Acta Chimica Slovenica最新文献_第8页

Aaptamine, Promotes Cell Cycle Arrest and Induces Necrotic Cell Death of Colorectal Cancers, Isolated from the Bunaken National Park's Sponge, Aaptos sp. 从布纳肯国家公园的海绵中分离出的Aaptos sp，促进结直肠癌细胞周期阻滞和诱导坏死细胞死亡。

IF 1.3 4区化学

Acta Chimica Slovenica Pub Date : 2024-12-02 DOI: 10.17344/acsi.2024.8779

Annisa Elcentia Fajarwati, Mutia Hardhiyuna, Febby Nurdiya Ningsih, Adam Hermawan, Dyaningtyas Dewi Pamungkas Putri, Nurul Fatimah, Asep Bayu, Andi Setiawan, Ucu Yanu Arbi, Tutik Murniasih, A'liyatur Rosyidah, Tri Aryono Hadi, Masteria Yunovilsa Putra, Peni Ahmadi

引用次数: 0

Synthesis of Schiff Bases of Usnic Acid and Investigation of Their Antidiabetic, Antidepressant, Anti-Parkinson's, Neuroprotective and Antioxidant Potentials. 枸杞酸席夫碱的合成及其抗糖尿病、抗抑郁、抗帕金森、神经保护和抗氧化活性的研究

IF 1.3 4区化学

Acta Chimica Slovenica Pub Date : 2024-11-23 DOI: 10.17344/acsi.2024.8703

Lawali Yabo Dambagi, Ahmet Cakir, Mehmet Akyuz, Ayşegül İyidogan, Ali Aslan

{"title":"Synthesis of Schiff Bases of Usnic Acid and Investigation of Their Antidiabetic, Antidepressant, Anti-Parkinson's, Neuroprotective and Antioxidant Potentials.","authors":"Lawali Yabo Dambagi, Ahmet Cakir, Mehmet Akyuz, Ayşegül İyidogan, Ali Aslan","doi":"10.17344/acsi.2024.8703","DOIUrl":"https://doi.org/10.17344/acsi.2024.8703","url":null,"abstract":"Schiff bases have various pharmacological activities due to the azomethine (-C=N-) group. Usnic acid is the most famous lichen metabolite and it contains two carbonyl groups to synthesize the Schiff base derivatives with primary amines. Therefore, in the current study, the known Schiff base derivatives (2-5) of usnic acid (1) were synthesized to explore their antidiabetic, neuroprotective, antioxidant, antidepressant and anti-Parkinson's properties. Among the tested compounds, compound 4 exhibited the strongest antidiabetic and antidepressant activities, inhibiting α-glycosidase, α-amylase and MAO-A enzyme activities, respectively. Moreover, all of the tested compounds strongly scavenged the ABTS and DPPH radicals and the ABTS radical scavenging activities of 3 and 4 were found to be higher than the commercial antioxidants BHA and trolox. All of the tested compounds did not show any significant anti-Parkinson's and neuroprotective activities. In conclusion, compound 4 can be suggested as a drug candidate molecule for further studies due to its strong antioxidant, antidiabetic and antidepressant properties.","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"71 4","pages":"566-579"},"PeriodicalIF":1.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparation, characterization and theoretical calculation of a cadmium complex of 3-hydroxy-2-methylquinolin-4-carboxylate and 1, 10-phenanthroline. 3-羟基-2-甲基喹啉-4-羧酸盐和1,10 -菲罗啉镉配合物的制备、表征和理论计算。

IF 1.3 4区化学

Acta Chimica Slovenica Pub Date : 2024-11-23 DOI: 10.17344/acsi.2024.9004

Ting-Qun Qiu, Zhi-Tao Lu, Zi-Jian He, Zheng-Ping Xie, Jin Guo, Xiu-Guang Yi

引用次数: 0

Investigation of the composition space diagram CuCl-allylamine-dabco. A new mixed ligand compound of (H2dabco)2[Cu4Cl9(allNH3)] composition with unique Cu4Cl95- cupro(I)-chloride fragment. cucl -烯丙胺-dabco组成空间图的研究。一种新的混合配体化合物（H2dabco）2[Cu4Cl9(allNH3)]组成，具有独特的Cu4Cl95- cupro(I)-chloride片段。

IF 1.3 4区化学

Acta Chimica Slovenica Pub Date : 2024-11-21 DOI: 10.17344/acsi.2024.9005

Evgeny Goreshnik, Olha Panteleieva

引用次数: 0

DRUŠTVENE VESTI IN DRUGE AKTIVNOSTI SOCIETY NEWS, ANNOUNCEMENTS, ACTIVITIES. društvene vesti in druge aktivnosti 社会新闻、公告和活动。

IF 1.2 4区化学

Acta Chimica Slovenica Pub Date : 2024-09-20

引用次数: 0

Synthesis of (E)-3-{[2-oxo-5-arylfuran-3(2H)-ylidene]methyl}-4H-1-benzopyran-4-ones, crystal structure, quantum chemical substantiation. (E)-3-{[2-氧代-5-芳基呋喃-3(2H)-亚基]甲基}-4H-1-苯并吡喃-4-酮的合成、晶体结构和量子化学证据。

IF 1.2 4区化学

Acta Chimica Slovenica Pub Date : 2024-09-12 DOI: 10.17344/acsi.2024.8791

Ekaterina Arzyamova, Olga Mazhukina, Alevtina Yegorova

引用次数: 0

Extraction System for the Spectrophotometric Determination of Tungsten(VI) with 4-Nitrocatechol and Benzalkonium Chloride. 用 4-硝基邻苯二酚和苯扎氯铵分光光度法测定钨(VI)的萃取系统。

IF 1.2 4区化学

Acta Chimica Slovenica Pub Date : 2024-09-10 DOI: 10.17344/acsi.2024.8835

Vidka Vassileva Divarova, Kirila Trifonova Stojnova, Ivelina Dobromirova Radkovska, Antoaneta Dimitrova Saravanska, Galya Kostadinova Toncheva, Vassil Borisov Delchev, Kiril Blazhev Gavazov

{"title":"Extraction System for the Spectrophotometric Determination of Tungsten(VI) with 4-Nitrocatechol and Benzalkonium Chloride.","authors":"Vidka Vassileva Divarova, Kirila Trifonova Stojnova, Ivelina Dobromirova Radkovska, Antoaneta Dimitrova Saravanska, Galya Kostadinova Toncheva, Vassil Borisov Delchev, Kiril Blazhev Gavazov","doi":"10.17344/acsi.2024.8835","DOIUrl":"https://doi.org/10.17344/acsi.2024.8835","url":null,"abstract":"A novel chromogenic system for the liquid-liquid extraction and determination of trace amounts of tungsten(VI) was investigated. The system comprises 4-nitrocatechol (4NC) as a chromogenic reagent, sulfuric acid as a complexing medium, and benzalkonium chloride (BAC) as a source of bulky cations (BA+), which readily form chloroform-extractable ion-association complexes. The impact of foreign ions and reagents was studied, and the optimal conditions for the sensitive, selective, and inexpensive determination of tungsten(VI) were identified. The limit of detection, linear working range, and molar absorptivity at lmax (422 nm) were determined to be 31 ng cm-3, 0.1-4.4 µg cm-3, and 5.49 × 104 dm3 mol-1 cm-1, respectively. The composition of the extracted complex was 1:2:2 (W:4NC:BA). Two potential structures of its anionic component, [WO2(4NC)2]2-, were discussed based on optimizations at the B3LYP/CEP-4G theoretical level and comparison between theoretical and experimental spectra.","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"71 3","pages":"519-527"},"PeriodicalIF":1.2,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthetic optimization and antibacterial activity of novel benzodioxepine-biphenyl amide derivatives. 新型苯并二氧杂环庚烷-联苯酰胺衍生物的合成优化和抗菌活性。

IF 1.2 4区化学

Acta Chimica Slovenica Pub Date : 2024-08-31 DOI: 10.17344/acsi.2024.8784

Shao-Peng Yan, Zhi-Yu Zhu, Qi-Ke Jia, Rui-Ying Ji, Ya-Pin Wang, Dan He, Rong Wang, Yang Zhou

引用次数: 0

Phytochemical analysis and evaluation of the antioxidant, anti-inflammatory, hemolytic, and antibacterial effects of Astragalus gombo (L.) leaves. 黄芪（L.）叶的植物化学分析及抗氧化、抗炎、溶血和抗菌效果评估

IF 1.2 4区化学

Acta Chimica Slovenica Pub Date : 2024-08-27 DOI: 10.17344/acsi.2024.8748

Mohammed Laid Tlili, Ibtissam Laib, Khadidja Salemi, Imane Chetehouna, Ines Ben Moussa

{"title":"Phytochemical analysis and evaluation of the antioxidant, anti-inflammatory, hemolytic, and antibacterial effects of Astragalus gombo (L.) leaves.","authors":"Mohammed Laid Tlili, Ibtissam Laib, Khadidja Salemi, Imane Chetehouna, Ines Ben Moussa","doi":"10.17344/acsi.2024.8748","DOIUrl":"10.17344/acsi.2024.8748","url":null,"abstract":"The purpose of this study is to determine the phytochemical content and biological activities of the Astragalus gombo (endemic specie). While identification and quantification of individual secondary metabolites were performed by analysis HPLC. Antioxidant (DPPH and FRAP), anti-inflammatory, anti-hemolytic and antibacterial activities were evaluated. For analysis HPLC, we obtained 65 peaks and identified 6 major bioactive compounds. The total concentration in polyphenols, flavonoids and condensed tannins varied respectively from 66.306±0.88 mg GA eq/g, 34.312±1.4 mg Q eq/g and 5.343±2.74 mg Ca eq/g. In terms of antioxidant activity, we found that this extract had high inhibitory ratios equivalent to IC50=62.813±0.006 µg/mL for DPPH and IC50=19.375±0.041 µg/mL for FRAP. A high anti-inflammatory activity was estimated at 1615.81µg/mL, and a weak anti-hemolytic activity, the other hand the antibacterial activity is somewhat moderate against the five strains studied. This study demonstrated that the aqueous extract of A. gombo from El Oued region has tremendous antioxidant, anti-inflammatory and antibacterial abilities.","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"71 3","pages":"492-499"},"PeriodicalIF":1.2,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of high-resolution continuum source flame atomic absorption spectrometry for determination of selected toxic and potential toxic metals in the decontamination process of wastewater discharged in natural receivers. 验证高分辨率连续源火焰原子吸收光谱法测定天然接收器中排放的废水净化过程中的特定有毒和潜在有毒金属。

IF 1.2 4区化学

Acta Chimica Slovenica Pub Date : 2024-08-27 DOI: 10.17344/acsi.2023.8534

Bame Sanah Senna, Wellington Masamba, Veronica Obuseng, Tiberiu Frentiu, Bogdan Simion Angyus, Eniko Covaci

{"title":"Validation of high-resolution continuum source flame atomic absorption spectrometry for determination of selected toxic and potential toxic metals in the decontamination process of wastewater discharged in natural receivers.","authors":"Bame Sanah Senna, Wellington Masamba, Veronica Obuseng, Tiberiu Frentiu, Bogdan Simion Angyus, Eniko Covaci","doi":"10.17344/acsi.2023.8534","DOIUrl":"https://doi.org/10.17344/acsi.2023.8534","url":null,"abstract":"A new method based on high-resolution continuum source flame atomic absorption spectrometry (HR-CS-FAAS) was validated for the determination of selected toxic and potentially toxic metals in wastewater resulting from mining activity. The results were compared with inductively coupled plasma optical emission spectrometry (ICP-OES). The HR-CS-FAAS method was characterized by detection limits in the range (µg L-1) 0.9(Mn)-33.6(Pb), better than ICP-OES for Cu, Fe, Ni, Co, Pb and Mn, and poorer for Cd, Zn and Cr. The Dunnett's and Tukey's statistical test showed that both methods were not affected by significant bias against certified value and between them. The recovery in HR-CS-FAAS method was in the range of 98-103% with relative extended uncertainty of 9-25%, and precision of 1.5-14.1%. The results indicated that the HR-CS-FAAS method is suitable for the determination of toxic and potentially toxic elements directly in filtered water samples without any chemical treatment.","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"71 3","pages":"500-508"},"PeriodicalIF":1.2,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0