Actas urologicas espanolas最新文献_第5页

Impacto del tamaño de la lesión en las tasas de detección del cáncer de próstata clínicamente significativo en lesiones PI-RADS 3-5 病变大小对 PI-RADS 病变中具有临床意义的前列腺癌检出率的影响 3-5

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.01.003

A. Ayranci, U. Caglar, A. Meric, M. Gelmis, O. Sarilar, F. Ozgor

{"title":"Impacto del tamaño de la lesión en las tasas de detección del cáncer de próstata clínicamente significativo en lesiones PI-RADS 3-5","authors":"A. Ayranci, U. Caglar, A. Meric, M. Gelmis, O. Sarilar, F. Ozgor","doi":"10.1016/j.acuro.2024.01.003","DOIUrl":"10.1016/j.acuro.2024.01.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Prostate cancer (PCa) ranks second among prevalent cancers in men, necessitating effective screening tools such as multiparametric magnetic resonance imaging (mpMRI) with the prostate imaging reporting and data system (PI-RADS) classification. This study explores the impact of lesion volume on clinically significant prostate cancer (csPCa) detection rates in PI-RADS 3–5 lesions, aiming to contribute insights into the underexplored relationship between lesion size and csPCa detection.</p></div><div><h3>Materials and methods</h3><p>A retrospective analysis was conducted on data from 754 patients undergoing mpMRI-guided transrectal ultrasound (TRUS) prostate biopsy between January 2016 and 2023. Patients with PI-RADS 3, 4, and 5 lesions were included. Lesion size and PI-RADS categories were assessed through mpMRI, followed by MR fusion biopsy.</p></div><div><h3>Results</h3><p>Of the patients, 33.7%, 52.3%, and 14.1% had PI-RADS 3, 4, and 5 lesions, respectively. Lesion sizes correlated significantly with csPCa detection in PI-RADS 4 and 5 categories. For PI-RADS 3 lesions, no significant differences in csPCa rates were observed based on lesion size. However, in PI-RADS 4 and 5 groups, larger lesions showed higher csPCa rates.</p></div><div><h3>Conclusions</h3><p>This study suggests that subgroup categorizations based on lesion volume could predict clinically significant PCa with high accuracy, potentially reducing unnecessary biopsies and associated overtreatment. Future research should further explore the relationship between lesion size and csPCa, clarifying discussions regarding the inclusion of systematic biopsies in diagnostic protocols.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 526-531"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efecto de la edad, el periodo y la cohorte en la incidencia del cáncer renal en España entre 1990 y 2019: datos del estudio Global Burden of Disease 1990 年至 2019 年间年龄、时期和队列对西班牙肾癌发病率的影响：来自全球疾病负担研究的数据。

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.02.003

{"title":"Efecto de la edad, el periodo y la cohorte en la incidencia del cáncer renal en España entre 1990 y 2019: datos del estudio Global Burden of Disease","authors":"","doi":"10.1016/j.acuro.2024.02.003","DOIUrl":"10.1016/j.acuro.2024.02.003","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to assess the influence of age, period, and cohort (A-P-C) factors on kidney cancer (KC) incidence trends in Spain from 1990 to 2019.</p></div><div><h3>Methods</h3><p>Employing data from the Global Burden of Disease Study 2019, we employed joinpoint analysis to determine long-term patterns and A-P-C modelling to quantify net drift, local drift, longitudinal age curves, and rate ratios (RRs) of period and cohort effects.</p></div><div><h3>Results</h3><p>Over the period 1990-2019, an estimated 142,811 cases of KC were diagnosed in Spain. A consistent upward trend in KC incidence was observed for both men and women, with the male-to-female ratio remaining stable at 2.6. Joinpoint analysis identified three distinct periods for men: An initial period (1990-1995) characterised by a significant increase in rates, a subsequent period (1995-2016) characterised by a slowdown in the rate of increase, and a final period (2016-2019) in which rates have plateaued. In women, 2 time periods were observed: an initial period (1990-2007) in which rates increased significantly, followed by a period of stabilization (2007-2019).</p><p>Men born in the early-mid 20th century had a rising KC risk, peaking in the 1960s. Women's risk rose steadily, peaking in the late 1990s.</p></div><div><h3>Conclusion</h3><p>A-P-C analysis reveals steady KC incidence increase in both genders over three decades. This highlights the need for targeted public health policies and effective prevention strategies.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 538-544"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ensayo clínico aleatorizado: utilización de la luz IMAGE1S (SPIES) vs. luz blanca durante la resección transuretral de tumores vesicales para la prevención de recurrencias, análisis a los 12 meses de seguimiento 随机临床试验：在经尿道膀胱肿瘤切除术中使用 IMAGE1S (SPIES) 光与白光以预防复发，12 个月随访分析。

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2023.10.004

{"title":"Ensayo clínico aleatorizado: utilización de la luz IMAGE1S (SPIES) vs. luz blanca durante la resección transuretral de tumores vesicales para la prevención de recurrencias, análisis a los 12 meses de seguimiento","authors":"","doi":"10.1016/j.acuro.2023.10.004","DOIUrl":"10.1016/j.acuro.2023.10.004","url":null,"abstract":"<div><h3>Introduction</h3><p>The improved image resolution of IMAGE1 S technology will increase tumor detection, achieve a greater number of complete resections, and would probably have an impact on the reduction of recurrences.</p></div><div><h3>Aim</h3><p>The primary objective was to compare the recurrence rates of IMAGE1 S vs. white light during transurethral resection of the bladder; the secondary objective was to compare the complication rates according to Clavien-Dindo at 12 months of follow-up.</p></div><div><h3>Methodolgy</h3><p>Prospective, randomized 1:1, blinded clinical trial. Recurrence and complication rates according to Clavien-Dindo were analyzed using chi-square/U Mann-Whitney tests, and recurrence-free survival using Kaplan-Meier curves. The European Association of Urology 2021 scoring model was used.</p></div><div><h3>Results</h3><p>The analysis included 103 participants; 49 were assigned to the IMAGE1 S group and 54 to the white light group. Recurrence rates were 12.2% and 25.9%, respectively (<em>P</em>  =.003) and a higher recurrence-free survival with IMAGE1 S (85.2% vs. 62.8% Log Rank: 0.021), with a Hazard Ratio of 0.215 (95% CI: 0.046-0.925). No differences were observed in the high and very high-risk groups. Complications were mostly grade I and rates were similar between both groups (IMAGE1 S 20.4% vs. white light 7.4% <em>P</em>  <!-->.083).</p></div><div><h3>Conclusions</h3><p>There were no differences in the recurrence rates between groups. However, the low and intermediate risk group had a lower recurrence rate with IMAGE1 S. In addition, perioperative complication rates were not higher.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 512-520"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estado de la formación robótica en la residencia de urología: resultados de una encuesta nacional en España 泌尿外科住院医师机器人培训现状：西班牙全国调查结果

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.01.015

N. García-Formoso , R. Ballestero Diego , E. Seguí-Moya , E. Herrero Blanco , C. Mercader Barrull , D.A. González-Padilla , J.M. Benejam Gual

{"title":"Estado de la formación robótica en la residencia de urología: resultados de una encuesta nacional en España","authors":"N. García-Formoso , R. Ballestero Diego , E. Seguí-Moya , E. Herrero Blanco , C. Mercader Barrull , D.A. González-Padilla , J.M. Benejam Gual","doi":"10.1016/j.acuro.2024.01.015","DOIUrl":"10.1016/j.acuro.2024.01.015","url":null,"abstract":"<div><h3>Introduction and objective</h3><p>The increasing number of robotic urological procedures observed in recent years highlights the need to expand training opportunities in robotic surgery. Our objective is to investigate the state of robotic training during urology residency in Spain in order to identify significant deficiencies.</p></div><div><h3>Materials and methods</h3><p>A 20-item online survey was conducted among urology residents in Spain who were registered in the database of the Residents and Young Urologists Group of the Spanish Association of Urology. The survey assessed subjective opinions, institutional aspects, training resources, and experience regarding robotic surgery. A total of 455 email invitations were sent throughout the year 2021. Descriptive analysis of the responses was performed.</p></div><div><h3>Results</h3><p>The participation rate reached 30%, with a total of 135 residents. The 52% of respondents lacked access to a robotic system in their institution, of which only 48% could compensate for this deficiency through external rotations. Among those with access to a robotic system, 25% and 23% reported having access to theoretical and practical training, respectively. The existence of a formal training program was low (13%) and 85% of the respondents considered robotic surgery training in Spain to be deficient.</p></div><div><h3>Conclusions</h3><p>Training for Spanish residents in robotic urological surgery is perceived as inadequate, emphasizing the crucial need for improvement in training programs in this field.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 545-551"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

¿Por qué es necesario tener una cepa de BCG fabricada en España? 为什么必须在西班牙生产 bcg 菌株？

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.01.006

引用次数: 0

Prevalencia y manejo de la incontinencia urinaria asociada a cirugía de prolapso órgano pélvico (colposacropexia). Revisión de la literatura 与盆腔器官脱垂手术（COLPOSACROPEXY）相关的尿失禁的发生率和处理。文献综述

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2023.11.005

{"title":"Prevalencia y manejo de la incontinencia urinaria asociada a cirugía de prolapso órgano pélvico (colposacropexia). Revisión de la literatura","authors":"","doi":"10.1016/j.acuro.2023.11.005","DOIUrl":"10.1016/j.acuro.2023.11.005","url":null,"abstract":"<div><h3>Introduction</h3><p>Stress urinary incontinence (SUI) is frequently associated with pelvic organ prolapse (POP) and may occur after its surgical treatment.</p></div><div><h3>Aim</h3><p>To determine the incidence, risk factors and management of SUI during and after POP surgery through a review of the available literature.</p></div><div><h3>Materials and method</h3><p>Narrative literature review on the incidence and management of SUI after POP surgery after search of relevant manuscripts indexed in PubMed, EMBASE and Scielo published in Spanish or English between 2013-2023.</p></div><div><h3>Results</h3><p>Occult SUI is defined as visible urine leakage when prolapse is reduced in patients without SUI symptoms. De novo SUI develops after prolapse surgery without having previously existed. In continent patients, the number needed to treat (NNT) to prevent one case of de novo SUI is estimated to be 9 patients and about 17 to avoid repeat incontinence surgery. In patients with occult UI, the NNT to avoid repeat incontinence surgery is around 7. Patients with POP and concomitant SUI are the group most likely to benefit from combined surgery with a more favorable NNT (NNT2).</p></div><div><h3>Conclusion</h3><p>Quality studies on combined surgery for treatment SUI and POP repair are lacking. Continent patients with prolapse should be warned of the risk of de novo SUI, although concomitant incontinence treatment is not currently recommended. Incontinence surgery should be considered on an individual basis in patients with prolapse and SUI.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 490-496"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139193931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Manejo conservador del traumatismo renal de alto grado 高位肾创伤的保守治疗

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.01.001

{"title":"Manejo conservador del traumatismo renal de alto grado","authors":"","doi":"10.1016/j.acuro.2024.01.001","DOIUrl":"10.1016/j.acuro.2024.01.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Renal trauma is the most common of urological trauma and accounts for up to 5% of all. The AAST scale is the most widely used to assess renal trauma. This study focuses on high-grade trauma, whose treatment has evolved towards a conservative approach, with techniques such as angioembolization. The aim is to describe the evolution in the management of high-grade renal trauma in all patients treated at La Paz University Hospital from 2001 to 2022.</p></div><div><h3>Material and methods</h3><p>A descriptive retrospective study was conducted on patients treated at the hospital. The study was divided into two periods (2001-2010 and 2011-2022). A total of 285 patients with renal trauma were collected, of which 54 were high grade. The main variable is the type of management, conservative (embolization) or interventional through nephrectomy.</p></div><div><h3>Results</h3><p>In the completed series, there was a decrease in radical nephrectomy in high-grade renal trauma from 50% to 13.8% over time, with an increase in embolization from 23.1% to 44.8%. In patients with isolated renal trauma, those treated with embolization increased from 28.6% to 69.2%, while those undergoing radical/partial nephrectomy decreased from 42.8% to 7.69%.</p></div><div><h3>Conclusion</h3><p>The management of renal trauma has evolved over the years in our center. The number of patients treated by embolization has increased, while the number of complications and nephrectomies has decreased.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 521-525"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139539123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resultados quirúrgicos en mujeres diagnosticadas de endometriosis profunda con afectación urológica 被诊断为泌尿系统受累的深部子宫内膜异位症妇女的手术治疗效果

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2024.02.002

{"title":"Resultados quirúrgicos en mujeres diagnosticadas de endometriosis profunda con afectación urológica","authors":"","doi":"10.1016/j.acuro.2024.02.002","DOIUrl":"10.1016/j.acuro.2024.02.002","url":null,"abstract":"<div><h3>Introduction</h3><p>The prevalence of endometriosis is estimated to be about 10% among women of reproductive age. In about 5-10% of these patients, involvement of urological structures will be developed due to deep endometriosis. Urologists should be familiar with the management of these patients, who will require multidisciplinary care with medical and surgical treatment.</p></div><div><h3>Material and methods</h3><p>Retrospective study of patients diagnosed with deep endometriosis involving urological structures who underwent surgery performed jointly with gynecology and colorectal surgery departments from June 2012 until June 2021 (60 cases). Urologic symptoms were grouped into 3 groupers for subsequent analysis (storage symptoms, voiding symptoms, and low back pain).</p></div><div><h3>Results</h3><p>Storage symptoms (frequency and urgency) are the most frequent urologic symptoms. Patients with storage symptoms and low back pain showed improvement after surgery. In contrast, patients with voiding symptoms did not improve with surgical treatment.</p></div><div><h3>Conclusions</h3><p>The prevalence of endometriosis and the likelihood of involving urologic structures require the urologic community to be aware of the pathology.</p><p>Patients with storage symptoms will improve following excision of the endometriotic nodules. The need for Partial cystectomies with ureteral reimplantation can be safely performed by laparoscopic or robotic approach, even in previously operated patients, without compromising long-term function.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 532-537"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140273983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

¿Por qué los pacientes con derivaciones urinarias tienen un mayor riesgo de fractura ósea? Revisión sistemática sobre los factores de riesgo de osteoporosis y pérdida de densidad mineral ósea en este grupo de pacientes 为什么尿路改道患者的骨折风险会增加？关于该类患者骨质疏松症和骨矿物质密度下降风险因素的系统回顾。

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuro.2023.11.007

{"title":"¿Por qué los pacientes con derivaciones urinarias tienen un mayor riesgo de fractura ósea? Revisión sistemática sobre los factores de riesgo de osteoporosis y pérdida de densidad mineral ósea en este grupo de pacientes","authors":"","doi":"10.1016/j.acuro.2023.11.007","DOIUrl":"10.1016/j.acuro.2023.11.007","url":null,"abstract":"<div><h3>Introduction</h3><p>Patients undergoing radical cystectomy with urinary diversions (UDs) are at increased risk of bone fractures compared to the general population. Although a loss of bone mineral density (BMD) has been described in patients with UDs, we still do not know with certainty why these patients follow this tendency.</p></div><div><h3>Objective</h3><p>We performed a systematic review of the available literature to analyze the prevalence of osteoporosis and bone alterations in patients with ileal UD and the possible associated risk factors.</p></div><div><h3>Evidence acquisition</h3><p>We systematically searched PubMed® and Cochrane Library for original articles published before December 2022 according to PRISMA guidelines.</p></div><div><h3>Evidence synthesis</h3><p>A total of 394 publications were identified. We selected 12 studies that met the inclusion criteria with 496 patients included. Six of the twelve studies showed decreased BMD values. Prevalence of osteoporosis was specified in three articles, with values ranging from 0% to 36%. Risk factors such as age, sex, body mass index, metabolic acidosis and renal function appear to have an impact on bone tissue reduction, while type of UD, follow-up, 25-hydroxyvitaminD and parathormone had less evidence or contradictory data. The heterogeneity of the studies analyzed could led to interpretation bias.</p></div><div><h3>Conclusions</h3><p>UDs are associated with multiple risk factors for osteoporosis and bone fractures. Identifying patients at highest risk and establishing diagnostic protocols in routine clinical practice are essential to reduce the risk of fractures and the resulting complications.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 7","pages":"Pages 497-511"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139191686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tasa de fluctuación del PSA: un indicador prometedor para el cribado del cáncer de próstata PSA 波动率：前列腺癌筛查的一个有前途的指标

IF 1.2 4区医学

Actas urologicas espanolas Pub Date : 2024-07-01 DOI: 10.1016/j.acuro.2023.11.008

U. Can , A. Coskun , C. Canakci , B. Simsek , Y. Karaca , K. Sabuncu , O. Akca

{"title":"Tasa de fluctuación del PSA: un indicador prometedor para el cribado del cáncer de próstata","authors":"U. Can , A. Coskun , C. Canakci , B. Simsek , Y. Karaca , K. Sabuncu , O. Akca","doi":"10.1016/j.acuro.2023.11.008","DOIUrl":"10.1016/j.acuro.2023.11.008","url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate whether PSA fluctuation can be used to predict the risk of prostate cancer.</p></div><div><h3>Materials and methods</h3><p>The study included 1244 patients who underwent prostate biopsy at Kartal Dr. Lutfi Kirdar City Hospital between 2013 and 2021 (848 in non-cancer; 396 in cancer). The patient's age, last two PSA values (PSA<sub>1</sub> and PSA<sub>2</sub>) within three months before the biopsy, the duration between two PSAs (days), prostate size (g) and PSA density (PSAD) were all recorded. PSA fluctuation rate (PSAfr) was defined as the change rate between two PSA values.</p></div><div><h3>Results</h3><p>PSAfr was significantly higher in the non-cancer group than in the prostate cancer group (15.2% [20.5] and 9.6% [14.4], <em>P</em>  =.019). The odds ratio, adjusted for age, PSAD, and PSA2, was calculated as 0.545 (0.33-0.89) using logistic regression analysis to show the relationship between prostate cancer and PSAfr. As a result, those with high PSAfr were found to be 1.83 times less likely to be diagnosed with prostate cancer than those with low fluctuations.</p></div><div><h3>Conclusion</h3><p>PSAfr could be used in nomograms to predict prostate cancer risk and reduce the number of unnecessary biopsies.</p></div>","PeriodicalId":7145,"journal":{"name":"Actas urologicas espanolas","volume":"48 6","pages":"Pages 470-475"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139187826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0