, quality of life, and morphometric parameters were assessed using PFUS.</div></div><div><h3>Results</h3><div>Forty-six women with a mean age of 60.4<!--> <!-->±<!--> <!-->12.6 years were analyzed. Significant improvements were observed in urinary frequency, ICIQ-SF, ICIQ-OAB, Sandvik Severity Index, and King's Health Questionnaire scores (p &lt;<!--> <!-->0.001). Ultrasound findings demonstrated reduced detrusor thickness, improved bladder emptying, enhanced pelvic floor dynamic activity, and improved pelvic support.</div></div><div><h3>Conclusions</h3><div>HIFEM neuromodulation was associated with improvements in clinical outcomes and quality of life, as well as morphometric changes in the pelvic floor objectively demonstrated by transperineal ultrasound.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 501998"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dolor esperado frente a dolor experimentado durante la cistoscopia flexible ambulatoria: un estudio prospectivo","authors":"A. Golbasi,&nbsp;E. Kızılay,&nbsp;A.Y. Ozercan,&nbsp;B. Elmaagac,&nbsp;H. Bicer,&nbsp;S. Tozan,&nbsp;M.A. Karadag","doi":"10.1016/j.acuro.2026.502032","DOIUrl":"10.1016/j.acuro.2026.502032","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>This study prospectively evaluated the relationship between pre-procedural pain expectations and experienced pain during first-time office-based cystoscopy, and assessed whether the discrepancy between them is influenced by age and gender in an outpatient tertiary care setting.</div></div><div><h3>Materials and methods</h3><div>This prospective study included adults undergoing first-time office-based cystoscopy between January and April 2026, excluding those with prior cystoscopy or chronic pain requiring analgesics/anxiolytics. All procedures were performed by a single urologist using a 16-Fr flexible cystoscope with intraurethral lidocaine. Expected and experienced pain were assessed using a 0-10 numerical rating scale and analyzed by age and gender, with p<!--> <!-->&lt;<!--> <!-->0.05 considered significant.</div></div><div><h3>Results</h3><div>A total of 117 patients (83 males, 34 females; mean age 57.6<!--> <!-->±<!--> <!-->11.7 years) were included. Post-procedural pain scores were significantly lower than pre-procedural expectations in both male and female patients (all p<!--> <!-->&lt;<!--> <!-->0.001). The magnitude of pain reduction did not differ significantly between male and female patients (p<!--> <!-->=<!--> <!-->0.114) or between patients aged<!--> <!-->&lt;<!--> <!-->65 and ≥<!--> <!-->65 years (p<!--> <!-->=<!--> <!-->0.573). Overall, median pain scores decreased from 6 (5-7) before the procedure to 2 (2-4) after the procedure. Procedure duration was 1.54<!--> <!-->±<!--> <!-->0.3<!--> <!-->min and did not differ by sex or age. The majority of patients (81.2%) would undergo repeat cystoscopy if required, with no significant difference between male and female patients.</div></div><div><h3>Conclusions</h3><div>Patients undergoing office-based cystoscopy report significantly lower pain than anticipated, and these findings may inform clinical counseling by facilitating reassurance and contributing to reduced anxiety through effective pre-procedural education.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 502032"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Futuro de Actas Urológicas Españolas: una revista científica, una identidad y una proyección internacional","authors":"Ó. Rodríguez Faba","doi":"10.1016/j.acuro.2026.502073","DOIUrl":"10.1016/j.acuro.2026.502073","url":null,"abstract":"","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 502073"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asociación entre la transfusión sanguínea perioperatoria y los resultados de supervivencia en pacientes intervenidos de cistectomía radical por tumor vesical","authors":"R. Monsonís Usó,&nbsp;P. Ponce Blasco,&nbsp;Á. Canos Nebot,&nbsp;L. Barrios Arnau,&nbsp;A. Sánchez Llopis,&nbsp;C. Garau Perelló,&nbsp;M. Bosquet Sanz,&nbsp;P. Juan Verdoy,&nbsp;M. Rodrigo Aliaga","doi":"10.1016/j.acuro.2026.502001","DOIUrl":"10.1016/j.acuro.2026.502001","url":null,"abstract":"<div><h3>Introduction</h3><div>Perioperative blood transfusion (BT) has been suggested as a potential prognostic factor in patients undergoing radical cystectomy (RC) for bladder cancer, although its impact remains controversial. We aimed to evaluate the association between perioperative BT and short- and long-term outcomes in a contemporary single-center RC series.</div></div><div><h3>Materials and methods</h3><div>We retrospectively analyzed consecutive patients who underwent RC for bladder cancer at our institution between 2017 and 2024. Demographic, perioperative, and pathological variables were collected. Outcomes included 30-day mortality, overall survival (OS), and cancer-specific survival (CSS). Survival analyses were performed using Kaplan–Meier estimates and compared with the <em>log-rank</em> test. Multivariable Cox and logistic regression models were constructed to adjust for potential confounders.</div></div><div><h3>Results</h3><div>A total of 200 patients were included (median age 69 years [31–88]), of whom 105 (52.5%) received perioperative blood transfusion (BT). Median estimated blood loss was 700<!--> <!-->mL (100–3500). Thirty-day mortality was 6% (12 patients). Overall survival (OS) was 63.5% (127 patients), and cancer-specific survival (CSS) was 72.5% (145 patients) at the end of follow-up. Perioperative BT was significantly associated with worse overall survival (HR 3.28, 95% CI 1.88–5.72, p &lt;<!--> <!-->0.001), cancer-specific survival (HR 5.33, 95% CI 2.55–11.13, p &lt;<!--> <!-->0.001), and increased 30-day postoperative mortality (OR 10.88, 95% CI 1.38–85.6, p<!--> <!-->=<!--> <!-->0.024). In multivariable analyses, perioperative BT remained independently associated with worse OS and CSS, together with advanced pathological T stage, positive nodal status, and higher ASA score, but was not independently associated with 30-day mortality.</div></div><div><h3>Conclusions</h3><div>Perioperative blood transfusion was associated with worse overall and cancer-specific survival after radical cystectomy, but not with early postoperative mortality after adjustment. These findings should be interpreted as an association rather than a causal relationship, as residual confounding cannot be excluded. Strategies aimed at optimizing preoperative anaemia and reducing transfusion requirements may contribute to improving perioperative management in patients undergoing radical cystectomy.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 502001"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recomendaciones para la prevención y el tratamiento de los efectos adversos del BCG intravesical","authors":"J.L. Alvarez-Ossorio,&nbsp;M. Alvarez-Maestro,&nbsp;J.M. Cozar-Olmo,&nbsp;M. Espinosa-Bosch,&nbsp;I. Florido-Pérez,&nbsp;F. Guerrero-Ramos,&nbsp;L. Martinez-Piñeiro,&nbsp;J. Olivares-Corral,&nbsp;M. Rodriguez-Quecedo,&nbsp;O. Rodriguez-Faba","doi":"10.1016/j.acuro.2026.502005","DOIUrl":"10.1016/j.acuro.2026.502005","url":null,"abstract":"<div><div>Intravesical Calmette-Guérin bacillus (BCG) instillation is the treatment of choice after transurethral resection of intermediate- and high-risk non-muscle-invasive bladder tumors (NMIBT). However, adverse effects (AEs) of BCG are common and can compromise adherence to treatment.</div><div>Therefore, a group of experts in urology, hospital pharmacy and nursing reviewed the most recent literature and developed a series of practical recommendations for the prevention, early detection, and treatment of adverse events (AEs) associated with BCG vaccination. These include a questionnaire for AE detection, the treatment of the most common local and systemic AEs, and precautionary recommendations, ranging from BCG preparation to excreta management. Special attention has been given to a multidisciplinary and coordinated approach between urologists, hospital pharmacists and nurses to optimize treatment adherence.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 502005"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconstruyendo lo reconstruido: resultados de la uretroplastia de repetición en estenosis uretrales recurrentes","authors":"R. Uğur,&nbsp;E.T. Keskin,&nbsp;M. Savun,&nbsp;E. Aktaş,&nbsp;A. Şimşek","doi":"10.1016/j.acuro.2026.501996","DOIUrl":"10.1016/j.acuro.2026.501996","url":null,"abstract":"<div><h3>Introduction</h3><div>In this study, we aimed to evaluate the results of redo-urethroplasty and to determine the risk factors contributing to the recurrence of stricture.</div></div><div><h3>Methods</h3><div>Male patients with a history of urethroplasty who underwent redo-urethroplasty were retrospectively evaluated and included in the study. Classifications were made according to patient characteristics, features of the stricture, and the surgical procedure performed. Success criteria was defined as anatomical success, which was determined by the resistance-free passage of a 16-Fr flexible cystoscope through the reconstructed urethral lumen. After identifying the influencing factors, univariate and multivariable logistic regression analyses were conducted to determine the predictors for recurrence.</div></div><div><h3>Results</h3><div>A total of 396 male patients who underwent urethroplasty were evaluated, with 76 patients meeting the established criteria for inclusion. The mean age was 42.3 (10-81) years, and the average follow-up period was 44 (13-78) months. The majority of patients (54%) had bulbar strictures, and the average stricture length was 4.8<!--> <!-->±<!--> <!-->2.4 (1.3-12) cm. Treatment success was achieved in 72.4% of patients. In univariate analyses, factors statistically significantly (<em>P</em> <!-->&lt;<!--> <!-->.05) associated with recurrence included smoking, diabetes mellitus, stricture length, etiology, and the presence of complications. In the multivariable logistic regression analysis, presence of complications remained statistically significant (<em>P</em> <!-->&lt;<!--> <!-->.05) as an independent predictor of recurrence.</div></div><div><h3>Conclusions</h3><div>Smoking, diabetes mellitus, stricture length, etiology, and postoperative complications were significantly associated with stricture recurrence. These results suggest that patient-related, stricture-related, and perioperative factors influence recurrence risk after redo-urethroplasty.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 501996"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resultados comparativos de la mini-PCNL y la ureteroscopia flexible asistida por aspiración en pacientes con litiasis renales ≥ 2 cm","authors":"H. Mert Durak,&nbsp;A. Sancı,&nbsp;E. Hepşen,&nbsp;O. Burak Karadağ,&nbsp;M. Yığman,&nbsp;K. Sarıkaya,&nbsp;A. Levent Sağnak","doi":"10.1016/j.acuro.2026.501997","DOIUrl":"10.1016/j.acuro.2026.501997","url":null,"abstract":"<div><h3>Introduction</h3><div>To compare the efficacy and perioperative outcomes of miniaturized percutaneous nephrolithotomy (mini-PCNL) and flexible ureteroscopy with flexible and navigable suction ureteral access sheath (FANS-UAS) in the management of renal stones larger than 2<!--> <!-->cm.</div></div><div><h3>Material and method</h3><div>This retrospective comparative study evaluated 252 adults with renal stones ≥2<!--> <!-->cm treated between May 2024 and December 2025. Mini-PCNL was performed in 142 patients and FANS-UAS–assisted flexible ureteroscopy in 110. Preoperative non-contrast CT was used to characterize stones, and postoperative CT determined stone-free status as the primary endpoint. Operative time, hemoglobin drop, length of stay, Clavien–Dindo complications, and auxiliary intervention rates were analyzed as secondary outcomes.</div></div><div><h3>Results</h3><div>Stone-free rates did not differ significantly between mini-PCNL and FANS-UAS–assisted flexible ureteroscopy (83.1% vs. 76.4%, p<!--> <!-->=<!--> <!-->0.242). Mini-PCNL provided shorter operative times but resulted in greater hemoglobin decline, longer hospitalization, and more minor complications, while major complications were similar. Although mini-PCNL yielded higher stone-free rates in lower pole stones, this was not statistically significant. FANS-UAS was more frequently applied in older, comorbid patients and maintained satisfactory efficacy with a favorable perioperative profile.</div></div><div><h3>Conclusions</h3><div>Both mini-PCNL and FANS-UAS–assisted flexible ureteroscopy achieved effective stone clearance for renal stones<!--> <!-->&gt;2<!--> <!-->cm. Mini-PCNL was faster, whereas FANS-UAS was associated with lower perioperative morbidity, despite lower adjusted odds of stone-free status compared with mini-PCNL. These results support an individualized approach to procedure selection in large renal stones, with stone burden, lower pole involvement, and patient comorbidity considered together in treatment planning.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 501997"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resultados funcionales de un programa de entrenamiento del suelo pélvico con biofeedback tras prostatectomía radical asistida por robot","authors":"I. Millán-Ramos,&nbsp;A. Zambudio-Munuera,&nbsp;A. Donaire-Barrera,&nbsp;P. Rodríguez-Parras,&nbsp;M.I. Martinez-Sanchez,&nbsp;M. Arrabal-Martín,&nbsp;M.A. Arrabal-Polo","doi":"10.1016/j.acuro.2026.501999","DOIUrl":"10.1016/j.acuro.2026.501999","url":null,"abstract":"<div><h3>Objective</h3><div>Urinary incontinence remains one of the main functional sequelae after robot-assisted radical prostatectomy (RARP). This study aimed to evaluate urinary continence and functional outcomes in patients enrolled in a structured postoperative pelvic floor muscle training programme with biofeedback.</div></div><div><h3>Methods</h3><div>We conducted a single-centre retrospective observational study including consecutive patients who underwent RARP between November 2024 and October 2025 and entered a postoperative biofeedback-guided pelvic floor rehabilitation programme, with a minimum follow-up of 3 months. Patients with previous pelvic radiotherapy, preoperative urinary incontinence or incomplete key data were excluded. Biofeedback was started 12–14 days after hospital discharge, coinciding with catheter removal, and included 3–4 supervised sessions according to clinical progress, together with a home exercise programme. The primary outcome was urinary continence, defined as the use of 0–1 pad/day, at 3 and 6 months after surgery.</div></div><div><h3>Results</h3><div>Ninety patients were included. Mean age was 64.4<!--> <!-->±<!--> <!-->6.3 years and mean body mass index was 29.1<!--> <!-->±<!--> <!-->4.3<!--> <!-->kg/m². Continence rates were 88.9% at 3 months and 94.4% at 6 months. Lower 24-hour pad test values were significantly associated with continence at the first and second follow-up visits (both p&lt;<!--> <!-->0.001). No significant associations were found between 3-month continence and age, body mass index, preoperative PSA, prostate volume or catheterisation time. Nevertheless, the number of biofeedback sessions was significantly associated with continence recovery, suggesting a possible dose-response effect.</div></div><div><h3>Conclusions</h3><div>A structured postoperative pelvic floor rehabilitation programme with biofeedback was associated with high rates of early continence recovery after RARP. The intensity of supervised rehabilitation may influence functional recovery. Prospective controlled studies are warranted to confirm these findings.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 501999"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eficacia y seguridad de mirabegrón en población pediátrica: un estudio observacional prospectivo","authors":"L.E. Zelaya-Contreras,&nbsp;M. Ruiz-Medina,&nbsp;V. Vargas Cruz,&nbsp;R.M. Paredes Estebán,&nbsp;A. Parente Hernández","doi":"10.1016/j.acuro.2026.502000","DOIUrl":"10.1016/j.acuro.2026.502000","url":null,"abstract":"<div><h3>Introduction</h3><div>Standard treatments for paediatric lower urinary tract dysfunction, including anticholinergics and intravesical botulinum toxin, may be limited by adverse effects and suboptimal response. Mirabegron, a β3-adrenergic receptor agonist, offers an alternative mechanism of action; however, paediatric evidence remains limited. This study aimed to evaluate its safety and clinical efficacy.</div></div><div><h3>Materials and Methods</h3><div>A prospective observational study included patients treated with mirabegron between November 2023 and November 2024, with follow-up until November 2025. Mirabegron was used as second- or third-line therapy. Clinical response was assessed based on changes in urinary symptoms (frequency, urgency, nocturnal enuresis, and daytime urinary incontinence) and categorised as complete improvement (resolution), partial improvement (reduction), or no change. Adverse events were recorded. In a subgroup, urodynamic para</div><div>meters were assessed before and after treatment.</div></div><div><h3>Results</h3><div>Fifteen patients were included (mean age 12 years), with a mean treatment duration of 12 months. Clinical improvement was observed in 78% of patients. Paired urodynamic studies were available in seven patients, showing significant improvements in maximum cystometric capacity, bladder compliance, and detrusor pressure during filling. Two patients experienced mild adverse events. One patient discontinued treatment due to difficulty swallowing the tablet. No clinically relevant cardiovascular changes were obs</div><div>erved.</div></div><div><h3>Conclusions</h3><div>Mirabegron demonstrated a favourable safety profile and was associated with clinically meaningful improvement in symptoms and urodynamic parameters, supporting its use in selected paediatric patients with lower urinary tract dysfunction.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"50 8","pages":"Article 502000"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}