Acta clinica Croatica最新文献_第3页

EXPRESSION OF CONNEXIN-40 AND INTERLEUKIN 6 GENES IN PATIENTS WITH ATRIAL FIBRILLATION. 心房颤动患者连接蛋白40和白细胞介素6基因的表达。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-06-01 DOI: 10.20471/acc.2025.64.02.18

Saima Sharif, Hafsa Ijaz, Saira Rafaqat, Shabina Waris, Shagufta Naz, Aleksandra Klisic

{"title":"EXPRESSION OF CONNEXIN-40 AND INTERLEUKIN 6 GENES IN PATIENTS WITH ATRIAL FIBRILLATION.","authors":"Saima Sharif, Hafsa Ijaz, Saira Rafaqat, Shabina Waris, Shagufta Naz, Aleksandra Klisic","doi":"10.20471/acc.2025.64.02.18","DOIUrl":"10.20471/acc.2025.64.02.18","url":null,"abstract":"Atrial fibrillation (AF) is the outcome of the rapid onset of abnormal electrical impulses in the atria. These impulses prevent the heart natural pacemaker, which normally controls the heart beat, from doing its job.The heart rate becomes highly asymmetric. The purpose of this case-control study was to determine the role of the connexin-40 (Cx-40) and interleukin-6 (IL-6) gene expression in patients suffering from AF in Pakistan. There were 200 subjects included in this study. The subjects were categorized into two groups as control and AF groups (n=100 each). RNA separated from blood was used for analysis of the Cx-40 and IL-6 gene expression by real-time polymerase chain reaction. The Cx-40 gene expression profile was increased 10.2-fold in AF subjects as compared to 1.9-fold in control group. The IL-6 gene expression profile was decreased 1.5-fold in AF group as compared to 6.1-fold in control group. Results of the study suggest that development of AF in the Pakistani population was linked to the increased expression of Cx-40 gene and lower expression of IL-6 gene.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"64 2","pages":"345-353"},"PeriodicalIF":0.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12863287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146111970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE CONNECTION BETWEEN THE EXPERIENCE OF MOBBING, JOB CHARACTERISTICS AND PHYSICAL MANIFESTATIONS AMONG NURSES/TECHNICIANS WORKING IN CHILDREN'S DEPARTMENTS. 儿科护士/技术人员遇袭经历、工作特点与身体表现的关系

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-06-01 DOI: 10.20471/acc.2025.64.02.12

Antun Bajan, Dubravka Matijašić-Bodalec, Antonija Krstačić, Petra Mamić, Slavica Đorđević, Nikola Bajan, Andrea Milostić-Srb, Nika Srb, Vedrana Makarović, Tomislav Kizivat, Irena Habazin

{"title":"THE CONNECTION BETWEEN THE EXPERIENCE OF MOBBING, JOB CHARACTERISTICS AND PHYSICAL MANIFESTATIONS AMONG NURSES/TECHNICIANS WORKING IN CHILDREN'S DEPARTMENTS.","authors":"Antun Bajan, Dubravka Matijašić-Bodalec, Antonija Krstačić, Petra Mamić, Slavica Đorđević, Nikola Bajan, Andrea Milostić-Srb, Nika Srb, Vedrana Makarović, Tomislav Kizivat, Irena Habazin","doi":"10.20471/acc.2025.64.02.12","DOIUrl":"10.20471/acc.2025.64.02.12","url":null,"abstract":"Mobbing (bullying) at the workplace of nurses is a serious problem in the world today. Its manifestations can be very different, from psychological to physical manifestations, and can be related to the onset of post-traumatic stress disorder. The aim of this study was to examine the experience of mobbing at the workplace of pediatric nurses and its connection with physical manifestations. For this purpose, we conducted a study on 434 nurses/technicians in 18 hospitals in the Republic of Croatia. The research instrument consisted of two questionnaires and personal characteristics of the examinees. The examinees were between the ages of 36 and 45, those who had more than 6 years of experience, those who did not work in shifts, who did not work at the job they wanted, and examinees who believed that the conditions at their workplace were threatening their health, and those whose work was the cause of sick leave in the last year. Among the examinees who had experienced mobbing, compared to those who had not, there was a greater number of those who did not evaluate their cooperation with colleagues and their relationship with superiors positively or did not know how to evaluate that relationship. The results obtained with the Physical Symptoms Inventory scale showed that the examinees who had experienced mobbing had a significantly higher incidence of the examined symptoms for which they visited a doctor. In conclusion, nurses employed at children's wards had a positive association of physical manifestations with the experience of mobbing at the workplace, for which preventive programs should be developed to prevent or reduce its occurrence, but also lifelong learning programs should be developed to empower those nurses who currently show symptoms of mobbing.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"64 2","pages":"280-290"},"PeriodicalIF":0.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12863378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A NOVEL SUTURE TECHNIQUE FOR REDUCTION OF A WIDE COLUMELLAR BASE: OUR EXPERIENCE. 一种新颖的缝合技术减少宽小柱基部：我们的经验。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-06-01 DOI: 10.20471/acc.2025.64.02.03

Dubravko Manestar, Marko Velepič, Marica Lidia Mačkić, Daiga Marnauza, Marija Litvinenko, Emanuel Borović

引用次数: 0

CORRELATION OF PHYSICAL AND MENTAL COMPONENTS OF HEALTH-RELATED QUALITY OF LIFE, FUNCTION AND PAIN IN PATIENTS WITH CHRONIC NONSPECIFIC LOW BACK PAIN. 慢性非特异性腰痛患者与健康相关的生活质量、功能和疼痛的身心成分的相关性

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-06-01 DOI: 10.20471/acc.2025.64.02.09

Mirjana Berković-Šubić, Simeon Grazio, Gilbert Hofmann, Zoran Zoričić

{"title":"CORRELATION OF PHYSICAL AND MENTAL COMPONENTS OF HEALTH-RELATED QUALITY OF LIFE, FUNCTION AND PAIN IN PATIENTS WITH CHRONIC NONSPECIFIC LOW BACK PAIN.","authors":"Mirjana Berković-Šubić, Simeon Grazio, Gilbert Hofmann, Zoran Zoričić","doi":"10.20471/acc.2025.64.02.09","DOIUrl":"10.20471/acc.2025.64.02.09","url":null,"abstract":"Health-related quality of life (HRQoL) is significantly reduced in patients with chronic nonspecific low back pain. In these patients, the relationship between physical and mental health with quality of life has not been adequately studied, nor has the relationship between functional disability and pain intensity. The aim of this study was to evaluate the relationship between the physical and mental components of HRQoL and their association with pain intensity and functional disability in patients with better and worse physical and mental health. In addition to sociodemographic and baseline data, disease-specific measures were obtained using standard questionnaires, i.e., the visual analog scale for pain, the Roland-Morris Disability Questionnaire for functional capacity in patients with chronic low back pain, and the Brief Health-Related Quality of Life Questionnaire (SF-36). Statistical significance was determined at p<0.05. The study involved 129 consecutive patients (33 men and 96 women) with chronic low back pain. A significant positive association was found between overall HRQoL, height, and body weight in relation to physical and mental health, but not with body weight in relation to physical health. A negative association was found with age, intensity of movement pain, and functional disability in relation to physical and mental health. An improvement in mental health was found compared to an increase in physical health. Better physical and mental health scores were associated with lower levels of functional disability. In conclusion, the results of this real-life study demonstrated the importance of improving the physical components of HRQoL as it affects assessment of the mental component in patients with chronic low back pain. Moreover, patients with better quality of life rated functional disability lower.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"64 2","pages":"251-260"},"PeriodicalIF":0.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12863285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THROMBOTIC RISK EVALUATION OF TWO METHYLENETETRAHYDROFOLATE REDUCTASE MUTATIONS C677t AND A1298c IN VENOUS THROMBOEMBOLISM. 两种亚甲基四氢叶酸还原酶突变C677t和A1298c在静脉血栓栓塞中的血栓风险评估。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-06-01 DOI: 10.20471/acc.2025.64.02.07

Renata Kundid, Monika Kolundžić, Ivana Babić, Tatjana Kereš, Tomo Svaguša, Jasna Bingulac-Popović, Ana Hećimović, Irena Jukić

{"title":"THROMBOTIC RISK EVALUATION OF TWO METHYLENETETRAHYDROFOLATE REDUCTASE MUTATIONS C677t AND A1298c IN VENOUS THROMBOEMBOLISM.","authors":"Renata Kundid, Monika Kolundžić, Ivana Babić, Tatjana Kereš, Tomo Svaguša, Jasna Bingulac-Popović, Ana Hećimović, Irena Jukić","doi":"10.20471/acc.2025.64.02.07","DOIUrl":"10.20471/acc.2025.64.02.07","url":null,"abstract":"The MTHFR mutations C677T and A1298C combined with folate and vitamin B12 deficiency lead to hypercoagulability. We evaluated thrombotic risk due to MTHFR mutations, individually and in combination, in patients with venous thromboembolism (VTE). The case-control study included groups of 262 VTE patients and 101 healthy controls. Allelic distribution of MTHFR C677T/A1298C mutations was determined by real-time polymerase chain reaction and results were statistically analyzed using χ2-test and comparison of proportions with 95% confidence intervals (95% CI) and p=0.05. There was no statistically significant difference in the frequencies of C677T MTHFR genotypes between the patient group and controls (p=0.676; odds ratio (OR)=1.297; 95% CI 0.649-2.592), or for A1298C mutation (p=0.872; OR=0.894; 95% CI 0.564-1.419). The allele distribution of both MTHFR mutations did not show any significant differences (C677T p=0.808; OR=1.043; 95% CI 0.741-1.468 and A1298C p=0.738; OR=0.943; 95% CI 0.667-1.332). MTHFR genotype distributions did not show any significant difference between genders when analyzed with χ2-test. When evaluating a combination of mutations, the greatest difference between the cases and controls was found in the frequencies of MTHFR TT/AA carriers (2.6%), which, however, did not reach significance (p=0.520). In conclusion, MTHFR C677T and A1298C mutations do not represent risk factors for VTE development in the group of Croatian patients.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"64 2","pages":"233-239"},"PeriodicalIF":0.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12863379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OPTIMIZATION OF HCV CELL CULTURE SYSTEM FOR EVALUATION OF ANTIVIRAL DRUGS AGAINST HCV GENOTYPES 2a AND 4a. HCV细胞培养系统的优化，用于评估抗HCV基因型2a和4a抗病毒药物。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-03-01 DOI: 10.20471/acc.2025.64.01.10

Naiera M Helmy, Reem El-Shenawy, Tawfeek H Abdelhafez, Ashraf A Tabll, Ana Petrović, Elizabeta Horvatić, Martina Smolić, Dominik Gjoni, Robert Smolić

{"title":"OPTIMIZATION OF HCV CELL CULTURE SYSTEM FOR EVALUATION OF ANTIVIRAL DRUGS AGAINST HCV GENOTYPES 2a AND 4a.","authors":"Naiera M Helmy, Reem El-Shenawy, Tawfeek H Abdelhafez, Ashraf A Tabll, Ana Petrović, Elizabeta Horvatić, Martina Smolić, Dominik Gjoni, Robert Smolić","doi":"10.20471/acc.2025.64.01.10","DOIUrl":"10.20471/acc.2025.64.01.10","url":null,"abstract":"Evaluation of hepatitis C virus (HCV) infection in cell culture is important for development of new antiviral agents and for understanding the viral life cycle, as well as the correlation among the genotypes spreading worldwide. Development of HCV cell culture systems offers great advantage by enabling growth of the virus in cell culture, allowing for discovery of potential therapeutics and vaccines. The aim of this study was to introduce the steps of HCV infection in the cell culture system as a determinant for the competence of more potent antiviral compounds. Two plasmids, JFH1 (genotype 2a) full length and 4a (ED43/C-NS2/NS5A) were subjected to in vitro transcription for HCV RNA synthesis followed by transfection of Huh7.5 with the resulting RNA from each genotype processed to generate the virus. Later, Huh7.5 cells infected with the replicated virus resulted in the generated HCV infected cells. Immunostaining of the infected cells showed fluorescence of green color, indicating positive infection of both genotypes 2a and 4a. In addition, real-time polymerase chain reaction was performed to measure viral load from extracted cells previously infected with the RNAs of genotypes 2 and 4, which resulted in 32,500 and 107,375 copies/mL, respectively. In conclusion, introduction of HCV cell culture system is a convenient method to evaluate active antiviral drugs against HCV genotypes 2a and 4a using both qualitative and quantitative techniques in distinguishing the effectiveness of antiviral agents.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"64 1","pages":"93-101"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145666777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SERUM PHOSPHORUS AS A RISK FACTOR FOR CARDIOVASCULAR MORBIDITY IN TYPE 2 DIABETES MELLITUS PATIENTS. 血清磷是2型糖尿病患者心血管疾病的危险因素。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-03-01 DOI: 10.20471/acc.2025.64.01.06

Dajana Katičić, Josipa Josipović, Marko Lucijanić, Tonko Gulin, Marijana Lukšić Puljak, Draško Pavlović

{"title":"SERUM PHOSPHORUS AS A RISK FACTOR FOR CARDIOVASCULAR MORBIDITY IN TYPE 2 DIABETES MELLITUS PATIENTS.","authors":"Dajana Katičić, Josipa Josipović, Marko Lucijanić, Tonko Gulin, Marijana Lukšić Puljak, Draško Pavlović","doi":"10.20471/acc.2025.64.01.06","DOIUrl":"10.20471/acc.2025.64.01.06","url":null,"abstract":"Phosphorus plays an important role in many physiological functions. Numerous studies have linked phosphorus concentration to cardiovascular (CV) disease and mortality rates. In this study, we investigated the association between high-normal serum phosphorus levels and CV morbidity in patients with type 2 diabetes. Two groups of patients with type 2 diabetes were studied, comprising both males and females aged 18 years and older. One group (140 subjects) had no CV events, while the other group (140 subjects) had one or more CV events. In both groups, we collected fasting laboratory values, medical history, and examination findings. Serum phosphorus levels were statistically significant- ly higher in patients with CV events and had statistically significant but relatively modest discriminatory properties (AUC 0.591; 95% confidence interval (CI) 0.531-0.649; p=0.008). A univariate logistic re- gression model of serum phosphorus as a continuous variable revealed a statistically significant associ- ation with the presence of a cardiovascular event (odds ratio (OR) 7.1849, 95% CI 1.7728 - 29.1190; p=0.0057). For each 1 mmol/L increase in serum phosphorus, the probability of a CV event increased 7.4-fold. After a multivariable logistic regression model, serum phosphorus was associated with a CV event (p=0.0016, OR 16.6), regardless of age, sex, total cholesterol, and systolic blood pressure.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"64 1","pages":"50-59"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145666787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UNILATERAL OPTIC NEUROPATHY AFTER COMPRESSIVE THORACIC INJURY: A CASE REPORT. 胸椎压缩性损伤后单侧视神经病变1例。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-03-01 DOI: 10.20471/acc.2025.64.01.18

Branimir Cerovski, Tomislav Vidović, Smiljka Popović Suić, Ivan Škegro

引用次数: 0

ENDONASAL LEISHMANIASIS IN A FROZEN SECTION BIOPSY SPECIMEN. 鼻内利什曼病的冰冻切片活检标本。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-03-01 DOI: 10.20471/acc.2025.64.01.20

Alma Demirović, Marko Grgić, Božo Krušlin, Davor Tomas

{"title":"ENDONASAL LEISHMANIASIS IN A FROZEN SECTION BIOPSY SPECIMEN.","authors":"Alma Demirović, Marko Grgić, Božo Krušlin, Davor Tomas","doi":"10.20471/acc.2025.64.01.20","DOIUrl":"10.20471/acc.2025.64.01.20","url":null,"abstract":"We present a case of endonasal leishmaniasis diagnosed on a frozen section biopsy specimen obtained from a 47-year-old woman treated with corticosteroids and anti-TNFα for rheumatoid arthritis. Similar cases of isolated mucosal leishmaniasis have not yet been reported in Croatia. Microscopic analysis of the biopsy specimen sent for frozen sections revealed Leishmania amastigotes in macrophages infiltrating nasal mucosa. Subsequent communication with the referring clinician revealed that the patient had been diagnosed with visceral leishmaniasis 13 years prior to current biopsy. Thus, the present nasal lesion was interpreted as a solitary lesion related to reactivation of the previous infection. She received liposomal amphotericin B which led to prompt amelioration of the lesion. As shown in the present case, clinical presentation of leishmaniasis is unspecific and can mimic many other conditions, especially in the setting of concomitant immunosuppressive and anti-inflammatory treatment. It is important to be aware of this entity in order to treat such patients properly.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"64 1","pages":"174-177"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145666759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ETIOLOGY OF URETHRAL STRICTURE: A TERTIARY CENTER'S EXPERIENCE. 尿道狭窄病因学：三级中心的经验。

IF 0.8 4区医学

Acta clinica Croatica Pub Date : 2025-03-01 DOI: 10.20471/acc.2025.64.01.07

Miodrag Aćimović, Veljko Šantric, Nebojša Prijović, Uroš Babić, Branko Stanković, Miloš Petrović, Marko Milosavljević, Kristina Božović, Jovan Hadži-Đokić

{"title":"ETIOLOGY OF URETHRAL STRICTURE: A TERTIARY CENTER'S EXPERIENCE.","authors":"Miodrag Aćimović, Veljko Šantric, Nebojša Prijović, Uroš Babić, Branko Stanković, Miloš Petrović, Marko Milosavljević, Kristina Božović, Jovan Hadži-Đokić","doi":"10.20471/acc.2025.64.01.07","DOIUrl":"10.20471/acc.2025.64.01.07","url":null,"abstract":"Urethral stricture is a complex disease with an etiology that remains insufficiently studied. The frequency of etiological factors associated with urethral stricture has undergone significant changes in recent decades, considering geographical factors, socioeconomic characteristics of the population, and the different etiological factors present in developed and developing countries. We retrospectively collected data from 146 patients who underwent urethroplasty for urethral stricture between 2009 and 2019 at the University Clinical Center of Serbia (Belgrade, Serbia). The patients with urethral stricture were divided into several groups based on their age and the localization of the stricture. Eleven causes of urethral stricture were identified. Urethral catheterization was the leading cause of strictures, regardless of age, accounting for 48.6% of all patients (p<0.001). The most common localization was the penile urethra, accounting for 41.8% of patients (p<0.001), whereas posterior strictures were observed in only 5 patients (3.4%). Considering etiology, iatrogenic (catheterization) and idiopathic urethral stenosis are the predominant factors. Careful urethral manipulation during catheterization is crucial, as it contributes to the prevention of the most common etiological factor of urethral stricture.","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"64 1","pages":"60-66"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145666698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0