Acta clinica Croatica最新文献_第3页

THE IMPACT OF ENDODONTIC STATUS ON QUALITY OF LIFE. 牙髓状态对生活质量的影响。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.13

Petra Dijanić, Ana Ivanišević, Silvana Jukić Krmek, Jelena Perica Pavešić, Zoran Karlović, Jurica Matijević

{"title":"THE IMPACT OF ENDODONTIC STATUS ON QUALITY OF LIFE.","authors":"Petra Dijanić, Ana Ivanišević, Silvana Jukić Krmek, Jelena Perica Pavešić, Zoran Karlović, Jurica Matijević","doi":"10.20471/acc.2024.63.03-04.13","DOIUrl":"10.20471/acc.2024.63.03-04.13","url":null,"abstract":"The influence of endodontic status on quality of life has not been fully clarified. The aim of this study was to quantify the effect of endodontic status on everyday functioning using the psychometric instrument Oral Impacts on Daily Performances (OIDP) and to correlate endodontic status with quality of life using the OIDP questionnaire. A total of 600 participants were referred to dental radiography for digital orthopantomograms and asked to fill out the OIDP questionnaire. Digital orthopantomograms were analyzed and compared with OIDP results. The correlation between endodontic status and quality of life was tested. The statistical analysis consisted of descriptive statistics, non-parametric statistics, hierarchical multiple regression analysis by enter method, and correlation analysis. The results showed that quality of life was significantly affected by tooth loss (p<0.05). Endodontic treatment on canines and incisors positively correlated with higher OIDP scores, indicating an effect on quality of life (p<0.05). In conclusion, the correlations between variables describing the endodontic status and the quantitative results of the OIDP questionnaire indicate a measurable effect of endodontic disease/health on everyday functioning.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"552-559"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

LYMPHOSCINTIGRAPHY IN LYMPHEDEMA. 淋巴水肿的淋巴显像。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.24

Igor Iskra, Tatjana Bogović Crnčić, Neva Girotto

引用次数: 0

RHEOLOGICAL PARAMETERS OF CAROTID CIRCULATION IN METABOLIC SYNDROME WITH OR WITHOUT DIABETES MELLITUS. 伴有或不伴有糖尿病的代谢综合征患者颈动脉循环流变学参数。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.25

Alen Hajdarević, Dragan Piljić, Fahrudin Šabanović, Dilista Piljić, Farisa Babić, Ajdin Beganović, Juš Kšela

{"title":"RHEOLOGICAL PARAMETERS OF CAROTID CIRCULATION IN METABOLIC SYNDROME WITH OR WITHOUT DIABETES MELLITUS.","authors":"Alen Hajdarević, Dragan Piljić, Fahrudin Šabanović, Dilista Piljić, Farisa Babić, Ajdin Beganović, Juš Kšela","doi":"10.20471/acc.2024.63.03-04.25","DOIUrl":"10.20471/acc.2024.63.03-04.25","url":null,"abstract":"The aim of this research was to examine the rheological parameters of carotid arteries and the frequency of abnormal values in patients with metabolic syndrome (MetS) with and without diabetes mellitus (DM). The sample consisted of 90 subjects and was divided into two equal groups. The first group consisted of patients with MetS but without DM, while the second group had both MetS and DM. We used the values of the peak systolic velocity (PSV) as a reference for pathology. The results showed pathological values of PSV in the right internal carotid artery (ICA) in twelve patients in the MetS + DM group. The study found that the incidence of pathological rheological parameters was higher in subjects with MetS + DM as compared to those with only MetS. Subjects with MetS + DM had higher values of maximum acceleration during systole in various carotid arteries. A subject with MetS + DM also showed total flow obstruction in the left and internal carotid artery (ICA) and a severe narrowing of the right ICA, indicating the presence of carotid artery disease. The study also found that nearly two-thirds of subjects with MetS + DM had pathological values of PSV in the right ICA and slightly fewer in the left ICA. Research on French populations has shown similar results. Eleven patients had pathological values in the left ICA. The frequency of the carotid rheological parameters' abnormalities was significantly higher in the MetS with DM patient group. The frequency of abnormalities in the rheological parameters of carotid circulation was significantly higher in patients with MetS and DM (as compared to non-diabetic patients). In our study, pathological changes were generally more susceptible to ICA. This indicates the importance of screening the rheological parameters of subjects with MetS for the prevention and treatment of cerebrovascular disease.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"656-661"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ENDOSCOPIC RECTAL ULTRASOUND IN RECTAL ADENOCARCINOMA STAGING: CAN A SURGEON RELY ON ENDOSCOPIC FINDINGS BEFORE THE SURGERY? - COMPARISON WITH POSTOPERATIVE PATHOLOGICAL DIAGNOSIS. 内镜直肠超声在直肠腺癌分期中的应用：外科医生在手术前能否依赖内镜检查结果？-与术后病理诊断比较。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.09

Melanija Ražov Radas, Nataša Lisica Šikić

{"title":"ENDOSCOPIC RECTAL ULTRASOUND IN RECTAL ADENOCARCINOMA STAGING: CAN A SURGEON RELY ON ENDOSCOPIC FINDINGS BEFORE THE SURGERY? - COMPARISON WITH POSTOPERATIVE PATHOLOGICAL DIAGNOSIS.","authors":"Melanija Ražov Radas, Nataša Lisica Šikić","doi":"10.20471/acc.2024.63.03-04.09","DOIUrl":"10.20471/acc.2024.63.03-04.09","url":null,"abstract":"Our aim in this study was to demonstrate the usefulness of endoscopic rectal ultra- sound scan (ERUS) in providing information that can help surgeons decide on therapeutic approach and type of surgical procedure in patients with rectal cancer. We compared ERUS findings with postoperative pathological data in 41 patients with endoscopic and pathological (PH) diagnosis of rectal cancer. These patients underwent ERUS examination to determine the extent of the disease and the findings were subsequently compared with postoperative pathological diagnosis. After ERUS examination, there were three patients in group T0, five in group T1, 12 in group T2, 17 in group T3, two in group T4, and two patients had a mucinous metastatic type of cancer. After excluding 15 patients who met the exclusion criteria, we compared ERUS findings of 26 patients with their pathological diagnosis to determine the sensitivity and accuracy of ERUS. The total sensitivity of the ERUS in preoperative staging of the tumor stage T0-T4 was 96%. Accuracy was 89%. This study showed that a surgeon can rely on the findings of ERUS performed by an experienced endoscopist before deciding of type of surgical procedure for T0-T2, and even T3 degree of rectal cancer. T3 rectal cancers are in the \"gray zone\", so both procedures, ERUS and nuclear magnetic resonance imaging (NMR), are needed to decide on the final therapeutic approach. NMR remains the gold standard for staging T4 rectal cancer.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"518-522"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DIAGNOSTIC VALUE OF STIMULATED SERUM THYROGLOBULIN IN THE FOLLOW-UP OF PATIENTS WITH DIFFERENTIATED THYROID CANCER. 血清促甲状腺球蛋白在分化型甲状腺癌随访中的诊断价值。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.02

Vlado Wagenhofer, Ivan Mihaljević, Tatjana Kralj, Dubravka Vrdoljak, Tomislav Kizivat

{"title":"DIAGNOSTIC VALUE OF STIMULATED SERUM THYROGLOBULIN IN THE FOLLOW-UP OF PATIENTS WITH DIFFERENTIATED THYROID CANCER.","authors":"Vlado Wagenhofer, Ivan Mihaljević, Tatjana Kralj, Dubravka Vrdoljak, Tomislav Kizivat","doi":"10.20471/acc.2024.63.03-04.02","DOIUrl":"10.20471/acc.2024.63.03-04.02","url":null,"abstract":"The aim was to determine the diagnostic value of stimulated serum thyroglobulin (sTg) for the follow-up of patients with differentiated thyroid cancer (DTC) and to evaluate whether repeated sTg measurement provides additional clinical benefit in detecting persistent or recurrent structural disease if the initial sTg was negative. The retrospective study included 388 consecutive patients with DTC treated and followed-up between 2004 and 2018 at the Clinical Institute of Nuclear Medicine and Radiation Protection, Osijek University Hospital. The negative predictive value (NPV) of the first sTg measured 12 months after the initial treatment was compared with NPV of sTg measured annually during 3 consecutive years of follow-up. The first sTg NPV was 99.5% in the group of low-risk patients and 96.1% in the group of intermediate-risk patients. In both low-and intermediate-risk groups, there were no differences between the first sTg NPV and NPV of sTg measured annually during 3 years of follow-up period. Repeated measurement of the sTg after initially negative result had a limited clinical value for detecting persistent or recurrent structural disease and cannot be recommended in routine follow-up of low and intermediate-risk patients with DTC.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"468-474"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CORRELATION BETWEEN VISUAL FIELD SENSITIVITY AND RETINAL NERVE FIBER LAYER THICKNESS IN UNILATERAL EXFOLIATION SYNDROME. 单侧剥脱综合征患者视野敏感度与视网膜神经纤维层厚度的关系。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.04

Marija Šimić Prskalo, Zrinko Prskalo, Željka Tomić, Teo Tomić

{"title":"CORRELATION BETWEEN VISUAL FIELD SENSITIVITY AND RETINAL NERVE FIBER LAYER THICKNESS IN UNILATERAL EXFOLIATION SYNDROME.","authors":"Marija Šimić Prskalo, Zrinko Prskalo, Željka Tomić, Teo Tomić","doi":"10.20471/acc.2024.63.03-04.04","DOIUrl":"10.20471/acc.2024.63.03-04.04","url":null,"abstract":"This study aimed to evaluate retinal nerve fiber layer thickness in exfoliation syndrome (XFS), present unilaterally, using optical coherence tomography (OCT). This prospective study included 90 examinees with unilateral syndrome. However, examinees with higher intraocular pressure or findings implicative of glaucoma were excluded from the study, as well as examinees with optic nerve changes. In individuals with unilateral XFS, OCT findings were compared between the two groups: the affected eye group and the fellow eye group. The study results show that the average thinning of the retinal nerve fiber layer, especially in the inferior and superior quadrants, has not resulted in visual field defects in examinees with unilateral XFS. In the group of eyes without XFS, 85.55% exhibited reference inferior quadrant thickness values, and 91.11% exhibited reference superior quadrant thickness values. In the group of eyes with manifest XFS, 82.22% exhibited reference inferior quadrant thickness values, and 88.88% exhibited reference superior quadrant thickness values. Most examinees in both groups had normal average retinal nerve fiber layer (RNFL) thickness (72.22%). In examinees with clinically unilateral XFS, RNFL thinning occurs in both eyes before XFS becomes bilateral and before hypertensive intraocular pressure can be measured.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"482-486"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PERCUTANEOUS CORONARY INTERVENTION ON SAPHENOUS VEIN GRAFT IN SECOND GENERATION DRUG ELUTING STENT ERA. 第二代药物洗脱支架时代隐静脉移植物经皮冠状动脉介入治疗。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.20

Milenko Čanković, Andrej Preveden, Vladimir Ivanović, Aleksandra Milovančev, Milovan Petrović, Mila Kovačević, Tatjana Miljković, Marija Bjelobrk, Lazar Velicki

{"title":"PERCUTANEOUS CORONARY INTERVENTION ON SAPHENOUS VEIN GRAFT IN SECOND GENERATION DRUG ELUTING STENT ERA.","authors":"Milenko Čanković, Andrej Preveden, Vladimir Ivanović, Aleksandra Milovančev, Milovan Petrović, Mila Kovačević, Tatjana Miljković, Marija Bjelobrk, Lazar Velicki","doi":"10.20471/acc.2024.63.03-04.20","DOIUrl":"10.20471/acc.2024.63.03-04.20","url":null,"abstract":"The aim of the study was to determine major adverse cardiac events (MACE) related to the percutaneous coronary intervention (PCI) on saphenous vein graft (SVG) with a second-generation drug eluting stents in patients with previous coronary artery bypass graft (CABG). The research was conducted as a unicenter retrospective observational study which analyzed consecutive patients of both genders who had PCI on SVG from January 1, 2016 until June 30, 2019. The aim was to investigate the occurrence of MACE defined as development of periprocedural myocardial infarction, acute heart failure in the first 24 hours after PCI, unstable angina after PCI, periprocedural stroke, contrast induced nephropathy, death, acute/subacute/late stent thrombosis, and target lesion revascularization. The study included 97 consecutive patients. MACE was recorded in 20.6% of patients, more often in patients with thrombolysis in myocardial infarction grade flow ≤2. High thrombus burden (HTB) was detected in 44.3% of patients and it significantly contributed to the development of MACE. In conclusion, PCI on SVG is a highly challenging procedure, especially in patients with an acute coronary syndrome. In patients who have HTB recorded in SVG, the usage of thrombus aspiration and distal protection device can reduce the frequency of no-reflow phenomenon and consequential MACE.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"611-618"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PRENATAL AND OBSTETRIC RISK FACTORS FOR DEVELOPMENT OF DISABILITIES IN CHILDHOOD. 儿童残疾发展的产前和产科风险因素。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.27

Ksenija Romstein, Dubravko Habek, Tena Velki, Maja Košuta Petrović

{"title":"PRENATAL AND OBSTETRIC RISK FACTORS FOR DEVELOPMENT OF DISABILITIES IN CHILDHOOD.","authors":"Ksenija Romstein, Dubravko Habek, Tena Velki, Maja Košuta Petrović","doi":"10.20471/acc.2024.63.03-04.27","DOIUrl":"10.20471/acc.2024.63.03-04.27","url":null,"abstract":"The main objective was to analyze prenatal and obstetric risk factors in relation to the development of disabilities. For that purpose, data on medication, i.e., use of benzodiazepines during pregnancy, gestational weeks, mode of delivery (vaginal or cesarean section), duration of delivery, and fetal presentation were retrieved from medical records and semi-structured interviews with mothers/legal guardians. Trained professionals clinically assessed the children's developmental status (N=107). Fisher exact test with post hoc analysis of standardized residuals showed that a statistically significant number of children with multiple disabilities were born by cesarean section (z=3.7, p<0.001), prematurely (z=4.8, p<0.001), and by mothers using benzodiazepines (z=2.6, p<0.01). Children with autism spectrum disorders were more often delivered post-term (z=2.0, p<0.05) by induced delivery (z=2.9, p<0.01). Children with developmental coordination disorder were more often born post-term (z=2.2, p<0.05). As for the duration of delivery and fetal presentation, there was no statistically significant correlation with developmental disabilities. There is a cumulative risk of developmental disabilities rather than just a single risk factor. More interdisciplinary and longitudinal research on developmental disabilities, including children's educational outcomes should be conducted.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"670-677"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PROGNOSTIC VALUE OF TUMOR BUDDING IN SPORADIC COLORECTAL CANCER STAGE II PATIENTS WITH A LOW NUMBER OF LYMPH NODES EXAMINED. 散发性结直肠癌ii期低淋巴结检查患者肿瘤出芽的预后价值。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.37

Josip Baković, Čedna Tomasović-Lončarić, Arijana Pačić, Iva Škifić, Valentin Lisek, Karolina Krstanac, Petra Čičak, Paško Konjevoda

{"title":"PROGNOSTIC VALUE OF TUMOR BUDDING IN SPORADIC COLORECTAL CANCER STAGE II PATIENTS WITH A LOW NUMBER OF LYMPH NODES EXAMINED.","authors":"Josip Baković, Čedna Tomasović-Lončarić, Arijana Pačić, Iva Škifić, Valentin Lisek, Karolina Krstanac, Petra Čičak, Paško Konjevoda","doi":"10.20471/acc.2024.63.03-04.37","DOIUrl":"10.20471/acc.2024.63.03-04.37","url":null,"abstract":"Stage II colorectal cancer (CRC) is a major therapeutic challenge because it is not easy to decide whether patients will benefit from adjuvant chemotherapy or not. This study was designed as a retrospective prognostic study combining standard histopathologic parameters with tumor budding and microsatellite instability. The study included 89 patients on elective treatment for stage II primary colorectal adenocarcinoma from January 2011 to December 2015. Study results indicated that the prognosis of patients with stage II CRC depended on the combination of three factors, (in the order of importance): number of lymph nodes examined; total number of buds per 0.785 mm2 (≥5.5); and positive lymphovascular invasion. There is increasing evidence that tumor biology and non-anatomic characteristics are important in the prognosis and treatment of CRC. One of them is tumor budding which is not yet an integral part of the AJCC staging system. A low number of the lymph nodes examined is associated with high-risk patients. All patients without an adequate number of lymph nodes examined (less than 8 lymph nodes) should a priori be considered a very high-risk group, with a very low survival rate, and chemotherapy should be used.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"758-768"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TRANSIENT HYPOPHOSPHATEMIA AS POSSIBLE ADVERSE OUTCOME AFTER IRON DEFICIENCY ANEMIA TREATMENT WITH FERRIC CARBOXYMALTOSE - SINGLE CENTER EXPERIENCE. 用羧麦芽糖铁治疗缺铁性贫血后可能出现的短暂性低磷血症-单中心经验。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2024-12-01 DOI: 10.20471/acc.2024.63.03-04.03

Nikolina Brkić, Ivana Vučinić Ljubičić, Hrvoje Holik, Božena Coha

{"title":"TRANSIENT HYPOPHOSPHATEMIA AS POSSIBLE ADVERSE OUTCOME AFTER IRON DEFICIENCY ANEMIA TREATMENT WITH FERRIC CARBOXYMALTOSE - SINGLE CENTER EXPERIENCE.","authors":"Nikolina Brkić, Ivana Vučinić Ljubičić, Hrvoje Holik, Božena Coha","doi":"10.20471/acc.2024.63.03-04.03","DOIUrl":"10.20471/acc.2024.63.03-04.03","url":null,"abstract":"The aim of this study was to determine the frequency of hypophosphatemia in female patients with iron deficiency anemia (IDA) treated parenterally with ferric carboxymaltose (FCM). Thirty-two female patients examined for IDA at the Hematology and Oncology Department of one General Hospital were included in the study. The inclusion criteria were hemoglobin <110 g/L, transferrin saturation <50%, ferritin <30 ng/mL, and ineffective oral iron therapy. The hemoglobin values were significantly increased 6 weeks after therapy in comparison with initial values. The onset of the asymptomatic hypophosphatemia was observed in 17 of 32 patients two weeks after the FCM therapy. Only one of 32 patients had severe asymptomatic hypophosphatemia (serum phosphate <0.3 mmol/L). Prolonged hypophosphatemia (6 weeks after FCM therapy) was observed in five of 32 patients, of which only one patient had initial hypophosphatemia. The difference between the phosphate values measured two weeks after the FCM therapy and the phosphate values at the first and last follow-up was statistically significant. Serum phosphate values should be routinely measured before and after parenteral FCM therapy.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"475-481"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0