Actas urologicas espanolas最新文献_第7页

Elaboración de un modelo experimental en conejos con diferentes grados de torsión testicular 在兔子身上建立不同程度睾丸扭转的实验模型。

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-10-01 DOI: 10.1016/j.acuro.2024.04.007

X. Zhu , C. Peng , Z. Wu , X. Zhang , S. Liu , Y. Luo , L. Yang

{"title":"Elaboración de un modelo experimental en conejos con diferentes grados de torsión testicular","authors":"X. Zhu , C. Peng , Z. Wu , X. Zhang , S. Liu , Y. Luo , L. Yang","doi":"10.1016/j.acuro.2024.04.007","DOIUrl":"10.1016/j.acuro.2024.04.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Different degrees of testicular torsion result in varying degrees of testicular damage, which influences treatment options and outcomes. Therefore, establishing a testicular torsion model with different degrees is necessary for clinical diagnosis.</div></div><div><h3>Materials and methods</h3><div>Rabbits were randomly divided into 4groups and their spermatic cords were twisted at 0°, 180°, 360°, and 720°, respectively. Color Doppler flow imaging (CDFI) were performed to evaluate the blood supply in testicles. The twisted testicles were surgically removed at 6hours post-operation and were evaluated by morphological observation and Hematoxylin and Eosin staining.</div></div><div><h3>Results</h3><div>CDFI signals were gradually decreased as the degree of testicular torsion increased, and scores of CDFI in the 360° and 720° groups were significantly decreased at postoperative 6hours compared to pre-surgery. Compared to the sham, the testicle in the 180° group exhibited slight congestion, whereas the testicles in the 360° and 720° groups were dark red in color and had severe congestion and unrecognizable vessels. Hematoxylin and Eosin staining showed mild spermatogenic cell reduction and testicular interstitial hemorrhage in the 180° group. In the 360° and 720° groups, disordered seminiferous tubules, shed spermatogenic cells in tubules, inflammatory cell infiltration, and severe hemorrhage were found. In comparison with the sham, interstitial hemorrhage scores in the 360° and 720° groups were significantly higher, and scores of germinal epithelial cell thickness in the 3testicular torsion groups were significantly decreased.</div></div><div><h3>Conclusion</h3><div>Collectively, we successfully constructed a testicular torsion model with different degrees in rabbits.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 8","pages":"Pages 565-573"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142419845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colposacropexia robótica para el tratamiento del prolapso de órganos pélvicos en mujeres de edad avanzada: análisis comparativo de la seguridad y eficacia frente a mujeres jóvenes 机器人阴道环切术治疗老年妇女盆腔器官脱垂：安全性和有效性与年轻妇女的比较分析

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-10-01 DOI: 10.1016/j.acuro.2024.04.005

{"title":"Colposacropexia robótica para el tratamiento del prolapso de órganos pélvicos en mujeres de edad avanzada: análisis comparativo de la seguridad y eficacia frente a mujeres jóvenes","authors":"","doi":"10.1016/j.acuro.2024.04.005","DOIUrl":"10.1016/j.acuro.2024.04.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Pelvic organ prolapse is a condition with high prevalence in elderly women. With increasing life expectancy and a desire for improved quality of life, a rise in the frequency of surgical treatments for these women is anticipated. The aim is to compare complication, success, and satisfaction rates among elderly patients (aged>70 years) in comparison to younger women undergoing robotic sacrocolpopexy, thereby assessing the safety and efficacy of this surgery in this group of patients.</div></div><div><h3>Method</h3><div>A prospective observational comparative study of 123 robotic sacrocolpopexies conducted between December 2016 and June 2022. Patients were stratified by age (cutoff point: 70 years). Baseline characteristics, type, and grade of prolapse, intra and postoperative data, complications, functional and anatomical outcomes, and satisfaction levels were collected.</div></div><div><h3>Results</h3><div>Among the 123 patients, 62.6% were under 70 years old, while 37.4% were 70 years or older, exhibiting similar baseline characteristics, prolapse grade, and type. The percentages of intraoperative (6.5%) and postoperative complications (4.4-9%) were comparable in both age groups. Furthermore, success and satisfaction rates exceeded 90%, with no significant differences between women under and over 70 years during a two-year follow-up.</div></div><div><h3>Conclusion</h3><div>Robotic sacrocolpopexy is at least as effective and safe in women aged 70 years or older as in younger individuals, with no higher rates of intra and postoperative complications and similar rates of anatomical and subjective success.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 8","pages":"Pages 611-617"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141041665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

El periplo de la determinación de la expresión de PD-L1 en el carcinoma urotelial infiltrante 确定浸润性尿路上皮癌中 PD-L1 的表达：西班牙病理解剖学会的建议。

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-10-01 DOI: 10.1016/j.acuro.2024.04.006

引用次数: 0

Utilidad de Bladder Epicheck® en el seguimiento del tumor de vejiga no músculo infiltrante: revisión sistemática de la literatura 膀胱Epicheck®在非肌浸润性膀胱肿瘤随访中的作用：文献系统回顾

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-10-01 DOI: 10.1016/j.acuro.2024.02.004

{"title":"Utilidad de Bladder Epicheck® en el seguimiento del tumor de vejiga no músculo infiltrante: revisión sistemática de la literatura","authors":"","doi":"10.1016/j.acuro.2024.02.004","DOIUrl":"10.1016/j.acuro.2024.02.004","url":null,"abstract":"<div><h3>Introduction</h3><div>In recent years, different urinary markers such as the Bladder Epicheck® have been developed in an attempt to reduce the number of cystoscopies in the follow-up of non-muscle invasive bladder cancer (NMIBC).</div></div><div><h3>Aim</h3><div>To provide a systematic review of Bladder Epicheck® and its current clinical utility in the follow-up and detection of recurrence of NMIBC.</div></div><div><h3>Material and methods</h3><div>Systematic review based on a literature search of PubMed, Web of Science and Scopus databases until October 2023, according to PRISMA and Quadas-2 criteria. Sensitivity (Se), specificity (Sp), positive predictive value (PPV) and negative predictive value (NPV) of the marker were calculated. Diagnostic performance was evaluated by the area under the curve (AUC).</div></div><div><h3>Results</h3><div>Fifteen studies were analyzed (n=3761) including 86.7% prospective studies. Of the patient series, 53.2% had received previous intravesical instillations. The mean Se of the biomarker in the detection of recurrence varied according to tumor grade (87.9%-high grade/HG vs. 44.9%-low grade/LG, respectively). Their weighted mean Se and Sp were 71.6% and 84.5%, respectively. The mean recurrence rate was 29.1%. The weighted mean PPV and NPV were 56.4% and 92.8% (97.7% non-LG), respectively. The mean AUC was 85.63%.</div></div><div><h3>Conclusion</h3><div>Bladder Epicheck® is a useful urinary marker in the follow-up of NMIBC, with significantly high Se and NPV in the detection of recurrences, especially in cases of HG disease. Its use can reduce the number of cystoscopies required in the follow-up of NMIBC, improving the quality of life of patients and potentially increasing health economic savings.</div></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 8","pages":"Pages 555-564"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140406235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impacto del tamaño de la lesión en las tasas de detección del cáncer de próstata clínicamente significativo en lesiones PI-RADS 3-5 病变大小对 PI-RADS 病变中具有临床意义的前列腺癌检出率的影响 3-5

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.01.003

A. Ayranci, U. Caglar, A. Meric, M. Gelmis, O. Sarilar, F. Ozgor

{"title":"Impacto del tamaño de la lesión en las tasas de detección del cáncer de próstata clínicamente significativo en lesiones PI-RADS 3-5","authors":"A. Ayranci, U. Caglar, A. Meric, M. Gelmis, O. Sarilar, F. Ozgor","doi":"10.1016/j.acuro.2024.01.003","DOIUrl":"10.1016/j.acuro.2024.01.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Prostate cancer (PCa) ranks second among prevalent cancers in men, necessitating effective screening tools such as multiparametric magnetic resonance imaging (mpMRI) with the prostate imaging reporting and data system (PI-RADS) classification. This study explores the impact of lesion volume on clinically significant prostate cancer (csPCa) detection rates in PI-RADS 3–5 lesions, aiming to contribute insights into the underexplored relationship between lesion size and csPCa detection.</p></div><div><h3>Materials and methods</h3><p>A retrospective analysis was conducted on data from 754 patients undergoing mpMRI-guided transrectal ultrasound (TRUS) prostate biopsy between January 2016 and 2023. Patients with PI-RADS 3, 4, and 5 lesions were included. Lesion size and PI-RADS categories were assessed through mpMRI, followed by MR fusion biopsy.</p></div><div><h3>Results</h3><p>Of the patients, 33.7%, 52.3%, and 14.1% had PI-RADS 3, 4, and 5 lesions, respectively. Lesion sizes correlated significantly with csPCa detection in PI-RADS 4 and 5 categories. For PI-RADS 3 lesions, no significant differences in csPCa rates were observed based on lesion size. However, in PI-RADS 4 and 5 groups, larger lesions showed higher csPCa rates.</p></div><div><h3>Conclusions</h3><p>This study suggests that subgroup categorizations based on lesion volume could predict clinically significant PCa with high accuracy, potentially reducing unnecessary biopsies and associated overtreatment. Future research should further explore the relationship between lesion size and csPCa, clarifying discussions regarding the inclusion of systematic biopsies in diagnostic protocols.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 526-531"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efecto de la edad, el periodo y la cohorte en la incidencia del cáncer renal en España entre 1990 y 2019: datos del estudio Global Burden of Disease 1990 年至 2019 年间年龄、时期和队列对西班牙肾癌发病率的影响：来自全球疾病负担研究的数据。

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.02.003

{"title":"Efecto de la edad, el periodo y la cohorte en la incidencia del cáncer renal en España entre 1990 y 2019: datos del estudio Global Burden of Disease","authors":"","doi":"10.1016/j.acuro.2024.02.003","DOIUrl":"10.1016/j.acuro.2024.02.003","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to assess the influence of age, period, and cohort (A-P-C) factors on kidney cancer (KC) incidence trends in Spain from 1990 to 2019.</p></div><div><h3>Methods</h3><p>Employing data from the Global Burden of Disease Study 2019, we employed joinpoint analysis to determine long-term patterns and A-P-C modelling to quantify net drift, local drift, longitudinal age curves, and rate ratios (RRs) of period and cohort effects.</p></div><div><h3>Results</h3><p>Over the period 1990-2019, an estimated 142,811 cases of KC were diagnosed in Spain. A consistent upward trend in KC incidence was observed for both men and women, with the male-to-female ratio remaining stable at 2.6. Joinpoint analysis identified three distinct periods for men: An initial period (1990-1995) characterised by a significant increase in rates, a subsequent period (1995-2016) characterised by a slowdown in the rate of increase, and a final period (2016-2019) in which rates have plateaued. In women, 2 time periods were observed: an initial period (1990-2007) in which rates increased significantly, followed by a period of stabilization (2007-2019).</p><p>Men born in the early-mid 20th century had a rising KC risk, peaking in the 1960s. Women's risk rose steadily, peaking in the late 1990s.</p></div><div><h3>Conclusion</h3><p>A-P-C analysis reveals steady KC incidence increase in both genders over three decades. This highlights the need for targeted public health policies and effective prevention strategies.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 538-544"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ensayo clínico aleatorizado: utilización de la luz IMAGE1S (SPIES) vs. luz blanca durante la resección transuretral de tumores vesicales para la prevención de recurrencias, análisis a los 12 meses de seguimiento 随机临床试验：在经尿道膀胱肿瘤切除术中使用 IMAGE1S (SPIES) 光与白光以预防复发，12 个月随访分析。

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2023.10.004

{"title":"Ensayo clínico aleatorizado: utilización de la luz IMAGE1S (SPIES) vs. luz blanca durante la resección transuretral de tumores vesicales para la prevención de recurrencias, análisis a los 12 meses de seguimiento","authors":"","doi":"10.1016/j.acuro.2023.10.004","DOIUrl":"10.1016/j.acuro.2023.10.004","url":null,"abstract":"<div><h3>Introduction</h3><p>The improved image resolution of IMAGE1 S technology will increase tumor detection, achieve a greater number of complete resections, and would probably have an impact on the reduction of recurrences.</p></div><div><h3>Aim</h3><p>The primary objective was to compare the recurrence rates of IMAGE1 S vs. white light during transurethral resection of the bladder; the secondary objective was to compare the complication rates according to Clavien-Dindo at 12 months of follow-up.</p></div><div><h3>Methodolgy</h3><p>Prospective, randomized 1:1, blinded clinical trial. Recurrence and complication rates according to Clavien-Dindo were analyzed using chi-square/U Mann-Whitney tests, and recurrence-free survival using Kaplan-Meier curves. The European Association of Urology 2021 scoring model was used.</p></div><div><h3>Results</h3><p>The analysis included 103 participants; 49 were assigned to the IMAGE1 S group and 54 to the white light group. Recurrence rates were 12.2% and 25.9%, respectively (<em>P</em>  =.003) and a higher recurrence-free survival with IMAGE1 S (85.2% vs. 62.8% Log Rank: 0.021), with a Hazard Ratio of 0.215 (95% CI: 0.046-0.925). No differences were observed in the high and very high-risk groups. Complications were mostly grade I and rates were similar between both groups (IMAGE1 S 20.4% vs. white light 7.4% <em>P</em>  <!-->.083).</p></div><div><h3>Conclusions</h3><p>There were no differences in the recurrence rates between groups. However, the low and intermediate risk group had a lower recurrence rate with IMAGE1 S. In addition, perioperative complication rates were not higher.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 512-520"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estado de la formación robótica en la residencia de urología: resultados de una encuesta nacional en España 泌尿外科住院医师机器人培训现状：西班牙全国调查结果

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.01.015

N. García-Formoso , R. Ballestero Diego , E. Seguí-Moya , E. Herrero Blanco , C. Mercader Barrull , D.A. González-Padilla , J.M. Benejam Gual

{"title":"Estado de la formación robótica en la residencia de urología: resultados de una encuesta nacional en España","authors":"N. García-Formoso , R. Ballestero Diego , E. Seguí-Moya , E. Herrero Blanco , C. Mercader Barrull , D.A. González-Padilla , J.M. Benejam Gual","doi":"10.1016/j.acuro.2024.01.015","DOIUrl":"10.1016/j.acuro.2024.01.015","url":null,"abstract":"<div><h3>Introduction and objective</h3><p>The increasing number of robotic urological procedures observed in recent years highlights the need to expand training opportunities in robotic surgery. Our objective is to investigate the state of robotic training during urology residency in Spain in order to identify significant deficiencies.</p></div><div><h3>Materials and methods</h3><p>A 20-item online survey was conducted among urology residents in Spain who were registered in the database of the Residents and Young Urologists Group of the Spanish Association of Urology. The survey assessed subjective opinions, institutional aspects, training resources, and experience regarding robotic surgery. A total of 455 email invitations were sent throughout the year 2021. Descriptive analysis of the responses was performed.</p></div><div><h3>Results</h3><p>The participation rate reached 30%, with a total of 135 residents. The 52% of respondents lacked access to a robotic system in their institution, of which only 48% could compensate for this deficiency through external rotations. Among those with access to a robotic system, 25% and 23% reported having access to theoretical and practical training, respectively. The existence of a formal training program was low (13%) and 85% of the respondents considered robotic surgery training in Spain to be deficient.</p></div><div><h3>Conclusions</h3><p>Training for Spanish residents in robotic urological surgery is perceived as inadequate, emphasizing the crucial need for improvement in training programs in this field.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 545-551"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

¿Por qué es necesario tener una cepa de BCG fabricada en España? 为什么必须在西班牙生产 bcg 菌株？

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.01.006

引用次数: 0

Prevalencia y manejo de la incontinencia urinaria asociada a cirugía de prolapso órgano pélvico (colposacropexia). Revisión de la literatura 与盆腔器官脱垂手术（COLPOSACROPEXY）相关的尿失禁的发生率和处理。文献综述

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2023.11.005

{"title":"Prevalencia y manejo de la incontinencia urinaria asociada a cirugía de prolapso órgano pélvico (colposacropexia). Revisión de la literatura","authors":"","doi":"10.1016/j.acuro.2023.11.005","DOIUrl":"10.1016/j.acuro.2023.11.005","url":null,"abstract":"<div><h3>Introduction</h3><p>Stress urinary incontinence (SUI) is frequently associated with pelvic organ prolapse (POP) and may occur after its surgical treatment.</p></div><div><h3>Aim</h3><p>To determine the incidence, risk factors and management of SUI during and after POP surgery through a review of the available literature.</p></div><div><h3>Materials and method</h3><p>Narrative literature review on the incidence and management of SUI after POP surgery after search of relevant manuscripts indexed in PubMed, EMBASE and Scielo published in Spanish or English between 2013-2023.</p></div><div><h3>Results</h3><p>Occult SUI is defined as visible urine leakage when prolapse is reduced in patients without SUI symptoms. De novo SUI develops after prolapse surgery without having previously existed. In continent patients, the number needed to treat (NNT) to prevent one case of de novo SUI is estimated to be 9 patients and about 17 to avoid repeat incontinence surgery. In patients with occult UI, the NNT to avoid repeat incontinence surgery is around 7. Patients with POP and concomitant SUI are the group most likely to benefit from combined surgery with a more favorable NNT (NNT2).</p></div><div><h3>Conclusion</h3><p>Quality studies on combined surgery for treatment SUI and POP repair are lacking. Continent patients with prolapse should be warned of the risk of de novo SUI, although concomitant incontinence treatment is not currently recommended. Incontinence surgery should be considered on an individual basis in patients with prolapse and SUI.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 490-496"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139193931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0